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The map label for this gene is ctaE [H]

Identifier: 209548213

GI number: 209548213

Start: 632394

End: 633272

Strand: Direct

Name: ctaE [H]

Synonym: Rleg2_0607

Alternate gene names: 209548213

Gene position: 632394-633272 (Clockwise)

Preceding gene: 209548212

Following gene: 209548215

Centisome position: 13.94

GC content: 62.12

Gene sequence:

>879_bases
ATGGCCGATGCTCATCAGAAGAATCACGACTATCACATCATCGATCCGAGCCCGTGGCCGATTCTCGCCTCGCTCGGCGC
CTTCATCATGGCGATCGGCGGCGTCTGCTACATGCGCTACCTGAACGGCGGATCGTTCAAGGTCGCCGGCGCCGAACTCG
CGAACCCCTGGCTCTTCTACATCGGCTTCGCACTGGTTCTCTACGTCATGTACGGCTGGTGGGCCGATACGGTGAAGGAA
GCCCATGAGGGCGCCCACACCCGCGTCGTCTCGCTGCACCTGCGCTACGGCATGATCATGTTCATCGCTTCGGAAGTGAT
GTTCTTCGTCGCCTGGTTCTGGGCCTATTTTGACGCCAGCCTCTATCCGAACGAGGCAATCCAGGCCTCGCGCCTGCTCT
ATACCGGCGGCACCTGGCCGCCGAAGGGCATCGAGGTTCTCGATCCCTGGCACCTGCCGATCTACAACACCGTCATCCTG
CTGCTGTCGGGCACGACGGTCACCTGGGCGCACCATGCGCTGCTGCACAACGACCGCAAGGGCCTGATCCAGGGCCTGAC
GCTGACGGTGCTGCTCGGCATTTTCTTCTCCAGCGTCCAGGCCTATGAATATGCCCACGCGCCTTTCGCCTTCAAGAATT
CGATCTACGGCGCGACCTTCTTCATGGCGACCGGCTTCCACGGTTTCCACGTCCTCATCGGCACCATCTTTCTGCTGGTC
TGCCTGATCCGGTCGCTGCGCGGCGATTTCACCCCGAAACAGCATTTCGGCTTCGAGGCGGCCGCCTGGTACTGGCACTT
CGTCGACGTCGTCTGGCTGTTCCTGTTCTTCTGCATCTACGTCTGGGGCGGCTGGGGCGCGCCCGTCGCGGCCGGCTGA

Upstream 100 bases:

>100_bases
AATGAGGGTGGAGCGGTAAAGAGTGAAAAGAAACTTTGATCAAGGCTCGTTTCCGGCTATGCCGGGAACGGAGTGAAGGA
AGACATCCGGGGATAGCTAC

Downstream 100 bases:

>100_bases
TTGCAGCGATATTCAAGGAAAAGGCGGGCCGGGTGCCCGCCTTTTTTGTGTGTGGTCCCCCATGCTCGGTTCTCGTCAGT
CGGGAACGGAGCGGTTGCCG

Product: cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MADAHQKNHDYHIIDPSPWPILASLGAFIMAIGGVCYMRYLNGGSFKVAGAELANPWLFYIGFALVLYVMYGWWADTVKE
AHEGAHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDASLYPNEAIQASRLLYTGGTWPPKGIEVLDPWHLPIYNTVIL
LLSGTTVTWAHHALLHNDRKGLIQGLTLTVLLGIFFSSVQAYEYAHAPFAFKNSIYGATFFMATGFHGFHVLIGTIFLLV
CLIRSLRGDFTPKQHFGFEAAAWYWHFVDVVWLFLFFCIYVWGGWGAPVAAG

Sequences:

>Translated_292_residues
MADAHQKNHDYHIIDPSPWPILASLGAFIMAIGGVCYMRYLNGGSFKVAGAELANPWLFYIGFALVLYVMYGWWADTVKE
AHEGAHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDASLYPNEAIQASRLLYTGGTWPPKGIEVLDPWHLPIYNTVIL
LLSGTTVTWAHHALLHNDRKGLIQGLTLTVLLGIFFSSVQAYEYAHAPFAFKNSIYGATFFMATGFHGFHVLIGTIFLLV
CLIRSLRGDFTPKQHFGFEAAAWYWHFVDVVWLFLFFCIYVWGGWGAPVAAG
>Mature_291_residues
ADAHQKNHDYHIIDPSPWPILASLGAFIMAIGGVCYMRYLNGGSFKVAGAELANPWLFYIGFALVLYVMYGWWADTVKEA
HEGAHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDASLYPNEAIQASRLLYTGGTWPPKGIEVLDPWHLPIYNTVILL
LSGTTVTWAHHALLHNDRKGLIQGLTLTVLLGIFFSSVQAYEYAHAPFAFKNSIYGATFFMATGFHGFHVLIGTIFLLVC
LIRSLRGDFTPKQHFGFEAAAWYWHFVDVVWLFLFFCIYVWGGWGAPVAAG

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=280, Percent_Identity=46.0714285714286, Blast_Score=242, Evalue=4e-64,
Organism=Escherichia coli, GI1786633, Length=177, Percent_Identity=28.8135593220339, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6226542, Length=284, Percent_Identity=33.8028169014084, Blast_Score=166, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 33011; Mature: 32879

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADAHQKNHDYHIIDPSPWPILASLGAFIMAIGGVCYMRYLNGGSFKVAGAELANPWLFY
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCHHHHH
IGFALVLYVMYGWWADTVKEAHEGAHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDAS
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LYPNEAIQASRLLYTGGTWPPKGIEVLDPWHLPIYNTVILLLSGTTVTWAHHALLHNDRK
CCCCHHHHHHHEEEECCCCCCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHH
GLIQGLTLTVLLGIFFSSVQAYEYAHAPFAFKNSIYGATFFMATGFHGFHVLIGTIFLLV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHH
CLIRSLRGDFTPKQHFGFEAAAWYWHFVDVVWLFLFFCIYVWGGWGAPVAAG
HHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ADAHQKNHDYHIIDPSPWPILASLGAFIMAIGGVCYMRYLNGGSFKVAGAELANPWLFY
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCHHHHH
IGFALVLYVMYGWWADTVKEAHEGAHTRVVSLHLRYGMIMFIASEVMFFVAWFWAYFDAS
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LYPNEAIQASRLLYTGGTWPPKGIEVLDPWHLPIYNTVILLLSGTTVTWAHHALLHNDRK
CCCCHHHHHHHEEEECCCCCCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCHH
GLIQGLTLTVLLGIFFSSVQAYEYAHAPFAFKNSIYGATFFMATGFHGFHVLIGTIFLLV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHH
CLIRSLRGDFTPKQHFGFEAAAWYWHFVDVVWLFLFFCIYVWGGWGAPVAAG
HHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]