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The map label for this gene is nuoH1 [H]

Identifier: 209548871

GI number: 209548871

Start: 1285424

End: 1286467

Strand: Direct

Name: nuoH1 [H]

Synonym: Rleg2_1268

Alternate gene names: 209548871

Gene position: 1285424-1286467 (Clockwise)

Preceding gene: 209548870

Following gene: 209548872

Centisome position: 28.33

GC content: 59.58

Gene sequence:

>1044_bases
ATGGATTCTTTCTTTTCGACCTATGTCTTGCCGGCGATCATCATGATCGGTCAGTCGCTGCTGCTTCTGGTCTGCCTGCT
TGTCTTCATCGCCTATGTTCTGCTCGCCGACCGCAAGATCTGGGCGGCCGTGCAGTTGCGCCGCGGCCCGAATGTCGTCG
GTCCCTTCGGCCTGTTCCAGTCTTTCGCCGACCTTCTGAAGTTCGTCTTCAAGGAGCCGATCATTCCGGCCGGCGCCAAC
AAGGCGGTGTTCCTGCTTGCCCCGCTGGTGACGGTGCTTCTGGCATTGTCCACCTGGGCGGTGGTGCCGCTCGCCGACGG
CTGGGTGATCGCCAACATCAATGTCGGCATCCTCTACATCTTCGCGATCTCCTCGCTCGAGGTTTACGGCATCATCATGG
GCGGCTGGGCTTCGAACTCGAAGTATCCGTTCCTTGGTGCGCTGCGTTCGGCTGCGCAGATGGTGTCCTATGAAGTCTCG
ATCGGCTTCGTCATCGTCACCGTGCTTCTCTGCGTCGGCTCGCTGAACCTGACCGATATCGTCAATGCGCAGCATACCGG
CCTCGGCACTATGCTCGGCCTGCCGGCGTCGTTCCTCGACTGGCACTGGCTGTCGCTCTTCCCGATGTTCATCATCTTCT
TCATTTCGGCGCTCGCCGAAACGAACCGTCCGCCCTTCGACCTTCCGGAAGCAGAATCGGAACTGGTTGCCGGCTTCATG
GTCGAATACGGCTCCTCGCCATACATGATGTTCATGCTCGGCGAATATGCGGCCGTCTGCCTGATGTGTTCGCTGACGAC
GATCCTCTTCCTCGGCGGCTGGCTGCCGCCGGTCGACATCTGGATCCTCAACTGGGTCCCGGGCATCATCTGGTTCATGC
TGAAGGCCTGCTTCGTGTTCTTCATGTTCGCGATGGTCAAGGCTTTCGTCCCGCGCTACCGCTACGACCAGCTCATGCGC
CTCGGCTGGAAGGTTTTCCTGCCGCTGTCGCTCGCCATGGTCATCATCGTTGCATTCGTGCTGAAGCTGATGGGATGGGC
ATGA

Upstream 100 bases:

>100_bases
TTTGACGAACCCGATAGCGCGTGCCTCGGCAGTGATGGCGGAGTGCTCGGCATTGGCCCGCAACAACTTCAAAGTCGCGG
CAGAGTAAGGGCAGGGGACT

Downstream 100 bases:

>100_bases
TGACGCCCTCTCTCGTTTCCGGCAAAATTGGAGGTTGAAGATGGGAAGCTTGTCCAGCTCCATCAGCTCGCTGTTCCTCA
AGGAATTCTTCGGCGCGTTC

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H 1; NDH-1 subunit H 1 [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MDSFFSTYVLPAIIMIGQSLLLLVCLLVFIAYVLLADRKIWAAVQLRRGPNVVGPFGLFQSFADLLKFVFKEPIIPAGAN
KAVFLLAPLVTVLLALSTWAVVPLADGWVIANINVGILYIFAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVS
IGFVIVTVLLCVGSLNLTDIVNAQHTGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
VEYGSSPYMMFMLGEYAAVCLMCSLTTILFLGGWLPPVDIWILNWVPGIIWFMLKACFVFFMFAMVKAFVPRYRYDQLMR
LGWKVFLPLSLAMVIIVAFVLKLMGWA

Sequences:

>Translated_347_residues
MDSFFSTYVLPAIIMIGQSLLLLVCLLVFIAYVLLADRKIWAAVQLRRGPNVVGPFGLFQSFADLLKFVFKEPIIPAGAN
KAVFLLAPLVTVLLALSTWAVVPLADGWVIANINVGILYIFAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVS
IGFVIVTVLLCVGSLNLTDIVNAQHTGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
VEYGSSPYMMFMLGEYAAVCLMCSLTTILFLGGWLPPVDIWILNWVPGIIWFMLKACFVFFMFAMVKAFVPRYRYDQLMR
LGWKVFLPLSLAMVIIVAFVLKLMGWA
>Mature_347_residues
MDSFFSTYVLPAIIMIGQSLLLLVCLLVFIAYVLLADRKIWAAVQLRRGPNVVGPFGLFQSFADLLKFVFKEPIIPAGAN
KAVFLLAPLVTVLLALSTWAVVPLADGWVIANINVGILYIFAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVS
IGFVIVTVLLCVGSLNLTDIVNAQHTGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
VEYGSSPYMMFMLGEYAAVCLMCSLTTILFLGGWLPPVDIWILNWVPGIIWFMLKACFVFFMFAMVKAFVPRYRYDQLMR
LGWKVFLPLSLAMVIIVAFVLKLMGWA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=306, Percent_Identity=40.8496732026144, Blast_Score=237, Evalue=1e-62,
Organism=Escherichia coli, GI1788618, Length=340, Percent_Identity=37.3529411764706, Blast_Score=236, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 38542; Mature: 38542

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSFFSTYVLPAIIMIGQSLLLLVCLLVFIAYVLLADRKIWAAVQLRRGPNVVGPFGLFQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
SFADLLKFVFKEPIIPAGANKAVFLLAPLVTVLLALSTWAVVPLADGWVIANINVGILYI
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHH
FAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLCVGSLNLTDI
HHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VNAQHTGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
VEYGSSPYMMFMLGEYAAVCLMCSLTTILFLGGWLPPVDIWILNWVPGIIWFMLKACFVF
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FMFAMVKAFVPRYRYDQLMRLGWKVFLPLSLAMVIIVAFVLKLMGWA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSFFSTYVLPAIIMIGQSLLLLVCLLVFIAYVLLADRKIWAAVQLRRGPNVVGPFGLFQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
SFADLLKFVFKEPIIPAGANKAVFLLAPLVTVLLALSTWAVVPLADGWVIANINVGILYI
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECCHHHHHH
FAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVSIGFVIVTVLLCVGSLNLTDI
HHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
VNAQHTGLGTMLGLPASFLDWHWLSLFPMFIIFFISALAETNRPPFDLPEAESELVAGFM
CCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
VEYGSSPYMMFMLGEYAAVCLMCSLTTILFLGGWLPPVDIWILNWVPGIIWFMLKACFVF
HHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FMFAMVKAFVPRYRYDQLMRLGWKVFLPLSLAMVIIVAFVLKLMGWA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA