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The map label for this gene is ykvO [H]

Identifier: 209549680

GI number: 209549680

Start: 2145549

End: 2146286

Strand: Reverse

Name: ykvO [H]

Synonym: Rleg2_2087

Alternate gene names: 209549680

Gene position: 2146286-2145549 (Counterclockwise)

Preceding gene: 209549681

Following gene: 209549674

Centisome position: 47.3

GC content: 64.23

Gene sequence:

>738_bases
ATGACTGCAATCAAGATCGAAGGTGCGAAAGTGTTGATCGTCGGCGGCAGCTCGGGCATGGGTTTGGCGCTTGCCAGGCG
CCTGCTCGATGAGGGGGCGTTTGTGACGATCGCGGGGCGCAGTCAAGAGAGGCTTGCGGCAGCGTGCCGCCAGCTCGACG
ACGATCCGAAACTTGGAATCTACGCTGTCGATATATCGCGGGAGGAGGAGGTCGCGGCACTCTTTCGCATCGTCGGATCG
GTCGACCACATCGTCAGCACCGCCGCCGATATTGAAGGCGCCTATCAGTTGCTGCCGTCGATCGAGCTTGCCGCGGCGCA
ACGGGTGGTCGAGAGCAAGTTCTACGGCCCGCTGCTGCTGGCGAAATACGGCGCCGCCCATCTGCCGTCGTCAGGATCAA
TCACCTACACCTCGGGTGTCGCGGCCTATCGGCCGGCAGCGCGCGGATCGCTGGTCGCCGCCGTCAATGCGGCGCTTGAA
GGCCTGGTGAGGGCGCTCGCCGTCGAATTGGCACCGATCCGTATCAATGCCGTGTCGCCGGGATGGGTGGATACGCCGAT
CTGGAGCTTCGTTGCCGGGGACGCCAAGCAGGCAACGCTTGACGCGATGGCGCAGCGCCTGCCGGCCGGACGTGTCGGCC
AGCCGGAGGATATCGCCGATGCGATCCGCTTCCTGATCGGCAACGGTTTCACCACAGGCACTATCCTGCATGTCGAAGGC
GGGCATCGGCTGGTCTGA

Upstream 100 bases:

>100_bases
AACAGCATCATCGGGAAAGCCGATGATGCTATCGGTTTCTTCCGTTTTTCTTCCGCGCCGATCCGAGGCATCTGCTCTCC
CATGCAAATGGAGATGTGAG

Downstream 100 bases:

>100_bases
GGGGTAAAAATTCTTCGCTGGCCGATTGCATCAGGAGGGCGAGCGCCGGCGGCTGCACGCGCCGGCGCCGCCACATCATC
ACAAGCGAAGCGGTGGGCGG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MTAIKIEGAKVLIVGGSSGMGLALARRLLDEGAFVTIAGRSQERLAAACRQLDDDPKLGIYAVDISREEEVAALFRIVGS
VDHIVSTAADIEGAYQLLPSIELAAAQRVVESKFYGPLLLAKYGAAHLPSSGSITYTSGVAAYRPAARGSLVAAVNAALE
GLVRALAVELAPIRINAVSPGWVDTPIWSFVAGDAKQATLDAMAQRLPAGRVGQPEDIADAIRFLIGNGFTTGTILHVEG
GHRLV

Sequences:

>Translated_245_residues
MTAIKIEGAKVLIVGGSSGMGLALARRLLDEGAFVTIAGRSQERLAAACRQLDDDPKLGIYAVDISREEEVAALFRIVGS
VDHIVSTAADIEGAYQLLPSIELAAAQRVVESKFYGPLLLAKYGAAHLPSSGSITYTSGVAAYRPAARGSLVAAVNAALE
GLVRALAVELAPIRINAVSPGWVDTPIWSFVAGDAKQATLDAMAQRLPAGRVGQPEDIADAIRFLIGNGFTTGTILHVEG
GHRLV
>Mature_244_residues
TAIKIEGAKVLIVGGSSGMGLALARRLLDEGAFVTIAGRSQERLAAACRQLDDDPKLGIYAVDISREEEVAALFRIVGSV
DHIVSTAADIEGAYQLLPSIELAAAQRVVESKFYGPLLLAKYGAAHLPSSGSITYTSGVAAYRPAARGSLVAAVNAALEG
LVRALAVELAPIRINAVSPGWVDTPIWSFVAGDAKQATLDAMAQRLPAGRVGQPEDIADAIRFLIGNGFTTGTILHVEGG
HRLV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=28.099173553719, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=28.4090909090909, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=29.7959183673469, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI5031737, Length=229, Percent_Identity=29.2576419213974, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=26.9709543568465, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=31.0344827586207, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=31.3829787234043, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI126723750, Length=243, Percent_Identity=26.7489711934156, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=30.1652892561983, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=28.6290322580645, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=28.4, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=27.843137254902, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=29.5275590551181, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=28.4615384615385, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=26.6393442622951, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=28.2527881040892, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=28.8973384030418, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=29.718875502008, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=27.4436090225564, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=241, Percent_Identity=29.4605809128631, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=28.6821705426357, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=27.0676691729323, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=27.0676691729323, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=237, Percent_Identity=29.1139240506329, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=26.7782426778243, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=266, Percent_Identity=25.9398496240602, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=30.4878048780488, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=26.5873015873016, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=26.8, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737361, Length=258, Percent_Identity=26.7441860465116, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25555; Mature: 25423

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAIKIEGAKVLIVGGSSGMGLALARRLLDEGAFVTIAGRSQERLAAACRQLDDDPKLGI
CCEEEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCEE
YAVDISREEEVAALFRIVGSVDHIVSTAADIEGAYQLLPSIELAAAQRVVESKFYGPLLL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
AKYGAAHLPSSGSITYTSGVAAYRPAARGSLVAAVNAALEGLVRALAVELAPIRINAVSP
HHCCCCCCCCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GWVDTPIWSFVAGDAKQATLDAMAQRLPAGRVGQPEDIADAIRFLIGNGFTTGTILHVEG
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECC
GHRLV
CCCCC
>Mature Secondary Structure 
TAIKIEGAKVLIVGGSSGMGLALARRLLDEGAFVTIAGRSQERLAAACRQLDDDPKLGI
CEEEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCCCEE
YAVDISREEEVAALFRIVGSVDHIVSTAADIEGAYQLLPSIELAAAQRVVESKFYGPLLL
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHH
AKYGAAHLPSSGSITYTSGVAAYRPAARGSLVAAVNAALEGLVRALAVELAPIRINAVSP
HHCCCCCCCCCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GWVDTPIWSFVAGDAKQATLDAMAQRLPAGRVGQPEDIADAIRFLIGNGFTTGTILHVEG
CCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECC
GHRLV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]