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The map label for this gene is mutT [C]

Identifier: 209549766

GI number: 209549766

Start: 2230391

End: 2230792

Strand: Direct

Name: mutT [C]

Synonym: Rleg2_2175

Alternate gene names: 209549766

Gene position: 2230391-2230792 (Clockwise)

Preceding gene: 209549765

Following gene: 209549772

Centisome position: 49.15

GC content: 61.19

Gene sequence:

>402_bases
ATGCCCGAGATCGCAATCGGCGCATTGATCGGGAATGGGAGCGTTCTTCTCGCCAGGCGAAATTCGGAGCGCCGGACGCA
TCCGGATCGGTGGAGCCTACCGGGCGGCCATGTCGAAGACGGCGAAGACGCCGAGACGGCAATGCGCCGCGAATTGCTGG
AAGAAATCGGCGTGACGCCACAGCACTCGCTGTTTGCCGGAGAGTTCGTTTCGGAAAGCCCGCCCGGGGCATCCGCCACT
TTCCATGTCTATCACGTCGACCAATGGCAAGGCTCTCCGCGACTTATCGGCGATGAACACACGGCGCTCAGATGGTTTAC
CGCCGCGGAGATAGAATGCGAAACCGAACTGGCGCCGCCCCAGCTTAGTGAAATGCTCCTGAAGCTGCTCAGGCGGGAGT
GA

Upstream 100 bases:

>100_bases
CATCGTACAGAAATCGGTGACGCGGCTGCGCGACAACCTGCTGCGGGCGCAGGCGGAGCCGCAAAAATCATGATCGCGGC
ACATGTCGGCATTCGGTGAT

Downstream 100 bases:

>100_bases
CCCGCAAGACACGATGAAGGAGGACAGGCAGTGCTAACCCCAGCCTACAACGCCCACGACCGCGCCACATCCTCCAGAGC
GCCCTCCTCCATCATCTCGG

Product: NUDIX hydrolase

Products: 8-Oxo-Dgmp; Pyrophosphate. [C]

Alternate protein names: NTP Pyrophosphohydrolase Protein MutT/Nudix Family; MutT/NUDIX Family NTP Pyrophosphohydrolase; Mutator MutT Protein; Nudix Hydrolase

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MPEIAIGALIGNGSVLLARRNSERRTHPDRWSLPGGHVEDGEDAETAMRRELLEEIGVTPQHSLFAGEFVSESPPGASAT
FHVYHVDQWQGSPRLIGDEHTALRWFTAAEIECETELAPPQLSEMLLKLLRRE

Sequences:

>Translated_133_residues
MPEIAIGALIGNGSVLLARRNSERRTHPDRWSLPGGHVEDGEDAETAMRRELLEEIGVTPQHSLFAGEFVSESPPGASAT
FHVYHVDQWQGSPRLIGDEHTALRWFTAAEIECETELAPPQLSEMLLKLLRRE
>Mature_132_residues
PEIAIGALIGNGSVLLARRNSERRTHPDRWSLPGGHVEDGEDAETAMRRELLEEIGVTPQHSLFAGEFVSESPPGASATF
HVYHVDQWQGSPRLIGDEHTALRWFTAAEIECETELAPPQLSEMLLKLLRRE

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 14823; Mature: 14692

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEIAIGALIGNGSVLLARRNSERRTHPDRWSLPGGHVEDGEDAETAMRRELLEEIGVTP
CCCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
QHSLFAGEFVSESPPGASATFHVYHVDQWQGSPRLIGDEHTALRWFTAAEIECETELAPP
CCCEEECCCCCCCCCCCCEEEEEEEEECCCCCCCEECCCCCEEEEEEECEEEECCCCCCH
QLSEMLLKLLRRE
HHHHHHHHHHHCC
>Mature Secondary Structure 
PEIAIGALIGNGSVLLARRNSERRTHPDRWSLPGGHVEDGEDAETAMRRELLEEIGVTP
CCEEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
QHSLFAGEFVSESPPGASATFHVYHVDQWQGSPRLIGDEHTALRWFTAAEIECETELAPP
CCCEEECCCCCCCCCCCCEEEEEEEEECCCCCCCEECCCCCEEEEEEECEEEECCCCCCH
QLSEMLLKLLRRE
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Oxo-Dgtp; H2O [C]

Specific reaction: 8-Oxo-Dgtp + H2O = 8-Oxo-Dgmp + Pyrophosphate. [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA