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The map label for this gene is mcpA [H]

Identifier: 209548246

GI number: 209548246

Start: 664878

End: 666692

Strand: Reverse

Name: mcpA [H]

Synonym: Rleg2_0640

Alternate gene names: 209548246

Gene position: 666692-664878 (Counterclockwise)

Preceding gene: 209548247

Following gene: 209548245

Centisome position: 14.69

GC content: 62.81

Gene sequence:

>1815_bases
ATGGCGTCGATCCAGCATAAGATCATCATTGCAAGCATCGCGATTTTCGCCTTGGCGGGCGGCGCCACGGGGGTCGGCAT
CTGGTCTGCCTCCACGCTTTCGGCCAACAGCGCCGATGTCGCCCAGTCGGCGCAAATTCTGCGCAACCACATGCAGGCCG
ATATGATGCATGACGCGTTGCGCGCCGACGTGCTCGCCTCCCTGCTGGCATCCAACCCGGCGGCAGGCATAGACGCCGCC
GCGGTGAAAGCGGATCTGGCGGAGCACGAGGCATCGTTCCGCGAGATGATCGACGCCAATAAGGCGCTTGTCTCCGACGC
AAAAACGAAAGCGGTTCTTGCCGACATCGAACAGCCCCTTCTCGTCTATGTCGACAGCGCCACGAAGATGGTCGATCTCG
CGGGCAAGGATTCGGCGGCGGCGTTGAAGGCGCTGCCGGAATTCATGGGGCAGTTCTCGACATTGGAAACGGCCATGGAA
CAGGCCGGGGATCAGATCACCGCCGTATCGGATGATATTTCCAAGCGTAGCGCCGACATCAAAGCCTCGGTCGATATCAC
TCTCAAAGCCCTTCTGGCCTCGGCCGCGTTGTTCGCCTTCGGTCTTTATTTCCTGACCCGCAAAACCGTCACCAAGCCGA
TCCTTTCGCTTTCCAACGATATGCAAAGGCTCGCCGGCGGTGACACCGCCATTGCCTGCACCGGGATCGGCCGCGCTGAC
GAAATCGGCACGATGGCATCGGCTGTCGAAATCTTCCGCCAGGCAGCGATTGCCAATAAGCAGCTCGAGCAGGATGCCGA
GACCGCTCGCCTGCAGGGCGAAACCGAGCGGGTCACGGCCCGCAAGCAGGCGGACGAGGATGCGGCCGAACGGCTGCGGG
CAGCGACATCCGGTCTCGCCGCAGGCCTGAAGCGGCTTGCCTCCGGCGATCTCGCCTTCCAGATCGAAGAACCCTTTGCC
CCCGATTTCGAGAGCCTCCGGCATGATTTCAACATGTCGATCCGCCAGCTCGATCAGACACTCGGCGCTATCGCCACGGC
CATTGCCGCGATCGACGAAGGCACAAGGGAAATTGCCTCCGGGGCCGGCGACCTGTCGAAACGCACCGAACAGCAGGCGG
CCTCGCTCGAACAAACCGCCGCAGCGCTCGATCAGATCACCGCCAATGTGTCGAACTCCAGCAAGCGCACCGACGAGGCG
CGCACCGAGGCGACGGACGCCAATCGCAATGCCGCCAAATCGGCGGAGGTCGTGTCGCATGCCGAAGAGGCCATGCGCCG
CATCGAGGCCTCGTCGCAGCAGATCTCCAGCATCATTGGCGTAATCGACGAAATCGCCTTCCAGACCAACCTGCTGGCCC
TAAACGCCGGCGTCGAAGCTGCCCGCGCCGGCGAAGCCGGCAAGGGCTTTGCCGTCGTTGCCCAGGAAGTCCGCGAACTC
GCCCAGCGCTCGGCGCAGGCGGCAAAGGAAATCAAGGGCCACATCCAGAAATCGTCGGTGGAAGTGGAAAGCGGCGTCAA
GCTGGTTCTCGACACCAGCCAGGTTCTGAGCGCGATCAGCGAGCAGATCGCCCGCATCAACCAGCACATGGATGCCATCG
CCGTATCGGCCCGCGAGCAGTCGACCGGTCTTGCCGAAGTCAATACCGCCGTCAATTCGATGGATCACGTGACCCAGCAG
AATGCGGCGATGGTCGAGCAGTCGACCGCCGCATCCGGCCATCTGGCTCAGGAAGCCGCCAAGCTGCGCGAACTCGTGTC
CCGCTTCAAGCTGCGTGCGACGGCTTCGACACAATTCGCACGACGGGCGGCGTGA

Upstream 100 bases:

>100_bases
TACAACCTGTTGTTTTTACGCGGCTTAGCGCGGTCTCGCTGAGAAATCATTAAGCATGTTCCGATAATCTCAGGTTCTAC
ATTAACGTGAGAGCCCCGAC

Downstream 100 bases:

>100_bases
CGGCTTCTCTCCGCTCACCATTGTTCACGCCTGCGATTTCGGCGGTCTGAAATGATCGCCGTTCGCCGCTCGATCCCCTC
CTCCCCAGCGGTCGCCAAAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 604; Mature: 603

Protein sequence:

>604_residues
MASIQHKIIIASIAIFALAGGATGVGIWSASTLSANSADVAQSAQILRNHMQADMMHDALRADVLASLLASNPAAGIDAA
AVKADLAEHEASFREMIDANKALVSDAKTKAVLADIEQPLLVYVDSATKMVDLAGKDSAAALKALPEFMGQFSTLETAME
QAGDQITAVSDDISKRSADIKASVDITLKALLASAALFAFGLYFLTRKTVTKPILSLSNDMQRLAGGDTAIACTGIGRAD
EIGTMASAVEIFRQAAIANKQLEQDAETARLQGETERVTARKQADEDAAERLRAATSGLAAGLKRLASGDLAFQIEEPFA
PDFESLRHDFNMSIRQLDQTLGAIATAIAAIDEGTREIASGAGDLSKRTEQQAASLEQTAAALDQITANVSNSSKRTDEA
RTEATDANRNAAKSAEVVSHAEEAMRRIEASSQQISSIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
AQRSAQAAKEIKGHIQKSSVEVESGVKLVLDTSQVLSAISEQIARINQHMDAIAVSAREQSTGLAEVNTAVNSMDHVTQQ
NAAMVEQSTAASGHLAQEAAKLRELVSRFKLRATASTQFARRAA

Sequences:

>Translated_604_residues
MASIQHKIIIASIAIFALAGGATGVGIWSASTLSANSADVAQSAQILRNHMQADMMHDALRADVLASLLASNPAAGIDAA
AVKADLAEHEASFREMIDANKALVSDAKTKAVLADIEQPLLVYVDSATKMVDLAGKDSAAALKALPEFMGQFSTLETAME
QAGDQITAVSDDISKRSADIKASVDITLKALLASAALFAFGLYFLTRKTVTKPILSLSNDMQRLAGGDTAIACTGIGRAD
EIGTMASAVEIFRQAAIANKQLEQDAETARLQGETERVTARKQADEDAAERLRAATSGLAAGLKRLASGDLAFQIEEPFA
PDFESLRHDFNMSIRQLDQTLGAIATAIAAIDEGTREIASGAGDLSKRTEQQAASLEQTAAALDQITANVSNSSKRTDEA
RTEATDANRNAAKSAEVVSHAEEAMRRIEASSQQISSIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
AQRSAQAAKEIKGHIQKSSVEVESGVKLVLDTSQVLSAISEQIARINQHMDAIAVSAREQSTGLAEVNTAVNSMDHVTQQ
NAAMVEQSTAASGHLAQEAAKLRELVSRFKLRATASTQFARRAA
>Mature_603_residues
ASIQHKIIIASIAIFALAGGATGVGIWSASTLSANSADVAQSAQILRNHMQADMMHDALRADVLASLLASNPAAGIDAAA
VKADLAEHEASFREMIDANKALVSDAKTKAVLADIEQPLLVYVDSATKMVDLAGKDSAAALKALPEFMGQFSTLETAMEQ
AGDQITAVSDDISKRSADIKASVDITLKALLASAALFAFGLYFLTRKTVTKPILSLSNDMQRLAGGDTAIACTGIGRADE
IGTMASAVEIFRQAAIANKQLEQDAETARLQGETERVTARKQADEDAAERLRAATSGLAAGLKRLASGDLAFQIEEPFAP
DFESLRHDFNMSIRQLDQTLGAIATAIAAIDEGTREIASGAGDLSKRTEQQAASLEQTAAALDQITANVSNSSKRTDEAR
TEATDANRNAAKSAEVVSHAEEAMRRIEASSQQISSIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELA
QRSAQAAKEIKGHIQKSSVEVESGVKLVLDTSQVLSAISEQIARINQHMDAIAVSAREQSTGLAEVNTAVNSMDHVTQQN
AAMVEQSTAASGHLAQEAAKLRELVSRFKLRATASTQFARRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=289, Percent_Identity=43.598615916955, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI2367378, Length=305, Percent_Identity=46.2295081967213, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1788194, Length=242, Percent_Identity=51.2396694214876, Blast_Score=198, Evalue=9e-52,
Organism=Escherichia coli, GI1788195, Length=303, Percent_Identity=44.2244224422442, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1789453, Length=244, Percent_Identity=36.8852459016393, Blast_Score=149, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63536; Mature: 63405

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIQHKIIIASIAIFALAGGATGVGIWSASTLSANSADVAQSAQILRNHMQADMMHDAL
CCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RADVLASLLASNPAAGIDAAAVKADLAEHEASFREMIDANKALVSDAKTKAVLADIEQPL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LVYVDSATKMVDLAGKDSAAALKALPEFMGQFSTLETAMEQAGDQITAVSDDISKRSADI
EEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCC
KASVDITLKALLASAALFAFGLYFLTRKTVTKPILSLSNDMQRLAGGDTAIACTGIGRAD
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
EIGTMASAVEIFRQAAIANKQLEQDAETARLQGETERVTARKQADEDAAERLRAATSGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
AGLKRLASGDLAFQIEEPFAPDFESLRHDFNMSIRQLDQTLGAIATAIAAIDEGTREIAS
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAGDLSKRTEQQAASLEQTAAALDQITANVSNSSKRTDEARTEATDANRNAAKSAEVVSH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
AEEAMRRIEASSQQISSIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSAQAAKEIKGHIQKSSVEVESGVKLVLDTSQVLSAISEQIARINQHMDAIAVSAREQ
HHHHHHHHHHHHHHHHHHCEEHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STGLAEVNTAVNSMDHVTQQNAAMVEQSTAASGHLAQEAAKLRELVSRFKLRATASTQFA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAA
HHCC
>Mature Secondary Structure 
ASIQHKIIIASIAIFALAGGATGVGIWSASTLSANSADVAQSAQILRNHMQADMMHDAL
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RADVLASLLASNPAAGIDAAAVKADLAEHEASFREMIDANKALVSDAKTKAVLADIEQPL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LVYVDSATKMVDLAGKDSAAALKALPEFMGQFSTLETAMEQAGDQITAVSDDISKRSADI
EEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCC
KASVDITLKALLASAALFAFGLYFLTRKTVTKPILSLSNDMQRLAGGDTAIACTGIGRAD
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHH
EIGTMASAVEIFRQAAIANKQLEQDAETARLQGETERVTARKQADEDAAERLRAATSGLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
AGLKRLASGDLAFQIEEPFAPDFESLRHDFNMSIRQLDQTLGAIATAIAAIDEGTREIAS
HHHHHHHCCCEEEEECCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GAGDLSKRTEQQAASLEQTAAALDQITANVSNSSKRTDEARTEATDANRNAAKSAEVVSH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHH
AEEAMRRIEASSQQISSIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHH
AQRSAQAAKEIKGHIQKSSVEVESGVKLVLDTSQVLSAISEQIARINQHMDAIAVSAREQ
HHHHHHHHHHHHHHHHHHCEEHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STGLAEVNTAVNSMDHVTQQNAAMVEQSTAASGHLAQEAAKLRELVSRFKLRATASTQFA
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRAA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]