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The map label for this gene is mcpA [H]

Identifier: 209548232

GI number: 209548232

Start: 647123

End: 649303

Strand: Reverse

Name: mcpA [H]

Synonym: Rleg2_0626

Alternate gene names: 209548232

Gene position: 649303-647123 (Counterclockwise)

Preceding gene: 209548233

Following gene: 209548231

Centisome position: 14.31

GC content: 63.27

Gene sequence:

>2181_bases
ATGATCAGAACCGTTTCAGCGAAACTCATCCTGGCGACCGGCACTGCGATCGCCGGCGTCCTGATCGCTTACACCGCCTT
CAATGCGGTGAGTGCCAAGAACAATACCGAGCGGGAGGTCATGGCGCTGGCGACGGAACAGGCCGCCGTGGTCAGCCAGC
AGGTGGCGACCGATATCACCGAGGCCACCTCGGCCGGCGCGGCTCTGGCCGCGAGCCTCTCGGGTTTCGTCGAGGGCGGA
TCGAAAAGCCGGGCCGACATCGTCGCGATGATCAAGACCGTGGCGCCGCAATATCCGAGCGTTTTCGGCGCCTGGATGTG
TGAGTTGATCGATGGTCCCCACCCGACGACCGGCACGGACGCCTTGAACAAGGAAGGCATTTTCACGCCCTATTGGACGA
AGGGCGACGACGGCAAGATGGAATTCTCGACGTGGAGCATCAAGCCTGAGGACGAATATTACAGCGCGCCGCTGAAGAGC
GGAAAGGCGATCATCACCTCTCCCTATCTCACCAATATGAAAAAGCTGGTCACCTCGGTGTCGGTGCCGATGCGGGTGAA
CGGGACTGTCGTCGGCCTGGCCGGCGTCGATATTAAACTCGACGATCTCACAGCTGCCCTGACCGAGATGCACCCCTTCG
ATGGCGGGCGGGTCATGCTGCTTGCCAATGACGGCAAGTGGCTCGCCCATCCCGACAAAGACAATCTGATGAAGGACTAT
GCCGACGCTGGTGCTGCCGACGTCAAGCAGGCGCTCGCCGACGGCAAGATGCGGGTAATTTCAGGATTGCCTGATGGTGC
CGTGCGCCTCGTCTATCCGTTTACTGCCCGCGGCATGAACACCACCTGGGCTGCGGTTCTCGATGTGCCGGCCGCGACCT
TCTCGGCGCCGGTCTGGCAGCAGATCTACAACACCGTCATCGGCGGCGTTCTTATTCTGGCGGTGATGCTCGGCGTCATC
CTGACGGCGAGCCGCATCCTGATCGGCAAGCCGCTGAACGGCATTCTGAGCGCCGTCCAGAAAATGGCAGGCGGGAATTA
TCGCGAGCCGATCGACCATAATGGCAGCGGCGACGAACTCGGCAGCCTGAAGGGCGCGCTCGAAAAATTTCGCCATCAGC
TCGCTCGCGGCGAGACACTCAAGGACGAGCAGGAAGCGCTGCAGGCACAGGTCGAGACCGACCGCAAACGCCAGGGCGAC
CTCGAGCAGGCCAAGGCGGAGGATCTGCGCCATTTCGTCGAAGTCGTGCAGAGCCGGTTCGACCTTCTGGCTTCGGGCGA
TCTCACCGTGCGCATGAACGAGACGGTGGCGCCTGAGTTCGAGACGATCCGGGCAAACTTCAACACGTCGGTTTCCGCCT
TGGAAGACACCATCCGCAACGTCGTCAACGCCGTATATACCATCCGCTCCGGCCTCGGCGAGATTTCGACGGCGTCGAAC
GATCTGGCGCGGCGCACGGAACAGCAGGCCGCCTCGCTGGAGGAAACCGTCGCAGCCTTGGGTGATGTCACCCGCGGCGT
CAACGACACCTCGGACGGGGCAAACAGCGCGCAGCAGACGATGAAGCTCGCCCGCGCCGACGCCGAAAAGGGCGGAGAGG
TCGTAGCCCGCGCGATCGAGGCGATGACCGAAATCCAGGGTTCCTCCGGCAAGATCGGCAATATCATCCGGGTGATCGAC
GAAATCGCCTTCCAGACGAACCTGCTTGCGCTCAATGCCGGTGTCGAGGCCGCGCGCGCCGGTGAAGCCGGCAAGGGCTT
TGCCGTCGTCGCCCAGGAAGTGCGCGAGCTCGCGCAACGCTCCGCCCAGGCGGCGAAGGAAATCAGCGGGCTGATCTCGA
TGTCGTCGTCGCAGGTTCAGACCGGCGTCAACCTGGTCGAGGAAACCGGTGTGGCGCTCTCCAAGATCGTCGATCGCGTC
GTCGGCATGAGCGACACGGTCAATGAAATCGCCACAAGTGCAAAGGCGCAGGCAACCAGCCTGCGGGAAGTGTCCGCCGC
CGCCGATCTGATGGACAAGGTCACCCAGCAGAACGCCGCGATGGTCGAGGAGACGACAGCCGCAGCACAGGGGCTTGCCC
AGGAAACGGAGAACCTCGCAGCGGTCGTCGGCCGTTTCGGCCTCGGCGGCGCCATGTCCCGCGGCAGCCAGGCGCCGGCA
GCCATGAAGCTGGCGAGCTGA

