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The map label for this gene is glsA [H]

Identifier: 209549540

GI number: 209549540

Start: 1989599

End: 1990528

Strand: Reverse

Name: glsA [H]

Synonym: Rleg2_1946

Alternate gene names: 209549540

Gene position: 1990528-1989599 (Counterclockwise)

Preceding gene: 209549541

Following gene: 209549539

Centisome position: 43.86

GC content: 63.55

Gene sequence:

>930_bases
ATGGCGGATCTGCAGGCAATCCTCGATAGTATCCATACCGATATCCTCCCGCGCATCGGCGAGGGCAAGGTCGCCGACTA
TATTCCCGAGCTTGCCAAGGTCGATCCACGGCAGTTCGGCATGGCGATCGTCACCGTCGACGGCAAGGTCTATCGTGTCG
GCGATGCCGACATTGCCTTCTCGATCCAGAGCATCTCCAAGGTCTTTATGCTGACCTTGGCGCTCGGCAAGGTCGGCGAG
AGCCTCTGGAAGCGCGTCGGGCGAGAACCATCCGGATCGGCCTTCAATTCCATCGTCCAGCTCGAGCACGAGGGCGGCAT
CCCGCGCAATCCCTTCATCAATGCCGGCGCGATCGCCGTTTCCGACGTCGTCATGGCCGGCCATGCGCCGCGTGAGGCGA
TCGGCGAATTGCTGCGCTTCGTGCGTTATCTCGCCGATGACGAATCGATCACCATCGACGACAAGGTGGCGCGCTCGGAA
ACGCAGACAGGATACCGCAATGTCGCGCTTGCCAATTTCATGCGCGCCTACCGCAATCTCGACCATCCCGTCGACCATGT
GCTCGGCGTCTATTTCCATCAATGCGCGCTGTCGATGAGCTGCGAACAGCTGGCCCGCGCCGGGCTGTTCCTGGCGGCCC
GCGGCAGCAATCCGATGACCGGCCATTCGGTGGTCTCGCCGAAGCGGGCGCGGCGCATCAATGCGCTGATGCTGACCTGC
GGCCATTACGACGGCTCGGGCGATTTCGCCTATCATGTCGGCCTGCCCGGCAAGAGCGGTGTAGGCGGCGGCATCTTCGC
GGTTGCGCCGGGCATCGCCTCGATCGCCGTCTGGTCGCCGGGCTTGAACAAGGTCGGCAATTCGCAGCTCGGCGCCGTGG
CGCTGGAAATGCTGGCGGCGCGCACCGGCTGGTCGGTTTTCGGCGATTGA

Upstream 100 bases:

>100_bases
CTGGTCGTCGAATTCTATTCGCGTTAATAAGAACCAGGCGTTTTCGCTTATGGAAAAGCCGCTCTTTCGGGCGGCTTTTT
TTGTTATCCGGAGAGAAGCG

Downstream 100 bases:

>100_bases
CGCTGTGTTGGCGAACTCGTTTCTGCTAAGGCAGACAGACCTCGATAGGACGACGCAATGAATATCGCAGCCAATATTGC
GGATGATCTGGAAAGCGGCG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MADLQAILDSIHTDILPRIGEGKVADYIPELAKVDPRQFGMAIVTVDGKVYRVGDADIAFSIQSISKVFMLTLALGKVGE
SLWKRVGREPSGSAFNSIVQLEHEGGIPRNPFINAGAIAVSDVVMAGHAPREAIGELLRFVRYLADDESITIDDKVARSE
TQTGYRNVALANFMRAYRNLDHPVDHVLGVYFHQCALSMSCEQLARAGLFLAARGSNPMTGHSVVSPKRARRINALMLTC
GHYDGSGDFAYHVGLPGKSGVGGGIFAVAPGIASIAVWSPGLNKVGNSQLGAVALEMLAARTGWSVFGD

Sequences:

>Translated_309_residues
MADLQAILDSIHTDILPRIGEGKVADYIPELAKVDPRQFGMAIVTVDGKVYRVGDADIAFSIQSISKVFMLTLALGKVGE
SLWKRVGREPSGSAFNSIVQLEHEGGIPRNPFINAGAIAVSDVVMAGHAPREAIGELLRFVRYLADDESITIDDKVARSE
TQTGYRNVALANFMRAYRNLDHPVDHVLGVYFHQCALSMSCEQLARAGLFLAARGSNPMTGHSVVSPKRARRINALMLTC
GHYDGSGDFAYHVGLPGKSGVGGGIFAVAPGIASIAVWSPGLNKVGNSQLGAVALEMLAARTGWSVFGD
>Mature_308_residues
ADLQAILDSIHTDILPRIGEGKVADYIPELAKVDPRQFGMAIVTVDGKVYRVGDADIAFSIQSISKVFMLTLALGKVGES
LWKRVGREPSGSAFNSIVQLEHEGGIPRNPFINAGAIAVSDVVMAGHAPREAIGELLRFVRYLADDESITIDDKVARSET
QTGYRNVALANFMRAYRNLDHPVDHVLGVYFHQCALSMSCEQLARAGLFLAARGSNPMTGHSVVSPKRARRINALMLTCG
HYDGSGDFAYHVGLPGKSGVGGGIFAVAPGIASIAVWSPGLNKVGNSQLGAVALEMLAARTGWSVFGD

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=273, Percent_Identity=38.8278388278388, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI20336214, Length=296, Percent_Identity=36.8243243243243, Blast_Score=192, Evalue=5e-49,
Organism=Escherichia coli, GI1787804, Length=304, Percent_Identity=51.9736842105263, Blast_Score=293, Evalue=8e-81,
Organism=Escherichia coli, GI1786693, Length=305, Percent_Identity=40.655737704918, Blast_Score=199, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17507019, Length=291, Percent_Identity=37.8006872852234, Blast_Score=192, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI193204073, Length=286, Percent_Identity=37.4125874125874, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193204075, Length=288, Percent_Identity=37.1527777777778, Blast_Score=187, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17532727, Length=301, Percent_Identity=34.21926910299, Blast_Score=180, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24653162, Length=307, Percent_Identity=35.5048859934853, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI281363241, Length=307, Percent_Identity=35.5048859934853, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653166, Length=307, Percent_Identity=35.5048859934853, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653156, Length=307, Percent_Identity=35.5048859934853, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI116008307, Length=307, Percent_Identity=35.5048859934853, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653164, Length=307, Percent_Identity=35.5048859934853, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24653158, Length=307, Percent_Identity=35.5048859934853, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI281363239, Length=307, Percent_Identity=35.5048859934853, Blast_Score=189, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32977; Mature: 32846

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLQAILDSIHTDILPRIGEGKVADYIPELAKVDPRQFGMAIVTVDGKVYRVGDADIAF
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHCEEEEEECCEEEEECCCHHHH
SIQSISKVFMLTLALGKVGESLWKRVGREPSGSAFNSIVQLEHEGGIPRNPFINAGAIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECCCCCCCCCCCCCCCHHHH
SDVVMAGHAPREAIGELLRFVRYLADDESITIDDKVARSETQTGYRNVALANFMRAYRNL
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCHHHHHHHHHHHHHHCC
DHPVDHVLGVYFHQCALSMSCEQLARAGLFLAARGSNPMTGHSVVSPKRARRINALMLTC
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHEEEEEE
GHYDGSGDFAYHVGLPGKSGVGGGIFAVAPGIASIAVWSPGLNKVGNSQLGAVALEMLAA
CCCCCCCCEEEEECCCCCCCCCCCHHHHCCCHHEEEEECCCCCCCCCCHHHHHHHHHHHH
RTGWSVFGD
HCCCCCCCC
>Mature Secondary Structure 
ADLQAILDSIHTDILPRIGEGKVADYIPELAKVDPRQFGMAIVTVDGKVYRVGDADIAF
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHCEEEEEECCEEEEECCCHHHH
SIQSISKVFMLTLALGKVGESLWKRVGREPSGSAFNSIVQLEHEGGIPRNPFINAGAIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECCCCCCCCCCCCCCCHHHH
SDVVMAGHAPREAIGELLRFVRYLADDESITIDDKVARSETQTGYRNVALANFMRAYRNL
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHCCHHHHHHHHHHHHHHCC
DHPVDHVLGVYFHQCALSMSCEQLARAGLFLAARGSNPMTGHSVVSPKRARRINALMLTC
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHEEEEEE
GHYDGSGDFAYHVGLPGKSGVGGGIFAVAPGIASIAVWSPGLNKVGNSQLGAVALEMLAA
CCCCCCCCEEEEECCCCCCCCCCCHHHHCCCHHEEEEECCCCCCCCCCHHHHHHHHHHHH
RTGWSVFGD
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA