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The map label for this gene is macB [H]

Identifier: 209549304

GI number: 209549304

Start: 1739351

End: 1740553

Strand: Direct

Name: macB [H]

Synonym: Rleg2_1708

Alternate gene names: 209549304

Gene position: 1739351-1740553 (Clockwise)

Preceding gene: 209549303

Following gene: 209549305

Centisome position: 38.33

GC content: 65.09

Gene sequence:

>1203_bases
ATGTTCTTTGAGACGCTGAAGCTGGCATTGCGCGCCATCAGCCGCAACATGCTCCGTTCCTTCCTGACCGTGCTCGGCGT
CGTCATCGGCGTTGCCGCCGTCATCGCGCTGGTGACGATCGGCAACGGCACGACCGCGCAGGTCTCGACCGAATTGTCGC
GACTCGGCACCAATATGCTGTTCGTCCGCCCCGGCCAGTTCGGCCCCGGCCGGGCGAGCTCCGAGGCCAAGCGCTTCAGC
GTCAAGGACGTCGCTGCCATCCGCGACCAGATCGGCGGCCTGAGGGCCGTGGCGCCGCTCAACCAGTCCACGGCGACAGT
CATCTCAGGCGGCCAGAACCATTCGACCAGTGTCTCCGGCACCACCAACGACTATTTCGTCGCACAGGATTGGAACCTGG
CGCTCGGCCGCACTTTTACCCTCGCCGAGGAGCGCGGCCAGTCCCGCTGCATCATCGGCGAAACGGTGCGCTCGCAGCTC
TTCGGCGCCGCCGATCCCACCGGCCAGCAGATCCGCGTCGGCAAGGTCTCATGCCCCGTCATCGGCGTGCTTGCCAAGCG
CGGCCAGTCCGGCATGGGCACCGATCAGGACGATGTCGTCATCATGCCGGTCAAGGTGTTCCAGCGACGCATCAGCGGCA
ACAGCAACGTGCCGCAGATCATCATCTCGGCGCGCGACGGGGTTTCCACAGCCAAGGTGCAGTCCGATGTCGAAGATCTG
CTGCGCGAGCGCCGCAAGATCATCCCCGGCCGGCAGGACGATTTCAACGTCAACGACATGACCCAGATCGCCGAGGCGAT
GACCGGCACGACGACGCTGCTGACCGGCCTGCTCGGCGCCGTTGCCGCTATCAGCCTGCTCGTCGGCGGCATCGGCATCA
TGAACATCATGCTGGTTTCCGTCACCGAGCGCACCCGCGAAATCGGCATTCGCCTGGCGATCGGCGCGCTCGAAAACCAG
GTGCTCACCCAGTTCCTGGTCGAAGCCGTGGCGCTCTCGCTCTTCGGCGGAATCACCGGCATCGTGCTTGGCCTCAGCCT
CGGCTTCGGCGCTGTGACGCTGCTGAAAGTCCCCTTCGTCTTCAGCCCAATGATGATCGCCGTCGCCTTCCTCTTCTCCG
CCGCAATCGGCATGATCTTCGGCTATTTCCCGGCGAGACGGGCAGCGCAGCTGAACCCGATCGAGGCGCTGCGGCACGAG
TGA

Upstream 100 bases:

>100_bases
GTCACACATGAGCCCGATATCGCCGCCTATGCGCAGCGGCTGCTCAGGTTCGTCGACGGCAAGCTGGAGACCGAGGTGGA
GCATCGCAGGAGGGCGGATC

Downstream 100 bases:

>100_bases
CCCTGATGAATGCGTCATGGCAGGGTGCATGGGGATCTCATCATTGGCTACGCTGGATGGATCGCTGTACGAGTGCTTGA
GATCCCTCCGCGATGTCGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MFFETLKLALRAISRNMLRSFLTVLGVVIGVAAVIALVTIGNGTTAQVSTELSRLGTNMLFVRPGQFGPGRASSEAKRFS
VKDVAAIRDQIGGLRAVAPLNQSTATVISGGQNHSTSVSGTTNDYFVAQDWNLALGRTFTLAEERGQSRCIIGETVRSQL
FGAADPTGQQIRVGKVSCPVIGVLAKRGQSGMGTDQDDVVIMPVKVFQRRISGNSNVPQIIISARDGVSTAKVQSDVEDL
LRERRKIIPGRQDDFNVNDMTQIAEAMTGTTTLLTGLLGAVAAISLLVGGIGIMNIMLVSVTERTREIGIRLAIGALENQ
VLTQFLVEAVALSLFGGITGIVLGLSLGFGAVTLLKVPFVFSPMMIAVAFLFSAAIGMIFGYFPARRAAQLNPIEALRHE

Sequences:

>Translated_400_residues
MFFETLKLALRAISRNMLRSFLTVLGVVIGVAAVIALVTIGNGTTAQVSTELSRLGTNMLFVRPGQFGPGRASSEAKRFS
VKDVAAIRDQIGGLRAVAPLNQSTATVISGGQNHSTSVSGTTNDYFVAQDWNLALGRTFTLAEERGQSRCIIGETVRSQL
FGAADPTGQQIRVGKVSCPVIGVLAKRGQSGMGTDQDDVVIMPVKVFQRRISGNSNVPQIIISARDGVSTAKVQSDVEDL
LRERRKIIPGRQDDFNVNDMTQIAEAMTGTTTLLTGLLGAVAAISLLVGGIGIMNIMLVSVTERTREIGIRLAIGALENQ
VLTQFLVEAVALSLFGGITGIVLGLSLGFGAVTLLKVPFVFSPMMIAVAFLFSAAIGMIFGYFPARRAAQLNPIEALRHE
>Mature_400_residues
MFFETLKLALRAISRNMLRSFLTVLGVVIGVAAVIALVTIGNGTTAQVSTELSRLGTNMLFVRPGQFGPGRASSEAKRFS
VKDVAAIRDQIGGLRAVAPLNQSTATVISGGQNHSTSVSGTTNDYFVAQDWNLALGRTFTLAEERGQSRCIIGETVRSQL
FGAADPTGQQIRVGKVSCPVIGVLAKRGQSGMGTDQDDVVIMPVKVFQRRISGNSNVPQIIISARDGVSTAKVQSDVEDL
LRERRKIIPGRQDDFNVNDMTQIAEAMTGTTTLLTGLLGAVAAISLLVGGIGIMNIMLVSVTERTREIGIRLAIGALENQ
VLTQFLVEAVALSLFGGITGIVLGLSLGFGAVTLLKVPFVFSPMMIAVAFLFSAAIGMIFGYFPARRAAQLNPIEALRHE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=403, Percent_Identity=36.7245657568238, Blast_Score=210, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42494; Mature: 42494

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFETLKLALRAISRNMLRSFLTVLGVVIGVAAVIALVTIGNGTTAQVSTELSRLGTNML
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEE
FVRPGQFGPGRASSEAKRFSVKDVAAIRDQIGGLRAVAPLNQSTATVISGGQNHSTSVSG
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHEEECCCCCCCCCCC
TTNDYFVAQDWNLALGRTFTLAEERGQSRCIIGETVRSQLFGAADPTGQQIRVGKVSCPV
CCCCEEEEECCCEECCCEEEEHHHCCCCCEEEHHHHHHHHCCCCCCCCCEEEECCCCCHH
IGVLAKRGQSGMGTDQDDVVIMPVKVFQRRISGNSNVPQIIISARDGVSTAKVQSDVEDL
HHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHH
LRERRKIIPGRQDDFNVNDMTQIAEAMTGTTTLLTGLLGAVAAISLLVGGIGIMNIMLVS
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTERTREIGIRLAIGALENQVLTQFLVEAVALSLFGGITGIVLGLSLGFGAVTLLKVPFV
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSPMMIAVAFLFSAAIGMIFGYFPARRAAQLNPIEALRHE
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHCCC
>Mature Secondary Structure
MFFETLKLALRAISRNMLRSFLTVLGVVIGVAAVIALVTIGNGTTAQVSTELSRLGTNML
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEE
FVRPGQFGPGRASSEAKRFSVKDVAAIRDQIGGLRAVAPLNQSTATVISGGQNHSTSVSG
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHEEECCCCCCCCCCC
TTNDYFVAQDWNLALGRTFTLAEERGQSRCIIGETVRSQLFGAADPTGQQIRVGKVSCPV
CCCCEEEEECCCEECCCEEEEHHHCCCCCEEEHHHHHHHHCCCCCCCCCEEEECCCCCHH
IGVLAKRGQSGMGTDQDDVVIMPVKVFQRRISGNSNVPQIIISARDGVSTAKVQSDVEDL
HHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHH
LRERRKIIPGRQDDFNVNDMTQIAEAMTGTTTLLTGLLGAVAAISLLVGGIGIMNIMLVS
HHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTERTREIGIRLAIGALENQVLTQFLVEAVALSLFGGITGIVLGLSLGFGAVTLLKVPFV
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSPMMIAVAFLFSAAIGMIFGYFPARRAAQLNPIEALRHE
HHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA