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The map label for this gene is dinB1 [H]

Identifier: 209548888

GI number: 209548888

Start: 1306257

End: 1307552

Strand: Reverse

Name: dinB1 [H]

Synonym: Rleg2_1285

Alternate gene names: 209548888

Gene position: 1307552-1306257 (Counterclockwise)

Preceding gene: 209548890

Following gene: 209548887

Centisome position: 28.81

GC content: 64.66

Gene sequence:

>1296_bases
ATGATGACGCCCGCGCCCGACAAGACACCCGGCTTCTGTCGCGACTGCCTTGCCGAGCAGAAGGGCGAGGCGCGCCGCTG
CGTGTCTTGCGGCAGCCCCCGTCTGGTGCGCCATCGCGAGCTCTATGCCTTGACGCTTGCGCATATCGATTGCGACGCCT
TCTATGCGGCCGTCGAGAAACGCGACAATCCGGACCTTGCCGACAAGCCTGTAATCATCGGCGGCGGCAAACGCGGCGTC
GTCTCCACCGCCTGCTATATCGCCCGCATCCACGGCGTGCGGTCGGCGATGCCGATGTTCAAGGCGCTGGAAGCCTGCCC
CGAGGCGATCGTCATCCGCCCCGACATGGAAAAATACGTCCGGGTCGGGCGCCAGGTGCGCGCCATGATGCAGGATCTGA
CGCCGCTGGTGCAGCCGCTGTCGATCGACGAGGCCTTCCTGGAGCTTGGCGGCACCGAGAGGCTGCATCACGATCCGCCG
GCCCGCACCCTCGCCAAATTCGCCCGCCGGGTCGAAAAGGAGATCGGCATCAGCGTGTCGGTCGGGCTTTCCTATTGCAA
ATTCCTCGCCAAGGTCGCCTCCGACCTGCAGAAGCCGCGCGGCTTTTCCGTCATCGGCCGCGAGGAAGCGGTCGAGTTTC
TGGCGCCGCGTCCGGTGACCACGATCTGGGGCGTCGGCAAGGCCTTTGCGGCGACGCTGGAGGCTGATGGTATCCGCACC
ATCAGCCAGTTGCAGCAGATGGAGGAAAACGACCTGATGCGCCGCTACGGCAGCATCGGCCAGCGGCTCGCCCGGCTATC
GCGCGGGATCGACGACCGCGAAGTGCATCTCAACGATGCGGCCAAGAGCGTTTCAGCGGAGACCACCTTCTTCGAGGACA
TCTGGCGTTATGACGATCTGGTGCCGATCCTGCGCGATCTCTCGGAAAAGGTCTCCTGGCGGCTGAAGAAAAACGACATC
GCCGGCCAGACCGTGGTCCTGAAGATGAAGACCGCCGACTTCAAGTTACGCACGCGCAACCGCAAGCTCGAAGACCCGAC
CCAGCTTGCCGACCGGATCTTTCGCATCGGCCTCGAGCTTCTCGAAAAAGAAACCGACGGCACGAAGTTCCGGCTGCTCG
GCATCGGCGTCACCGATCTCGGCGATGCCGCCCGCGCCGATCCGCCCGATCTCATCGACCGGCAATCGGGCCGGCGGGCA
GCCGCCGAAGCGGCGATGGACAAGCTGCGCGACAAGTTCGGCAAGAACACCGTCGAGACCGGCTACACCTTCGGCAGCGG
CAAGCGAGATCACTAG

Upstream 100 bases:

>100_bases
CCGGCTCGAAACGAAGATCGTTATCCAAAGGCAAAGCTCCCGCCTCTCTTGAGACTCGGAAGCTTAAGGCGTAGTGTCGC
GGCGTTCAACCTTTGTTCTC

Downstream 100 bases:

>100_bases
AGCAATTCCAGGAAAAGTGCGAAGCGGTTTTCCGTCCGGAATTGCGTTAAAACAAAAGCTTAGAGCGGTTCTGCGCTTCC
GTGAAAAGCTGAACCGCTCT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MMTPAPDKTPGFCRDCLAEQKGEARRCVSCGSPRLVRHRELYALTLAHIDCDAFYAAVEKRDNPDLADKPVIIGGGKRGV
VSTACYIARIHGVRSAMPMFKALEACPEAIVIRPDMEKYVRVGRQVRAMMQDLTPLVQPLSIDEAFLELGGTERLHHDPP
ARTLAKFARRVEKEIGISVSVGLSYCKFLAKVASDLQKPRGFSVIGREEAVEFLAPRPVTTIWGVGKAFAATLEADGIRT
ISQLQQMEENDLMRRYGSIGQRLARLSRGIDDREVHLNDAAKSVSAETTFFEDIWRYDDLVPILRDLSEKVSWRLKKNDI
AGQTVVLKMKTADFKLRTRNRKLEDPTQLADRIFRIGLELLEKETDGTKFRLLGIGVTDLGDAARADPPDLIDRQSGRRA
AAEAAMDKLRDKFGKNTVETGYTFGSGKRDH

Sequences:

>Translated_431_residues
MMTPAPDKTPGFCRDCLAEQKGEARRCVSCGSPRLVRHRELYALTLAHIDCDAFYAAVEKRDNPDLADKPVIIGGGKRGV
VSTACYIARIHGVRSAMPMFKALEACPEAIVIRPDMEKYVRVGRQVRAMMQDLTPLVQPLSIDEAFLELGGTERLHHDPP
ARTLAKFARRVEKEIGISVSVGLSYCKFLAKVASDLQKPRGFSVIGREEAVEFLAPRPVTTIWGVGKAFAATLEADGIRT
ISQLQQMEENDLMRRYGSIGQRLARLSRGIDDREVHLNDAAKSVSAETTFFEDIWRYDDLVPILRDLSEKVSWRLKKNDI
AGQTVVLKMKTADFKLRTRNRKLEDPTQLADRIFRIGLELLEKETDGTKFRLLGIGVTDLGDAARADPPDLIDRQSGRRA
AAEAAMDKLRDKFGKNTVETGYTFGSGKRDH
>Mature_431_residues
MMTPAPDKTPGFCRDCLAEQKGEARRCVSCGSPRLVRHRELYALTLAHIDCDAFYAAVEKRDNPDLADKPVIIGGGKRGV
VSTACYIARIHGVRSAMPMFKALEACPEAIVIRPDMEKYVRVGRQVRAMMQDLTPLVQPLSIDEAFLELGGTERLHHDPP
ARTLAKFARRVEKEIGISVSVGLSYCKFLAKVASDLQKPRGFSVIGREEAVEFLAPRPVTTIWGVGKAFAATLEADGIRT
ISQLQQMEENDLMRRYGSIGQRLARLSRGIDDREVHLNDAAKSVSAETTFFEDIWRYDDLVPILRDLSEKVSWRLKKNDI
AGQTVVLKMKTADFKLRTRNRKLEDPTQLADRIFRIGLELLEKETDGTKFRLLGIGVTDLGDAARADPPDLIDRQSGRRA
AAEAAMDKLRDKFGKNTVETGYTFGSGKRDH

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7705344, Length=105, Percent_Identity=46.6666666666667, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI154350220, Length=281, Percent_Identity=27.4021352313167, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI84043967, Length=342, Percent_Identity=26.6081871345029, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI7706681, Length=273, Percent_Identity=30.03663003663, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786425, Length=301, Percent_Identity=39.8671096345515, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1787432, Length=407, Percent_Identity=24.5700245700246, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17537959, Length=298, Percent_Identity=24.8322147651007, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193205702, Length=219, Percent_Identity=31.5068493150685, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=219, Percent_Identity=31.5068493150685, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI19923006, Length=333, Percent_Identity=25.5255255255255, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355641, Length=295, Percent_Identity=25.0847457627119, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24644984, Length=295, Percent_Identity=25.0847457627119, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 48102; Mature: 48102

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTPAPDKTPGFCRDCLAEQKGEARRCVSCGSPRLVRHRELYALTLAHIDCDAFYAAVEK
CCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RDNPDLADKPVIIGGGKRGVVSTACYIARIHGVRSAMPMFKALEACPEAIVIRPDMEKYV
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHH
RVGRQVRAMMQDLTPLVQPLSIDEAFLELGGTERLHHDPPARTLAKFARRVEKEIGISVS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
VGLSYCKFLAKVASDLQKPRGFSVIGREEAVEFLAPRPVTTIWGVGKAFAATLEADGIRT
HHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCCCHHHHHCHHHHHHHHHHCCHHH
ISQLQQMEENDLMRRYGSIGQRLARLSRGIDDREVHLNDAAKSVSAETTFFEDIWRYDDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VPILRDLSEKVSWRLKKNDIAGQTVVLKMKTADFKLRTRNRKLEDPTQLADRIFRIGLEL
HHHHHHHHHHHHEEHHCCCCCCCEEEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHH
LEKETDGTKFRLLGIGVTDLGDAARADPPDLIDRQSGRRAAAEAAMDKLRDKFGKNTVET
HHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHC
GYTFGSGKRDH
CCCCCCCCCCC
>Mature Secondary Structure
MMTPAPDKTPGFCRDCLAEQKGEARRCVSCGSPRLVRHRELYALTLAHIDCDAFYAAVEK
CCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
RDNPDLADKPVIIGGGKRGVVSTACYIARIHGVRSAMPMFKALEACPEAIVIRPDMEKYV
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHH
RVGRQVRAMMQDLTPLVQPLSIDEAFLELGGTERLHHDPPARTLAKFARRVEKEIGISVS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
VGLSYCKFLAKVASDLQKPRGFSVIGREEAVEFLAPRPVTTIWGVGKAFAATLEADGIRT
HHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHCCCCCHHHHHCHHHHHHHHHHCCHHH
ISQLQQMEENDLMRRYGSIGQRLARLSRGIDDREVHLNDAAKSVSAETTFFEDIWRYDDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
VPILRDLSEKVSWRLKKNDIAGQTVVLKMKTADFKLRTRNRKLEDPTQLADRIFRIGLEL
HHHHHHHHHHHHEEHHCCCCCCCEEEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHH
LEKETDGTKFRLLGIGVTDLGDAARADPPDLIDRQSGRRAAAEAAMDKLRDKFGKNTVET
HHCCCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHC
GYTFGSGKRDH
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]