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The map label for this gene is fabD [H]

Identifier: 209548659

GI number: 209548659

Start: 1074140

End: 1075084

Strand: Direct

Name: fabD [H]

Synonym: Rleg2_1056

Alternate gene names: 209548659

Gene position: 1074140-1075084 (Clockwise)

Preceding gene: 209548652

Following gene: 209548660

Centisome position: 23.67

GC content: 64.76

Gene sequence:

>945_bases
ATGACCATTGCTTTCACTTTTCCCGGTCAGGGCAGTCAGGCCGTCGGCATGGGCAAGGATCTGGCCGAGAATTTCGCGGA
AGCCCGCGCCGTTTTCGACGAGGTCGATGAGGCGCTCGGTGAAAAGCTTTCCGACGTCATGTTCAACGGTCCCGAGGAGA
CCTTGACCCTGACGGCGAACGCCCAGCCGGCGCTGATGGCCGTCTCGATCGCCGTCGTCCGCATTCTTGAGGCCAAGGGA
CTGGATCTGAAGTCCAAGGTCGCCTATGTCGCCGGCCACTCGCTCGGCGAATATTCTGCCCTTTGCGCAGCCGGTACGTT
CTCGCTCGCTGATACCGCCCGGCTGCTGCGCATCCGCGGCAACGCCATGCAGGCGGCCGTCCCCGTCGGCGTCGGCGCCA
TGGCTGCGATCATCGGTCTCGAACATGCCGATGTCGTTGCCGTCTGCGAAGAGGCTGCGGCAACCGGCGCATGCCAGATC
GCCAATGACAATGGCGGCGGCCAGATCGTCATTTCGGGCGAGAAGGCAGCCGTCGAAAAGGCCGCGGGACTCGCCACCGA
CAAGGGCGCCAAGCGCGCCATCCTGCTGCCGGTCTCCGCACCCTTCCATTCCAAGCTGATGGCGCCTGCCGCCGACGCCA
TGCGCGAAGCACTGGCAAAGGTCGCCAAATCAGATCCCGTCGTGCCCGTCATTGCCAATGTCCGCGCCGCGCCCGTAACC
ACAGCCGACGAGATCGCCAGCTTGCTGGTCGAGCAGGTGACCGGTCAGGTCCGCTGGCGCGAGACGGTGGAATGGTTCGC
TGGCAATGGCGTGACGACGCTTTATGAACTCGGCTCCGGCAAGGTGCTGACCGGCCTTGCCCGGCGCATCGACAAGACGA
TCAACGGCATCTCCGTCAACGGTCCGGCGGATATCGACGCGGCCGTTGCCGCCCTCATGGCCTGA

Upstream 100 bases:

>100_bases
CGGAGAATAAGCCGCCACTTGACTCTGCCGGAAAGAATGTCAATTGGAGGCAAAACAGCCTCAAGGGGCGCAATCAGGGG
CAAGAGCCAGGGACACGAGA

Downstream 100 bases:

>100_bases
TTGCTATCTCCAGATATAAGGAACGCTTCCATGCTCGATCTTTCTGGCCGCAAGGCTCTCGTCACCGGCGCATCGGGCGG
TATCGGCGAGGAAATCGCCC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTIAFTFPGQGSQAVGMGKDLAENFAEARAVFDEVDEALGEKLSDVMFNGPEETLTLTANAQPALMAVSIAVVRILEAKG
LDLKSKVAYVAGHSLGEYSALCAAGTFSLADTARLLRIRGNAMQAAVPVGVGAMAAIIGLEHADVVAVCEEAAATGACQI
ANDNGGGQIVISGEKAAVEKAAGLATDKGAKRAILLPVSAPFHSKLMAPAADAMREALAKVAKSDPVVPVIANVRAAPVT
TADEIASLLVEQVTGQVRWRETVEWFAGNGVTTLYELGSGKVLTGLARRIDKTINGISVNGPADIDAAVAALMA

Sequences:

>Translated_314_residues
MTIAFTFPGQGSQAVGMGKDLAENFAEARAVFDEVDEALGEKLSDVMFNGPEETLTLTANAQPALMAVSIAVVRILEAKG
LDLKSKVAYVAGHSLGEYSALCAAGTFSLADTARLLRIRGNAMQAAVPVGVGAMAAIIGLEHADVVAVCEEAAATGACQI
ANDNGGGQIVISGEKAAVEKAAGLATDKGAKRAILLPVSAPFHSKLMAPAADAMREALAKVAKSDPVVPVIANVRAAPVT
TADEIASLLVEQVTGQVRWRETVEWFAGNGVTTLYELGSGKVLTGLARRIDKTINGISVNGPADIDAAVAALMA
>Mature_313_residues
TIAFTFPGQGSQAVGMGKDLAENFAEARAVFDEVDEALGEKLSDVMFNGPEETLTLTANAQPALMAVSIAVVRILEAKGL
DLKSKVAYVAGHSLGEYSALCAAGTFSLADTARLLRIRGNAMQAAVPVGVGAMAAIIGLEHADVVAVCEEAAATGACQIA
NDNGGGQIVISGEKAAVEKAAGLATDKGAKRAILLPVSAPFHSKLMAPAADAMREALAKVAKSDPVVPVIANVRAAPVTT
ADEIASLLVEQVTGQVRWRETVEWFAGNGVTTLYELGSGKVLTGLARRIDKTINGISVNGPADIDAAVAALMA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=289, Percent_Identity=31.8339100346021, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI27477045, Length=105, Percent_Identity=38.0952380952381, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=46.5798045602606, Blast_Score=242, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=27.6450511945392, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=290, Percent_Identity=28.9655172413793, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24665753, Length=312, Percent_Identity=32.6923076923077, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32137; Mature: 32006

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAFTFPGQGSQAVGMGKDLAENFAEARAVFDEVDEALGEKLSDVMFNGPEETLTLTAN
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
AQPALMAVSIAVVRILEAKGLDLKSKVAYVAGHSLGEYSALCAAGTFSLADTARLLRIRG
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCC
NAMQAAVPVGVGAMAAIIGLEHADVVAVCEEAAATGACQIANDNGGGQIVISGEKAAVEK
CCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEECCHHHHHH
AAGLATDKGAKRAILLPVSAPFHSKLMAPAADAMREALAKVAKSDPVVPVIANVRAAPVT
HHCCCCCCCCCEEEEEEECCCHHHHHHCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
TADEIASLLVEQVTGQVRWRETVEWFAGNGVTTLYELGSGKVLTGLARRIDKTINGISVN
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCEECC
GPADIDAAVAALMA
CCCCHHHHHHHHCC
>Mature Secondary Structure 
TIAFTFPGQGSQAVGMGKDLAENFAEARAVFDEVDEALGEKLSDVMFNGPEETLTLTAN
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
AQPALMAVSIAVVRILEAKGLDLKSKVAYVAGHSLGEYSALCAAGTFSLADTARLLRIRG
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHCC
NAMQAAVPVGVGAMAAIIGLEHADVVAVCEEAAATGACQIANDNGGGQIVISGEKAAVEK
CCHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEECCHHHHHH
AAGLATDKGAKRAILLPVSAPFHSKLMAPAADAMREALAKVAKSDPVVPVIANVRAAPVT
HHCCCCCCCCCEEEEEEECCCHHHHHHCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
TADEIASLLVEQVTGQVRWRETVEWFAGNGVTTLYELGSGKVLTGLARRIDKTINGISVN
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCEECC
GPADIDAAVAALMA
CCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]