Click here to switch to the map view.

The map label for this gene is ubiA [H]

Identifier: 209549823

GI number: 209549823

Start: 2289667

End: 2290581

Strand: Direct

Name: ubiA [H]

Synonym: Rleg2_2235

Alternate gene names: 209549823

Gene position: 2289667-2290581 (Clockwise)

Preceding gene: 209549822

Following gene: 209549824

Centisome position: 50.46

GC content: 62.51

Gene sequence:

>915_bases
ATGATGACTTCGAGCCATCCCGACCTCAGTGACATCCACCATGGCGACTGGGTGGATCGCCGATTGCCGGCCGCATGGCG
GCCTTATACGCGGCTCGCGCGGCTGGATCGGCCAGTCGGAATATGGCTGACGCTTTTCCCGTGCTGGGCTGCCCTCATCC
AGGCATCGCGCGGCCTGCCGGACCTCGGTGAACTCGTGATCTTCTCTCTCGGCGCCCTGCTGATGAGAAGCGCCGGCTCC
ACAGTCAACGACATCGCCGATCGGAATTTTGACGCTCACGTTGAGCGGACCCGTTTTCGTCCACTTGCAAGCGGAGACAT
CGGCACGCTGCAGGCCTTCGTCTTCCTGGCCGCCGAACTCATGCTCGCAGCCTCGCTTCTGTTTTTCCTGACGCCTTACA
CGCGTTTGATCGCAATATCGGTTCTGCCGCTCGTCTTCGTCTATCCGCTCTGCAAGCGCATCACCCACTGGCCCCAGGCC
GTGCTGAGCGCGGCGTTCAACTGGGGCATGCTGATGGCATGGGCCGAGATTGCCGGCCATATCCCGGCCGGCGCTGTGCT
GATGTGGGCCGGAGCGATCGCCTGGCAGATCGGCTATGATACGGTCTATGCCTATGTGGACGTCAGGGATGACACCCGCC
TCGGCTTGAAATCGACGGCAATCCTGTTCGGCCGGCGCGGCAAGATGTGGATCGGCTTGTTCTATGCTCTGGCCGTTGCG
GCGTGGTCGATCGGGGGCTGGCTGTTGGAGATGTCGCCACCTTATGCGATCGGAATGCTGGTGATCGCAGCCCACCTTGC
CTGGCAGACCCGGCGGATCGACCTTGCCCGCCCTGACCTGAATTATCGCCTGTTCCTCGCCAATATCCTGACGGGCGTGC
TGCTCGCCGGCACGGCTATGTCGGGCACATGGTAG

Upstream 100 bases:

>100_bases
AGGCTGTCGTTCGTTGCAGACAGCCGTTGATCCGCTTGCAAAAAATCCTATTCTGGCCGTCGCCATCCCGGCCGCTGCGA
CAGGAAATTTGGATTCTCTC

Downstream 100 bases:

>100_bases
ACAGCTCGAGGACGTGATACCGATGACCTATTTCAAACAAGCCGCGTTCGCTGCCACCATGATGCTGGCAGCAACGATGA
CACCCCTGCATCAGGCCCAT

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MMTSSHPDLSDIHHGDWVDRRLPAAWRPYTRLARLDRPVGIWLTLFPCWAALIQASRGLPDLGELVIFSLGALLMRSAGS
TVNDIADRNFDAHVERTRFRPLASGDIGTLQAFVFLAAELMLAASLLFFLTPYTRLIAISVLPLVFVYPLCKRITHWPQA
VLSAAFNWGMLMAWAEIAGHIPAGAVLMWAGAIAWQIGYDTVYAYVDVRDDTRLGLKSTAILFGRRGKMWIGLFYALAVA
AWSIGGWLLEMSPPYAIGMLVIAAHLAWQTRRIDLARPDLNYRLFLANILTGVLLAGTAMSGTW

Sequences:

>Translated_304_residues
MMTSSHPDLSDIHHGDWVDRRLPAAWRPYTRLARLDRPVGIWLTLFPCWAALIQASRGLPDLGELVIFSLGALLMRSAGS
TVNDIADRNFDAHVERTRFRPLASGDIGTLQAFVFLAAELMLAASLLFFLTPYTRLIAISVLPLVFVYPLCKRITHWPQA
VLSAAFNWGMLMAWAEIAGHIPAGAVLMWAGAIAWQIGYDTVYAYVDVRDDTRLGLKSTAILFGRRGKMWIGLFYALAVA
AWSIGGWLLEMSPPYAIGMLVIAAHLAWQTRRIDLARPDLNYRLFLANILTGVLLAGTAMSGTW
>Mature_304_residues
MMTSSHPDLSDIHHGDWVDRRLPAAWRPYTRLARLDRPVGIWLTLFPCWAALIQASRGLPDLGELVIFSLGALLMRSAGS
TVNDIADRNFDAHVERTRFRPLASGDIGTLQAFVFLAAELMLAASLLFFLTPYTRLIAISVLPLVFVYPLCKRITHWPQA
VLSAAFNWGMLMAWAEIAGHIPAGAVLMWAGAIAWQIGYDTVYAYVDVRDDTRLGLKSTAILFGRRGKMWIGLFYALAVA
AWSIGGWLLEMSPPYAIGMLVIAAHLAWQTRRIDLARPDLNYRLFLANILTGVLLAGTAMSGTW

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=276, Percent_Identity=40.5797101449275, Blast_Score=208, Evalue=5e-54,
Organism=Escherichia coli, GI1790473, Length=274, Percent_Identity=40.5109489051095, Blast_Score=171, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17553718, Length=296, Percent_Identity=36.8243243243243, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI32565247, Length=277, Percent_Identity=37.1841155234657, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17553720, Length=334, Percent_Identity=32.9341317365269, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI32565245, Length=162, Percent_Identity=40.7407407407407, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI32565243, Length=162, Percent_Identity=40.7407407407407, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324370, Length=287, Percent_Identity=37.9790940766551, Blast_Score=176, Evalue=3e-45,
Organism=Drosophila melanogaster, GI21355567, Length=279, Percent_Identity=41.9354838709677, Blast_Score=221, Evalue=6e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33741; Mature: 33741

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTSSHPDLSDIHHGDWVDRRLPAAWRPYTRLARLDRPVGIWLTLFPCWAALIQASRGLP
CCCCCCCCHHHCCCCCCHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
DLGELVIFSLGALLMRSAGSTVNDIADRNFDAHVERTRFRPLASGDIGTLQAFVFLAAEL
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
MLAASLLFFLTPYTRLIAISVLPLVFVYPLCKRITHWPQAVLSAAFNWGMLMAWAEIAGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPAGAVLMWAGAIAWQIGYDTVYAYVDVRDDTRLGLKSTAILFGRRGKMWIGLFYALAVA
CCHHHHHHHHHHHHHEECCCEEEEEEEECCCCCCCHHHHHHEECCCCCHHHHHHHHHHHH
AWSIGGWLLEMSPPYAIGMLVIAAHLAWQTRRIDLARPDLNYRLFLANILTGVLLAGTAM
HHHHCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCC
SGTW
CCCC
>Mature Secondary Structure
MMTSSHPDLSDIHHGDWVDRRLPAAWRPYTRLARLDRPVGIWLTLFPCWAALIQASRGLP
CCCCCCCCHHHCCCCCCHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
DLGELVIFSLGALLMRSAGSTVNDIADRNFDAHVERTRFRPLASGDIGTLQAFVFLAAEL
HHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
MLAASLLFFLTPYTRLIAISVLPLVFVYPLCKRITHWPQAVLSAAFNWGMLMAWAEIAGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IPAGAVLMWAGAIAWQIGYDTVYAYVDVRDDTRLGLKSTAILFGRRGKMWIGLFYALAVA
CCHHHHHHHHHHHHHEECCCEEEEEEEECCCCCCCHHHHHHEECCCCCHHHHHHHHHHHH
AWSIGGWLLEMSPPYAIGMLVIAAHLAWQTRRIDLARPDLNYRLFLANILTGVLLAGTAM
HHHHCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCC
SGTW
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA