Click here to switch to the map view.

The map label for this gene is ctaB [H]

Identifier: 209548210

GI number: 209548210

Start: 630637

End: 631587

Strand: Direct

Name: ctaB [H]

Synonym: Rleg2_0604

Alternate gene names: 209548210

Gene position: 630637-631587 (Clockwise)

Preceding gene: 209548209

Following gene: 209548211

Centisome position: 13.9

GC content: 63.3

Gene sequence:

>951_bases
ATGACGGTTATCGACAATCACGGGGCGCTTGCAAAGGACGGCGAATTGTCGGAAGCGAGTGCGCGCGATTATTTCGAATT
GCTGAAGCCGCGGGTGATGTCGCTCGTGGTCTTCACCGCCTTTGCCGGCCTGGTGCTGGCGCCGGGCCACATCCATCCCG
TCCTCGGCCTGATCGCCATTCTCTGTATCGCCGTCGGCGCCGGCGCTTCCGGCGCGCTCAATATGTGGTACGACGCCGAT
ATCGACGCCATCATGAGCCGCACCGCCAAGCGTCCGATCCCGGCCGGCCGCATCGCGCCCTCGGAGGCGCTGGCCTTCGG
CCTGGTGCTATCAGGCTTCTCGGTCGTCATCCTCGGCCTTGCCGTCAACTGGCTCTCGGCCGGCATCCTTGCCTTCACCA
TCTTCTTCTATGCCGTCGTCTACACCATGTGGCTGAAGCGCTCGACGCCGCAGAACATCGTCATCGGCGGCGCTGCCGGC
GCCTTCCCGCCGATGATCGGCTGGGCCTGCGTCACCAACAGCGTGACGATCGAGAGCACCGTTCTCTTCCTGATCATCTT
CCTGTGGACGCCGGCGCACTTCTGGGCGCTGGCTCTGTTCAAGATGCGCGATTACGAGGCCGTCGGCGTGCCGATGCTGC
CGAACGTCGCCGGCGAGCGGGTAACCAAGCATCAGATCGTCGCCTATGCGGTGCTGACCGCGGTTTGCGGGATATTGCCC
TCCTTCCTCGGTTTCGCAAGCTTCGGCTACGGCCTGGTGGCCGCCGCGCTCGGCGCGATCTTCATCTACTGTTCCATCGC
CGTCTGGCGTATGCCCGACGGCGATCTGAAGATGATCCCGGCGAAGAAGCTGTTCGCCTTCTCGATCTTCTATCTTTTCG
CCGTGTTCTCCGCCCTGATGATCGACCGGCTGGCCTCGATCTTCGTCTCGCACACCGGAGGCTGGTTCTGA

Upstream 100 bases:

>100_bases
TCACCAGTGGGAACAGCTTCCGCGCATCAAGTAATTGCGCGGGTATCAGGACGCCGCATTCATTACGGCGTCCTGGTATT
CTGATATTCAGGACGGAATG

Downstream 100 bases:

>100_bases
TGGATCTCGTTAAGCTCACCGAAAAGCAGATGAAGTCGCGCCGCAACCGCAACATCGCCCTTGGGCTGGTGCTCGCCGGC
CTTGTCGTTCTCTTTTACGC

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTVIDNHGALAKDGELSEASARDYFELLKPRVMSLVVFTAFAGLVLAPGHIHPVLGLIAILCIAVGAGASGALNMWYDAD
IDAIMSRTAKRPIPAGRIAPSEALAFGLVLSGFSVVILGLAVNWLSAGILAFTIFFYAVVYTMWLKRSTPQNIVIGGAAG
AFPPMIGWACVTNSVTIESTVLFLIIFLWTPAHFWALALFKMRDYEAVGVPMLPNVAGERVTKHQIVAYAVLTAVCGILP
SFLGFASFGYGLVAAALGAIFIYCSIAVWRMPDGDLKMIPAKKLFAFSIFYLFAVFSALMIDRLASIFVSHTGGWF

Sequences:

>Translated_316_residues
MTVIDNHGALAKDGELSEASARDYFELLKPRVMSLVVFTAFAGLVLAPGHIHPVLGLIAILCIAVGAGASGALNMWYDAD
IDAIMSRTAKRPIPAGRIAPSEALAFGLVLSGFSVVILGLAVNWLSAGILAFTIFFYAVVYTMWLKRSTPQNIVIGGAAG
AFPPMIGWACVTNSVTIESTVLFLIIFLWTPAHFWALALFKMRDYEAVGVPMLPNVAGERVTKHQIVAYAVLTAVCGILP
SFLGFASFGYGLVAAALGAIFIYCSIAVWRMPDGDLKMIPAKKLFAFSIFYLFAVFSALMIDRLASIFVSHTGGWF
>Mature_315_residues
TVIDNHGALAKDGELSEASARDYFELLKPRVMSLVVFTAFAGLVLAPGHIHPVLGLIAILCIAVGAGASGALNMWYDADI
DAIMSRTAKRPIPAGRIAPSEALAFGLVLSGFSVVILGLAVNWLSAGILAFTIFFYAVVYTMWLKRSTPQNIVIGGAAGA
FPPMIGWACVTNSVTIESTVLFLIIFLWTPAHFWALALFKMRDYEAVGVPMLPNVAGERVTKHQIVAYAVLTAVCGILPS
FLGFASFGYGLVAAALGAIFIYCSIAVWRMPDGDLKMIPAKKLFAFSIFYLFAVFSALMIDRLASIFVSHTGGWF

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=188, Percent_Identity=33.5106382978723, Blast_Score=95, Evalue=6e-20,
Organism=Escherichia coli, GI1786631, Length=284, Percent_Identity=29.5774647887324, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71998235, Length=269, Percent_Identity=27.8810408921933, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325085, Length=193, Percent_Identity=31.0880829015544, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921064, Length=294, Percent_Identity=27.2108843537415, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33926; Mature: 33794

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVIDNHGALAKDGELSEASARDYFELLKPRVMSLVVFTAFAGLVLAPGHIHPVLGLIAI
CCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LCIAVGAGASGALNMWYDADIDAIMSRTAKRPIPAGRIAPSEALAFGLVLSGFSVVILGL
HHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVNWLSAGILAFTIFFYAVVYTMWLKRSTPQNIVIGGAAGAFPPMIGWACVTNSVTIEST
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCHHHH
VLFLIIFLWTPAHFWALALFKMRDYEAVGVPMLPNVAGERVTKHQIVAYAVLTAVCGILP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SFLGFASFGYGLVAAALGAIFIYCSIAVWRMPDGDLKMIPAKKLFAFSIFYLFAVFSALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEECCHHHHHHHHHHHHHHHHHHHH
IDRLASIFVSHTGGWF
HHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVIDNHGALAKDGELSEASARDYFELLKPRVMSLVVFTAFAGLVLAPGHIHPVLGLIAI
CEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LCIAVGAGASGALNMWYDADIDAIMSRTAKRPIPAGRIAPSEALAFGLVLSGFSVVILGL
HHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVNWLSAGILAFTIFFYAVVYTMWLKRSTPQNIVIGGAAGAFPPMIGWACVTNSVTIEST
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCHHHH
VLFLIIFLWTPAHFWALALFKMRDYEAVGVPMLPNVAGERVTKHQIVAYAVLTAVCGILP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SFLGFASFGYGLVAAALGAIFIYCSIAVWRMPDGDLKMIPAKKLFAFSIFYLFAVFSALM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEECCHHHHHHHHHHHHHHHHHHHH
IDRLASIFVSHTGGWF
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA