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The map label for this gene is ribH [H]

Identifier: 209548793

GI number: 209548793

Start: 1200861

End: 1201316

Strand: Direct

Name: ribH [H]

Synonym: Rleg2_1190

Alternate gene names: 209548793

Gene position: 1200861-1201316 (Clockwise)

Preceding gene: 209548783

Following gene: 209548794

Centisome position: 26.46

GC content: 59.87

Gene sequence:

>456_bases
ATGCCGAGAGAGACCGCTCCCCATATTTTGATCGTTGAGGCCCGCTTCTACGACGACATGGCCGATGCCCTGCTCGAAGG
CGCGATCTTCGCCTTGGAACAGGCCGGCGCCACTTTCGAGGTCGTCACCGTTCCCGGCGCACTGGAAATTCCGGCGGCGA
TTGCCATGTCGCTCGATGGAGACGACAATGGCGGAACGCATTATGATGGCTATGTCGCGCTCGGCATGGTCATTCGCGGC
GAGACCTATCACTTCGATATCGTGTCGAACGAATCCTCGCGCGCTTTGATGGATCTTGCGGTCAGCGAGTCCCTTGCCAT
CGGCAACGGCATTCTGACCGTCGAGAACGATGAACAGGCATGGGCGCGCGCGCGCCGCTCGGACAAGGACAAGGGCGGAT
TTGCCGCTCGCGCAGCTCTGACGATGATCGAGCTGAAGCAGAAACTGGGTGCATAA

Upstream 100 bases:

>100_bases
CACGTTGCGGCATCGGGCGAAAGTGCTTGCCATTCTGGTGAAGGCATGTTTTGACCGCGGGCTGCCGAGTGGAAAACGCC
CCACAAAACGAAGGTGAACC

Downstream 100 bases:

>100_bases
CGAATGAACGACGACAAGACGGAACGGCCGGTCAAGACTGCAAACCAGCGGGGCGCTGCCCGTCTTGCTGCCGTTCAGGC
ACTGTATCAGATGGATGTCG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 151; Mature: 150

Protein sequence:

>151_residues
MPRETAPHILIVEARFYDDMADALLEGAIFALEQAGATFEVVTVPGALEIPAAIAMSLDGDDNGGTHYDGYVALGMVIRG
ETYHFDIVSNESSRALMDLAVSESLAIGNGILTVENDEQAWARARRSDKDKGGFAARAALTMIELKQKLGA

Sequences:

>Translated_151_residues
MPRETAPHILIVEARFYDDMADALLEGAIFALEQAGATFEVVTVPGALEIPAAIAMSLDGDDNGGTHYDGYVALGMVIRG
ETYHFDIVSNESSRALMDLAVSESLAIGNGILTVENDEQAWARARRSDKDKGGFAARAALTMIELKQKLGA
>Mature_150_residues
PRETAPHILIVEARFYDDMADALLEGAIFALEQAGATFEVVTVPGALEIPAAIAMSLDGDDNGGTHYDGYVALGMVIRGE
TYHFDIVSNESSRALMDLAVSESLAIGNGILTVENDEQAWARARRSDKDKGGFAARAALTMIELKQKLGA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=149, Percent_Identity=40.2684563758389, Blast_Score=84, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324429, Length=117, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16143; Mature: 16012

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRETAPHILIVEARFYDDMADALLEGAIFALEQAGATFEVVTVPGALEIPAAIAMSLDG
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECC
DDNGGTHYDGYVALGMVIRGETYHFDIVSNESSRALMDLAVSESLAIGNGILTVENDEQA
CCCCCCEECCEEEEEEEEECCEEEEEEEECCCCHHHHHHHHHCCEEECCCEEEEECCHHH
WARARRSDKDKGGFAARAALTMIELKQKLGA
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRETAPHILIVEARFYDDMADALLEGAIFALEQAGATFEVVTVPGALEIPAAIAMSLDG
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECC
DDNGGTHYDGYVALGMVIRGETYHFDIVSNESSRALMDLAVSESLAIGNGILTVENDEQA
CCCCCCEECCEEEEEEEEECCEEEEEEEECCCCHHHHHHHHHCCEEECCCEEEEECCHHH
WARARRSDKDKGGFAARAALTMIELKQKLGA
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]