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The map label for this gene is cobO [H]

Identifier: 209549723

GI number: 209549723

Start: 2187010

End: 2187645

Strand: Reverse

Name: cobO [H]

Synonym: Rleg2_2130

Alternate gene names: 209549723

Gene position: 2187645-2187010 (Counterclockwise)

Preceding gene: 209549724

Following gene: 209549719

Centisome position: 48.21

GC content: 60.53

Gene sequence:

>636_bases
ATGAGCGACGAAATCCCGGACAACGAAACGGGCAAGGACGATGCGCGCCACGCCGAGAAGATGGCGAAGAAGAAGGCCGC
GCGCGACAAGATCATGGCGACCAAGACCGACGGCAAGGGGCTGATCATCGTCCATACCGGCAAGGGCAAGGGCAAATCAT
CCGCCGCCTTCGGCATGATCTTCCGCCACATCGCCCATGGTAAACCCTCGGCCGTCGTGCAGTTCATCAAGGGCGCGATG
TGGACCGGCGAGCGGGATCTGATCGAGAAGCATTTCTCCGATCTCTGCCAGTTCCACACCATGGGTGAGGGGTTCACCTG
GGAAACGCAGGACCGAGCCCGCGACGTTGCCGCCGCCTCGGCGGCCTGGGAAAAGGCCAAGGAGCTGATCCGCGACGAGC
GCAATTCGATGGTGCTGCTCGACGAGATCAACATCGCGCTGCGCTACGACTATCTCGATATCAACGATGTGGTAGGATTC
CTGAAGACCGAGAAGCCCGCCATGACCCATGTCGTGCTGACGGGGCGCAACGCTAGGGAAGAACTGATCGAGATCGCCGA
TCTTGTGACCGAGATGGAGCTCGTCAAACATCCCTTCCGCTCCGGCATCAAGGGCCAGCCGGGGGTAGAATTCTAG

Upstream 100 bases:

>100_bases
TGGCGGCTCGGCTGCGCGAGGCGATAGACCGCAGCCTTTGGACGCCGCGCAGCAATTCGGCCCGGTTCGACCTGGCCATC
CAACAGAATGAGGTGAACCG

Downstream 100 bases:

>100_bases
GCATCAGTTGAGGGAAAGGGTGCGCAGGATCGCGGCCGTTTTCTTATCCGCCGGGAAGAAGGATTCCACGGCCAGTTCCG
ACAGAGTGATGTCGACGGGC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSDEIPDNETGKDDARHAEKMAKKKAARDKIMATKTDGKGLIIVHTGKGKGKSSAAFGMIFRHIAHGKPSAVVQFIKGAM
WTGERDLIEKHFSDLCQFHTMGEGFTWETQDRARDVAAASAAWEKAKELIRDERNSMVLLDEINIALRYDYLDINDVVGF
LKTEKPAMTHVVLTGRNAREELIEIADLVTEMELVKHPFRSGIKGQPGVEF

Sequences:

>Translated_211_residues
MSDEIPDNETGKDDARHAEKMAKKKAARDKIMATKTDGKGLIIVHTGKGKGKSSAAFGMIFRHIAHGKPSAVVQFIKGAM
WTGERDLIEKHFSDLCQFHTMGEGFTWETQDRARDVAAASAAWEKAKELIRDERNSMVLLDEINIALRYDYLDINDVVGF
LKTEKPAMTHVVLTGRNAREELIEIADLVTEMELVKHPFRSGIKGQPGVEF
>Mature_210_residues
SDEIPDNETGKDDARHAEKMAKKKAARDKIMATKTDGKGLIIVHTGKGKGKSSAAFGMIFRHIAHGKPSAVVQFIKGAMW
TGERDLIEKHFSDLCQFHTMGEGFTWETQDRARDVAAASAAWEKAKELIRDERNSMVLLDEINIALRYDYLDINDVVGFL
KTEKPAMTHVVLTGRNAREELIEIADLVTEMELVKHPFRSGIKGQPGVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=198, Percent_Identity=42.9292929292929, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23582; Mature: 23451

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDEIPDNETGKDDARHAEKMAKKKAARDKIMATKTDGKGLIIVHTGKGKGKSSAAFGMI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHHHHHH
FRHIAHGKPSAVVQFIKGAMWTGERDLIEKHFSDLCQFHTMGEGFTWETQDRARDVAAAS
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AAWEKAKELIRDERNSMVLLDEINIALRYDYLDINDVVGFLKTEKPAMTHVVLTGRNARE
HHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCHHH
ELIEIADLVTEMELVKHPFRSGIKGQPGVEF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SDEIPDNETGKDDARHAEKMAKKKAARDKIMATKTDGKGLIIVHTGKGKGKSSAAFGMI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCHHHHHHH
FRHIAHGKPSAVVQFIKGAMWTGERDLIEKHFSDLCQFHTMGEGFTWETQDRARDVAAAS
HHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
AAWEKAKELIRDERNSMVLLDEINIALRYDYLDINDVVGFLKTEKPAMTHVVLTGRNARE
HHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCHHH
ELIEIADLVTEMELVKHPFRSGIKGQPGVEF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]