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The map label for this gene is csxA [H]

Identifier: 209549687

GI number: 209549687

Start: 2153586

End: 2156045

Strand: Reverse

Name: csxA [H]

Synonym: Rleg2_2094

Alternate gene names: 209549687

Gene position: 2156045-2153586 (Counterclockwise)

Preceding gene: 209549688

Following gene: 209549686

Centisome position: 47.51

GC content: 60.77

Gene sequence:

>2460_bases
GTGACGCAACAAACGCCCCCCTCCAACATCGACCTTTCCGGTTCGTGGCAGCTCGCCTCCGTCGACGGCGAGATTCGCAC
TGCGATCATGCTGCCGGGCGACGTGCATACCGCGCTCCACCGGGCAGGGCTGATCCCCGATCCCTATTTCGGCCGCAACG
AGGAAAAGGTGCAGTGGGTCGCCGAGCGTGAATGGGCGGTGGAGCGCAGCTTCGCGCTGCCGGAGGTCGATGGCGACTGG
TATCTGGATATCGACTACCTCGACACGGTCGCCAGCGTCCATGTCAACGGCTTCCTGGCGCTCGAAGCCGATAACAGCTT
CCGCCGCTACCGGCCCGATGTGTCCAGCATGTTGAAAGCGGGCGACAATGTCATCCGCATCGTCTTCGCCTCGAACATCG
CGGTCGGGGCCGAGCGGCAGAAGAAGCAGCCCTTCTACATCCCATACAGCACGGGCAATTCGCCGATCCCGGATGGCAAC
ATGCTGCGCAAGCCGCAATGCCATTTCGGCTGGGACTGGAATATCGCCATTGCGCCGTTCGGCCTTTACGGCACGATCGC
GCTGAAGAAGCTCGAGACCGCGCGCATCGAACATGTCGTCACCCGCCAGACGCATAATTTCGACGGATCGGTCGATCTGA
CGGTGACGGCGACGCTCTATTCCAAGGGGCCGAGTATTGCCCAGGTCTATTTCGATCTCGATGGCGAGCGGGTGCGCCTC
GATGTCGGCGTCCATGGCGAGACCCATGTCAACCATCTCTTCCATATCGACAATCCGCGCCTATGGTGGCCTTCCGGCAG
CGGCGAGCAGGCGCTCTATAGCCTGTCCGTCGAATTGCCGACGGATGAGGTGACGAAGCAGATCGGTCTTCGCACCATCG
AGCTGATCACCACGCCGGATGCATCAGGCAGCCGCTTCGCCTTCAAGGTCAATGGCCGCGAGATCTTCTGCCGTGGCGCC
AACTGGATTCCGGCCGACGCGCTGTTTTCGCTGTCGTCGCCTGAAAAGACCCAGGATCTCCTGCAATCGGCCGTAGCCGC
CAACATGAACATGATCCGCGTCTGGGGCGGCGGCTTTTACGAGCAGGATCATTTCTACGATTTGTGCGACCGGCTGGGCC
TGATGGTCTGGCAGGACTTCATGTTTGCCTGCAACCTCTATCCCTCGACTGAAGATTTTCTCGACAATGTGGCTGTTGAG
GTCGACTACCAGGTGCGCCGGCTTTCCTCGCATCCCTCGATCGCGCTCTGGTGCGGTGACAACGAACTTGTGGGAGCACT
CACCTGGTTCGAGCAATCCAGGAAGGACCGCGACCGCTATCTCGTCTCCTACGACCGCCTCAACCGGACGATCGAGCAGG
CGGTGAAGAAGGCGCTGCCCGGCGCGCTCTGGTGGCCGTCGAGCCCGGCCTCGGGCTATCTCGATTTCGGCGATGCCTGG
CATGCCGACGGCTCCGGCGACATGCACTACTGGTCGGTCTGGCACGAGAATAAGTCGTTCGACAATTACCGTTCGGTGCG
GCCGCGCTTCTGCTCGGAATTCGGCTTCCAGTCCTATACCTCGCTACCCGTCATCAAGACCTATGCCGAGGAGAAGGACA
TGAACGTTGCTTCCCCCGTCATGGAACTGCATCAGAAGAACGCCGGCGGCAACGAGCGTATCGCCGGCACGATGTTCCGC
TATTTCCGTTTCCCCAAGGATTTTCCGAACTTCGTCTATCTCTCCCAGATCCAGCAGGGCCTCGCCATCAAGACGGCGGT
GGAATATTGGCGGTCGCTCAAACCGCATTGCATGGGCACGATCTACTGGCAGCTCAACGACACATGGCCGGTCGCCTCCT
GGTCTAGCCTCGACTATGGCGGCCGCTGGAAGGCGATGCATTATCTCGTCAAGCGCTTCTTCCAGCCGGTCGCGGTCGCC
GCCATTCCTTCCGAGGACGGCAAGACGATCCGCTTCTCGCTGGTCAACGACACGCTTGAAGATATCAGCATCGATCTTTC
GATCTCTGCTCTGACGATGAAGGGCGAACGCCTGCACCTGAAAGACGTGCGAGCCGTATGCTCGCCGGATGCGGCGGTGA
CGGCTGCGAGCATCGACGTTTCCGACATTCCCGCCGACACGCTGCTTGCCTGGCATTTCACCGCGTCGAACGGCATGGGC
GGCGAGGGGCATTACGTCAACGGCACCTATAAGGCGCTGGAATTGGAGCCGTCGGGCCTGACCGTCGCTCACGAATATGT
CGAGGAGAGTGGCGCGATCGATATCAACGTCACCGCGAGGGGACTTGCGCTCTTCGTGATGATCGAGACCGAGACGGACG
GCAAATATTCCGACAATGCCTTCGACCTTGCAGCCGGCGGGAGCCGCCGCATCACCTTTACCCCGGCACATCAGCTTGAT
CGCGGTGCCCTTCCGGAGTTCCGCTTCTACGACCTGCATTCCTGCCAATCGGCGGATTGA

