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The map label for this gene is ptrB [H]

Identifier: 209548463

GI number: 209548463

Start: 878817

End: 880925

Strand: Reverse

Name: ptrB [H]

Synonym: Rleg2_0860

Alternate gene names: 209548463

Gene position: 880925-878817 (Counterclockwise)

Preceding gene: 209548466

Following gene: 209548462

Centisome position: 19.41

GC content: 62.4

Gene sequence:

>2109_bases
TTGTCCGTTTTCAACAGCCTGCCGACACCGCCCGCCGCACCGAAGAAGCCCGTCTCCGATACGCGCCACGGCATTACCCG
CACGGACGATTATGCCTGGCTGCGCGCCGATAACTGGCAGGCCATGTTCAAGGATCCTTCGATCCTCGACCCAGAGATCC
GCCGGCATCTCGAAGCCGAAAACACCTATATGAACGCTGCGATGGAAGACACCAAGCCGCTGCAGAAGCTGCTGTTTTCC
GAAATGCGCGGCCGCATCAAGGAAGACGACAGCTCGGTGCCGGTGAAGGACGGCGCCTATGCCTATGGCACATCCTACGT
GACCGGCGGCGAACAGCCGCGCTATTTCCGCATCGCCCGCGACGGCGACGTCGCCGACGAGACGATCCGCACGGTGCTGC
TCGACGGCGACAAGGAGGCATCGGGCAAGGCCTATTTCCGCCTCGCCGGTCTCGACCATACGACCGATCATAGCCACGGC
ATCTGGGGCTATGACGATAAGGGCTCGGAATTCTTCACGCTGAAAGTCCGCGACCTCGCGACCGGCCAGGACCTCGAAGA
CCGGATCGAGAATACCGGCGGCGGCGGCGTCTGGGCGCCGGACGGCAAGAGCTTCTTCTATTCCGCACTCGACGAGAACC
ACCGGCCCTCGAAGGTGTTCCACCATATTGTCGGCCAGCCGCAGTCGGAAGACCGGCTGGTTTATGAGGAAGCCGATGCC
GGCTTCTTCATGGGCGTCGGCGGCTCGCTGCTCGACGATGTCATCTATATCGACATTCACGATCACGAAACCAGCGAATA
CCGGCTGCTGTCGACCAAGGATCTGACGGCCGAGCCGAAGCTGGTGGCAGCGCGCGAGGAAGGCATCGAATATTCGCTGA
CCGAGGGCGGCGACATCTTCTATATCCTCACCAATGACGGCGGCGCCAAGGATTTCAAGATCATGGAAGCGCCTGTCGAC
AATCCGGGCAAGGAAAACTGGCGCGAAGTGGTCGCCCACAAGCCCGGCACGCTGATCATCAGCCACATGGCCTATGCCCG
CCACCTTCTGTGGCTGGAACGCAAGGACGGGCTGCCGCAGATCATGATCCGCGACCGCAAGACCGGCGAGGAACATGCGA
TCGCCTTTGCCGAGGAAGCCTATTCGCTGGGGCTTTCGGGTGCGGCGGAATACGACACGGATGTCATCCGCTTCTCCTAT
TCGTCGATGACGACGCCGTCGCAGCTCTACGATTACAATATGGTGACGCGCGAGCGCACACTGCTCAAGACGCAGGAGGT
GCCGTCGGGCCACAATCCCGACGATTACATCACCCGCCGCGTCTTCGCGCCGGCCTGGGACGGCGAGACGGTGCCGGTCA
CCCTGCTCTATCGCAAGGACACGCCGCTCGACGGCACCGCGCCCTGCCTGCTCTATGGCTACGGCGCCTACGGCATCACC
ATTCCGGCCGGCTTCAACACCAATTGCCTGTCGCTTGCCGATCGCGGCTTCGTCTATGCCATCGCCCACATCCGCGGCGG
CAAGGACAAGGGATTTTCCTGGTACGAAGACGGCAAGATGGACAAGAAGACGAATACCTTCAAGGACTTCGTCGCTGCTG
CCGACTATCTGAATCAACAGAAGTTCACCTCTTACGCGAAGATCATCGCCGAGGGCGGCTCGGCCGGCGGCATGCTGATG
GGCGCCGTCGCCAACATGGCGCCGGAAAAATTCGCCGGCCTCATCGCCGCCGTCCCCTTCGTCGACGTGCTCAACACCAT
GCTCGACGACACGCTGCCGCTCACCCCGCCGGAATGGCCGGAATGGGGGAACCCGATCGACAGCCAGGAAGAATACGAGC
AGATCGCCGCCTACTCGCCTTATGACAATGTCGCCGCCAAGGCCTACCCGCCGATTCTGGCGCTCGGCGGCCTGACCGAC
CCGCGCGTCACCTATTGGGAGCCGGCCAAATGGGTGGCGAAGCTGCGCGACCAGACGACCGGCGCAGCGCCGATCCTGCT
CAAGACCAATATGGACGCGGGCCATGGCGGCGCGTCCGGCCGCTTCCAGCGGCTGGAAGAGATTGCGTTCGAGTATGCGT
TTGCGATCAAGGTAGCGGGGAAGATGTGA

Upstream 100 bases:

>100_bases
TGGAAGCTTATCTACCGCCTTGGCGCAGCCTTGCCGCTTGATCCGGCGGCGACGCGCCTCTATCTCTTGCCAACCCGATA
TCCCGATCCGGAGCCATTCC

Downstream 100 bases:

>100_bases
AATCTTTGAGGGGTGTGCCGTGGTCACCCCCCTCTGCCCTGCCGGGCATCTCCCCCACGGGTGGGGAGATCGCAAGTGGC
CAGACCTTCGCGTCCGTCTA

Product: oligopeptidase B

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MSVFNSLPTPPAAPKKPVSDTRHGITRTDDYAWLRADNWQAMFKDPSILDPEIRRHLEAENTYMNAAMEDTKPLQKLLFS
EMRGRIKEDDSSVPVKDGAYAYGTSYVTGGEQPRYFRIARDGDVADETIRTVLLDGDKEASGKAYFRLAGLDHTTDHSHG
IWGYDDKGSEFFTLKVRDLATGQDLEDRIENTGGGGVWAPDGKSFFYSALDENHRPSKVFHHIVGQPQSEDRLVYEEADA
GFFMGVGGSLLDDVIYIDIHDHETSEYRLLSTKDLTAEPKLVAAREEGIEYSLTEGGDIFYILTNDGGAKDFKIMEAPVD
NPGKENWREVVAHKPGTLIISHMAYARHLLWLERKDGLPQIMIRDRKTGEEHAIAFAEEAYSLGLSGAAEYDTDVIRFSY
SSMTTPSQLYDYNMVTRERTLLKTQEVPSGHNPDDYITRRVFAPAWDGETVPVTLLYRKDTPLDGTAPCLLYGYGAYGIT
IPAGFNTNCLSLADRGFVYAIAHIRGGKDKGFSWYEDGKMDKKTNTFKDFVAAADYLNQQKFTSYAKIIAEGGSAGGMLM
GAVANMAPEKFAGLIAAVPFVDVLNTMLDDTLPLTPPEWPEWGNPIDSQEEYEQIAAYSPYDNVAAKAYPPILALGGLTD
PRVTYWEPAKWVAKLRDQTTGAAPILLKTNMDAGHGGASGRFQRLEEIAFEYAFAIKVAGKM

Sequences:

>Translated_702_residues
MSVFNSLPTPPAAPKKPVSDTRHGITRTDDYAWLRADNWQAMFKDPSILDPEIRRHLEAENTYMNAAMEDTKPLQKLLFS
EMRGRIKEDDSSVPVKDGAYAYGTSYVTGGEQPRYFRIARDGDVADETIRTVLLDGDKEASGKAYFRLAGLDHTTDHSHG
IWGYDDKGSEFFTLKVRDLATGQDLEDRIENTGGGGVWAPDGKSFFYSALDENHRPSKVFHHIVGQPQSEDRLVYEEADA
GFFMGVGGSLLDDVIYIDIHDHETSEYRLLSTKDLTAEPKLVAAREEGIEYSLTEGGDIFYILTNDGGAKDFKIMEAPVD
NPGKENWREVVAHKPGTLIISHMAYARHLLWLERKDGLPQIMIRDRKTGEEHAIAFAEEAYSLGLSGAAEYDTDVIRFSY
SSMTTPSQLYDYNMVTRERTLLKTQEVPSGHNPDDYITRRVFAPAWDGETVPVTLLYRKDTPLDGTAPCLLYGYGAYGIT
IPAGFNTNCLSLADRGFVYAIAHIRGGKDKGFSWYEDGKMDKKTNTFKDFVAAADYLNQQKFTSYAKIIAEGGSAGGMLM
GAVANMAPEKFAGLIAAVPFVDVLNTMLDDTLPLTPPEWPEWGNPIDSQEEYEQIAAYSPYDNVAAKAYPPILALGGLTD
PRVTYWEPAKWVAKLRDQTTGAAPILLKTNMDAGHGGASGRFQRLEEIAFEYAFAIKVAGKM
>Mature_701_residues
SVFNSLPTPPAAPKKPVSDTRHGITRTDDYAWLRADNWQAMFKDPSILDPEIRRHLEAENTYMNAAMEDTKPLQKLLFSE
MRGRIKEDDSSVPVKDGAYAYGTSYVTGGEQPRYFRIARDGDVADETIRTVLLDGDKEASGKAYFRLAGLDHTTDHSHGI
WGYDDKGSEFFTLKVRDLATGQDLEDRIENTGGGGVWAPDGKSFFYSALDENHRPSKVFHHIVGQPQSEDRLVYEEADAG
FFMGVGGSLLDDVIYIDIHDHETSEYRLLSTKDLTAEPKLVAAREEGIEYSLTEGGDIFYILTNDGGAKDFKIMEAPVDN
PGKENWREVVAHKPGTLIISHMAYARHLLWLERKDGLPQIMIRDRKTGEEHAIAFAEEAYSLGLSGAAEYDTDVIRFSYS
SMTTPSQLYDYNMVTRERTLLKTQEVPSGHNPDDYITRRVFAPAWDGETVPVTLLYRKDTPLDGTAPCLLYGYGAYGITI
PAGFNTNCLSLADRGFVYAIAHIRGGKDKGFSWYEDGKMDKKTNTFKDFVAAADYLNQQKFTSYAKIIAEGGSAGGMLMG
AVANMAPEKFAGLIAAVPFVDVLNTMLDDTLPLTPPEWPEWGNPIDSQEEYEQIAAYSPYDNVAAKAYPPILALGGLTDP
RVTYWEPAKWVAKLRDQTTGAAPILLKTNMDAGHGGASGRFQRLEEIAFEYAFAIKVAGKM

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI41349456, Length=730, Percent_Identity=26.3013698630137, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI284172438, Length=462, Percent_Identity=29.2207792207792, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI284172431, Length=462, Percent_Identity=29.2207792207792, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI284172420, Length=462, Percent_Identity=29.2207792207792, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI284172413, Length=462, Percent_Identity=29.2207792207792, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI70778815, Length=462, Percent_Identity=29.2207792207792, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI108860686, Length=265, Percent_Identity=34.3396226415094, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI108860692, Length=211, Percent_Identity=36.4928909952607, Blast_Score=132, Evalue=1e-30,
Organism=Escherichia coli, GI1788150, Length=690, Percent_Identity=39.1304347826087, Blast_Score=451, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24583414, Length=715, Percent_Identity=25.4545454545455, Blast_Score=200, Evalue=2e-51,
Organism=Drosophila melanogaster, GI221510989, Length=725, Percent_Identity=23.8620689655172, Blast_Score=171, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 77964; Mature: 77833

