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The map label for this gene is xylR [H]

Identifier: 209548818

GI number: 209548818

Start: 1225298

End: 1226479

Strand: Reverse

Name: xylR [H]

Synonym: Rleg2_1215

Alternate gene names: 209548818

Gene position: 1226479-1225298 (Counterclockwise)

Preceding gene: 209548820

Following gene: 209548817

Centisome position: 27.03

GC content: 63.11

Gene sequence:

>1182_bases
ATGGCACCGACACTTTCTGCCACGCAGACGCCCATCGCACGAAAAATCTCAACTCATGCCGTGATCCGGACCGTTTTGGC
GAGAGGCTCGATTTCCCGCGCCGACATTGCCAAGCTGACCGGACTGTCGAAACAGACGATTTCCGATGTCGTGCGCGACC
TCGAGGATGACGGATGGCTGAAACCTGTGGGCCAGACCGATGGTCGCCCGGGCCGCAATGCGATTACCTATGAACTTAAC
GCCAGGGCGGGTCTTGCCGTCTCCATCGATCTCGGCGGCACCAAGATCGCAGCGGCGATCTGCGATCTGCTGGGCAACAT
CATTGCCGAAACCAAAGTGGCCACCGACCGCCGCGGCGGAATGCATCTCGTTAATCAGTTCAGCGATCTCATCGTCGAAC
TCGCGCTTGCGGCCGGAACGACCGCCGACAAGCTCCGTCTCGTGGTTCTCGGCAGTCCCGGCGTGCTCGATCCCGCCACC
GGCCATATCAATGTGGCGCCGAATATCCCCGGCATCGATGCGATCAATCTGCGGCAGGTCTTCTCCGACAGAATGGGCAT
TCCGGTGATCGTCGAAAATGACGTCAACCTCGCCGCGCAAGGCGAAAGATGGCGGGGACACGGTGTCGAAACCGGCAATT
TTGCGTTCGTCGCGCTCGGAACGGGCGTCGGCATGGGCATCATCGCCAATGGCGCACTGCTGCGCGGCGCACGGGGCGCG
GCCGGCGAGATCGCCTATCTTCCGATCGGCGGCGATGTTTTCGATCCCGGCGGGTTTACGCTCGGGACCTTCGAGAGCGC
GGTCGGCAGTGTCGCGATGTTACGCCGCTACACCGGCTTCGGCGGGCGCAACGCCGCCACCGTCGCCGATCTCTTCGCCG
CCTTCAATGCGGGAGATACCAGCGCCGTCGCCGCAATCGAAGAGACGGCAAGGCTGGTGGCGCTCGCCATTGCCGGGATC
GGAGCGACTCTCGACCCCGAACTGGTGATCACCGGCGGCAGCATCGGCGCAAGACCGGAATTGGTAAACGCCATCCGGGG
TTTCCTGCCGCGCTGCACGCCTTATCCGCCGCGCATCGAGATCAGCCGGTTTGGGAACCGGGCGGCCCTCATGGGAGGCA
TGGGGGTCGCGGTCGAGCGTATGCACGACGATCTGTTCGGCGTGAAATTGAAGGACGCTTGA

Upstream 100 bases:

>100_bases
TGACGAAGTTGAGCCGCAACCGTCCTTTTCGCGATGGTCGCGGGGTCAAGATCGGCCCTTGATTAGGTATATGCTCCGAA
CTAATTGGAAGAGCTAGCCG

Downstream 100 bases:

>100_bases
TCGGCCTGCGCCACTTGAGAACTGCGGTAAATGCGCTAGATTTTCCGCCATGATAACAGCGACACAGATACGCGGCGCGC
GCGCCATGATCGGGATGAGT

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MAPTLSATQTPIARKISTHAVIRTVLARGSISRADIAKLTGLSKQTISDVVRDLEDDGWLKPVGQTDGRPGRNAITYELN
ARAGLAVSIDLGGTKIAAAICDLLGNIIAETKVATDRRGGMHLVNQFSDLIVELALAAGTTADKLRLVVLGSPGVLDPAT
GHINVAPNIPGIDAINLRQVFSDRMGIPVIVENDVNLAAQGERWRGHGVETGNFAFVALGTGVGMGIIANGALLRGARGA
AGEIAYLPIGGDVFDPGGFTLGTFESAVGSVAMLRRYTGFGGRNAATVADLFAAFNAGDTSAVAAIEETARLVALAIAGI
GATLDPELVITGGSIGARPELVNAIRGFLPRCTPYPPRIEISRFGNRAALMGGMGVAVERMHDDLFGVKLKDA

Sequences:

