Click here to switch to the map view.

The map label for this gene is alr [H]

Identifier: 209548649

GI number: 209548649

Start: 1064837

End: 1066003

Strand: Reverse

Name: alr [H]

Synonym: Rleg2_1046

Alternate gene names: 209548649

Gene position: 1066003-1064837 (Counterclockwise)

Preceding gene: 209548653

Following gene: 209548647

Centisome position: 23.49

GC content: 64.44

Gene sequence:

>1167_bases
ATGACAGATTTTCCTATTCCCTTCGAAGACGACGATCTTTTTGCTTCCGCGGGCCTGCGGCTGACCGTCGATCTGACCGC
GCTGACGGAGAACTGGCGCGACATGGCGCAACGCTCCGGTGCGGCGCGTGCTGCTGCCGTCGTCAAGGCGGATGCCTATG
GCATGGGCATCGAGGATGCCGGTGAAGCGCTCTATATGGCAGGCGCCCGCGACTTCTTCGTTGCGACCGTCGACGAGGGC
GTGACACTTCGCCTCTATGCGCCGGACGCCCGCATCTTCGTCCTGTCAGGCATATGGCCGGGCACCGAGCGGCGCTTCTT
CGAAAACGATCTGGTGCCGGTGATTTCCTCCGACGAGCAGCTCGCCTTCTGGATGGCGGTGCTTGCCGATTACGGCGATT
ACCCCTGCGCACTGCATGTCGATACCGGCTTCAACCGGCTCGGACTGCATATGGACGATGCGATTGCACTCGCCGACGAC
GTTTCGCGGCCGGCGAGCTTTGCGCCGGTGCTTGTGATGAGCCATCTCGCCTGCGGCGACGAGCCCAGCCATGCGATGAA
CCGGCAGCAGCTCGAATCATTCCGCAGGGTTAGCGCCGCCTATGAAGGTATCGATTCAAGCCTTGCCGCCTCGGCCGGCA
TTTTCCTTGGCGAGGATTATCACTTCGACCTGACCCGTCCCGGCATCGCGCTTTATGGCGGCGAAGCGGTCTGCGGCCTG
GCCAATCCGATGCGGCCTGTGGCAACCGCGGAAGCGCGCATCATCCAGGTGCGCAGCGTCGAGGCCGGCGAGACCGTCAG
CTATGGGCGCGCGCTGCAGCTTCGCCGCAAAAGCCGGCTGGCGATCGCTTCGGCCGGCTATGCCGACGGTTACATGCGCG
GGCTGTCGAGCGGCGGCGTGCCGCTGCGCCAGGCCGTGCCGCAGGGCGGGCAAGGCTTCATCGCCGGACACAAGGTACCG
GTCGCCGGCCGGATCACCATGGACCTGACGATCTTCGATATCACCGACCTGCCCGACAACGCGGTGCGCGCCGGCGATTA
TGTCGAGTTGTTCGGAAAGAATATGCCCCTGGACGACGTGGCGCGGGCGGCGGGCACGATCGGATATGAAATCCTGACCA
GCATGGGGCTGCGCCACGAACGGCGCTATGTCGCCGACGAGGAATAG

Upstream 100 bases:

>100_bases
AGAAGCAAAGGGTGGTATGTGGCTGCCTGCGCTTTCCCTTAACCGCAATGCTCTCTAGACTGGTCCCAAGCGGTTTCCTT
CCACTATTTCACGGCGATTC

Downstream 100 bases:

>100_bases
CTTCCCCGTCAGCGGCTGCTGAGCGCCAGCCGGACACCGAGCGCCAGGAAAAGCGCGCCGAGGCCGCGATCGAGCCATAG
CCCGATTTTTTGATTATGCC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTDFPIPFEDDDLFASAGLRLTVDLTALTENWRDMAQRSGAARAAAVVKADAYGMGIEDAGEALYMAGARDFFVATVDEG
VTLRLYAPDARIFVLSGIWPGTERRFFENDLVPVISSDEQLAFWMAVLADYGDYPCALHVDTGFNRLGLHMDDAIALADD
VSRPASFAPVLVMSHLACGDEPSHAMNRQQLESFRRVSAAYEGIDSSLAASAGIFLGEDYHFDLTRPGIALYGGEAVCGL
ANPMRPVATAEARIIQVRSVEAGETVSYGRALQLRRKSRLAIASAGYADGYMRGLSSGGVPLRQAVPQGGQGFIAGHKVP
VAGRITMDLTIFDITDLPDNAVRAGDYVELFGKNMPLDDVARAAGTIGYEILTSMGLRHERRYVADEE

Sequences:

>Translated_388_residues
MTDFPIPFEDDDLFASAGLRLTVDLTALTENWRDMAQRSGAARAAAVVKADAYGMGIEDAGEALYMAGARDFFVATVDEG
VTLRLYAPDARIFVLSGIWPGTERRFFENDLVPVISSDEQLAFWMAVLADYGDYPCALHVDTGFNRLGLHMDDAIALADD
VSRPASFAPVLVMSHLACGDEPSHAMNRQQLESFRRVSAAYEGIDSSLAASAGIFLGEDYHFDLTRPGIALYGGEAVCGL
ANPMRPVATAEARIIQVRSVEAGETVSYGRALQLRRKSRLAIASAGYADGYMRGLSSGGVPLRQAVPQGGQGFIAGHKVP
VAGRITMDLTIFDITDLPDNAVRAGDYVELFGKNMPLDDVARAAGTIGYEILTSMGLRHERRYVADEE
>Mature_387_residues
TDFPIPFEDDDLFASAGLRLTVDLTALTENWRDMAQRSGAARAAAVVKADAYGMGIEDAGEALYMAGARDFFVATVDEGV
TLRLYAPDARIFVLSGIWPGTERRFFENDLVPVISSDEQLAFWMAVLADYGDYPCALHVDTGFNRLGLHMDDAIALADDV
SRPASFAPVLVMSHLACGDEPSHAMNRQQLESFRRVSAAYEGIDSSLAASAGIFLGEDYHFDLTRPGIALYGGEAVCGLA
NPMRPVATAEARIIQVRSVEAGETVSYGRALQLRRKSRLAIASAGYADGYMRGLSSGGVPLRQAVPQGGQGFIAGHKVPV
AGRITMDLTIFDITDLPDNAVRAGDYVELFGKNMPLDDVARAAGTIGYEILTSMGLRHERRYVADEE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=33.6043360433604, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1790487, Length=380, Percent_Identity=31.5789473684211, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41889; Mature: 41758

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFPIPFEDDDLFASAGLRLTVDLTALTENWRDMAQRSGAARAAAVVKADAYGMGIEDA
CCCCCCCCCCCCHHHCCCCEEEEEEHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCC
GEALYMAGARDFFVATVDEGVTLRLYAPDARIFVLSGIWPGTERRFFENDLVPVISSDEQ
CCEEEEECCCEEEEEEECCCEEEEEECCCCEEEEEECCCCCCCCHHHCCCCEEEECCCCH
LAFWMAVLADYGDYPCALHVDTGFNRLGLHMDDAIALADDVSRPASFAPVLVMSHLACGD
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCC
EPSHAMNRQQLESFRRVSAAYEGIDSSLAASAGIFLGEDYHFDLTRPGIALYGGEAVCGL
CCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHCCEEECCCEEEECCCCCEEEECCCEEECC
ANPMRPVATAEARIIQVRSVEAGETVSYGRALQLRRKSRLAIASAGYADGYMRGLSSGGV
CCCCCCHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCCC
PLRQAVPQGGQGFIAGHKVPVAGRITMDLTIFDITDLPDNAVRAGDYVELFGKNMPLDDV
CHHHHCCCCCCEEEECCCCCEEEEEEEEEEEEEECCCCCCHHCCCCHHHHHCCCCCHHHH
ARAAGTIGYEILTSMGLRHERRYVADEE
HHHHHHHHHHHHHHHCCCHHHCCCCCCC
>Mature Secondary Structure 
TDFPIPFEDDDLFASAGLRLTVDLTALTENWRDMAQRSGAARAAAVVKADAYGMGIEDA
CCCCCCCCCCCHHHCCCCEEEEEEHHHHHHHHHHHHHCCCHHHEEEEEECCCCCCCCCC
GEALYMAGARDFFVATVDEGVTLRLYAPDARIFVLSGIWPGTERRFFENDLVPVISSDEQ
CCEEEEECCCEEEEEEECCCEEEEEECCCCEEEEEECCCCCCCCHHHCCCCEEEECCCCH
LAFWMAVLADYGDYPCALHVDTGFNRLGLHMDDAIALADDVSRPASFAPVLVMSHLACGD
HHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCC
EPSHAMNRQQLESFRRVSAAYEGIDSSLAASAGIFLGEDYHFDLTRPGIALYGGEAVCGL
CCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHCCEEECCCEEEECCCCCEEEECCCEEECC
ANPMRPVATAEARIIQVRSVEAGETVSYGRALQLRRKSRLAIASAGYADGYMRGLSSGGV
CCCCCCHHCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCCC
PLRQAVPQGGQGFIAGHKVPVAGRITMDLTIFDITDLPDNAVRAGDYVELFGKNMPLDDV
CHHHHCCCCCCEEEECCCCCEEEEEEEEEEEEEECCCCCCHHCCCCHHHHHCCCCCHHHH
ARAAGTIGYEILTSMGLRHERRYVADEE
HHHHHHHHHHHHHHHCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]