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The map label for this gene is qoxC [H]

Identifier: 209549852

GI number: 209549852

Start: 2322426

End: 2323145

Strand: Reverse

Name: qoxC [H]

Synonym: Rleg2_2265

Alternate gene names: 209549852

Gene position: 2323145-2322426 (Counterclockwise)

Preceding gene: 209549853

Following gene: 209549851

Centisome position: 51.19

GC content: 61.94

Gene sequence:

>720_bases
ATGGCACAGACGATCGAGACGCACGGCGAGCCAGGGCTGCGGCCGGCCGGTCTGCGCGGTGTCGCCGCCGATTTCAGCTC
GGATCAGCGCGCCTTCAAGACCGCCTCCTGGGGCAAGGCGATGATGTGGATCTTTCTGCTCAGCGACACCTTCGTCTTCG
GCTGTTTCCTGATCGCCTATATGACCGCCCGCATGTCGACGCCCGTCCCATGGCCCAATCCGAGCGAGGTTTTCGCGCTG
CATATCGGCGGGCAGGATGTTCCGCTGATCCTGATCGCGATCATGACCTTCGTGCTGATCTCGAGCAGCGGCACCATGGC
GATGGCGGTCAATTTCGGCTATCGCCGCGACCGCCACAAGACCGCGGTGCTGATGCTGCTGACGGCGCTTCTCGGGGCAT
GCTTTGTCGGCATGCAGGCTTTCGAATGGACCAAGCTGATCACCGAAGGCGTGCGCCCCTGGGAGAACCCGTGGGGGGCC
GCACAGTTCGGATCGACCTTCTTCATGATCACCGGCTTTCACGGCACCCACGTGACGATCGGCGTAATCTTCCTCATCAT
TACCGCCCGCAAGGTCTGGCGGGGCGATTTCGACGTGGAGCGGCGCGGCTTTTTCACCAGCCGGAGAGGGCGCTACGAGG
CCGTCGAGATCATGGGTCTCTACTGGCATTTCGTCGACCTGGTCTGGGTCTTCATCTTCGCGTTTTTCTATCTGTGGTGA

Upstream 100 bases:

>100_bases
TCTGGCTTCTGCTTTTCGCGCTTTTTGCCGGATGGGCGAATGATTTCGTCGATCTCTGCCGGACGTTGTTGAAATAGGGG
CTGAACCAGGAGGTTTGCAG

Downstream 100 bases:

>100_bases
GGTCGTCATGAGCGAGACAACAGCGCATGGGCAAAGCCCGCATGCACAGGCCCCGCATGCACAAGATCACGGGCAGCAGC
ATCCGATCGGGCTCTATTTC

Product: cytochrome C oxidase subunit III

Products: ferricytochrome c; H2O

Alternate protein names: Quinol oxidase polypeptide III [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MAQTIETHGEPGLRPAGLRGVAADFSSDQRAFKTASWGKAMMWIFLLSDTFVFGCFLIAYMTARMSTPVPWPNPSEVFAL
HIGGQDVPLILIAIMTFVLISSSGTMAMAVNFGYRRDRHKTAVLMLLTALLGACFVGMQAFEWTKLITEGVRPWENPWGA
AQFGSTFFMITGFHGTHVTIGVIFLIITARKVWRGDFDVERRGFFTSRRGRYEAVEIMGLYWHFVDLVWVFIFAFFYLW

Sequences:

>Translated_239_residues
MAQTIETHGEPGLRPAGLRGVAADFSSDQRAFKTASWGKAMMWIFLLSDTFVFGCFLIAYMTARMSTPVPWPNPSEVFAL
HIGGQDVPLILIAIMTFVLISSSGTMAMAVNFGYRRDRHKTAVLMLLTALLGACFVGMQAFEWTKLITEGVRPWENPWGA
AQFGSTFFMITGFHGTHVTIGVIFLIITARKVWRGDFDVERRGFFTSRRGRYEAVEIMGLYWHFVDLVWVFIFAFFYLW
>Mature_238_residues
AQTIETHGEPGLRPAGLRGVAADFSSDQRAFKTASWGKAMMWIFLLSDTFVFGCFLIAYMTARMSTPVPWPNPSEVFALH
IGGQDVPLILIAIMTFVLISSSGTMAMAVNFGYRRDRHKTAVLMLLTALLGACFVGMQAFEWTKLITEGVRPWENPWGAA
QFGSTFFMITGFHGTHVTIGVIFLIITARKVWRGDFDVERRGFFTSRRGRYEAVEIMGLYWHFVDLVWVFIFAFFYLW

Specific function: Catalyzes quinol oxidation with the concomitant reduction of oxygen to water [H]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=155, Percent_Identity=33.5483870967742, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786633, Length=196, Percent_Identity=31.1224489795918, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014246
- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: 1.9.3.1

Molecular weight: Translated: 27097; Mature: 26966

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTIETHGEPGLRPAGLRGVAADFSSDQRAFKTASWGKAMMWIFLLSDTFVFGCFLIAY
CCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MTARMSTPVPWPNPSEVFALHIGGQDVPLILIAIMTFVLISSSGTMAMAVNFGYRRDRHK
HHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
TAVLMLLTALLGACFVGMQAFEWTKLITEGVRPWENPWGAAQFGSTFFMITGFHGTHVTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCEEEEEECCCCCHHHH
GVIFLIITARKVWRGDFDVERRGFFTSRRGRYEAVEIMGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
AQTIETHGEPGLRPAGLRGVAADFSSDQRAFKTASWGKAMMWIFLLSDTFVFGCFLIAY
CCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MTARMSTPVPWPNPSEVFALHIGGQDVPLILIAIMTFVLISSSGTMAMAVNFGYRRDRHK
HHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHH
TAVLMLLTALLGACFVGMQAFEWTKLITEGVRPWENPWGAAQFGSTFFMITGFHGTHVTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCEEEEEECCCCCHHHH
GVIFLIITARKVWRGDFDVERRGFFTSRRGRYEAVEIMGLYWHFVDLVWVFIFAFFYLW
HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrocytochrome c; O2

Specific reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA