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The map label for this gene is pdxA [H]

Identifier: 209548667

GI number: 209548667

Start: 1081551

End: 1082579

Strand: Reverse

Name: pdxA [H]

Synonym: Rleg2_1064

Alternate gene names: 209548667

Gene position: 1082579-1081551 (Counterclockwise)

Preceding gene: 209548668

Following gene: 209548666

Centisome position: 23.86

GC content: 65.69

Gene sequence:

>1029_bases
ATGACGATACCGTTTTCGCGACCGCTTGCGCTGAGCCAGGGCGACCCCGCCGGCATCGGGCCGGATATTACGCTGATGGC
CTGGCTCCGGCGGCGTGAACTCGGGCTGCCGCCTTTCTTCTTGATCGGCGATCCCGATGTGTTGGCGTTGCGAGCCCGCC
AGCTCAACCTTTCGGTTTCGATCCGCGAGACGGATAAAGCCAGCGAGGCTGCTGGCATGTTTGCCGATGCGCTACCCGTC
ATGACGGTGCCTGCCGGTATCGAGGTGGTTGCCGGCGAGCCGCATGCGGCAACGGCGAAGGGCACGATCGCAGCGATCGA
AAAAGCCGTGTCGCTTGTCATCACCGGCGAGGCGCTCGCGGTCGTCACCAACCCGATTGCCAAATCAGTGCTCTACGAGG
CCGGTTTCCGGTTTCCCGGCCATACAGAATTTCTCGCTGATCTCGCCGCCAGGGCGACCGGCAGGCCGGTGACGCCTGTC
ATGATGCTGTCAGGGCCGAAGCTTCGAGCCATTCCCGTCACCATCCACATTCCGGTCAGGGACGTGCCGCAGGCGCTGAC
CGGCGAACTGATCGCGGAAACCTGCCGGATCGCCCATGAAGATCTCAGGCAGCGCTTCGGCATCGCGGCGCCGCGGCTCG
CGGTTGCCGGTTTGAACCCGCATGCGGGCGAAGGCGGGTCGATCGGCAGGGAGGACGAGGATGTCATCCGTCCGGCGATC
CAGCGCCTGCGCGACGAGGGCATCGATGCGATCGGCCCCCTGCCCGCCGACACGATGTTCCATGACGAGGCGCGGGCGCG
ATATGACGTCGCCGTCTGCATGTATCACGATCAGGCGCTGATCCCAGCCAAGGCGCTCGGTTTCGACGACAGCGTCAACG
TCACGCTCGGGCTTCCCTTCGTGCGCACCTCGCCGGATCACGGCACCGCTTTCGGCATCGCCGGCAAGGGACTGGCTCGC
GAACAGAGCCTGGTTGCAGCGCTGAAGCTCGCCGCCCAGCTCGGCCGCACTGCGGAAAGCCACCGCTGA

Upstream 100 bases:

>100_bases
GGCCAAGGGTGGCAAGGACGCCAGCCCGGAAAACGAAAACAGCAAGAAGTACCTGGATGAACTGCGCAAAAAGGCGCAGA
TCGCCTATCGCTGACCTGCG

Downstream 100 bases:

>100_bases
TGGCAGCACTCGATGGCCTGCCGCCGCTTCGCGACGTCATCCAGCGTCACGGCCTCGATGCGCGCAAGGCGCTCGGGCAG
AACTTCCTGCTCGACCTTAA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTIPFSRPLALSQGDPAGIGPDITLMAWLRRRELGLPPFFLIGDPDVLALRARQLNLSVSIRETDKASEAAGMFADALPV
MTVPAGIEVVAGEPHAATAKGTIAAIEKAVSLVITGEALAVVTNPIAKSVLYEAGFRFPGHTEFLADLAARATGRPVTPV
MMLSGPKLRAIPVTIHIPVRDVPQALTGELIAETCRIAHEDLRQRFGIAAPRLAVAGLNPHAGEGGSIGREDEDVIRPAI
QRLRDEGIDAIGPLPADTMFHDEARARYDVAVCMYHDQALIPAKALGFDDSVNVTLGLPFVRTSPDHGTAFGIAGKGLAR
EQSLVAALKLAAQLGRTAESHR

Sequences:

>Translated_342_residues
MTIPFSRPLALSQGDPAGIGPDITLMAWLRRRELGLPPFFLIGDPDVLALRARQLNLSVSIRETDKASEAAGMFADALPV
MTVPAGIEVVAGEPHAATAKGTIAAIEKAVSLVITGEALAVVTNPIAKSVLYEAGFRFPGHTEFLADLAARATGRPVTPV
MMLSGPKLRAIPVTIHIPVRDVPQALTGELIAETCRIAHEDLRQRFGIAAPRLAVAGLNPHAGEGGSIGREDEDVIRPAI
QRLRDEGIDAIGPLPADTMFHDEARARYDVAVCMYHDQALIPAKALGFDDSVNVTLGLPFVRTSPDHGTAFGIAGKGLAR
EQSLVAALKLAAQLGRTAESHR
>Mature_341_residues
TIPFSRPLALSQGDPAGIGPDITLMAWLRRRELGLPPFFLIGDPDVLALRARQLNLSVSIRETDKASEAAGMFADALPVM
TVPAGIEVVAGEPHAATAKGTIAAIEKAVSLVITGEALAVVTNPIAKSVLYEAGFRFPGHTEFLADLAARATGRPVTPVM
MLSGPKLRAIPVTIHIPVRDVPQALTGELIAETCRIAHEDLRQRFGIAAPRLAVAGLNPHAGEGGSIGREDEDVIRPAIQ
RLRDEGIDAIGPLPADTMFHDEARARYDVAVCMYHDQALIPAKALGFDDSVNVTLGLPFVRTSPDHGTAFGIAGKGLARE
QSLVAALKLAAQLGRTAESHR

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=329, Percent_Identity=40.4255319148936, Blast_Score=226, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36201; Mature: 36070

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIPFSRPLALSQGDPAGIGPDITLMAWLRRRELGLPPFFLIGDPDVLALRARQLNLSVS
CCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEEEEEE
IRETDKASEAAGMFADALPVMTVPAGIEVVAGEPHAATAKGTIAAIEKAVSLVITGEALA
EECCCCHHHHHHHHHHCCCCEECCCCCEEEECCCCCCCCCHHHHHHHHHHEEEECCCEEE
VVTNPIAKSVLYEAGFRFPGHTEFLADLAARATGRPVTPVMMLSGPKLRAIPVTIHIPVR
EHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEEECHH
DVPQALTGELIAETCRIAHEDLRQRFGIAAPRLAVAGLNPHAGEGGSIGREDEDVIRPAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
QRLRDEGIDAIGPLPADTMFHDEARARYDVAVCMYHDQALIPAKALGFDDSVNVTLGLPF
HHHHHCCCCCCCCCCCCHHCCHHHHCEEEEEEEEECCCCCCCHHHCCCCCCCEEEEECCE
VRTSPDHGTAFGIAGKGLAREQSLVAALKLAAQLGRTAESHR
EEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
TIPFSRPLALSQGDPAGIGPDITLMAWLRRRELGLPPFFLIGDPDVLALRARQLNLSVS
CCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEEEEEE
IRETDKASEAAGMFADALPVMTVPAGIEVVAGEPHAATAKGTIAAIEKAVSLVITGEALA
EECCCCHHHHHHHHHHCCCCEECCCCCEEEECCCCCCCCCHHHHHHHHHHEEEECCCEEE
VVTNPIAKSVLYEAGFRFPGHTEFLADLAARATGRPVTPVMMLSGPKLRAIPVTIHIPVR
EHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEEECHH
DVPQALTGELIAETCRIAHEDLRQRFGIAAPRLAVAGLNPHAGEGGSIGREDEDVIRPAI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
QRLRDEGIDAIGPLPADTMFHDEARARYDVAVCMYHDQALIPAKALGFDDSVNVTLGLPF
HHHHHCCCCCCCCCCCCHHCCHHHHCEEEEEEEEECCCCCCCHHHCCCCCCCEEEEECCE
VRTSPDHGTAFGIAGKGLAREQSLVAALKLAAQLGRTAESHR
EEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]