Upstream 100 bases:

>100_bases
CACGCCTGCGTGGCTCGCAATCCTCATTCAGCGCCGCCAGTCTTTCTTGATGACCTCGCGCCCACAGCACATTTCATCAG
CCGACATGAAGGGCTTTCAG

Downstream 100 bases:

>100_bases
TCCCGACCTTCACGCCGCAACGTCTGCGTGAAAATAAATACCATTGCCCTCCCGGCTTTCGCGGCTATTCTGCCGGCACA
GAAAATCGGGAGGACCACTG

Product: methyl-accepting chemotaxis sensory transducer with Cache sensor

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 726; Mature: 726

Protein sequence:

>726_residues
MIRTVSAKLILATGTAIAGVLIAYTAFNAVSAKNNTEREVMALATEQAAVVSQQVATDITEATSAGAALAASLSGFVEGG
SKSRADIVAMIKTVAPQYPSVFGAWMCELIDGPHPTTGTDALNKEGIFTPYWTKGDDGKMEFSTWSIKPEDEYYSAPLKS
GKAIITSPYLTNMKKLVTSVSVPMRVNGTVVGLAGVDIKLDDLTAALTEMHPFDGGRVMLLANDGKWLAHPDKDNLMKDY
ADAGAADVKQALADGKMRVISGLPDGAVRLVYPFTARGMNTTWAAVLDVPAATFSAPVWQQIYNTVIGGVLILAVMLGVI
LTASRILIGKPLNGILSAVQKMAGGNYREPIDHNGSGDELGSLKGALEKFRHQLARGETLKDEQEALQAQVETDRKRQGD
LEQAKAEDLRHFVEVVQSRFDLLASGDLTVRMNETVAPEFETIRANFNTSVSALEDTIRNVVNAVYTIRSGLGEISTASN
DLARRTEQQAASLEETVAALGDVTRGVNDTSDGANSAQQTMKLARADAEKGGEVVARAIEAMTEIQGSSGKIGNIIRVID
EIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAQAAKEISGLISMSSSQVQTGVNLVEETGVALSKIVDRV
VGMSDTVNEIATSAKAQATSLREVSAAADLMDKVTQQNAAMVEETTAAAQGLAQETENLAAVVGRFGLGGAMSRGSQAPA
AMKLAS

Sequences:

>Translated_726_residues
MIRTVSAKLILATGTAIAGVLIAYTAFNAVSAKNNTEREVMALATEQAAVVSQQVATDITEATSAGAALAASLSGFVEGG
SKSRADIVAMIKTVAPQYPSVFGAWMCELIDGPHPTTGTDALNKEGIFTPYWTKGDDGKMEFSTWSIKPEDEYYSAPLKS
GKAIITSPYLTNMKKLVTSVSVPMRVNGTVVGLAGVDIKLDDLTAALTEMHPFDGGRVMLLANDGKWLAHPDKDNLMKDY
ADAGAADVKQALADGKMRVISGLPDGAVRLVYPFTARGMNTTWAAVLDVPAATFSAPVWQQIYNTVIGGVLILAVMLGVI
LTASRILIGKPLNGILSAVQKMAGGNYREPIDHNGSGDELGSLKGALEKFRHQLARGETLKDEQEALQAQVETDRKRQGD
LEQAKAEDLRHFVEVVQSRFDLLASGDLTVRMNETVAPEFETIRANFNTSVSALEDTIRNVVNAVYTIRSGLGEISTASN
DLARRTEQQAASLEETVAALGDVTRGVNDTSDGANSAQQTMKLARADAEKGGEVVARAIEAMTEIQGSSGKIGNIIRVID
EIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAQAAKEISGLISMSSSQVQTGVNLVEETGVALSKIVDRV
VGMSDTVNEIATSAKAQATSLREVSAAADLMDKVTQQNAAMVEETTAAAQGLAQETENLAAVVGRFGLGGAMSRGSQAPA
AMKLAS
>Mature_726_residues
MIRTVSAKLILATGTAIAGVLIAYTAFNAVSAKNNTEREVMALATEQAAVVSQQVATDITEATSAGAALAASLSGFVEGG
SKSRADIVAMIKTVAPQYPSVFGAWMCELIDGPHPTTGTDALNKEGIFTPYWTKGDDGKMEFSTWSIKPEDEYYSAPLKS
GKAIITSPYLTNMKKLVTSVSVPMRVNGTVVGLAGVDIKLDDLTAALTEMHPFDGGRVMLLANDGKWLAHPDKDNLMKDY
ADAGAADVKQALADGKMRVISGLPDGAVRLVYPFTARGMNTTWAAVLDVPAATFSAPVWQQIYNTVIGGVLILAVMLGVI
LTASRILIGKPLNGILSAVQKMAGGNYREPIDHNGSGDELGSLKGALEKFRHQLARGETLKDEQEALQAQVETDRKRQGD
LEQAKAEDLRHFVEVVQSRFDLLASGDLTVRMNETVAPEFETIRANFNTSVSALEDTIRNVVNAVYTIRSGLGEISTASN
DLARRTEQQAASLEETVAALGDVTRGVNDTSDGANSAQQTMKLARADAEKGGEVVARAIEAMTEIQGSSGKIGNIIRVID
EIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAQAAKEISGLISMSSSQVQTGVNLVEETGVALSKIVDRV
VGMSDTVNEIATSAKAQATSLREVSAAADLMDKVTQQNAAMVEETTAAAQGLAQETENLAAVVGRFGLGGAMSRGSQAPA
AMKLAS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=294, Percent_Identity=44.8979591836735, Blast_Score=211, Evalue=2e-55,
Organism=Escherichia coli, GI1788195, Length=269, Percent_Identity=46.8401486988848, Blast_Score=196, Evalue=5e-51,
Organism=Escherichia coli, GI1787690, Length=310, Percent_Identity=43.2258064516129, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI2367378, Length=221, Percent_Identity=51.131221719457, Blast_Score=192, Evalue=8e-50,
Organism=Escherichia coli, GI1789453, Length=228, Percent_Identity=39.9122807017544, Blast_Score=152, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 76440; Mature: 76440

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTVSAKLILATGTAIAGVLIAYTAFNAVSAKNNTEREVMALATEQAAVVSQQVATDIT
CCEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EATSAGAALAASLSGFVEGGSKSRADIVAMIKTVAPQYPSVFGAWMCELIDGPHPTTGTD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
ALNKEGIFTPYWTKGDDGKMEFSTWSIKPEDEYYSAPLKSGKAIITSPYLTNMKKLVTSV
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCEEEECHHHHHHHHHHHHH
SVPMRVNGTVVGLAGVDIKLDDLTAALTEMHPFDGGRVMLLANDGKWLAHPDKDNLMKDY
CCCEEECCEEEEEECCEEEHHHHHHHHHHCCCCCCCEEEEEECCCCEECCCCHHHHHHHH
ADAGAADVKQALADGKMRVISGLPDGAVRLVYPFTARGMNTTWAAVLDVPAATFSAPVWQ
HCCCHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHCCHHHH
QIYNTVIGGVLILAVMLGVILTASRILIGKPLNGILSAVQKMAGGNYREPIDHNGSGDEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
GSLKGALEKFRHQLARGETLKDEQEALQAQVETDRKRQGDLEQAKAEDLRHFVEVVQSRF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DLLASGDLTVRMNETVAPEFETIRANFNTSVSALEDTIRNVVNAVYTIRSGLGEISTASN
HHHCCCCEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHH
DLARRTEQQAASLEETVAALGDVTRGVNDTSDGANSAQQTMKLARADAEKGGEVVARAIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
AMTEIQGSSGKIGNIIRVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQR
HHHHHCCCCCCHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
SAQAAKEISGLISMSSSQVQTGVNLVEETGVALSKIVDRVVGMSDTVNEIATSAKAQATS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LREVSAAADLMDKVTQQNAAMVEETTAAAQGLAQETENLAAVVGRFGLGGAMSRGSQAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCC
AMKLAS
HHCCCC
>Mature Secondary Structure
MIRTVSAKLILATGTAIAGVLIAYTAFNAVSAKNNTEREVMALATEQAAVVSQQVATDIT
CCEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EATSAGAALAASLSGFVEGGSKSRADIVAMIKTVAPQYPSVFGAWMCELIDGPHPTTGTD
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
ALNKEGIFTPYWTKGDDGKMEFSTWSIKPEDEYYSAPLKSGKAIITSPYLTNMKKLVTSV
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCCCCCCEEEECHHHHHHHHHHHHH
SVPMRVNGTVVGLAGVDIKLDDLTAALTEMHPFDGGRVMLLANDGKWLAHPDKDNLMKDY
CCCEEECCEEEEEECCEEEHHHHHHHHHHCCCCCCCEEEEEECCCCEECCCCHHHHHHHH
ADAGAADVKQALADGKMRVISGLPDGAVRLVYPFTARGMNTTWAAVLDVPAATFSAPVWQ
HCCCHHHHHHHHHCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHCCHHHHCCHHHH
QIYNTVIGGVLILAVMLGVILTASRILIGKPLNGILSAVQKMAGGNYREPIDHNGSGDEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
GSLKGALEKFRHQLARGETLKDEQEALQAQVETDRKRQGDLEQAKAEDLRHFVEVVQSRF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DLLASGDLTVRMNETVAPEFETIRANFNTSVSALEDTIRNVVNAVYTIRSGLGEISTASN
HHHCCCCEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHH
DLARRTEQQAASLEETVAALGDVTRGVNDTSDGANSAQQTMKLARADAEKGGEVVARAIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHH
AMTEIQGSSGKIGNIIRVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQR
HHHHHCCCCCCHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
SAQAAKEISGLISMSSSQVQTGVNLVEETGVALSKIVDRVVGMSDTVNEIATSAKAQATS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LREVSAAADLMDKVTQQNAAMVEETTAAAQGLAQETENLAAVVGRFGLGGAMSRGSQAPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCC
AMKLAS
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]