>Translated_393_residues
MAPTLSATQTPIARKISTHAVIRTVLARGSISRADIAKLTGLSKQTISDVVRDLEDDGWLKPVGQTDGRPGRNAITYELN
ARAGLAVSIDLGGTKIAAAICDLLGNIIAETKVATDRRGGMHLVNQFSDLIVELALAAGTTADKLRLVVLGSPGVLDPAT
GHINVAPNIPGIDAINLRQVFSDRMGIPVIVENDVNLAAQGERWRGHGVETGNFAFVALGTGVGMGIIANGALLRGARGA
AGEIAYLPIGGDVFDPGGFTLGTFESAVGSVAMLRRYTGFGGRNAATVADLFAAFNAGDTSAVAAIEETARLVALAIAGI
GATLDPELVITGGSIGARPELVNAIRGFLPRCTPYPPRIEISRFGNRAALMGGMGVAVERMHDDLFGVKLKDA
>Mature_392_residues
APTLSATQTPIARKISTHAVIRTVLARGSISRADIAKLTGLSKQTISDVVRDLEDDGWLKPVGQTDGRPGRNAITYELNA
RAGLAVSIDLGGTKIAAAICDLLGNIIAETKVATDRRGGMHLVNQFSDLIVELALAAGTTADKLRLVVLGSPGVLDPATG
HINVAPNIPGIDAINLRQVFSDRMGIPVIVENDVNLAAQGERWRGHGVETGNFAFVALGTGVGMGIIANGALLRGARGAA
GEIAYLPIGGDVFDPGGFTLGTFESAVGSVAMLRRYTGFGGRNAATVADLFAAFNAGDTSAVAAIEETARLVALAIAGIG
ATLDPELVITGGSIGARPELVNAIRGFLPRCTPYPPRIEISRFGNRAALMGGMGVAVERMHDDLFGVKLKDA

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=271, Percent_Identity=26.1992619926199, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI298566315, Length=271, Percent_Identity=26.1992619926199, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI190014632, Length=271, Percent_Identity=26.1992619926199, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4885285, Length=271, Percent_Identity=26.1992619926199, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1786891, Length=334, Percent_Identity=24.8502994011976, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787363, Length=302, Percent_Identity=27.4834437086093, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082127, Length=402, Percent_Identity=19.6517412935323, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787878, Length=240, Percent_Identity=22.0833333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790522, Length=224, Percent_Identity=29.0178571428571, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 40662; Mature: 40531

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTLSATQTPIARKISTHAVIRTVLARGSISRADIAKLTGLSKQTISDVVRDLEDDGWL
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCC
KPVGQTDGRPGRNAITYELNARAGLAVSIDLGGTKIAAAICDLLGNIIAETKVATDRRGG
CCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
MHLVNQFSDLIVELALAAGTTADKLRLVVLGSPGVLDPATGHINVAPNIPGIDAINLRQV
HHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHH
FSDRMGIPVIVENDVNLAAQGERWRGHGVETGNFAFVALGTGVGMGIIANGALLRGARGA
HHHCCCCCEEEECCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCHHEECCCEEECCCCC
AGEIAYLPIGGDVFDPGGFTLGTFESAVGSVAMLRRYTGFGGRNAATVADLFAAFNAGDT
CCCEEEEECCCCEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
SAVAAIEETARLVALAIAGIGATLDPELVITGGSIGARPELVNAIRGFLPRCTPYPPRIE
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEE
ISRFGNRAALMGGMGVAVERMHDDLFGVKLKDA
HHHCCCEEEECCCCHHHHHHHHHHHHCEEEECC
>Mature Secondary Structure 
APTLSATQTPIARKISTHAVIRTVLARGSISRADIAKLTGLSKQTISDVVRDLEDDGWL
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCC
KPVGQTDGRPGRNAITYELNARAGLAVSIDLGGTKIAAAICDLLGNIIAETKVATDRRGG
CCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
MHLVNQFSDLIVELALAAGTTADKLRLVVLGSPGVLDPATGHINVAPNIPGIDAINLRQV
HHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCCCCCCCEEECCCCCCCCCHHHHHH
FSDRMGIPVIVENDVNLAAQGERWRGHGVETGNFAFVALGTGVGMGIIANGALLRGARGA
HHHCCCCCEEEECCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCHHEECCCEEECCCCC
AGEIAYLPIGGDVFDPGGFTLGTFESAVGSVAMLRRYTGFGGRNAATVADLFAAFNAGDT
CCCEEEEECCCCEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
SAVAAIEETARLVALAIAGIGATLDPELVITGGSIGARPELVNAIRGFLPRCTPYPPRIE
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCEE
ISRFGNRAALMGGMGVAVERMHDDLFGVKLKDA
HHHCCCEEEECCCCHHHHHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8920183 [H]