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The map label for this gene is cobT [H]

Identifier: 209549674

GI number: 209549674

Start: 2141006

End: 2142022

Strand: Reverse

Name: cobT [H]

Synonym: Rleg2_2081

Alternate gene names: 209549674

Gene position: 2142022-2141006 (Counterclockwise)

Preceding gene: 209549680

Following gene: 209549673

Centisome position: 47.2

GC content: 66.37

Gene sequence:

>1017_bases
ATGAGCGTTTCAGGCCTGCCGTTCGACGATTTCCGTACCCTGCTCCGCGACCTGCCGGGCCCGGATGCCCGTGCGCTGGT
GACCGCACGCGAACGTGACGCGCAACTGACCAAGCCGCCGGGCGCGCTCGGACGGCTTGAAGAAATCGCATTCTGGCTTG
CCGCCTGGACGGGCCGCACCCCTGCCGTCAACCGGCCGCTGGTGGCGATCTTCGCCGGCAATCACGGCGTCACCAGGCAG
GGAATCACGCCCTTTCCGCCGGCCGTGACACAGCAGATGGTCGAGAATTTTGCCGCCGGCGGCGCTGCGATCAATCAGAT
CTGCGTCGCTTATGATCTCGGGCTGAAGGTCTTCGATCTGGCGCTCGATTATCCCACCGGCGACATTACCGAGGAGGCAG
CGCTTTCCGAGCGCGATTGTGCCGCGACCATGGCCTTCGGCATGGAGGCGATCGCCGGCGGCACCGACTTGCTCTGCATC
GGCGAAATGGGCATCGGCAATACGACGATTGCCGCGGCGATCAACTATGCGCTCTATGGCGGTTCGGCGCGGGACTGGGT
CGGACCCGGCACCGGTTCGGAAGGCGAGATGCTGGAGCGCAAGATCGCGGCGGTGGAAAAGGCCGTGGAGCTCCACGGCG
ATCATCTCGACGATCCGCTGGAAATCATGCGCCGGCTCGGCGGCCGCGAGATTGCGGCGATGGCCGGCGCCATCCTTGCC
GCCCGCATGGAGCGTATCCCGGTGCTGATTGACGGTTACGTCGCAACCGCGGCGGCGGCGATCCTCAAAGCCGCCAATCC
ATCCGCGCTCGACCATTGCCTGATCGGCCATGTTTCCGCCGAGCCCGGACATCTGCGCGCGATCGAGATGCTCGGCAAGA
CGCCGCTTCTGGCGCTTGGCATGCGGCTCGGCGAAGGGACCGGGGCAGCGCTCGCCGCCGGCATCGTCAAAGCCGCCGCC
GCCTGCCATTCCGGCATGGCGACCTTTGCCCAGGCCGGTGTGACCAACAAAGACTGA

Upstream 100 bases:

>100_bases
TTTAAGAGAGTTGCGACCCGCAAAGAAGCTGATTTGCTCGACGCAAACAAGTGGTTTGCGTGAAAACAAGAATACCCGGA
TTCATAGGAAAACCGCACAG

Downstream 100 bases:

>100_bases
TGCCGCGGTCGGCGCCGCCTAAAGCGCGTCGCGTCAAACTCGATTCATGCGACGCGCTTTAGCTCTTTGTTTTTACGCAT
GTCGTTGCCGCACAACCGCT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSVSGLPFDDFRTLLRDLPGPDARALVTARERDAQLTKPPGALGRLEEIAFWLAAWTGRTPAVNRPLVAIFAGNHGVTRQ
GITPFPPAVTQQMVENFAAGGAAINQICVAYDLGLKVFDLALDYPTGDITEEAALSERDCAATMAFGMEAIAGGTDLLCI
GEMGIGNTTIAAAINYALYGGSARDWVGPGTGSEGEMLERKIAAVEKAVELHGDHLDDPLEIMRRLGGREIAAMAGAILA
ARMERIPVLIDGYVATAAAAILKAANPSALDHCLIGHVSAEPGHLRAIEMLGKTPLLALGMRLGEGTGAALAAGIVKAAA
ACHSGMATFAQAGVTNKD

Sequences:

>Translated_338_residues
MSVSGLPFDDFRTLLRDLPGPDARALVTARERDAQLTKPPGALGRLEEIAFWLAAWTGRTPAVNRPLVAIFAGNHGVTRQ
GITPFPPAVTQQMVENFAAGGAAINQICVAYDLGLKVFDLALDYPTGDITEEAALSERDCAATMAFGMEAIAGGTDLLCI
GEMGIGNTTIAAAINYALYGGSARDWVGPGTGSEGEMLERKIAAVEKAVELHGDHLDDPLEIMRRLGGREIAAMAGAILA
ARMERIPVLIDGYVATAAAAILKAANPSALDHCLIGHVSAEPGHLRAIEMLGKTPLLALGMRLGEGTGAALAAGIVKAAA
ACHSGMATFAQAGVTNKD
>Mature_337_residues
SVSGLPFDDFRTLLRDLPGPDARALVTARERDAQLTKPPGALGRLEEIAFWLAAWTGRTPAVNRPLVAIFAGNHGVTRQG
ITPFPPAVTQQMVENFAAGGAAINQICVAYDLGLKVFDLALDYPTGDITEEAALSERDCAATMAFGMEAIAGGTDLLCIG
EMGIGNTTIAAAINYALYGGSARDWVGPGTGSEGEMLERKIAAVEKAVELHGDHLDDPLEIMRRLGGREIAAMAGAILAA
RMERIPVLIDGYVATAAAAILKAANPSALDHCLIGHVSAEPGHLRAIEMLGKTPLLALGMRLGEGTGAALAAGIVKAAAA
CHSGMATFAQAGVTNKD

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=342, Percent_Identity=30.7017543859649, Blast_Score=147, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35049; Mature: 34918

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSGLPFDDFRTLLRDLPGPDARALVTARERDAQLTKPPGALGRLEEIAFWLAAWTGRT
CCCCCCCHHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PAVNRPLVAIFAGNHGVTRQGITPFPPAVTQQMVENFAAGGAAINQICVAYDLGLKVFDL
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
ALDYPTGDITEEAALSERDCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAINYALYG
EECCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCC
GSARDWVGPGTGSEGEMLERKIAAVEKAVELHGDHLDDPLEIMRRLGGREIAAMAGAILA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHH
ARMERIPVLIDGYVATAAAAILKAANPSALDHCLIGHVSAEPGHLRAIEMLGKTPLLALG
HHHHHCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHH
MRLGEGTGAALAAGIVKAAAACHSGMATFAQAGVTNKD
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVSGLPFDDFRTLLRDLPGPDARALVTARERDAQLTKPPGALGRLEEIAFWLAAWTGRT
CCCCCCHHHHHHHHHHCCCCCCCEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
PAVNRPLVAIFAGNHGVTRQGITPFPPAVTQQMVENFAAGGAAINQICVAYDLGLKVFDL
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEE
ALDYPTGDITEEAALSERDCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAINYALYG
EECCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCC
GSARDWVGPGTGSEGEMLERKIAAVEKAVELHGDHLDDPLEIMRRLGGREIAAMAGAILA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHH
ARMERIPVLIDGYVATAAAAILKAANPSALDHCLIGHVSAEPGHLRAIEMLGKTPLLALG
HHHHHCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHH
MRLGEGTGAALAAGIVKAAAACHSGMATFAQAGVTNKD
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA