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The map label for this gene is yaeL [C]

Identifier: 209549188

GI number: 209549188

Start: 1613305

End: 1614432

Strand: Direct

Name: yaeL [C]

Synonym: Rleg2_1589

Alternate gene names: 209549188

Gene position: 1613305-1614432 (Clockwise)

Preceding gene: 209549187

Following gene: 209549189

Centisome position: 35.55

GC content: 60.2

Gene sequence:

>1128_bases
GTGATGGCCGATATATACACATTCCTGATGGGGAATATCGTCACCTTCATCCTCGTGCTCTCACTGCTCGTCTTCGTGCA
CGAGATGGGCCACTACCTCGTCGGACGCTGGAGCGGCATCCGCATCCTTGCCTTCTCTGTCGGTTTCGGTCCCGAGATAT
TCGGCTTCAACGACCGCCACGGAACGCGCTGGAAGATCTCGGTGATCCCGCTTGGCGGTTACGTCCGTTTCTTCGGCGAC
GAAGACGCGTCGAGCAAGCCCGACAGCGACAAGCTCGCCGCCATGTCCGAGGAGGACAGGGCGCGCTCCTTTGCCGGCGC
AAAACTGTGGAAACGTGCTGCGACCGTCGCCGCCGGCCCGATCGCCAATTTCCTGCTGGCGATTGCCATCTTTACCCTTC
TTTTCTCGATCTACGGCCGTTCCGTCGCCGATCCCGTCGTGTCCGAAGTCACGCCGGATGGTGTGGCGGCCGCCGCCGGC
ATCCTTCCGGGCGATCTGCTGGTCGCCATCGACGGCGGCAAGGTCGAGACCTTCGACGACGTGCGCCGCTATGTCGCCAT
CCGCCCGAGCCAGCAGATCGTCGTCACCATCGAGCGGGGCGGCCAAAAGCTGGACTTGCCGATGGTGCCGCAACGCGTCG
ACAGGACCGACCAGTTCGGCAACAAGATCGAAGTCGGCCAGATCGGTATCGTCACCAGCAAGGAAGTCGGCAATTTCCGC
CTGCAGACGTACACGCCGCTCCAGGCGCTGCGCGAAAGTGTGATCGAAACCCGGGATATCGTCACCGGCACATTCAAATA
TATCGGCAATATTTTCCGCGGTACGATGCGGGCCGATCAACTGGGTGGGCCGATCCGCGTTGCGCAAGCCTCGGGCCAGA
TGGCTTCGCTTGGGATAGGGGCAGTGTTGCAGCTTGCCGCCATGCTTTCAGTTTCGATAGGATTGCTTAACCTGATGCCG
GTTCCGGTACTTGATGGCGGCCACCTGATGTTCTATGCGGTGGAAGCGGTCAGAGGAAAACCGCTGGGCGCCAAGGCTCA
GGAAATCGCATTTCGCATTGGCTTGGCCATGATACTAACATTGATGGTTTTCACGACCTGGAACGACGTTGGCGCGATCA
GAGGGTAA

Upstream 100 bases:

>100_bases
GGATTATTTTCCCTGATAAAGGGGACTGCGATGACGTCGCTCGGCGCGGCCTTGTTCGGCCTTTGATGACGCGGCAGCCT
GACGGAAGGAACTGATAGAA

Downstream 100 bases:

>100_bases
ACGCGCAAAGCAAGGGAATTACTATTTATTTACGATGTTTCAAGGCTGTAGTGGCGAATGGGTCACGCTTCGAAATGAAG
TAAACAGAAATTAACGACCT

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MMADIYTFLMGNIVTFILVLSLLVFVHEMGHYLVGRWSGIRILAFSVGFGPEIFGFNDRHGTRWKISVIPLGGYVRFFGD
EDASSKPDSDKLAAMSEEDRARSFAGAKLWKRAATVAAGPIANFLLAIAIFTLLFSIYGRSVADPVVSEVTPDGVAAAAG
ILPGDLLVAIDGGKVETFDDVRRYVAIRPSQQIVVTIERGGQKLDLPMVPQRVDRTDQFGNKIEVGQIGIVTSKEVGNFR
LQTYTPLQALRESVIETRDIVTGTFKYIGNIFRGTMRADQLGGPIRVAQASGQMASLGIGAVLQLAAMLSVSIGLLNLMP
VPVLDGGHLMFYAVEAVRGKPLGAKAQEIAFRIGLAMILTLMVFTTWNDVGAIRG

Sequences:

>Translated_375_residues
MMADIYTFLMGNIVTFILVLSLLVFVHEMGHYLVGRWSGIRILAFSVGFGPEIFGFNDRHGTRWKISVIPLGGYVRFFGD
EDASSKPDSDKLAAMSEEDRARSFAGAKLWKRAATVAAGPIANFLLAIAIFTLLFSIYGRSVADPVVSEVTPDGVAAAAG
ILPGDLLVAIDGGKVETFDDVRRYVAIRPSQQIVVTIERGGQKLDLPMVPQRVDRTDQFGNKIEVGQIGIVTSKEVGNFR
LQTYTPLQALRESVIETRDIVTGTFKYIGNIFRGTMRADQLGGPIRVAQASGQMASLGIGAVLQLAAMLSVSIGLLNLMP
VPVLDGGHLMFYAVEAVRGKPLGAKAQEIAFRIGLAMILTLMVFTTWNDVGAIRG
>Mature_375_residues
MMADIYTFLMGNIVTFILVLSLLVFVHEMGHYLVGRWSGIRILAFSVGFGPEIFGFNDRHGTRWKISVIPLGGYVRFFGD
EDASSKPDSDKLAAMSEEDRARSFAGAKLWKRAATVAAGPIANFLLAIAIFTLLFSIYGRSVADPVVSEVTPDGVAAAAG
ILPGDLLVAIDGGKVETFDDVRRYVAIRPSQQIVVTIERGGQKLDLPMVPQRVDRTDQFGNKIEVGQIGIVTSKEVGNFR
LQTYTPLQALRESVIETRDIVTGTFKYIGNIFRGTMRADQLGGPIRVAQASGQMASLGIGAVLQLAAMLSVSIGLLNLMP
VPVLDGGHLMFYAVEAVRGKPLGAKAQEIAFRIGLAMILTLMVFTTWNDVGAIRG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=229, Percent_Identity=31.8777292576419, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40540; Mature: 40540

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMADIYTFLMGNIVTFILVLSLLVFVHEMGHYLVGRWSGIRILAFSVGFGPEIFGFNDRH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEECCCCEECCCCCCC
GTRWKISVIPLGGYVRFFGDEDASSKPDSDKLAAMSEEDRARSFAGAKLWKRAATVAAGP
CCEEEEEEEECCCEEEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IANFLLAIAIFTLLFSIYGRSVADPVVSEVTPDGVAAAAGILPGDLLVAIDGGKVETFDD
HHHHHHHHHHHHHHHHHHCCHHCCHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCHHH
VRRYVAIRPSQQIVVTIERGGQKLDLPMVPQRVDRTDQFGNKIEVGQIGIVTSKEVGNFR
HHHHEEECCCCEEEEEEECCCCEECCCCCCHHHCCHHHCCCEEEECEEEEEECCCCCCEE
LQTYTPLQALRESVIETRDIVTGTFKYIGNIFRGTMRADQLGGPIRVAQASGQMASLGIG
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
AVLQLAAMLSVSIGLLNLMPVPVLDGGHLMFYAVEAVRGKPLGAKAQEIAFRIGLAMILT
HHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHH
LMVFTTWNDVGAIRG
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MMADIYTFLMGNIVTFILVLSLLVFVHEMGHYLVGRWSGIRILAFSVGFGPEIFGFNDRH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEECCCCEECCCCCCC
GTRWKISVIPLGGYVRFFGDEDASSKPDSDKLAAMSEEDRARSFAGAKLWKRAATVAAGP
CCEEEEEEEECCCEEEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
IANFLLAIAIFTLLFSIYGRSVADPVVSEVTPDGVAAAAGILPGDLLVAIDGGKVETFDD
HHHHHHHHHHHHHHHHHHCCHHCCHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCHHH
VRRYVAIRPSQQIVVTIERGGQKLDLPMVPQRVDRTDQFGNKIEVGQIGIVTSKEVGNFR
HHHHEEECCCCEEEEEEECCCCEECCCCCCHHHCCHHHCCCEEEECEEEEEECCCCCCEE
LQTYTPLQALRESVIETRDIVTGTFKYIGNIFRGTMRADQLGGPIRVAQASGQMASLGIG
EEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
AVLQLAAMLSVSIGLLNLMPVPVLDGGHLMFYAVEAVRGKPLGAKAQEIAFRIGLAMILT
HHHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEEEHHCCCCCCCHHHHHHHHHHHHHHHH
LMVFTTWNDVGAIRG
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]