Upstream 100 bases:

>100_bases
AGCCCGAGCATGACGGAGAAGACGGGGTCACAACGAACGACAATGACCGGACGGCAATCATGCGCCGTCCATTTCAAAAA
CGTAATTCGGAAACGACATC

Downstream 100 bases:

>100_bases
TCCTTCCCAAGCATGGGCACGAGGCCCGAGGAGAATATGATGACGAAACTCAGCTACCAGCTCTACAGCGCCCGTAATTT
CCAGCCTTATTCGGCGATTT

Product: beta-mannosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 819; Mature: 818

Protein sequence:

>819_residues
MTQQTPPSNIDLSGSWQLASVDGEIRTAIMLPGDVHTALHRAGLIPDPYFGRNEEKVQWVAEREWAVERSFALPEVDGDW
YLDIDYLDTVASVHVNGFLALEADNSFRRYRPDVSSMLKAGDNVIRIVFASNIAVGAERQKKQPFYIPYSTGNSPIPDGN
MLRKPQCHFGWDWNIAIAPFGLYGTIALKKLETARIEHVVTRQTHNFDGSVDLTVTATLYSKGPSIAQVYFDLDGERVRL
DVGVHGETHVNHLFHIDNPRLWWPSGSGEQALYSLSVELPTDEVTKQIGLRTIELITTPDASGSRFAFKVNGREIFCRGA
NWIPADALFSLSSPEKTQDLLQSAVAANMNMIRVWGGGFYEQDHFYDLCDRLGLMVWQDFMFACNLYPSTEDFLDNVAVE
VDYQVRRLSSHPSIALWCGDNELVGALTWFEQSRKDRDRYLVSYDRLNRTIEQAVKKALPGALWWPSSPASGYLDFGDAW
HADGSGDMHYWSVWHENKSFDNYRSVRPRFCSEFGFQSYTSLPVIKTYAEEKDMNVASPVMELHQKNAGGNERIAGTMFR
YFRFPKDFPNFVYLSQIQQGLAIKTAVEYWRSLKPHCMGTIYWQLNDTWPVASWSSLDYGGRWKAMHYLVKRFFQPVAVA
AIPSEDGKTIRFSLVNDTLEDISIDLSISALTMKGERLHLKDVRAVCSPDAAVTAASIDVSDIPADTLLAWHFTASNGMG
GEGHYVNGTYKALELEPSGLTVAHEYVEESGAIDINVTARGLALFVMIETETDGKYSDNAFDLAAGGSRRITFTPAHQLD
RGALPEFRFYDLHSCQSAD

Sequences:

>Translated_819_residues
MTQQTPPSNIDLSGSWQLASVDGEIRTAIMLPGDVHTALHRAGLIPDPYFGRNEEKVQWVAEREWAVERSFALPEVDGDW
YLDIDYLDTVASVHVNGFLALEADNSFRRYRPDVSSMLKAGDNVIRIVFASNIAVGAERQKKQPFYIPYSTGNSPIPDGN
MLRKPQCHFGWDWNIAIAPFGLYGTIALKKLETARIEHVVTRQTHNFDGSVDLTVTATLYSKGPSIAQVYFDLDGERVRL
DVGVHGETHVNHLFHIDNPRLWWPSGSGEQALYSLSVELPTDEVTKQIGLRTIELITTPDASGSRFAFKVNGREIFCRGA
NWIPADALFSLSSPEKTQDLLQSAVAANMNMIRVWGGGFYEQDHFYDLCDRLGLMVWQDFMFACNLYPSTEDFLDNVAVE
VDYQVRRLSSHPSIALWCGDNELVGALTWFEQSRKDRDRYLVSYDRLNRTIEQAVKKALPGALWWPSSPASGYLDFGDAW
HADGSGDMHYWSVWHENKSFDNYRSVRPRFCSEFGFQSYTSLPVIKTYAEEKDMNVASPVMELHQKNAGGNERIAGTMFR
YFRFPKDFPNFVYLSQIQQGLAIKTAVEYWRSLKPHCMGTIYWQLNDTWPVASWSSLDYGGRWKAMHYLVKRFFQPVAVA
AIPSEDGKTIRFSLVNDTLEDISIDLSISALTMKGERLHLKDVRAVCSPDAAVTAASIDVSDIPADTLLAWHFTASNGMG
GEGHYVNGTYKALELEPSGLTVAHEYVEESGAIDINVTARGLALFVMIETETDGKYSDNAFDLAAGGSRRITFTPAHQLD
RGALPEFRFYDLHSCQSAD
>Mature_818_residues
TQQTPPSNIDLSGSWQLASVDGEIRTAIMLPGDVHTALHRAGLIPDPYFGRNEEKVQWVAEREWAVERSFALPEVDGDWY
LDIDYLDTVASVHVNGFLALEADNSFRRYRPDVSSMLKAGDNVIRIVFASNIAVGAERQKKQPFYIPYSTGNSPIPDGNM
LRKPQCHFGWDWNIAIAPFGLYGTIALKKLETARIEHVVTRQTHNFDGSVDLTVTATLYSKGPSIAQVYFDLDGERVRLD
VGVHGETHVNHLFHIDNPRLWWPSGSGEQALYSLSVELPTDEVTKQIGLRTIELITTPDASGSRFAFKVNGREIFCRGAN
WIPADALFSLSSPEKTQDLLQSAVAANMNMIRVWGGGFYEQDHFYDLCDRLGLMVWQDFMFACNLYPSTEDFLDNVAVEV
DYQVRRLSSHPSIALWCGDNELVGALTWFEQSRKDRDRYLVSYDRLNRTIEQAVKKALPGALWWPSSPASGYLDFGDAWH
ADGSGDMHYWSVWHENKSFDNYRSVRPRFCSEFGFQSYTSLPVIKTYAEEKDMNVASPVMELHQKNAGGNERIAGTMFRY
FRFPKDFPNFVYLSQIQQGLAIKTAVEYWRSLKPHCMGTIYWQLNDTWPVASWSSLDYGGRWKAMHYLVKRFFQPVAVAA
IPSEDGKTIRFSLVNDTLEDISIDLSISALTMKGERLHLKDVRAVCSPDAAVTAASIDVSDIPADTLLAWHFTASNGMGG
EGHYVNGTYKALELEPSGLTVAHEYVEESGAIDINVTARGLALFVMIETETDGKYSDNAFDLAAGGSRRITFTPAHQLDR
GALPEFRFYDLHSCQSAD

Specific function: Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration. Has no beta-mannosidase activity [H]

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Secreted, extracellular space [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI84798622, Length=853, Percent_Identity=30.0117233294256, Blast_Score=386, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17550784, Length=721, Percent_Identity=29.126213592233, Blast_Score=336, Evalue=4e-92,
Organism=Drosophila melanogaster, GI24643838, Length=788, Percent_Identity=29.5685279187817, Blast_Score=294, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24643840, Length=771, Percent_Identity=29.7016861219196, Blast_Score=282, Evalue=7e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.165 [H]

Molecular weight: Translated: 92120; Mature: 91989

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQTPPSNIDLSGSWQLASVDGEIRTAIMLPGDVHTALHRAGLIPDPYFGRNEEKVQWV
CCCCCCCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHEE
AEREWAVERSFALPEVDGDWYLDIDYLDTVASVHVNGFLALEADNSFRRYRPDVSSMLKA
HHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHEEEEEEEEEECCCCHHHCCCCHHHHHHC
GDNVIRIVFASNIAVGAERQKKQPFYIPYSTGNSPIPDGNMLRKPQCHFGWDWNIAIAPF
CCCEEEEEEECCEEECCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
GLYGTIALKKLETARIEHVVTRQTHNFDGSVDLTVTATLYSKGPSIAQVYFDLDGERVRL
CCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCEEEEEEECCCCEEEE
DVGVHGETHVNHLFHIDNPRLWWPSGSGEQALYSLSVELPTDEVTKQIGLRTIELITTPD
EEECCCCCCCEEEEEECCCEEECCCCCCCCEEEEEEEECCHHHHHHHHCCEEEEEEECCC
ASGSRFAFKVNGREIFCRGANWIPADALFSLSSPEKTQDLLQSAVAANMNMIRVWGGGFY
CCCCEEEEEECCEEEEEECCCCCCHHHEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCC
EQDHFYDLCDRLGLMVWQDFMFACNLYPSTEDFLDNVAVEVDYQVRRLSSHPSIALWCGD
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCEEEEEEHHHEECCCCCCEEEEECC
NELVGALTWFEQSRKDRDRYLVSYDRLNRTIEQAVKKALPGALWWPSSPASGYLDFGDAW
CCEEEHHHHHHHHHCCHHHEEEEHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEECCCCC
HADGSGDMHYWSVWHENKSFDNYRSVRPRFCSEFGFQSYTSLPVIKTYAEEKDMNVASPV
CCCCCCCEEEEEEEECCCCCCHHHHCCHHHHHHCCCCCCCCCCCEEEHHHHCCCCHHHHH
MELHQKNAGGNERIAGTMFRYFRFPKDFPNFVYLSQIQQGLAIKTAVEYWRSLKPHCMGT
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEHHHHHCCCHHHHHHHHHHCCCCCEEEE
IYWQLNDTWPVASWSSLDYGGRWKAMHYLVKRFFQPVAVAAIPSEDGKTIRFSLVNDTLE
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCHH
DISIDLSISALTMKGERLHLKDVRAVCSPDAAVTAASIDVSDIPADTLLAWHFTASNGMG
HEEEEEEEEEEEECCCEEEHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCC
GEGHYVNGTYKALELEPSGLTVAHEYVEESGAIDINVTARGLALFVMIETETDGKYSDNA
CCCCEECCEEEEEEECCCCCCHHHHHHHHCCCEEEEEEECEEEEEEEEEECCCCCCCCCC
FDLAAGGSRRITFTPAHQLDRGALPEFRFYDLHSCQSAD
EEEECCCCEEEEECCHHHCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
TQQTPPSNIDLSGSWQLASVDGEIRTAIMLPGDVHTALHRAGLIPDPYFGRNEEKVQWV
CCCCCCCCCCCCCCEEEEEECCCEEEEEEECCHHHHHHHHCCCCCCCCCCCCHHHHHEE
AEREWAVERSFALPEVDGDWYLDIDYLDTVASVHVNGFLALEADNSFRRYRPDVSSMLKA
HHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHEEEEEEEEEECCCCHHHCCCCHHHHHHC
GDNVIRIVFASNIAVGAERQKKQPFYIPYSTGNSPIPDGNMLRKPQCHFGWDWNIAIAPF
CCCEEEEEEECCEEECCHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECC
GLYGTIALKKLETARIEHVVTRQTHNFDGSVDLTVTATLYSKGPSIAQVYFDLDGERVRL
CCEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCEEEEEEECCCCEEEE
DVGVHGETHVNHLFHIDNPRLWWPSGSGEQALYSLSVELPTDEVTKQIGLRTIELITTPD
EEECCCCCCCEEEEEECCCEEECCCCCCCCEEEEEEEECCHHHHHHHHCCEEEEEEECCC
ASGSRFAFKVNGREIFCRGANWIPADALFSLSSPEKTQDLLQSAVAANMNMIRVWGGGFY
CCCCEEEEEECCEEEEEECCCCCCHHHEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCC
EQDHFYDLCDRLGLMVWQDFMFACNLYPSTEDFLDNVAVEVDYQVRRLSSHPSIALWCGD
CCCHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHCCEEEEEEHHHEECCCCCCEEEEECC
NELVGALTWFEQSRKDRDRYLVSYDRLNRTIEQAVKKALPGALWWPSSPASGYLDFGDAW
CCEEEHHHHHHHHHCCHHHEEEEHHHHHHHHHHHHHHHCCCCEECCCCCCCCCEECCCCC
HADGSGDMHYWSVWHENKSFDNYRSVRPRFCSEFGFQSYTSLPVIKTYAEEKDMNVASPV
CCCCCCCEEEEEEEECCCCCCHHHHCCHHHHHHCCCCCCCCCCCEEEHHHHCCCCHHHHH
MELHQKNAGGNERIAGTMFRYFRFPKDFPNFVYLSQIQQGLAIKTAVEYWRSLKPHCMGT
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCEEHHHHHCCCHHHHHHHHHHCCCCCEEEE
IYWQLNDTWPVASWSSLDYGGRWKAMHYLVKRFFQPVAVAAIPSEDGKTIRFSLVNDTLE
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEEECCCHH
DISIDLSISALTMKGERLHLKDVRAVCSPDAAVTAASIDVSDIPADTLLAWHFTASNGMG
HEEEEEEEEEEEECCCEEEHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCC
GEGHYVNGTYKALELEPSGLTVAHEYVEESGAIDINVTARGLALFVMIETETDGKYSDNA
CCCCEECCEEEEEEECCCCCCHHHHHHHHCCCEEEEEEECEEEEEEEEEECCCCCCCCCC
FDLAAGGSRRITFTPAHQLDRGALPEFRFYDLHSCQSAD
EEEECCCCEEEEECCHHHCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]