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The map label for this gene is fabH [H]

Identifier: 209548800

GI number: 209548800

Start: 1207279

End: 1208274

Strand: Direct

Name: fabH [H]

Synonym: Rleg2_1197

Alternate gene names: 209548800

Gene position: 1207279-1208274 (Clockwise)

Preceding gene: 209548799

Following gene: 209548801

Centisome position: 26.6

GC content: 63.55

Gene sequence:

>996_bases
ATGAGCAATGGGGTTCAATCGAATATGATCCGTTCAGTGGTTCGCGGGTTTGGAGCCGCACTTCCGAAGCGCGTGATGAC
CAATGGTGACATGGAAGCGATCGTCGACACGTCGGACGAATGGATCGTCCAGCGCACCGGCATCCGCCAGCGTTATGTCG
CCGGTGACGACGAGACGACGGCGTCGCTCGGCGAGGCCGCCGCGCGTGCTGCCCTTGCCAATGGCGGCCTGACGCCAGCC
GATATCGATCTGATCATCTGCGCCACCTCGACGCCTGACAACACCTTTCCGGCAACCTCAGTCAACATCCAGAACCGCCT
CGGCATGAGCCACGGCTTCGCCTTCGATGTCCAGGCCGTCTGCACCGGTTTCGTCTATGCGGTCACGACGGCGGATGCCT
ATATCCGTGGCGGCCTTGCCAAGCGCGTTCTCGTCATCGGCGCGGAAACCTTTTCGCGCATTCTCGACTGGAACGACCGC
ACCACCTGCGTGCTGTTCGGCGATGGCGCCGGTGCGATCGTGCTCGAAGCGACCGAAGGCGAGGGCACCGTTGCCGATCG
TGGCGTCCTGACGGCGCATCTGCGCTCCGACGGCTCACACAAGGAAAAGCTCTATGTCGATGGCGGGCCGTCGACGACGG
GCACCGTCGGCAAGCTGCGCATGGAAGGCCGCGAGGTCTTCAAATACGCCGTCGGCATGATCACCGATGTCATTCAGGCT
GCCTTCGATTCAACCGGGACCACCGCCGAGGATCTCGACTGGCTGGTGCCGCATCAGGCCAATCGGCGCATTATCGACGG
TTCGGCCAAGAAGCTGAACATCGATGCGGCGAAGGTCGTGATCACCGTCGATCTGCACGGCAATACCTCGGCGGCCTCGA
TCCCGCTCGCCCTTGCGACCGCTGCCGGCGACGGCCGCATCAAGAAGGGCGACCTGGTGATGCTCGAAGCGATGGGCGGC
GGCTTCACCTGGGGCGCCGTTCTGCTGCGCTGGTAG

Upstream 100 bases:

>100_bases
TCGGCTACGACATGGCCAAGAACGGCCTCAATCAGAAAATAGAAAACGATCTTAAGAAATATCATGCCAAGCGGCTGCCC
CCGATGGGCCCGGAAGCTGC

Downstream 100 bases:

>100_bases
GCACGAATCCAAAAAAACTGGCGGCGAACAAGAGCTTGACCGTAAGGCGCAAGACAAATACTCTTTGCGCGATTTCACAA
AATATTTGAAATGGGCGGGG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSNGVQSNMIRSVVRGFGAALPKRVMTNGDMEAIVDTSDEWIVQRTGIRQRYVAGDDETTASLGEAAARAALANGGLTPA
DIDLIICATSTPDNTFPATSVNIQNRLGMSHGFAFDVQAVCTGFVYAVTTADAYIRGGLAKRVLVIGAETFSRILDWNDR
TTCVLFGDGAGAIVLEATEGEGTVADRGVLTAHLRSDGSHKEKLYVDGGPSTTGTVGKLRMEGREVFKYAVGMITDVIQA
AFDSTGTTAEDLDWLVPHQANRRIIDGSAKKLNIDAAKVVITVDLHGNTSAASIPLALATAAGDGRIKKGDLVMLEAMGG
GFTWGAVLLRW

Sequences:

>Translated_331_residues
MSNGVQSNMIRSVVRGFGAALPKRVMTNGDMEAIVDTSDEWIVQRTGIRQRYVAGDDETTASLGEAAARAALANGGLTPA
DIDLIICATSTPDNTFPATSVNIQNRLGMSHGFAFDVQAVCTGFVYAVTTADAYIRGGLAKRVLVIGAETFSRILDWNDR
TTCVLFGDGAGAIVLEATEGEGTVADRGVLTAHLRSDGSHKEKLYVDGGPSTTGTVGKLRMEGREVFKYAVGMITDVIQA
AFDSTGTTAEDLDWLVPHQANRRIIDGSAKKLNIDAAKVVITVDLHGNTSAASIPLALATAAGDGRIKKGDLVMLEAMGG
GFTWGAVLLRW
>Mature_330_residues
SNGVQSNMIRSVVRGFGAALPKRVMTNGDMEAIVDTSDEWIVQRTGIRQRYVAGDDETTASLGEAAARAALANGGLTPAD
IDLIICATSTPDNTFPATSVNIQNRLGMSHGFAFDVQAVCTGFVYAVTTADAYIRGGLAKRVLVIGAETFSRILDWNDRT
TCVLFGDGAGAIVLEATEGEGTVADRGVLTAHLRSDGSHKEKLYVDGGPSTTGTVGKLRMEGREVFKYAVGMITDVIQAA
FDSTGTTAEDLDWLVPHQANRRIIDGSAKKLNIDAAKVVITVDLHGNTSAASIPLALATAAGDGRIKKGDLVMLEAMGGG
FTWGAVLLRW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=317, Percent_Identity=46.3722397476341, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34881; Mature: 34750

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGVQSNMIRSVVRGFGAALPKRVMTNGDMEAIVDTSDEWIVQRTGIRQRYVAGDDETT
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCEEEECCCCCHH
ASLGEAAARAALANGGLTPADIDLIICATSTPDNTFPATSVNIQNRLGMSHGFAFDVQAV
HHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEEEEHHHHCCCCCCCEEEHHHH
CTGFVYAVTTADAYIRGGLAKRVLVIGAETFSRILDWNDRTTCVLFGDGAGAIVLEATEG
HCCCEEEEEHHHHHHHCCCHHEEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECC
EGTVADRGVLTAHLRSDGSHKEKLYVDGGPSTTGTVGKLRMEGREVFKYAVGMITDVIQA
CCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
AFDSTGTTAEDLDWLVPHQANRRIIDGSAKKLNIDAAKVVITVDLHGNTSAASIPLALAT
HHCCCCCCHHHHHEECCCCCCCEEECCCCCEEEECEEEEEEEEEECCCCCCCCCCEEEEE
AAGDGRIKKGDLVMLEAMGGGFTWGAVLLRW
ECCCCCEECCCEEEEEECCCCEEEHEEEEEC
>Mature Secondary Structure 
SNGVQSNMIRSVVRGFGAALPKRVMTNGDMEAIVDTSDEWIVQRTGIRQRYVAGDDETT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCEEEECCCCCHH
ASLGEAAARAALANGGLTPADIDLIICATSTPDNTFPATSVNIQNRLGMSHGFAFDVQAV
HHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEEEEHHHHCCCCCCCEEEHHHH
CTGFVYAVTTADAYIRGGLAKRVLVIGAETFSRILDWNDRTTCVLFGDGAGAIVLEATEG
HCCCEEEEEHHHHHHHCCCHHEEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECC
EGTVADRGVLTAHLRSDGSHKEKLYVDGGPSTTGTVGKLRMEGREVFKYAVGMITDVIQA
CCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
AFDSTGTTAEDLDWLVPHQANRRIIDGSAKKLNIDAAKVVITVDLHGNTSAASIPLALAT
HHCCCCCCHHHHHEECCCCCCCEEECCCCCEEEECEEEEEEEEEECCCCCCCCCCEEEEE
AAGDGRIKKGDLVMLEAMGGGFTWGAVLLRW
ECCCCCEECCCEEEEEECCCCEEEHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA