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The map label for this gene is iolC [H]

Identifier: 209548585

GI number: 209548585

Start: 1002083

End: 1004017

Strand: Reverse

Name: iolC [H]

Synonym: Rleg2_0982

Alternate gene names: 209548585

Gene position: 1004017-1002083 (Counterclockwise)

Preceding gene: 209548586

Following gene: 209548584

Centisome position: 22.12

GC content: 64.24

Gene sequence:

>1935_bases
ATGGTACAATCGAATCCGGGTTCACGGCCGGAGCCGGCGCTTGATGTAATCACCATCGGCCGCTCCTCGGTCGATCTTTA
CGGACAGCAGATCGGTTCGCGGCTGGAGGATATCGGCTCCTTCGCTAAATCAGTCGGCGGCTGCCCGGCCAATATCGCCA
TCGGCACGGCGCGGCTCGGCCTCAAATCCGGCCTCATCACTCGCGTCGGCGACGAGCAGATGGGGCGCTTCATCCGCGAG
CAGTCGGCGCGCGAGGGCGTGGCAACAGATGGCATCGCCACCGACAAGGAGCGGCTGACGGCGCTGGTGCTCCTTGCGGT
CGAGGCCGAGGGCGTATCGCCGATGATCTTCTATCGCTCCGACTGCGCCGACATGGCGCTCGACGAAGGCGATATCGACG
AGAATTTCATCCGCTCGTCGCGCGCCGTGCTGGTTTCCGGCACGCATTTCTCCAGGCCGAATACCGAGGCCGCGCAGCGC
AAGGCGATCCGCATCGCCAAGGCGAACGGCTGCAAGGTGATCTTCGACATCGACTACCGGCCGAACCTCTGGGGCCTTGC
CGGCCATGCCGAAGGTTTCGAGCGCTACGTGAAATCCGACCGTGTTTCCTCGAAGATGAAGGAGACGCTGCCGGATTGCG
ACCTCATCGTCGGTACCGAAGAAGAAATCCTGATCGCTTCCGGCGCCGACGATGTGCTCGGCGCACTGAAGGAGATTCGC
CGCCTGTCGCCGGCGACGATCGTGCTCAAGCGCGGCGCCATGGGCTGCATCGTCTATGACGGGCCGATCGCCGACGACCT
CGAAGCCGGCATCGTCGGCGAGGGTTTTCCGATCGAAGTCTTCAACGTGCTCGGCGCCGGCGATGCCTTCATGTCCGGCT
TCCTGCGCGGCTTTCTACGCGACGAGCCGCTGAAGACCTGCGCCACCTGGGCCAATGCCTGCGGCGCCTTCGCCGTCTCC
CGGCTGCTCTGCTCGCCGGAATATCCGACCTGGGCGGAGCTCGACTACTTCCTGAAGACCGGCAGCCAGCATCGGGCGCT
GCGCAAGGACGAGGCGATCAACCATATCCACTGGGCATCGACCCGGCGCGGCGAAATCCCGCTGCTGATGGCGCTGGCGA
TCGACCACCGTTCGCAGCTCGTCAGCGTCGCCGATGAGCTCGGCGTCGGCCATGAGAAGATCGTCGCCTTCAAGCGGCTG
GCGGTCTCTGCAGCGGCGCGGGTTTCGAATGGCCGTGACGGCTACGGCATGCTGATCGACGAACGTTTCGGCCGCGACGC
CTTCTTCGATGCGGCGACGAAGAATTTTTCCTGGATCGGCCGGCCGGTAGAGCTGCCGGGCTCGAAGCCACTGCGTTTCG
AATTCAGCCAGGATATCGGCTCGCAGCTGGTGGAATGGCCGCTCGGCCATTGCATCAAGTGCCTGTGCTTCTACCATCCC
GACGATCCGGCCGAATTGAAGAGCGAGCAGCAGGAGAAGCTGCGCACCCTGTTCGAGGCCGCCCGCAAGGTCGGGCGCGA
GCTGCTGGTGGAAATCATCGCCGGCAAGAACGGACCGCTGACCGACGATACGATCGCCACCGCGCTGGAAGAACTATATG
CGCTCGGCATCAAGCCGGACTGGTGGAAGCTCGAGCCGCAGGCATCGAGCGAAGCCTGGAAGAAGATCGATGCGGTGATT
GCCAAAAATGATCCATGGTGCCGCGGTATCGTGCTTTTGGGGCTCGAAGCGCCCGCCGACGAGCTGATCTCCTGCTTCGA
GGCGACGCTGGCTGCCCCTTCCGTGAAGGGCTTTGCCGTCGGCCGGACCATCTTTGCCGATGCGGCGCGCGCCTGGCTTT
CGGGCGCAATGAACGACGAGGAAGCGATCGCCGACATGGCCGGCCGCTTCCGGCAGCTGACAGAGGCGTGGCTGAAGACG
CGCGACCGTCAGTAG

Upstream 100 bases:

>100_bases
GGAATAAACATTCCGAATTGACAAAATATCGGAACCGATGTTTCATTATTCACAAATTCGCAGGCACTGGAAGCCGCGCA
AAATCTAGCGGGAGGACATC

Downstream 100 bases:

>100_bases
GAAATAGGAAAAAGACCCCTCCCCAACCCCTCCCCACAAGGGGGAGGGCCTTAACTTGAGGCACCGCCTCCGCCATGAGT
AAGCATCCTGCGGATGAAAC

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MVQSNPGSRPEPALDVITIGRSSVDLYGQQIGSRLEDIGSFAKSVGGCPANIAIGTARLGLKSGLITRVGDEQMGRFIRE
QSAREGVATDGIATDKERLTALVLLAVEAEGVSPMIFYRSDCADMALDEGDIDENFIRSSRAVLVSGTHFSRPNTEAAQR
KAIRIAKANGCKVIFDIDYRPNLWGLAGHAEGFERYVKSDRVSSKMKETLPDCDLIVGTEEEILIASGADDVLGALKEIR
RLSPATIVLKRGAMGCIVYDGPIADDLEAGIVGEGFPIEVFNVLGAGDAFMSGFLRGFLRDEPLKTCATWANACGAFAVS
RLLCSPEYPTWAELDYFLKTGSQHRALRKDEAINHIHWASTRRGEIPLLMALAIDHRSQLVSVADELGVGHEKIVAFKRL
AVSAAARVSNGRDGYGMLIDERFGRDAFFDAATKNFSWIGRPVELPGSKPLRFEFSQDIGSQLVEWPLGHCIKCLCFYHP
DDPAELKSEQQEKLRTLFEAARKVGRELLVEIIAGKNGPLTDDTIATALEELYALGIKPDWWKLEPQASSEAWKKIDAVI
AKNDPWCRGIVLLGLEAPADELISCFEATLAAPSVKGFAVGRTIFADAARAWLSGAMNDEEAIADMAGRFRQLTEAWLKT
RDRQ

Sequences:

>Translated_644_residues
MVQSNPGSRPEPALDVITIGRSSVDLYGQQIGSRLEDIGSFAKSVGGCPANIAIGTARLGLKSGLITRVGDEQMGRFIRE
QSAREGVATDGIATDKERLTALVLLAVEAEGVSPMIFYRSDCADMALDEGDIDENFIRSSRAVLVSGTHFSRPNTEAAQR
KAIRIAKANGCKVIFDIDYRPNLWGLAGHAEGFERYVKSDRVSSKMKETLPDCDLIVGTEEEILIASGADDVLGALKEIR
RLSPATIVLKRGAMGCIVYDGPIADDLEAGIVGEGFPIEVFNVLGAGDAFMSGFLRGFLRDEPLKTCATWANACGAFAVS
RLLCSPEYPTWAELDYFLKTGSQHRALRKDEAINHIHWASTRRGEIPLLMALAIDHRSQLVSVADELGVGHEKIVAFKRL
AVSAAARVSNGRDGYGMLIDERFGRDAFFDAATKNFSWIGRPVELPGSKPLRFEFSQDIGSQLVEWPLGHCIKCLCFYHP
DDPAELKSEQQEKLRTLFEAARKVGRELLVEIIAGKNGPLTDDTIATALEELYALGIKPDWWKLEPQASSEAWKKIDAVI
AKNDPWCRGIVLLGLEAPADELISCFEATLAAPSVKGFAVGRTIFADAARAWLSGAMNDEEAIADMAGRFRQLTEAWLKT
RDRQ
>Mature_644_residues
MVQSNPGSRPEPALDVITIGRSSVDLYGQQIGSRLEDIGSFAKSVGGCPANIAIGTARLGLKSGLITRVGDEQMGRFIRE
QSAREGVATDGIATDKERLTALVLLAVEAEGVSPMIFYRSDCADMALDEGDIDENFIRSSRAVLVSGTHFSRPNTEAAQR
KAIRIAKANGCKVIFDIDYRPNLWGLAGHAEGFERYVKSDRVSSKMKETLPDCDLIVGTEEEILIASGADDVLGALKEIR
RLSPATIVLKRGAMGCIVYDGPIADDLEAGIVGEGFPIEVFNVLGAGDAFMSGFLRGFLRDEPLKTCATWANACGAFAVS
RLLCSPEYPTWAELDYFLKTGSQHRALRKDEAINHIHWASTRRGEIPLLMALAIDHRSQLVSVADELGVGHEKIVAFKRL
AVSAAARVSNGRDGYGMLIDERFGRDAFFDAATKNFSWIGRPVELPGSKPLRFEFSQDIGSQLVEWPLGHCIKCLCFYHP
DDPAELKSEQQEKLRTLFEAARKVGRELLVEIIAGKNGPLTDDTIATALEELYALGIKPDWWKLEPQASSEAWKKIDAVI
AKNDPWCRGIVLLGLEAPADELISCFEATLAAPSVKGFAVGRTIFADAARAWLSGAMNDEEAIADMAGRFRQLTEAWLKT
RDRQ

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=323, Percent_Identity=25.6965944272446, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 70338; Mature: 70338

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQSNPGSRPEPALDVITIGRSSVDLYGQQIGSRLEDIGSFAKSVGGCPANIAIGTARLG
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHH
LKSGLITRVGDEQMGRFIREQSAREGVATDGIATDKERLTALVLLAVEAEGVSPMIFYRS
HHCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEEEECCCCCEEEEEEC
DCADMALDEGDIDENFIRSSRAVLVSGTHFSRPNTEAAQRKAIRIAKANGCKVIFDIDYR
CHHHHCCCCCCCCHHHHHCCCEEEEECCCCCCCCHHHHHHHHHEEEECCCCEEEEEECCC
PNLWGLAGHAEGFERYVKSDRVSSKMKETLPDCDLIVGTEEEILIASGADDVLGALKEIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCHHHHHHHHHHH
RLSPATIVLKRGAMGCIVYDGPIADDLEAGIVGEGFPIEVFNVLGAGDAFMSGFLRGFLR
HCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHC
DEPLKTCATWANACGAFAVSRLLCSPEYPTWAELDYFLKTGSQHRALRKDEAINHIHWAS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCHHEECC
TRRGEIPLLMALAIDHRSQLVSVADELGVGHEKIVAFKRLAVSAAARVSNGRDGYGMLID
CCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ERFGRDAFFDAATKNFSWIGRPVELPGSKPLRFEFSQDIGSQLVEWPLGHCIKCLCFYHP
HHCCCHHHHHHHCCCCHHCCCCEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEECC
DDPAELKSEQQEKLRTLFEAARKVGRELLVEIIAGKNGPLTDDTIATALEELYALGIKPD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
WWKLEPQASSEAWKKIDAVIAKNDPWCRGIVLLGLEAPADELISCFEATLAAPSVKGFAV
CEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHH
GRTIFADAARAWLSGAMNDEEAIADMAGRFRQLTEAWLKTRDRQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVQSNPGSRPEPALDVITIGRSSVDLYGQQIGSRLEDIGSFAKSVGGCPANIAIGTARLG
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHH
LKSGLITRVGDEQMGRFIREQSAREGVATDGIATDKERLTALVLLAVEAEGVSPMIFYRS
HHCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHEEEEECCCCCEEEEEEC
DCADMALDEGDIDENFIRSSRAVLVSGTHFSRPNTEAAQRKAIRIAKANGCKVIFDIDYR
CHHHHCCCCCCCCHHHHHCCCEEEEECCCCCCCCHHHHHHHHHEEEECCCCEEEEEECCC
PNLWGLAGHAEGFERYVKSDRVSSKMKETLPDCDLIVGTEEEILIASGADDVLGALKEIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCHHHHHHHHHHH
RLSPATIVLKRGAMGCIVYDGPIADDLEAGIVGEGFPIEVFNVLGAGDAFMSGFLRGFLR
HCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHC
DEPLKTCATWANACGAFAVSRLLCSPEYPTWAELDYFLKTGSQHRALRKDEAINHIHWAS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCHHEECC
TRRGEIPLLMALAIDHRSQLVSVADELGVGHEKIVAFKRLAVSAAARVSNGRDGYGMLID
CCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ERFGRDAFFDAATKNFSWIGRPVELPGSKPLRFEFSQDIGSQLVEWPLGHCIKCLCFYHP
HHCCCHHHHHHHCCCCHHCCCCEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEECC
DDPAELKSEQQEKLRTLFEAARKVGRELLVEIIAGKNGPLTDDTIATALEELYALGIKPD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
WWKLEPQASSEAWKKIDAVIAKNDPWCRGIVLLGLEAPADELISCFEATLAAPSVKGFAV
CEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHH
GRTIFADAARAWLSGAMNDEEAIADMAGRFRQLTEAWLKTRDRQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA