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The map label for this gene is nahR [H]

Identifier: 209549405

GI number: 209549405

Start: 1861071

End: 1861964

Strand: Direct

Name: nahR [H]

Synonym: Rleg2_1811

Alternate gene names: 209549405

Gene position: 1861071-1861964 (Clockwise)

Preceding gene: 209549403

Following gene: 209549406

Centisome position: 41.01

GC content: 68.01

Gene sequence:

>894_bases
ATGTCGACACCCGATCTCAACCTGCTCGTCACCCTGGATGTGCTGCTTGCCGAAGGCAGCGTTGCCCGCGCCGCCCACAG
GCTGCGGCTCAGCCCATCGGCCATGAGCCGGGCGCTGGCGCGACTGCGCGAGACAACGGGCGATCCGCTGTTGGTGCGCG
CCGGCCGCGGCCTCGTCCCCACGCCCCGGGCGCTTGAACTGCGCGAGCGGGTCGGCCGGATCGTCGAGGATGCGCAAGCG
GTGCTGCGCCCTGCCGAGGTGCTTGGTCTCAAACGCTTGGTCCGGACGTTCACGCTGCGCACCAGCGAAGGTTTCGCCGA
GACCTTCGGACCCGATCTGATCGCCCGCCTCGGTGGTGAAGCGCCCGGCGTGCGGCTGCGCTTCGTGCAGAAACCGGATA
AGGACAGCGCCCCGCTACGCGACGGAAGCGTCGACCTGGAAACCGGCGTCGTCGGCGAAACGATGGGACCGGAGGTGCGG
GCGCAGGCCTTGTTCCGCGACCGTTTCGTCGGTGTCGTGCGGACAGGGCATCCGCTCTGCCAAGGGGAGATCACGCCCGC
CCGGTATGCTGCCGGCCGGCACATCGCCGTCTCCCGGCGCGGGCTCGACAAGGGAAGGATCGATGAAGCCCTCGATGCGC
TCGGGCTCGAACGGCAGATTGCCACGATCGTCGGTGGATTTTCAACAGCGCTGGCGCTTGCCCGCGCCTCGGACCTGATC
GCCAGTGTTCCGGAACGGCACACAGGGGCATTGCGCCAGGGAATGCATAGTTTCCCCCTGCCCGTTCCGATCCCTGAGAT
CACGCTTTCCCTGCTCTGGCATCCAAGGATGGATGCCGATCCGGCCCATCGCTGGCTGCGCGGCTGCGTTCGGGAGGCCT
GCGCGGCAATTTGA

Upstream 100 bases:

>100_bases
CGCCGGCAAACATAGTCCTCCGCCCAATATGGCGGAACACGCAGCATTTGCATTCTATTCGTGCGTTGGACGCTATATGA
AGCCGTGTTATATCGGATGC

Downstream 100 bases:

>100_bases
TCACGAACGATCAATCGGATGGTCGTGGTTGACTATCCCGCGTCGACGTGATTTCCCGCCCGAGATCATCAGGCGAATTA
TGAGGTGGGAACATCATGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSTPDLNLLVTLDVLLAEGSVARAAHRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRALELRERVGRIVEDAQA
VLRPAEVLGLKRLVRTFTLRTSEGFAETFGPDLIARLGGEAPGVRLRFVQKPDKDSAPLRDGSVDLETGVVGETMGPEVR
AQALFRDRFVGVVRTGHPLCQGEITPARYAAGRHIAVSRRGLDKGRIDEALDALGLERQIATIVGGFSTALALARASDLI
ASVPERHTGALRQGMHSFPLPVPIPEITLSLLWHPRMDADPAHRWLRGCVREACAAI

Sequences:

>Translated_297_residues
MSTPDLNLLVTLDVLLAEGSVARAAHRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRALELRERVGRIVEDAQA
VLRPAEVLGLKRLVRTFTLRTSEGFAETFGPDLIARLGGEAPGVRLRFVQKPDKDSAPLRDGSVDLETGVVGETMGPEVR
AQALFRDRFVGVVRTGHPLCQGEITPARYAAGRHIAVSRRGLDKGRIDEALDALGLERQIATIVGGFSTALALARASDLI
ASVPERHTGALRQGMHSFPLPVPIPEITLSLLWHPRMDADPAHRWLRGCVREACAAI
>Mature_296_residues
STPDLNLLVTLDVLLAEGSVARAAHRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVPTPRALELRERVGRIVEDAQAV
LRPAEVLGLKRLVRTFTLRTSEGFAETFGPDLIARLGGEAPGVRLRFVQKPDKDSAPLRDGSVDLETGVVGETMGPEVRA
QALFRDRFVGVVRTGHPLCQGEITPARYAAGRHIAVSRRGLDKGRIDEALDALGLERQIATIVGGFSTALALARASDLIA
SVPERHTGALRQGMHSFPLPVPIPEITLSLLWHPRMDADPAHRWLRGCVREACAAI

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=309, Percent_Identity=27.1844660194175, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081684, Length=295, Percent_Identity=26.1016949152542, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI87081766, Length=298, Percent_Identity=24.496644295302, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32127; Mature: 31995

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPDLNLLVTLDVLLAEGSVARAAHRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVP
CCCCCCCCEEEHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
TPRALELRERVGRIVEDAQAVLRPAEVLGLKRLVRTFTLRTSEGFAETFGPDLIARLGGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHCCC
APGVRLRFVQKPDKDSAPLRDGSVDLETGVVGETMGPEVRAQALFRDRFVGVVRTGHPLC
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
QGEITPARYAAGRHIAVSRRGLDKGRIDEALDALGLERQIATIVGGFSTALALARASDLI
CCCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVPERHTGALRQGMHSFPLPVPIPEITLSLLWHPRMDADPAHRWLRGCVREACAAI
HHCCCHHHHHHHCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STPDLNLLVTLDVLLAEGSVARAAHRLRLSPSAMSRALARLRETTGDPLLVRAGRGLVP
CCCCCCCEEEHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCC
TPRALELRERVGRIVEDAQAVLRPAEVLGLKRLVRTFTLRTSEGFAETFGPDLIARLGGE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHCCC
APGVRLRFVQKPDKDSAPLRDGSVDLETGVVGETMGPEVRAQALFRDRFVGVVRTGHPLC
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
QGEITPARYAAGRHIAVSRRGLDKGRIDEALDALGLERQIATIVGGFSTALALARASDLI
CCCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASVPERHTGALRQGMHSFPLPVPIPEITLSLLWHPRMDADPAHRWLRGCVREACAAI
HHCCCHHHHHHHCCHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]