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The map label for this gene is yfhR [C]

Identifier: 209548325

GI number: 209548325

Start: 743526

End: 744338

Strand: Reverse

Name: yfhR [C]

Synonym: Rleg2_0720

Alternate gene names: 209548325

Gene position: 744338-743526 (Counterclockwise)

Preceding gene: 209548328

Following gene: 209548323

Centisome position: 16.4

GC content: 60.27

Gene sequence:

>813_bases
GTGAGCGCTACAAAATACTTGCTGATCTTGCCGCTGATGGCGGTTATTGCCTACGTGGCGTTCGTGGGTCTGATCTATCT
GTCTCAGCGAGCCCTGCTCTTTCCCGGAGCCGGCGCCACACCTGTTCCGGAGCAGGCGAGTTGGGGCGAGACGGTCCGCA
TCAAGACGCCCGACGGGGAGATGCTTTATGGACTGTACAGCCAGGGCGACAGCGACAAGCCCTGCGTGCTCCTCTTTTTC
GGAAACGGTGATCGCGTCGACAATTACGCGTTTCTCGCACAGGCGCTGGCCACGCGGAGGATTGGATTGCTGGCGATTTC
CTATCGCGGCTATCCCGGATCGACCGGCGCCCCCAGCGAGCAGGGGCTGCTGACAGACGGCATCGCCGCGTTCGACTGGC
TTTCGGCACATGCCGGAAGCGGGATCGTTGTGCTGGGCCGGTCACTTGGCACCGGCGTTGCTGTGAATACCGCAGCGAAG
AGGCCGGCCGTGGGCGTCATTCTTGTGTCTCCGTACCTGTCGGTTCTGTCGGTCGCGCAGACGCATTATCCGTTCCTCCC
GGTCGAGCTTCTTCTCAAGGATCCCTTTCGCTCGGACCTCAACATCGGCAAAGTAGGACAACCGAAGTTGTTCCTCCACG
GCCGGCTTGATGACAGCATCCCGCTTTCGTCAGGGCAGGCGTTGTACAGCCTCGCACCCGAGCCCAAGCAGATGTTGATC
TATGACGGTGCGGGTCACAACGATATCTTGAACGATCGCATGGTCGGTGACGTGATCCGTTTTGTGGAAGCGCTGAAAGG
AAACGGGGCCTAG

Upstream 100 bases:

>100_bases
TCACCCCCAACGCCTGGGACGCTGAGCACACCCCGCCGCCGCGGGCCGCGGCTGCCGCAAAGCGTTCTGGGCATTGCCAA
ACCGGCGGGTACAGTCTGTC

Downstream 100 bases:

>100_bases
GGCGCCCTCTTCGTCCTGAGCGCGCCTTCCTCAGCATGGGTCCTCGGGTCAAGCCCGAGGACGACGGAGGCTGGGGTGGG
CTCGTGGCAAACCCTACGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSATKYLLILPLMAVIAYVAFVGLIYLSQRALLFPGAGATPVPEQASWGETVRIKTPDGEMLYGLYSQGDSDKPCVLLFF
GNGDRVDNYAFLAQALATRRIGLLAISYRGYPGSTGAPSEQGLLTDGIAAFDWLSAHAGSGIVVLGRSLGTGVAVNTAAK
RPAVGVILVSPYLSVLSVAQTHYPFLPVELLLKDPFRSDLNIGKVGQPKLFLHGRLDDSIPLSSGQALYSLAPEPKQMLI
YDGAGHNDILNDRMVGDVIRFVEALKGNGA

Sequences:

>Translated_270_residues
MSATKYLLILPLMAVIAYVAFVGLIYLSQRALLFPGAGATPVPEQASWGETVRIKTPDGEMLYGLYSQGDSDKPCVLLFF
GNGDRVDNYAFLAQALATRRIGLLAISYRGYPGSTGAPSEQGLLTDGIAAFDWLSAHAGSGIVVLGRSLGTGVAVNTAAK
RPAVGVILVSPYLSVLSVAQTHYPFLPVELLLKDPFRSDLNIGKVGQPKLFLHGRLDDSIPLSSGQALYSLAPEPKQMLI
YDGAGHNDILNDRMVGDVIRFVEALKGNGA
>Mature_269_residues
SATKYLLILPLMAVIAYVAFVGLIYLSQRALLFPGAGATPVPEQASWGETVRIKTPDGEMLYGLYSQGDSDKPCVLLFFG
NGDRVDNYAFLAQALATRRIGLLAISYRGYPGSTGAPSEQGLLTDGIAAFDWLSAHAGSGIVVLGRSLGTGVAVNTAAKR
PAVGVILVSPYLSVLSVAQTHYPFLPVELLLKDPFRSDLNIGKVGQPKLFLHGRLDDSIPLSSGQALYSLAPEPKQMLIY
DGAGHNDILNDRMVGDVIRFVEALKGNGA

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI32451492, Length=183, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32528310, Length=183, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI109689718, Length=183, Percent_Identity=32.2404371584699, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI24308097, Length=183, Percent_Identity=32.2404371584699, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI151301175, Length=235, Percent_Identity=31.4893617021277, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI71051602, Length=226, Percent_Identity=30.0884955752212, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI71051600, Length=226, Percent_Identity=30.0884955752212, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI194306564, Length=196, Percent_Identity=31.6326530612245, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194306562, Length=192, Percent_Identity=31.7708333333333, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355781, Length=250, Percent_Identity=30.8, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI226510965, Length=224, Percent_Identity=29.0178571428571, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71988362, Length=178, Percent_Identity=32.5842696629214, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17566318, Length=187, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17532877, Length=183, Percent_Identity=32.7868852459016, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71985387, Length=186, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71985392, Length=189, Percent_Identity=29.6296296296296, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=256, Percent_Identity=28.90625, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17137566, Length=239, Percent_Identity=30.9623430962343, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281362521, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI281362519, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571878, Length=223, Percent_Identity=28.2511210762332, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24655464, Length=172, Percent_Identity=30.2325581395349, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24655467, Length=172, Percent_Identity=30.2325581395349, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 28723; Mature: 28591

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATKYLLILPLMAVIAYVAFVGLIYLSQRALLFPGAGATPVPEQASWGETVRIKTPDGE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEEEECCCCC
MLYGLYSQGDSDKPCVLLFFGNGDRVDNYAFLAQALATRRIGLLAISYRGYPGSTGAPSE
EEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCC
QGLLTDGIAAFDWLSAHAGSGIVVLGRSLGTGVAVNTAAKRPAVGVILVSPYLSVLSVAQ
CCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHH
THYPFLPVELLLKDPFRSDLNIGKVGQPKLFLHGRLDDSIPLSSGQALYSLAPEPKQMLI
HCCCCCHHHHEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCEEEE
YDGAGHNDILNDRMVGDVIRFVEALKGNGA
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SATKYLLILPLMAVIAYVAFVGLIYLSQRALLFPGAGATPVPEQASWGETVRIKTPDGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCEEEEECCCCC
MLYGLYSQGDSDKPCVLLFFGNGDRVDNYAFLAQALATRRIGLLAISYRGYPGSTGAPSE
EEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCCCC
QGLLTDGIAAFDWLSAHAGSGIVVLGRSLGTGVAVNTAAKRPAVGVILVSPYLSVLSVAQ
CCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHH
THYPFLPVELLLKDPFRSDLNIGKVGQPKLFLHGRLDDSIPLSSGQALYSLAPEPKQMLI
HCCCCCHHHHEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCEEEE
YDGAGHNDILNDRMVGDVIRFVEALKGNGA
ECCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]