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The map label for this gene is adrA [H]

Identifier: 209549403

GI number: 209549403

Start: 1857508

End: 1858683

Strand: Direct

Name: adrA [H]

Synonym: Rleg2_1809

Alternate gene names: 209549403

Gene position: 1857508-1858683 (Clockwise)

Preceding gene: 209549402

Following gene: 209549405

Centisome position: 40.93

GC content: 57.82

Gene sequence:

>1176_bases
ATGGATCTTGCGACAGTCCTTCTTCTACACAAGTCTTCCTTCATCGTCGGAGCAATCTGCTTCTTCTACGTGAGATGGCG
CTCTGGAGCGACGCCAGGGCTTGGTGTACTCGCCGTCGGTTTTTCCTTGCTCGCGATCGCCTCGACGCTGGCAGGTTTGG
ACGAGCGTCTTCACATGTCCGATAATGCCAGGACATTCTGGAGTTTTTCGCTTGGCGCCAATGGTTACGGGCTGATGGCG
GTGGGTCTTTATGGCCTCAGCCGGCGTCACAGCTCCCTTCGAGACTGGTGGCCGATGCTCCTGCCTGTCACCCTCACGCT
CAGTGCGGCGATCACGCCGTGGTATGTGGACAACGGGCTCAGAGCATCCGTCTTCAACGGCAACGCCGCCATTCTGCTGG
CCTTGTCGGGGTTGGTGATCGCCCGCGACTTCTTTCAGGAGCGTCTTACCGCGCGGTTCGGTCTTTCCGCGGCCATTTTC
GTCGCGACGTCTCTTTCAGCGTTGGTCGTGCTCGGTTTCACCTTTCCGAACGATGCGCCTCTTCCGCCGCGCTACGCATT
CTTTTTGCTGATTATCTGTCATTTCGCGGTGGCTCTGTTCGTACTCGTGCTCGTGCAGGAAAGAGCCGAAGAGAAGCTTA
CCAGACTTGCGAATACCGATATGCTGACCGGCGTTCCCAATCGGCAGCATTTCTTCAGCTCGCTTCCCAAAAGCCTCGGG
CCCGGAGACGCATTCGTCCTGATCGATATCGACTTTTTCAAGAGCGTGAACGACCGGTTCGGACACGACAGAGGCGATAT
TGTTCTCGTGGATGTTGCTCGGACGATTGCTCGCAGCATTCCTCCGTCCAGCGTCTTCGGCCGGCTGGGCGGCGAAGAGT
TCAGCCTCTTCGTTCGCGGTGAAACAGAAGCCTCTGCTTTTGCGCTCGCGGAGCAGATACGTGAGGCCGTCAACACTTTG
GATCTCGTCTTCGAAGGAAAACAGGTATCCACTACCGTCAGCGCAGGCGTGGCGCTCTGGGAAGCGAACCTCACGGAACA
AGACATCCAGAAGCGGGCAGATCAAGCGCTTTACAGTGCCAAAAATAACGGCCGCAACAGGGTGGAATTGTTTACCGGCA
TCGGGTTGACCGACAGCTCCCCTGCACCCGAACGGCGACTGGCCCGCGCAGGCTGA

Upstream 100 bases:

>100_bases
AATAGCGATTGCTCCGTCGCATTGTCGCGCAGCGTTCATCGAAAAGTAGATTTTAGTCGCTATTCCGGCCCCGCTTCTCA
TCTCATATCGGGTTCCGGCA

Downstream 100 bases:

>100_bases
CAACAGCGGAGACCGGTCACGCTCAGACTGACTGGCACGTCATAGCGGAATGCCGGCAAATGCTACAGAGCACGTTGACG
CTGCCATCAAAGCTGCTAAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MDLATVLLLHKSSFIVGAICFFYVRWRSGATPGLGVLAVGFSLLAIASTLAGLDERLHMSDNARTFWSFSLGANGYGLMA
VGLYGLSRRHSSLRDWWPMLLPVTLTLSAAITPWYVDNGLRASVFNGNAAILLALSGLVIARDFFQERLTARFGLSAAIF
VATSLSALVVLGFTFPNDAPLPPRYAFFLLIICHFAVALFVLVLVQERAEEKLTRLANTDMLTGVPNRQHFFSSLPKSLG
PGDAFVLIDIDFFKSVNDRFGHDRGDIVLVDVARTIARSIPPSSVFGRLGGEEFSLFVRGETEASAFALAEQIREAVNTL
DLVFEGKQVSTTVSAGVALWEANLTEQDIQKRADQALYSAKNNGRNRVELFTGIGLTDSSPAPERRLARAG

Sequences:

>Translated_391_residues
MDLATVLLLHKSSFIVGAICFFYVRWRSGATPGLGVLAVGFSLLAIASTLAGLDERLHMSDNARTFWSFSLGANGYGLMA
VGLYGLSRRHSSLRDWWPMLLPVTLTLSAAITPWYVDNGLRASVFNGNAAILLALSGLVIARDFFQERLTARFGLSAAIF
VATSLSALVVLGFTFPNDAPLPPRYAFFLLIICHFAVALFVLVLVQERAEEKLTRLANTDMLTGVPNRQHFFSSLPKSLG
PGDAFVLIDIDFFKSVNDRFGHDRGDIVLVDVARTIARSIPPSSVFGRLGGEEFSLFVRGETEASAFALAEQIREAVNTL
DLVFEGKQVSTTVSAGVALWEANLTEQDIQKRADQALYSAKNNGRNRVELFTGIGLTDSSPAPERRLARAG
>Mature_391_residues
MDLATVLLLHKSSFIVGAICFFYVRWRSGATPGLGVLAVGFSLLAIASTLAGLDERLHMSDNARTFWSFSLGANGYGLMA
VGLYGLSRRHSSLRDWWPMLLPVTLTLSAAITPWYVDNGLRASVFNGNAAILLALSGLVIARDFFQERLTARFGLSAAIF
VATSLSALVVLGFTFPNDAPLPPRYAFFLLIICHFAVALFVLVLVQERAEEKLTRLANTDMLTGVPNRQHFFSSLPKSLG
PGDAFVLIDIDFFKSVNDRFGHDRGDIVLVDVARTIARSIPPSSVFGRLGGEEFSLFVRGETEASAFALAEQIREAVNTL
DLVFEGKQVSTTVSAGVALWEANLTEQDIQKRADQALYSAKNNGRNRVELFTGIGLTDSSPAPERRLARAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=222, Percent_Identity=33.7837837837838, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787262, Length=270, Percent_Identity=30, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081881, Length=169, Percent_Identity=38.4615384615385, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787802, Length=159, Percent_Identity=36.4779874213836, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788381, Length=167, Percent_Identity=35.3293413173653, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787541, Length=174, Percent_Identity=34.4827586206897, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI145693134, Length=180, Percent_Identity=29.4444444444444, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=34.5911949685535, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788085, Length=181, Percent_Identity=32.0441988950276, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=33.125, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081974, Length=178, Percent_Identity=29.7752808988764, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI87081977, Length=161, Percent_Identity=31.6770186335404, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787056, Length=163, Percent_Identity=30.6748466257669, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788956, Length=164, Percent_Identity=32.3170731707317, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 42567; Mature: 42567

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLATVLLLHKSSFIVGAICFFYVRWRSGATPGLGVLAVGFSLLAIASTLAGLDERLHMS
CCHHHEEHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNARTFWSFSLGANGYGLMAVGLYGLSRRHSSLRDWWPMLLPVTLTLSAAITPWYVDNGL
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
RASVFNGNAAILLALSGLVIARDFFQERLTARFGLSAAIFVATSLSALVVLGFTFPNDAP
EEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCC
LPPRYAFFLLIICHFAVALFVLVLVQERAEEKLTRLANTDMLTGVPNRQHFFSSLPKSLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHCHHHCC
PGDAFVLIDIDFFKSVNDRFGHDRGDIVLVDVARTIARSIPPSSVFGRLGGEEFSLFVRG
CCCEEEEEEEHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHCCCCCEEEEEEEC
ETEASAFALAEQIREAVNTLDLVFEGKQVSTTVSAGVALWEANLTEQDIQKRADQALYSA
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHH
KNNGRNRVELFTGIGLTDSSPAPERRLARAG
HCCCCCEEEEEEECCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MDLATVLLLHKSSFIVGAICFFYVRWRSGATPGLGVLAVGFSLLAIASTLAGLDERLHMS
CCHHHEEHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNARTFWSFSLGANGYGLMAVGLYGLSRRHSSLRDWWPMLLPVTLTLSAAITPWYVDNGL
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCC
RASVFNGNAAILLALSGLVIARDFFQERLTARFGLSAAIFVATSLSALVVLGFTFPNDAP
EEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCC
LPPRYAFFLLIICHFAVALFVLVLVQERAEEKLTRLANTDMLTGVPNRQHFFSSLPKSLG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHCHHHCC
PGDAFVLIDIDFFKSVNDRFGHDRGDIVLVDVARTIARSIPPSSVFGRLGGEEFSLFVRG
CCCEEEEEEEHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHCCCCCEEEEEEEC
ETEASAFALAEQIREAVNTLDLVFEGKQVSTTVSAGVALWEANLTEQDIQKRADQALYSA
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHH
KNNGRNRVELFTGIGLTDSSPAPERRLARAG
HCCCCCEEEEEEECCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]