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The map label for this gene is yghZ [H]

Identifier: 209549684

GI number: 209549684

Start: 2150384

End: 2151415

Strand: Reverse

Name: yghZ [H]

Synonym: Rleg2_2091

Alternate gene names: 209549684

Gene position: 2151415-2150384 (Counterclockwise)

Preceding gene: 209549685

Following gene: 209549683

Centisome position: 47.41

GC content: 61.72

Gene sequence:

>1032_bases
ATGAGCTGGCAACCAGCCGCAGACCGCTATTCGAAGATGAAATATAACCGTACGGGCCGGTCCGGCCTGAAGCTGCCGGC
CGTTTCCCTCGGCCTCTGGCATAATTTCGGCGGCGACACACCGCATGACCGCAAGATCGACATGTGCCGCACGGCCTTCG
ATCTCGGCATTACCCATTTCGACCTCGCCAACAATTATGGCCCGCCTCCCGGCAGCGCCGAAACCGCCTTCGGCGAGATC
CTGCGCACCGAATTTTCCGGGCTTCGCGACGAGCTGATCATCTCCTCCAAGGCTGGCTACGACATGTGGCCGGGGCCTTA
TGGCGAGTGGGGCAGCCGAAAATACGTGATCGCTTCCTGCGACCAGAGCCTGAAGCGCATGGGCCTCGACTATGTCGACA
TTTTCTATTCGCACCGCTTCGACCCGGAAACGCCGCTTGAAGAGACCTGCGGCGCGCTCGACCATATCGTCCGCTCCGGC
CGGGCGCTCTATGTCGGCATCTCCTCCTACAATTCGCAGCGTACGCGCGAAGCGGCCGCCATCCTCAAGGAGCTCGGCAC
GCCCTGCCTGATCCATCAGCCGAGTTATTCGATGCTCAACCGCTGGGTCGAGGATGACAGGCTGCTCGATGCGCTCGACG
AGGTCGGCATGGGCTCGATCGTGTTCTCGCCGCTTGCTCAGGGCATGCTGACGACGAAGTATCTCGGCGGTATCCCGGAC
GACAGCCGCGCGGCGCAAAACCATTTTCTGAAGCGCGACTTCATCCGTCCCTCTATCATCGACAATATCAAGAAGCTCAA
TGACATCGCCGAGAAGCGCGGCCAGACGCTGGCGCAGATGGCAATCGCCTGGGTGCTGCGCGGCGGACGCGTGACCTCGG
CGCTGATCGGTGCCAGCCGCTCATCGCAGATCGTCGATTGCGTCAAGGCGCTGGATAATCTGGAGTTCACGGCCGAGGAG
CTTGCGGAGATCGACGTCTACGCCCGCGAGGCGGATATCAATCTCTGGGCGAAGTCGGCGGAGCGGGAATAG

Upstream 100 bases:

>100_bases
GCCCCGTTTACGGGGAGAAGGTGGCGACAGCCGGATGAGGGGCAGCTCCTGCCAAGCACTGGCGGGACATCAATAGAGAT
ATTTTAGCAAGGAGAGTCTC

Downstream 100 bases:

>100_bases
GTAGGTCGAGCCGGAGTTTGGGGCGGCACGCTGCAACACCGCCCTCATCTCTGTGCTCGTCACAGAGATCCAGCCAGCCC
AAGTCCTTGGGCTGAATCGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSWQPAADRYSKMKYNRTGRSGLKLPAVSLGLWHNFGGDTPHDRKIDMCRTAFDLGITHFDLANNYGPPPGSAETAFGEI
LRTEFSGLRDELIISSKAGYDMWPGPYGEWGSRKYVIASCDQSLKRMGLDYVDIFYSHRFDPETPLEETCGALDHIVRSG
RALYVGISSYNSQRTREAAAILKELGTPCLIHQPSYSMLNRWVEDDRLLDALDEVGMGSIVFSPLAQGMLTTKYLGGIPD
DSRAAQNHFLKRDFIRPSIIDNIKKLNDIAEKRGQTLAQMAIAWVLRGGRVTSALIGASRSSQIVDCVKALDNLEFTAEE
LAEIDVYAREADINLWAKSAERE

Sequences:

>Translated_343_residues
MSWQPAADRYSKMKYNRTGRSGLKLPAVSLGLWHNFGGDTPHDRKIDMCRTAFDLGITHFDLANNYGPPPGSAETAFGEI
LRTEFSGLRDELIISSKAGYDMWPGPYGEWGSRKYVIASCDQSLKRMGLDYVDIFYSHRFDPETPLEETCGALDHIVRSG
RALYVGISSYNSQRTREAAAILKELGTPCLIHQPSYSMLNRWVEDDRLLDALDEVGMGSIVFSPLAQGMLTTKYLGGIPD
DSRAAQNHFLKRDFIRPSIIDNIKKLNDIAEKRGQTLAQMAIAWVLRGGRVTSALIGASRSSQIVDCVKALDNLEFTAEE
LAEIDVYAREADINLWAKSAERE
>Mature_342_residues
SWQPAADRYSKMKYNRTGRSGLKLPAVSLGLWHNFGGDTPHDRKIDMCRTAFDLGITHFDLANNYGPPPGSAETAFGEIL
RTEFSGLRDELIISSKAGYDMWPGPYGEWGSRKYVIASCDQSLKRMGLDYVDIFYSHRFDPETPLEETCGALDHIVRSGR
ALYVGISSYNSQRTREAAAILKELGTPCLIHQPSYSMLNRWVEDDRLLDALDEVGMGSIVFSPLAQGMLTTKYLGGIPDD
SRAAQNHFLKRDFIRPSIIDNIKKLNDIAEKRGQTLAQMAIAWVLRGGRVTSALIGASRSSQIVDCVKALDNLEFTAEEL
AEIDVYAREADINLWAKSAERE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=325, Percent_Identity=34.4615384615385, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4504825, Length=323, Percent_Identity=34.3653250773994, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI27436964, Length=337, Percent_Identity=31.1572700296736, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI27436962, Length=337, Percent_Identity=31.1572700296736, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI27436966, Length=329, Percent_Identity=31.306990881459, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI27436971, Length=326, Percent_Identity=32.8220858895706, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI41152114, Length=116, Percent_Identity=35.3448275862069, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=56.6473988439306, Blast_Score=416, Evalue=1e-118,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=30.4615384615385, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1788070, Length=320, Percent_Identity=27.1875, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=29.1907514450867, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788081, Length=307, Percent_Identity=26.3843648208469, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48994888, Length=295, Percent_Identity=23.728813559322, Blast_Score=68, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=342, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323998, Length=319, Percent_Identity=23.1974921630094, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=23.9043824701195, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=22.8956228956229, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640980, Length=326, Percent_Identity=25.7668711656442, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45549126, Length=326, Percent_Identity=25.7668711656442, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24646155, Length=309, Percent_Identity=25.2427184466019, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646159, Length=344, Percent_Identity=23.546511627907, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38280; Mature: 38149

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWQPAADRYSKMKYNRTGRSGLKLPAVSLGLWHNFGGDTPHDRKIDMCRTAFDLGITHF
CCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHE
DLANNYGPPPGSAETAFGEILRTEFSGLRDELIISSKAGYDMWPGPYGEWGSRKYVIASC
EHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCEEEEEHH
DQSLKRMGLDYVDIFYSHRFDPETPLEETCGALDHIVRSGRALYVGISSYNSQRTREAAA
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
ILKELGTPCLIHQPSYSMLNRWVEDDRLLDALDEVGMGSIVFSPLAQGMLTTKYLGGIPD
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
DSRAAQNHFLKRDFIRPSIIDNIKKLNDIAEKRGQTLAQMAIAWVLRGGRVTSALIGASR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
SSQIVDCVKALDNLEFTAEELAEIDVYAREADINLWAKSAERE
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCC
>Mature Secondary Structure 
SWQPAADRYSKMKYNRTGRSGLKLPAVSLGLWHNFGGDTPHDRKIDMCRTAFDLGITHF
CCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHE
DLANNYGPPPGSAETAFGEILRTEFSGLRDELIISSKAGYDMWPGPYGEWGSRKYVIASC
EHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCEEEEEHH
DQSLKRMGLDYVDIFYSHRFDPETPLEETCGALDHIVRSGRALYVGISSYNSQRTREAAA
HHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHH
ILKELGTPCLIHQPSYSMLNRWVEDDRLLDALDEVGMGSIVFSPLAQGMLTTKYLGGIPD
HHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
DSRAAQNHFLKRDFIRPSIIDNIKKLNDIAEKRGQTLAQMAIAWVLRGGRVTSALIGASR
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCC
SSQIVDCVKALDNLEFTAEELAEIDVYAREADINLWAKSAERE
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]