Click here to switch to the map view.

The map label for this gene is gstA [H]

Identifier: 209548513

GI number: 209548513

Start: 925983

End: 926594

Strand: Direct

Name: gstA [H]

Synonym: Rleg2_0910

Alternate gene names: 209548513

Gene position: 925983-926594 (Clockwise)

Preceding gene: 209548511

Following gene: 209548514

Centisome position: 20.41

GC content: 64.22

Gene sequence:

>612_bases
ATGAAACTCTACCATCACCCGCTTTCCGGCCATTCGCACCGGGTTCACCTGTTTCTGTCGCTGCTCGGCGTGCCCTATGA
GCTGGTCGAGGTCGATCTGTCGGCGCGCGCCCACAAGGCGCCGGAATTTCTGAAGCTCAACCCCTTCGGCCAGGTGCCGG
TCCTCGACGACGAGGGCACGGTCATTGCCGATTCTTCTGCCATCCTCGTCTATCTCGCGCGCAAATATGGCCGCACCGAC
TGGCTGCCGGAACAGGCATTGGCCGCGGCGCGAATACAGAAATGGCTCTCGGTTGCTGCTGGTGAGATCGCCTACGGACC
GTGCGCCGCCCGCCTGGTTACCGTTTTCGGCGCCGATTTCCGCGCCGATGAGGTGATCGCCCGGGCGCACCGCATTCTGG
CGCTGATCGAGGCGGAGCTCGCCGGCCGCAATTTCCTGCTCGGCGACAATCCCGTCATCGCCGACGTCGCGCTCTACAGC
TACATCGCCAATGCGCCGGAGGGCAATGTCGACATCTCGGCCTATCCGAGCGTCCGCGCCTGGCTTGCCCGCATCGAGGC
GCTGCCGGGTTTCGTCGGCTTTCGCAAGACGAAGATCGGCCTTGCCGCATGA

Upstream 100 bases:

>100_bases
TACTGCAATCCAATGGAAGGCAATACATTCCTCCGCAGATGGTTCGCAGGCGGCCATCGTCAATCATGGCCCGTTGATCG
GGAGACCAAAGGAAACCCTT

Downstream 100 bases:

>100_bases
GACTGCGCCGGGACGGATCACCGTCCCGGTTTCCCAAATGGTGCCCGCAAGGAGGCCGTCATGCTGGAGCAGACAAGAGA
GGACGCAACGTCACCCTGGC

Product: glutathione S-transferase domain

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKLYHHPLSGHSHRVHLFLSLLGVPYELVEVDLSARAHKAPEFLKLNPFGQVPVLDDEGTVIADSSAILVYLARKYGRTD
WLPEQALAAARIQKWLSVAAGEIAYGPCAARLVTVFGADFRADEVIARAHRILALIEAELAGRNFLLGDNPVIADVALYS
YIANAPEGNVDISAYPSVRAWLARIEALPGFVGFRKTKIGLAA

Sequences:

>Translated_203_residues
MKLYHHPLSGHSHRVHLFLSLLGVPYELVEVDLSARAHKAPEFLKLNPFGQVPVLDDEGTVIADSSAILVYLARKYGRTD
WLPEQALAAARIQKWLSVAAGEIAYGPCAARLVTVFGADFRADEVIARAHRILALIEAELAGRNFLLGDNPVIADVALYS
YIANAPEGNVDISAYPSVRAWLARIEALPGFVGFRKTKIGLAA
>Mature_203_residues
MKLYHHPLSGHSHRVHLFLSLLGVPYELVEVDLSARAHKAPEFLKLNPFGQVPVLDDEGTVIADSSAILVYLARKYGRTD
WLPEQALAAARIQKWLSVAAGEIAYGPCAARLVTVFGADFRADEVIARAHRILALIEAELAGRNFLLGDNPVIADVALYS
YIANAPEGNVDISAYPSVRAWLARIEALPGFVGFRKTKIGLAA

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI4504187, Length=200, Percent_Identity=32, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI124249394, Length=200, Percent_Identity=32, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI167466164, Length=201, Percent_Identity=29.3532338308458, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI22202624, Length=194, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788640, Length=201, Percent_Identity=26.865671641791, Blast_Score=72, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551302, Length=197, Percent_Identity=27.9187817258883, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI20130115, Length=185, Percent_Identity=35.6756756756757, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19922526, Length=192, Percent_Identity=34.375, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24654992, Length=184, Percent_Identity=36.4130434782609, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI19922532, Length=186, Percent_Identity=34.9462365591398, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24654983, Length=181, Percent_Identity=33.7016574585635, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI45549270, Length=194, Percent_Identity=28.8659793814433, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24654979, Length=181, Percent_Identity=30.939226519337, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24654975, Length=188, Percent_Identity=35.1063829787234, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221378141, Length=185, Percent_Identity=31.3513513513514, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17864594, Length=193, Percent_Identity=28.4974093264249, Blast_Score=80, Evalue=8e-16,
Organism=Drosophila melanogaster, GI62472445, Length=185, Percent_Identity=31.3513513513514, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922932, Length=198, Percent_Identity=29.2929292929293, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17864592, Length=183, Percent_Identity=29.5081967213115, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI20130123, Length=199, Percent_Identity=30.6532663316583, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24654965, Length=184, Percent_Identity=32.6086956521739, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571670, Length=173, Percent_Identity=28.9017341040462, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17933730, Length=185, Percent_Identity=25.9459459459459, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17864598, Length=193, Percent_Identity=28.4974093264249, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI85725204, Length=191, Percent_Identity=28.7958115183246, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17737923, Length=191, Percent_Identity=28.7958115183246, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646249, Length=194, Percent_Identity=26.8041237113402, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221378983, Length=185, Percent_Identity=27.027027027027, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24646259, Length=185, Percent_Identity=27.027027027027, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24654996, Length=181, Percent_Identity=29.8342541436464, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI20129811, Length=181, Percent_Identity=28.1767955801105, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19922528, Length=200, Percent_Identity=31, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 22110; Mature: 22110

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYHHPLSGHSHRVHLFLSLLGVPYELVEVDLSARAHKAPEFLKLNPFGQVPVLDDEGT
CCEECCCCCCCCHHHHHHHHHHCCCHHHEEECHHHHCCCCCCEEEECCCCCCEEECCCCC
VIADSSAILVYLARKYGRTDWLPEQALAAARIQKWLSVAAGEIAYGPCAARLVTVFGADF
EEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
RADEVIARAHRILALIEAELAGRNFLLGDNPVIADVALYSYIANAPEGNVDISAYPSVRA
CHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHH
WLARIEALPGFVGFRKTKIGLAA
HHHHHHHCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MKLYHHPLSGHSHRVHLFLSLLGVPYELVEVDLSARAHKAPEFLKLNPFGQVPVLDDEGT
CCEECCCCCCCCHHHHHHHHHHCCCHHHEEECHHHHCCCCCCEEEECCCCCCEEECCCCC
VIADSSAILVYLARKYGRTDWLPEQALAAARIQKWLSVAAGEIAYGPCAARLVTVFGADF
EEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
RADEVIARAHRILALIEAELAGRNFLLGDNPVIADVALYSYIANAPEGNVDISAYPSVRA
CHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHH
WLARIEALPGFVGFRKTKIGLAA
HHHHHHHCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA