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The map label for this gene is betA [C]

Identifier: 209548986

GI number: 209548986

Start: 1404724

End: 1406379

Strand: Direct

Name: betA [C]

Synonym: Rleg2_1383

Alternate gene names: 209548986

Gene position: 1404724-1406379 (Clockwise)

Preceding gene: 209548985

Following gene: 209548987

Centisome position: 30.96

GC content: 63.04

Gene sequence:

>1656_bases
ATGGGCTTCGATTATATCATCACAGGCGCCGGTCCCGCGGGCTGCGTTCTTGCAAGCCGGCTGAGCGAAGATCCCGATAT
CCGCGTCCTCCTGCTCGAAGCAGGCGGCGGCGACTGGAATCCCCTCTTTCACATGCCGGCGGGCTTCGCCAAGATGACCA
AGGGCGTGGCCAGCTGGGGATGGCAAACCGTTCCCCAGAAGCACATGAAAGACCGGGTGCTTCGCTATACCCAGGCGAAG
GTCATCGGCGGCGGCTCTTCGATCAACGCCCAGCTCTATACGCGTGGAAATGCGGCCGATTACGACCTCTGGGCCAGTGA
AGACGGCTGCGAGGGCTGGGACTATCGCTCGATCCTGCCCTATTTCAAACGCGCCGAGGACAATCAGCGCTTCGCCGACG
ACTACCACGCCTATGGCGGTCCGCTGGGGGTCTCGATGCCGGCAGCACCCCTGCCGATCTGCGACGCCTATATCCGTGCA
GGTCAGGAGCTCGGCATTCCCTATAATCACGACTTCAACGGCCGCCAGCAGGCGGGTGTTGGATTTTATCAGCTGACGCA
GCGCAATCGCCGCCGGTCCTCGGCATCGCTTGCCTATCTCTCGCCGATCAAGGAGCGGAAGAACCTGACGGTCAGGACAG
GCGCGCGTGTTACGCGGATCATTGTCGAAGGAGGCCGTGCGACAGGCGTCGAGATCGCCACCGCGGGCGGCTCGGAGATC
GTGCGCGCCGAGCGTGAGGTCCTGGTGTCGTCAGGCGCGATCGGATCGCCGAAGCTTCTTCTGCAGTCCGGCATCGGGCC
GGCCGATCATCTGAAATCGGTGGGCGTCAAGGTGAACCACGATCTGCCCGGTGTCGGCGGCAACCTGCAGGATCACCTGG
ACCTTTTCGTCATCGCCGAATGCACCGGCGATCACACCTATGACGGCGTTGCAAAGCTTCACCGCACACTCTGGGCCGGG
GTTCAATATGTCCTGTTCCGCACCGGTCCTGTGGCGTCGTCGCTCTTCGAGACCGGCGGCTTCTGGTATGCCGATCCCGA
GGCTCGGTCTCCCGATATCCAGTTTCATCTCGGCTTGGGATCGGGCATCGAAGCCGGCGTCGAGCGGCTCAAAAATGCGG
GCGTGACGCTGAATTCCGCCTATCTGCATCCGCGCTCCCTCGGGACGGTGCGTCTGTCATCCGCCGACCCGGCTGCCGCG
CCCCTGATCGATCCGAACTACTGGTCCGATCCGCACGACAGGCAGATGTCGCTGGAGGGGCTCAAGATTGCCCGCGAGAT
CATGCAGCAGGCGGCGCTGAAGCCCTTTGTCATGGCCGAAAGGCTTCCCGGGCCGAAGGTCATGACCGACGAGCAGCTGT
TCGACTATGGCTGCGCCAATGCAAAGACCGACCATCATCCTGTGGGCACCTGCAAGATGGGAACGGGGCCCGACGCCGTT
GTCGGGCTGGATCTCAAGGTTCATGGCCTCGAAGGCCTCCGCGTCTGCGATTCCTCGGTCATGCCGCGCGTGCCGTCCTG
CAATACCAACGCGCCGACGATCATGGTCGGCGAAAAGGGATCGGACCTGATCAGGGGCTTGCCTGCGCTGCCGTCGGCAA
TCTTTGCCTATGAACGCAACGATGTCAGGCCTCGGGCCCGCGCCGAAATCCGCTAA

Upstream 100 bases:

>100_bases
TGCCAGCCAGGCGCTCAGAGTTGCCGACCACATCGCGTCGAAGGACTTGCAGGCAAAATCAGATCCATTGGCGCATGCCG
GGCACAAATAGGACGGTAAA

Downstream 100 bases:

>100_bases
GGAGTAGTGATATGTCTGAAGTGAGAGTTGCAGTGCTAGGCGCCTCGGGCTGGATGGGAAAGGTCCATACGATGGCCTAC
CAGACCTTTCCGCATTTCTT

Product: glucose-methanol-choline oxidoreductase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MGFDYIITGAGPAGCVLASRLSEDPDIRVLLLEAGGGDWNPLFHMPAGFAKMTKGVASWGWQTVPQKHMKDRVLRYTQAK
VIGGGSSINAQLYTRGNAADYDLWASEDGCEGWDYRSILPYFKRAEDNQRFADDYHAYGGPLGVSMPAAPLPICDAYIRA
GQELGIPYNHDFNGRQQAGVGFYQLTQRNRRRSSASLAYLSPIKERKNLTVRTGARVTRIIVEGGRATGVEIATAGGSEI
VRAEREVLVSSGAIGSPKLLLQSGIGPADHLKSVGVKVNHDLPGVGGNLQDHLDLFVIAECTGDHTYDGVAKLHRTLWAG
VQYVLFRTGPVASSLFETGGFWYADPEARSPDIQFHLGLGSGIEAGVERLKNAGVTLNSAYLHPRSLGTVRLSSADPAAA
PLIDPNYWSDPHDRQMSLEGLKIAREIMQQAALKPFVMAERLPGPKVMTDEQLFDYGCANAKTDHHPVGTCKMGTGPDAV
VGLDLKVHGLEGLRVCDSSVMPRVPSCNTNAPTIMVGEKGSDLIRGLPALPSAIFAYERNDVRPRARAEIR

Sequences:

>Translated_551_residues
MGFDYIITGAGPAGCVLASRLSEDPDIRVLLLEAGGGDWNPLFHMPAGFAKMTKGVASWGWQTVPQKHMKDRVLRYTQAK
VIGGGSSINAQLYTRGNAADYDLWASEDGCEGWDYRSILPYFKRAEDNQRFADDYHAYGGPLGVSMPAAPLPICDAYIRA
GQELGIPYNHDFNGRQQAGVGFYQLTQRNRRRSSASLAYLSPIKERKNLTVRTGARVTRIIVEGGRATGVEIATAGGSEI
VRAEREVLVSSGAIGSPKLLLQSGIGPADHLKSVGVKVNHDLPGVGGNLQDHLDLFVIAECTGDHTYDGVAKLHRTLWAG
VQYVLFRTGPVASSLFETGGFWYADPEARSPDIQFHLGLGSGIEAGVERLKNAGVTLNSAYLHPRSLGTVRLSSADPAAA
PLIDPNYWSDPHDRQMSLEGLKIAREIMQQAALKPFVMAERLPGPKVMTDEQLFDYGCANAKTDHHPVGTCKMGTGPDAV
VGLDLKVHGLEGLRVCDSSVMPRVPSCNTNAPTIMVGEKGSDLIRGLPALPSAIFAYERNDVRPRARAEIR
>Mature_550_residues
GFDYIITGAGPAGCVLASRLSEDPDIRVLLLEAGGGDWNPLFHMPAGFAKMTKGVASWGWQTVPQKHMKDRVLRYTQAKV
IGGGSSINAQLYTRGNAADYDLWASEDGCEGWDYRSILPYFKRAEDNQRFADDYHAYGGPLGVSMPAAPLPICDAYIRAG
QELGIPYNHDFNGRQQAGVGFYQLTQRNRRRSSASLAYLSPIKERKNLTVRTGARVTRIIVEGGRATGVEIATAGGSEIV
RAEREVLVSSGAIGSPKLLLQSGIGPADHLKSVGVKVNHDLPGVGGNLQDHLDLFVIAECTGDHTYDGVAKLHRTLWAGV
QYVLFRTGPVASSLFETGGFWYADPEARSPDIQFHLGLGSGIEAGVERLKNAGVTLNSAYLHPRSLGTVRLSSADPAAAP
LIDPNYWSDPHDRQMSLEGLKIAREIMQQAALKPFVMAERLPGPKVMTDEQLFDYGCANAKTDHHPVGTCKMGTGPDAVV
GLDLKVHGLEGLRVCDSSVMPRVPSCNTNAPTIMVGEKGSDLIRGLPALPSAIFAYERNDVRPRARAEIR

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=540, Percent_Identity=41.1111111111111, Blast_Score=383, Evalue=1e-106,
Organism=Escherichia coli, GI1786503, Length=544, Percent_Identity=41.5441176470588, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17532301, Length=561, Percent_Identity=37.0766488413547, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24642055, Length=576, Percent_Identity=37.1527777777778, Blast_Score=329, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24642042, Length=567, Percent_Identity=37.9188712522046, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24642048, Length=574, Percent_Identity=36.9337979094077, Blast_Score=312, Evalue=5e-85,
Organism=Drosophila melanogaster, GI45551458, Length=570, Percent_Identity=37.0175438596491, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI45549471, Length=570, Percent_Identity=37.0175438596491, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI24642037, Length=574, Percent_Identity=36.411149825784, Blast_Score=299, Evalue=4e-81,
Organism=Drosophila melanogaster, GI17137792, Length=557, Percent_Identity=37.342908438061, Blast_Score=299, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24642059, Length=565, Percent_Identity=36.6371681415929, Blast_Score=292, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24642039, Length=567, Percent_Identity=35.2733686067019, Blast_Score=289, Evalue=4e-78,
Organism=Drosophila melanogaster, GI24650267, Length=574, Percent_Identity=34.6689895470383, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI18859995, Length=573, Percent_Identity=33.5078534031414, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24642035, Length=571, Percent_Identity=33.4500875656743, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24642051, Length=564, Percent_Identity=34.5744680851064, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI18859993, Length=564, Percent_Identity=33.3333333333333, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24642057, Length=575, Percent_Identity=30.0869565217391, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24645930, Length=572, Percent_Identity=26.2237762237762, Blast_Score=144, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 59574; Mature: 59443

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00623 GMC_OXRED_1 ; PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFDYIITGAGPAGCVLASRLSEDPDIRVLLLEAGGGDWNPLFHMPAGFAKMTKGVASWG
CCCEEEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEECCCCHHHHHHHHHHCC
WQTVPQKHMKDRVLRYTQAKVIGGGSSINAQLYTRGNAADYDLWASEDGCEGWDYRSILP
CCCCCHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCEECCCCCCCCCCHHHHHH
YFKRAEDNQRFADDYHAYGGPLGVSMPAAPLPICDAYIRAGQELGIPYNHDFNGRQQAGV
HHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCHHCCC
GFYQLTQRNRRRSSASLAYLSPIKERKNLTVRTGARVTRIIVEGGRATGVEIATAGGSEI
CHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCEEEEEEEECCCCCCEEEEECCCHHH
VRAEREVLVSSGAIGSPKLLLQSGIGPADHLKSVGVKVNHDLPGVGGNLQDHLDLFVIAE
HHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHCCEEECCCCCCCCCCHHHCCEEEEEEE
CTGDHTYDGVAKLHRTLWAGVQYVLFRTGPVASSLFETGGFWYADPEARSPDIQFHLGLG
CCCCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCCEEEECCCCCCCCEEEEEECC
SGIEAGVERLKNAGVTLNSAYLHPRSLGTVRLSSADPAAAPLIDPNYWSDPHDRQMSLEG
CCHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
LKIAREIMQQAALKPFVMAERLPGPKVMTDEQLFDYGCANAKTDHHPVGTCKMGTGPDAV
HHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCCEE
VGLDLKVHGLEGLRVCDSSVMPRVPSCNTNAPTIMVGEKGSDLIRGLPALPSAIFAYERN
EEEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCHHHHEECCC
DVRPRARAEIR
CCCCCHHCCCC
>Mature Secondary Structure 
GFDYIITGAGPAGCVLASRLSEDPDIRVLLLEAGGGDWNPLFHMPAGFAKMTKGVASWG
CCEEEEECCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEECCCCHHHHHHHHHHCC
WQTVPQKHMKDRVLRYTQAKVIGGGSSINAQLYTRGNAADYDLWASEDGCEGWDYRSILP
CCCCCHHHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCEECCCCCCCCCCHHHHHH
YFKRAEDNQRFADDYHAYGGPLGVSMPAAPLPICDAYIRAGQELGIPYNHDFNGRQQAGV
HHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCHHCCCCCCCCCCCCHHCCC
GFYQLTQRNRRRSSASLAYLSPIKERKNLTVRTGARVTRIIVEGGRATGVEIATAGGSEI
CHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCEEEEEEEECCCCCCEEEEECCCHHH
VRAEREVLVSSGAIGSPKLLLQSGIGPADHLKSVGVKVNHDLPGVGGNLQDHLDLFVIAE
HHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHCCEEECCCCCCCCCCHHHCCEEEEEEE
CTGDHTYDGVAKLHRTLWAGVQYVLFRTGPVASSLFETGGFWYADPEARSPDIQFHLGLG
CCCCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHCCCEEEECCCCCCCCEEEEEECC
SGIEAGVERLKNAGVTLNSAYLHPRSLGTVRLSSADPAAAPLIDPNYWSDPHDRQMSLEG
CCHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
LKIAREIMQQAALKPFVMAERLPGPKVMTDEQLFDYGCANAKTDHHPVGTCKMGTGPDAV
HHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCCEE
VGLDLKVHGLEGLRVCDSSVMPRVPSCNTNAPTIMVGEKGSDLIRGLPALPSAIFAYERN
EEEEEEEECCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCHHHHEECCC
DVRPRARAEIR
CCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]