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The map label for this gene is ywqM [H]

Identifier: 209549679

GI number: 209549679

Start: 2144663

End: 2145586

Strand: Direct

Name: ywqM [H]

Synonym: Rleg2_2086

Alternate gene names: 209549679

Gene position: 2144663-2145586 (Clockwise)

Preceding gene: 209549678

Following gene: 209549692

Centisome position: 47.26

GC content: 64.18

Gene sequence:

>924_bases
ATGAATCCACGACAGTTGAAGACATTCCTTGCGGTGATCCGGCATAAAAATCTCACCCGCGCCGCCGCTGAGGTCAACCT
TGCCCAATCGAGCCTCAGCGACCAGATACAGGCCCTGGAGGAAGAGCTTGGCGTGGAACTCTTTCTCCGCTCCCGCCAGG
GTGTCGCCCTAACGCCGGCGGGTGCGGCGCTAAAGGCCTATGCGGAGGAAATCCTGGCGCTGAATGACGAGGCAAAGGCC
GCCGTCTATGCTGCAGCCGGCAGAAGCGAGCAGTCCATCATCCTGGGCACGCTCGAAACCATCGCCGCCGAAAGGTTGGC
GCCCTGGCTCTCTCTCTTCCGCAGGCAGAATCCCGGCCTCGGTCTCAAACTCAAAGTCGGTGGCAGCGGCGAGCTGCGTG
CGCAATTGCAGCACGGTTCGATCGACGTCGCCTTCACCTTCGATCGCGGTGAGCAGGACGAGCGCGTCGCGACGCGCCGC
ATCTCCATCGAACCGCTGGTGTTGATCACGGGCCGCGATTCGCTGACCTGTAGACCCGAGAGCCTCGCGGCGCTGAGCGC
CATGCCCTTCGTCACGACCGAAACCGGCTGCATCTATCGCCACCTCTTCGACACCGCTTTTGCCGAAGCAGGCCTGCCGG
CACCGCCCATCGTCGCGCAAGCCGATAGCATCGCGACGATCATCAAGCTTGTCGCATCCGGCCCCGGTTACGGCCTCGTC
CCGCGTCTTGCAATCAGCCCGGCCGCTGCGCGCAGCGATGTCGTCGAATTGCCGTGGCCGGGCGAACCGCCCACCGCTTC
GCTTGTGATGATGTGGCGGCGCCGGCGCGTGCAGCCGCCGGCGCTCGCCCTCCTGATGCAATCGGCCAGCGAAGAATTTT
TACCCCTCAGACCAGCCGATGCCCGCCTTCGACATGCAGGATAG

Upstream 100 bases:

>100_bases
ACAAACGGCCCCTTCGTCGCCAAAATGCTCCTGCGTTGCAGCAGGTTCCGCTTTGTTGATATCCTGCGTCAAGGCGCCTG
CGCGCCCAGCGGAGCTTGAG

Downstream 100 bases:

>100_bases
TGCCTGTGGTGAAACCGTTGCCGATCAGGAAGCGGATCGCATCGGCGATATCCTCCGGCTGGCCGACACGTCCGGCCGGC
AGGCGCTGCGCCATCGCGTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNPRQLKTFLAVIRHKNLTRAAAEVNLAQSSLSDQIQALEEELGVELFLRSRQGVALTPAGAALKAYAEEILALNDEAKA
AVYAAAGRSEQSIILGTLETIAAERLAPWLSLFRRQNPGLGLKLKVGGSGELRAQLQHGSIDVAFTFDRGEQDERVATRR
ISIEPLVLITGRDSLTCRPESLAALSAMPFVTTETGCIYRHLFDTAFAEAGLPAPPIVAQADSIATIIKLVASGPGYGLV
PRLAISPAAARSDVVELPWPGEPPTASLVMMWRRRRVQPPALALLMQSASEEFLPLRPADARLRHAG

Sequences:

>Translated_307_residues
MNPRQLKTFLAVIRHKNLTRAAAEVNLAQSSLSDQIQALEEELGVELFLRSRQGVALTPAGAALKAYAEEILALNDEAKA
AVYAAAGRSEQSIILGTLETIAAERLAPWLSLFRRQNPGLGLKLKVGGSGELRAQLQHGSIDVAFTFDRGEQDERVATRR
ISIEPLVLITGRDSLTCRPESLAALSAMPFVTTETGCIYRHLFDTAFAEAGLPAPPIVAQADSIATIIKLVASGPGYGLV
PRLAISPAAARSDVVELPWPGEPPTASLVMMWRRRRVQPPALALLMQSASEEFLPLRPADARLRHAG
>Mature_307_residues
MNPRQLKTFLAVIRHKNLTRAAAEVNLAQSSLSDQIQALEEELGVELFLRSRQGVALTPAGAALKAYAEEILALNDEAKA
AVYAAAGRSEQSIILGTLETIAAERLAPWLSLFRRQNPGLGLKLKVGGSGELRAQLQHGSIDVAFTFDRGEQDERVATRR
ISIEPLVLITGRDSLTCRPESLAALSAMPFVTTETGCIYRHLFDTAFAEAGLPAPPIVAQADSIATIIKLVASGPGYGLV
PRLAISPAAARSDVVELPWPGEPPTASLVMMWRRRRVQPPALALLMQSASEEFLPLRPADARLRHAG

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787806, Length=277, Percent_Identity=30.6859205776173, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI87082132, Length=295, Percent_Identity=23.3898305084746, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790399, Length=281, Percent_Identity=28.4697508896797, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790208, Length=290, Percent_Identity=25.8620689655172, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787879, Length=293, Percent_Identity=30.0341296928328, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788887, Length=286, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=28.3950617283951, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787530, Length=261, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=30.7377049180328, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=28.6274509803922, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787601, Length=297, Percent_Identity=24.9158249158249, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994962, Length=157, Percent_Identity=33.7579617834395, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789506, Length=296, Percent_Identity=24.3243243243243, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=244, Percent_Identity=26.2295081967213, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788706, Length=152, Percent_Identity=30.9210526315789, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081904, Length=267, Percent_Identity=25.8426966292135, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI2367136, Length=303, Percent_Identity=25.0825082508251, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789173, Length=183, Percent_Identity=28.9617486338798, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790262, Length=248, Percent_Identity=24.1935483870968, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33066; Mature: 33066

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRQLKTFLAVIRHKNLTRAAAEVNLAQSSLSDQIQALEEELGVELFLRSRQGVALTPA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCC
GAALKAYAEEILALNDEAKAAVYAAAGRSEQSIILGTLETIAAERLAPWLSLFRRQNPGL
CHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
GLKLKVGGSGELRAQLQHGSIDVAFTFDRGEQDERVATRRISIEPLVLITGRDSLTCRPE
EEEEEECCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHEECCCEEEEEECCCCCEECHH
SLAALSAMPFVTTETGCIYRHLFDTAFAEAGLPAPPIVAQADSIATIIKLVASGPGYGLV
HHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHHHHCCCCCCCC
PRLAISPAAARSDVVELPWPGEPPTASLVMMWRRRRVQPPALALLMQSASEEFLPLRPAD
CHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
ARLRHAG
CHHCCCC
>Mature Secondary Structure
MNPRQLKTFLAVIRHKNLTRAAAEVNLAQSSLSDQIQALEEELGVELFLRSRQGVALTPA
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCC
GAALKAYAEEILALNDEAKAAVYAAAGRSEQSIILGTLETIAAERLAPWLSLFRRQNPGL
CHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
GLKLKVGGSGELRAQLQHGSIDVAFTFDRGEQDERVATRRISIEPLVLITGRDSLTCRPE
EEEEEECCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHEECCCEEEEEECCCCCEECHH
SLAALSAMPFVTTETGCIYRHLFDTAFAEAGLPAPPIVAQADSIATIIKLVASGPGYGLV
HHHHHHHCCCEECCCCHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHHHHHHHCCCCCCCC
PRLAISPAAARSDVVELPWPGEPPTASLVMMWRRRRVQPPALALLMQSASEEFLPLRPAD
CHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCC
ARLRHAG
CHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]