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The map label for this gene is suhB [H]

Identifier: 209549930

GI number: 209549930

Start: 2406894

End: 2407724

Strand: Reverse

Name: suhB [H]

Synonym: Rleg2_2346

Alternate gene names: 209549930

Gene position: 2407724-2406894 (Counterclockwise)

Preceding gene: 209549931

Following gene: 209549929

Centisome position: 53.06

GC content: 67.39

Gene sequence:

>831_bases
GTGAGGGAGATTTCCGATGCGCTCCTCCGCGCGCTGATGGAGGATATGCGCCGGGCGGCGGAGGCGGAAATCCTGCCCCG
CTTCCACGGTGTCACCGCCGAGAGCATCCGCACCAAGACCGCGCCCGACGATCTGGTGACCGATGCCGATCTCGGCGCCG
AACGGCGGCTCGCCGAGGCGCTTTCGGCGCGCTTCCCACAAGCGCTGCTCATCGGTGAAGAGGCGGTTTCTGTCGATCCC
GCCATTCTGGCGCGGCTCGCTGATGCCGATCTCGCCGTCATCGTCGATCCTGTCGACGGCACCTGGAATTTCGCCCATGG
TCTGCCGCTCTTCGGCATGATCGTGGCGGTCGTCGCGGGCGGGGAAACCGTGGCCGGACTGATCCACTATCCCGTGACCG
GCGATTTCCTCGCCGCCCGGCCAGGGCGAGGGGCGTGGCACATTGCCCGGGACGGTACGGAGACCCGCCTTGCGGTCGCA
CCGCCGTCACCCGTCGGTGAGATGCACGGCTTCGTGCCGCTGCACATGTTCCCCGCTGAGGAGCAGCCGGCCTATGCGCA
GGGCCTGCTGCGCTTTGCCCGCACCACCACATGGCGCTGCTCGGCCTATGAATACCGGGCGGTGGCATCCGGCGCGATGA
GCTTTGCCCTGAACGCCGAGCTCAAACCCTGGGACCACGCCGCCGGCGTCTTGATCCACTGCGAAGCCGGCGGCTATGGC
GCGCTGCTCACCGGCGAAGCCTATCAGGCGGCGATGACCAGGGGAAGGTTGCTGTTGGCACCGGATGGGGAGAGTTGGGA
AGCGATACGCCGAGGCTTTACGGAGAAGTGA

Upstream 100 bases:

>100_bases
ATCCCGATGCGATCTGGGGCCGGATGATGGCGTCAGGCATCAGCGTTATCCAGACCGACCAGCCGGCCGCGCTCAAGGCC
TATATCGAGGCGCGCCAGCG

Downstream 100 bases:

>100_bases
TAGCCTCGGCACACTGGCGGAAAGGCTGGCAAGGGCGTTCATTCAAGGCGGAAGAGCCGCAAAGACAGGCCCCCGTGAGG
AGCGGAGGTCGCGGCGGACG

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MREISDALLRALMEDMRRAAEAEILPRFHGVTAESIRTKTAPDDLVTDADLGAERRLAEALSARFPQALLIGEEAVSVDP
AILARLADADLAVIVDPVDGTWNFAHGLPLFGMIVAVVAGGETVAGLIHYPVTGDFLAARPGRGAWHIARDGTETRLAVA
PPSPVGEMHGFVPLHMFPAEEQPAYAQGLLRFARTTTWRCSAYEYRAVASGAMSFALNAELKPWDHAAGVLIHCEAGGYG
ALLTGEAYQAAMTRGRLLLAPDGESWEAIRRGFTEK

Sequences:

>Translated_276_residues
MREISDALLRALMEDMRRAAEAEILPRFHGVTAESIRTKTAPDDLVTDADLGAERRLAEALSARFPQALLIGEEAVSVDP
AILARLADADLAVIVDPVDGTWNFAHGLPLFGMIVAVVAGGETVAGLIHYPVTGDFLAARPGRGAWHIARDGTETRLAVA
PPSPVGEMHGFVPLHMFPAEEQPAYAQGLLRFARTTTWRCSAYEYRAVASGAMSFALNAELKPWDHAAGVLIHCEAGGYG
ALLTGEAYQAAMTRGRLLLAPDGESWEAIRRGFTEK
>Mature_276_residues
MREISDALLRALMEDMRRAAEAEILPRFHGVTAESIRTKTAPDDLVTDADLGAERRLAEALSARFPQALLIGEEAVSVDP
AILARLADADLAVIVDPVDGTWNFAHGLPLFGMIVAVVAGGETVAGLIHYPVTGDFLAARPGRGAWHIARDGTETRLAVA
PPSPVGEMHGFVPLHMFPAEEQPAYAQGLLRFARTTTWRCSAYEYRAVASGAMSFALNAELKPWDHAAGVLIHCEAGGYG
ALLTGEAYQAAMTRGRLLLAPDGESWEAIRRGFTEK

Specific function: Displays a 20-fold higher rate of hydrolysis of the D isoform of inositol 1-phosphate than of the L isoform [H]

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=212, Percent_Identity=29.2452830188679, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1788882, Length=218, Percent_Identity=27.5229357798165, Blast_Score=76, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193202572, Length=233, Percent_Identity=28.3261802575107, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193202570, Length=243, Percent_Identity=28.3950617283951, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357957, Length=222, Percent_Identity=28.3783783783784, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357303, Length=216, Percent_Identity=30.0925925925926, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24664922, Length=211, Percent_Identity=31.7535545023697, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29656; Mature: 29656

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00629 IMP_1 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREISDALLRALMEDMRRAAEAEILPRFHGVTAESIRTKTAPDDLVTDADLGAERRLAEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHCCCCCCCHHHHHHHH
LSARFPQALLIGEEAVSVDPAILARLADADLAVIVDPVDGTWNFAHGLPLFGMIVAVVAG
HHHHCCCEEEECCHHHCCCHHHHHHHCCCCEEEEEECCCCCCCHHCCCCHHHHHHHHHCC
GETVAGLIHYPVTGDFLAARPGRGAWHIARDGTETRLAVAPPSPVGEMHGFVPLHMFPAE
CCCEEEEEECCCCCCEEEECCCCCEEEEECCCCCCEEEECCCCCHHHHCCCEEEEEECCC
EQPAYAQGLLRFARTTTWRCSAYEYRAVASGAMSFALNAELKPWDHAAGVLIHCEAGGYG
CCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHEEEECCCCCCCCCCCCEEEEECCCCCE
ALLTGEAYQAAMTRGRLLLAPDGESWEAIRRGFTEK
EEEECHHHHHHHHCCEEEECCCCCCHHHHHCCCCCC
>Mature Secondary Structure
MREISDALLRALMEDMRRAAEAEILPRFHGVTAESIRTKTAPDDLVTDADLGAERRLAEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHCCCCCCCHHHHHHHH
LSARFPQALLIGEEAVSVDPAILARLADADLAVIVDPVDGTWNFAHGLPLFGMIVAVVAG
HHHHCCCEEEECCHHHCCCHHHHHHHCCCCEEEEEECCCCCCCHHCCCCHHHHHHHHHCC
GETVAGLIHYPVTGDFLAARPGRGAWHIARDGTETRLAVAPPSPVGEMHGFVPLHMFPAE
CCCEEEEEECCCCCCEEEECCCCCEEEEECCCCCCEEEECCCCCHHHHCCCEEEEEECCC
EQPAYAQGLLRFARTTTWRCSAYEYRAVASGAMSFALNAELKPWDHAAGVLIHCEAGGYG
CCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHHEEEECCCCCCCCCCCCEEEEECCCCCE
ALLTGEAYQAAMTRGRLLLAPDGESWEAIRRGFTEK
EEEECHHHHHHHHCCEEEECCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9720201; 10360571; 10508089 [H]