Click here to switch to the map view.

The map label for this gene is ycjZ [C]

Identifier: 209549638

GI number: 209549638

Start: 2108825

End: 2109718

Strand: Reverse

Name: ycjZ [C]

Synonym: Rleg2_2045

Alternate gene names: 209549638

Gene position: 2109718-2108825 (Counterclockwise)

Preceding gene: 209549641

Following gene: 209549637

Centisome position: 46.49

GC content: 62.08

Gene sequence:

>894_bases
ATGCCGCGTCCTGCCGTCAATGACCTGATCGCCTTCCTTGCCGTTGCCCGTGCAAAAAGCTTCACGAAGGCGGCGGCGAA
GCTCGGTGTGTCGCAATCGGCGCTCAGCCATACGATCCGCGGGCTCGAGGAGCGGCTTGGCTTGCGATTGCTGACACGCA
CGACGCGTAGCGTCTCGCCGACGGAGGCGGGTGAACGCCTGCTTCTCACCATCGGCCCGCGGCTAGATGAGATCGAGACT
GAGCTCGTCGCCTTGAGCGCCTTTCGGGAAAAGCCGGCCGGCAGCATTCGCATCAATGCCGGCGAGCATGCGGCGGATGC
CGTCCTCTGGCCCGCCTTGGAAAAGCTTCTGCCTGATTATCCAGATATCAACGTCGAGATCATCGTCGATTACGGCCTGA
CCGACATCGTCGCCGAACGCTACGATGCGGGTGTGCGGCTGGGGGAACAGGTGGCCAAGGATATGATCGCGGTCCGCATC
GGTCCCGACATGCGCATGGCTGTGGTCGGCGCTCCCGGCTATTTCGAAAGACGGACGAAGCCGCTGACGCCGCAGGATCT
CACCGATCACAACTGCATCAATTTGCGCCTGCCGACTTATGGCGGCGTCTATGCCTGGGAGTTCGAGCGGGAGGGGCACG
AGTTGAAGGTTCGCGTCGAGGGACAATTGATCTTCAACAATATTGCACTCAGGCTGAACGCGGCGCTCGCCGGGGCGGGG
CTTGCATATCTGCCTGAAGATGCCGTGCAGGGGCATCTTGCCGAGGGACGGCTGGTGCGCGTGCTCGAAGACTGGTGTCC
GCCGTTTCCCGGCTATCATCTCTATTATCCGAGCCGGCGGCACGCCTCAGCGGCCTTCGTCCTTGTCGTTGATGCGCTTC
GCTATCGAGGATAG

Upstream 100 bases:

>100_bases
CGGCGGATGTCTTCGTCCTCAGATGACAGGATATTTAGCGCGTGCCTTTGGCCGTGATTAGATGGTAGTTCTGGCACGGA
CTTATGAGAAGGTTTCATAA

Downstream 100 bases:

>100_bases
CGGCCGACATTCTCAGATCCCGTCAACGAGGGGGCATCCACGCCAGCACTTGTTAACTCCGGCGGACACTTGGCGGAGTG
AAAACATGCTGCGTCGGCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MPRPAVNDLIAFLAVARAKSFTKAAAKLGVSQSALSHTIRGLEERLGLRLLTRTTRSVSPTEAGERLLLTIGPRLDEIET
ELVALSAFREKPAGSIRINAGEHAADAVLWPALEKLLPDYPDINVEIIVDYGLTDIVAERYDAGVRLGEQVAKDMIAVRI
GPDMRMAVVGAPGYFERRTKPLTPQDLTDHNCINLRLPTYGGVYAWEFEREGHELKVRVEGQLIFNNIALRLNAALAGAG
LAYLPEDAVQGHLAEGRLVRVLEDWCPPFPGYHLYYPSRRHASAAFVLVVDALRYRG

Sequences:

>Translated_297_residues
MPRPAVNDLIAFLAVARAKSFTKAAAKLGVSQSALSHTIRGLEERLGLRLLTRTTRSVSPTEAGERLLLTIGPRLDEIET
ELVALSAFREKPAGSIRINAGEHAADAVLWPALEKLLPDYPDINVEIIVDYGLTDIVAERYDAGVRLGEQVAKDMIAVRI
GPDMRMAVVGAPGYFERRTKPLTPQDLTDHNCINLRLPTYGGVYAWEFEREGHELKVRVEGQLIFNNIALRLNAALAGAG
LAYLPEDAVQGHLAEGRLVRVLEDWCPPFPGYHLYYPSRRHASAAFVLVVDALRYRG
>Mature_296_residues
PRPAVNDLIAFLAVARAKSFTKAAAKLGVSQSALSHTIRGLEERLGLRLLTRTTRSVSPTEAGERLLLTIGPRLDEIETE
LVALSAFREKPAGSIRINAGEHAADAVLWPALEKLLPDYPDINVEIIVDYGLTDIVAERYDAGVRLGEQVAKDMIAVRIG
PDMRMAVVGAPGYFERRTKPLTPQDLTDHNCINLRLPTYGGVYAWEFEREGHELKVRVEGQLIFNNIALRLNAALAGAGL
AYLPEDAVQGHLAEGRLVRVLEDWCPPFPGYHLYYPSRRHASAAFVLVVDALRYRG

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=297, Percent_Identity=54.2087542087542, Blast_Score=343, Evalue=7e-96,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=42.8082191780822, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1786401, Length=274, Percent_Identity=28.1021897810219, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789639, Length=268, Percent_Identity=30.9701492537313, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=31.0580204778157, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789440, Length=264, Percent_Identity=27.6515151515151, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693193, Length=284, Percent_Identity=29.9295774647887, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1789173, Length=269, Percent_Identity=30.1115241635688, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786448, Length=294, Percent_Identity=25.5102040816327, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788706, Length=259, Percent_Identity=25.4826254826255, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=35, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32756; Mature: 32625

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPAVNDLIAFLAVARAKSFTKAAAKLGVSQSALSHTIRGLEERLGLRLLTRTTRSVSP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCC
TEAGERLLLTIGPRLDEIETELVALSAFREKPAGSIRINAGEHAADAVLWPALEKLLPDY
CCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCC
PDINVEIIVDYGLTDIVAERYDAGVRLGEQVAKDMIAVRIGPDMRMAVVGAPGYFERRTK
CCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHCCC
PLTPQDLTDHNCINLRLPTYGGVYAWEFEREGHELKVRVEGQLIFNNIALRLNAALAGAG
CCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEEEEECEEEEEEEEEEEEEHHHCCC
LAYLPEDAVQGHLAEGRLVRVLEDWCPPFPGYHLYYPSRRHASAAFVLVVDALRYRG
CEECCCHHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRPAVNDLIAFLAVARAKSFTKAAAKLGVSQSALSHTIRGLEERLGLRLLTRTTRSVSP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCC
TEAGERLLLTIGPRLDEIETELVALSAFREKPAGSIRINAGEHAADAVLWPALEKLLPDY
CCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCC
PDINVEIIVDYGLTDIVAERYDAGVRLGEQVAKDMIAVRIGPDMRMAVVGAPGYFERRTK
CCCEEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHCCC
PLTPQDLTDHNCINLRLPTYGGVYAWEFEREGHELKVRVEGQLIFNNIALRLNAALAGAG
CCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEEEEECEEEEEEEEEEEEEHHHCCC
LAYLPEDAVQGHLAEGRLVRVLEDWCPPFPGYHLYYPSRRHASAAFVLVVDALRYRG
CEECCCHHHCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]