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFNSLPTPPAAPKKPVSDTRHGITRTDDYAWLRADNWQAMFKDPSILDPEIRRHLEAE
CCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHH
NTYMNAAMEDTKPLQKLLFSEMRGRIKEDDSSVPVKDGAYAYGTSYVTGGEQPRYFRIAR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEECCCCCCCEEEEEC
DGDVADETIRTVLLDGDKEASGKAYFRLAGLDHTTDHSHGIWGYDDKGSEFFTLKVRDLA
CCCCHHHHEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECC
TGQDLEDRIENTGGGGVWAPDGKSFFYSALDENHRPSKVFHHIVGQPQSEDRLVYEEADA
CCCCHHHHHHCCCCCCEECCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCC
GFFMGVGGSLLDDVIYIDIHDHETSEYRLLSTKDLTAEPKLVAAREEGIEYSLTEGGDIF
CEEEECCHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCCEEEEHHCCCEEEECCCCEEE
YILTNDGGAKDFKIMEAPVDNPGKENWREVVAHKPGTLIISHMAYARHLLWLERKDGLPQ
EEEECCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHEEECCCCCCE
IMIRDRKTGEEHAIAFAEEAYSLGLSGAAEYDTDVIRFSYSSMTTPSQLYDYNMVTRERT
EEEECCCCCCHHHHEEHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHCCHHHHHHHH
LLKTQEVPSGHNPDDYITRRVFAPAWDGETVPVTLLYRKDTPLDGTAPCLLYGYGAYGIT
HHHHHCCCCCCCCHHHHHHHEECCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCEEE
IPAGFNTNCLSLADRGFVYAIAHIRGGKDKGFSWYEDGKMDKKTNTFKDFVAAADYLNQQ
ECCCCCCCHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KFTSYAKIIAEGGSAGGMLMGAVANMAPEKFAGLIAAVPFVDVLNTMLDDTLPLTPPEWP
HHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EWGNPIDSQEEYEQIAAYSPYDNVAAKAYPPILALGGLTDPRVTYWEPAKWVAKLRDQTT
CCCCCCCCHHHHHHHHCCCCCCCCCHHHCCCEEEECCCCCCCEEEECHHHHHHHHHHCCC
GAAPILLKTNMDAGHGGASGRFQRLEEIAFEYAFAIKVAGKM
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCC
>Mature Secondary Structure 
SVFNSLPTPPAAPKKPVSDTRHGITRTDDYAWLRADNWQAMFKDPSILDPEIRRHLEAE
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEECCCCEEECCCCCCCHHHHHHHHHH
NTYMNAAMEDTKPLQKLLFSEMRGRIKEDDSSVPVKDGAYAYGTSYVTGGEQPRYFRIAR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEECCCCCCCEEEEEC
DGDVADETIRTVLLDGDKEASGKAYFRLAGLDHTTDHSHGIWGYDDKGSEFFTLKVRDLA
CCCCHHHHEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECC
TGQDLEDRIENTGGGGVWAPDGKSFFYSALDENHRPSKVFHHIVGQPQSEDRLVYEEADA
CCCCHHHHHHCCCCCCEECCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEEECCC
GFFMGVGGSLLDDVIYIDIHDHETSEYRLLSTKDLTAEPKLVAAREEGIEYSLTEGGDIF
CEEEECCHHHHCCEEEEEEECCCCCCEEEEECCCCCCCCCEEEEHHCCCEEEECCCCEEE
YILTNDGGAKDFKIMEAPVDNPGKENWREVVAHKPGTLIISHMAYARHLLWLERKDGLPQ
EEEECCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHEEECCCCCCE
IMIRDRKTGEEHAIAFAEEAYSLGLSGAAEYDTDVIRFSYSSMTTPSQLYDYNMVTRERT
EEEECCCCCCHHHHEEHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHCCHHHHHHHH
LLKTQEVPSGHNPDDYITRRVFAPAWDGETVPVTLLYRKDTPLDGTAPCLLYGYGAYGIT
HHHHHCCCCCCCCHHHHHHHEECCCCCCCCEEEEEEEECCCCCCCCCCEEEEECCCCEEE
IPAGFNTNCLSLADRGFVYAIAHIRGGKDKGFSWYEDGKMDKKTNTFKDFVAAADYLNQQ
ECCCCCCCHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
KFTSYAKIIAEGGSAGGMLMGAVANMAPEKFAGLIAAVPFVDVLNTMLDDTLPLTPPEWP
HHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EWGNPIDSQEEYEQIAAYSPYDNVAAKAYPPILALGGLTDPRVTYWEPAKWVAKLRDQTT
CCCCCCCCHHHHHHHHCCCCCCCCCHHHCCCEEEECCCCCCCEEEECHHHHHHHHHHCCC
GAAPILLKTNMDAGHGGASGRFQRLEEIAFEYAFAIKVAGKM
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]