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The map label for this gene is ctaD [H]

Identifier: 209548209

GI number: 209548209

Start: 628873

End: 630570

Strand: Direct

Name: ctaD [H]

Synonym: Rleg2_0603

Alternate gene names: 209548209

Gene position: 628873-630570 (Clockwise)

Preceding gene: 209548208

Following gene: 209548210

Centisome position: 13.86

GC content: 61.6

Gene sequence:

>1698_bases
ATGGCTGGACCTTCCGCTCACGACGATCATTCTCATGATCACGCCCATCACGACCACGCTCATGATGACCACGATCACGG
GCACAAGCCGAGCTTTGCCAATCGTTGGCTGTTCTCGACCAACCACAAGGACATCGGCACGCTCTACCTGATCTTCGCGA
TCATTGCCGGCATCATCGGCGGCGCATTGTCCGTCGCCATGCGCATGGAGCTGCAGGAGCCTGGCATCCAGATCTTCCAC
GGCCTGGCCTCGATGGTCTACGGCTATGAGGGCGATGCCGCGATCGACGGCGCCAAGCAGATGTTCAACATGTTCACGAC
AGCGCATGCGCTGATCATGATCTTCTTCATGGTCATGCCGGCGATGATCGGCGGTTTTGCCAACTGGATGGTGCCGATCA
TGATCGGCGCGCCCGACATGGCCTTCCCGCGCCTGAACAACATCTCCTTCTGGCTGATCGTTCCGGCCTTCGCGCTGCTC
CTGCTGTCGATGTTCGTCGAAGGCCCGGCAGGCGCCTACGGCACGGGCGGCGGCTGGACGATGTATCCGCCGCTGGCGAC
CAGCGGCACGCCGGGACCGGCAGTCGACCTGGCGATCTTTGCGCTCCATATCGCCGGCGCCTCGTCGATCCTCGGTGCGA
TCAACTTCATCACCACGATCCTCAACATGCGCGCCCCCGGCATGACGCTGCACAAGATGCCGCTGTTTGCCTGGTCGGTG
CTGATCACCGCCTTCCTGCTGCTGCTGTCGCTGCCGGTTCTGGCAGGCGGCATCACCATGCTGCTCACCGACCGTAACTT
CGGCACCTCCTTCTTCTCTCCGGAAGGCGGCGGCGACCCGATCCTCTACCAGCACCTGTTCTGGTTCTTCGGTCACCCCG
AGGTCTACATCCTCATCCTGCCCGGCTTCGGCATGGTCAGCCATATCATCTCGACCTTCTCGAAGAAGCCGATCTTCGGT
TATCTCGGCATGGCCTACGCCATGGTCGCGATCGGTGCCGTCGGCTTCGTCGTCTGGGCCCACCACATGTACACGGTCGG
CCTGTCGCTCGACGCGCAGCGCTACTTCGTTTTCGCGACGATGGTCATCGCCGTTCCGACGGGTGTGAAGATCTTCTCCT
GGATCGCGACGATGTGGGGCGGCTCGATCTCGTTCCGCACGCCGATGCTCTGGGCGATCGGCTTCATCTTCCTGTTCACG
GTCGGCGGCGTCACCGGCGTCCAGCTCGCCAATGCCGGTCTCGACCGTTCGCTGCATGACACCTATTACGTCGTGGCTCA
CTTCCACTACGTTCTGTCGCTCGGCGCCGTCTTCGCGATCTTCGCCGGCTGGTACTACTGGTTCCCGAAGATGACCGGCT
ACATGTACAACGAGTTGGTCGGCAAGCTGCATTTCTGGGTCATGTTCATCGGCGTCAACCTGGTGTTCTTCCCGCAGCAC
TTCCTCGGCCTCGCCGGCATGCCGCGTCGCTACATCGACTATCCGGATGCCTTTGCCGGCTGGAACTATGTGTCCTCGAT
CGGCTCCTATATCTCGGCCTTCGGTGTGCTGATCTTCCTCTTCGGCGTCTTCGAAGCCTTCGCCAAGAAGCGCGTCGCCG
GCGACAATCCATGGGGTGAGGGTGCGACGACGCTCGAATGGCAGCTGCCTTCGCCGCCGCCCTATCACCAGTGGGAACAG
CTTCCGCGCATCAAGTAA

Upstream 100 bases:

>100_bases
GCGACCTGCCCGGCGCCTACAAGACACTCATGGCCGCAACCGATGGTCCCGCAAAGACCCTCGACGTCGCCGAAGCACAG
TAATTAAGGGGATCGGGACA

Downstream 100 bases:

>100_bases
TTGCGCGGGTATCAGGACGCCGCATTCATTACGGCGTCCTGGTATTCTGATATTCAGGACGGAATGATGACGGTTATCGA
CAATCACGGGGCGCTTGCAA

Product: cytochrome C oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MAGPSAHDDHSHDHAHHDHAHDDHDHGHKPSFANRWLFSTNHKDIGTLYLIFAIIAGIIGGALSVAMRMELQEPGIQIFH
GLASMVYGYEGDAAIDGAKQMFNMFTTAHALIMIFFMVMPAMIGGFANWMVPIMIGAPDMAFPRLNNISFWLIVPAFALL
LLSMFVEGPAGAYGTGGGWTMYPPLATSGTPGPAVDLAIFALHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSV
LITAFLLLLSLPVLAGGITMLLTDRNFGTSFFSPEGGGDPILYQHLFWFFGHPEVYILILPGFGMVSHIISTFSKKPIFG
YLGMAYAMVAIGAVGFVVWAHHMYTVGLSLDAQRYFVFATMVIAVPTGVKIFSWIATMWGGSISFRTPMLWAIGFIFLFT
VGGVTGVQLANAGLDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMTGYMYNELVGKLHFWVMFIGVNLVFFPQH
FLGLAGMPRRYIDYPDAFAGWNYVSSIGSYISAFGVLIFLFGVFEAFAKKRVAGDNPWGEGATTLEWQLPSPPPYHQWEQ
LPRIK

Sequences:

>Translated_565_residues
MAGPSAHDDHSHDHAHHDHAHDDHDHGHKPSFANRWLFSTNHKDIGTLYLIFAIIAGIIGGALSVAMRMELQEPGIQIFH
GLASMVYGYEGDAAIDGAKQMFNMFTTAHALIMIFFMVMPAMIGGFANWMVPIMIGAPDMAFPRLNNISFWLIVPAFALL
LLSMFVEGPAGAYGTGGGWTMYPPLATSGTPGPAVDLAIFALHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSV
LITAFLLLLSLPVLAGGITMLLTDRNFGTSFFSPEGGGDPILYQHLFWFFGHPEVYILILPGFGMVSHIISTFSKKPIFG
YLGMAYAMVAIGAVGFVVWAHHMYTVGLSLDAQRYFVFATMVIAVPTGVKIFSWIATMWGGSISFRTPMLWAIGFIFLFT
VGGVTGVQLANAGLDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMTGYMYNELVGKLHFWVMFIGVNLVFFPQH
FLGLAGMPRRYIDYPDAFAGWNYVSSIGSYISAFGVLIFLFGVFEAFAKKRVAGDNPWGEGATTLEWQLPSPPPYHQWEQ
LPRIK
>Mature_564_residues
AGPSAHDDHSHDHAHHDHAHDDHDHGHKPSFANRWLFSTNHKDIGTLYLIFAIIAGIIGGALSVAMRMELQEPGIQIFHG
LASMVYGYEGDAAIDGAKQMFNMFTTAHALIMIFFMVMPAMIGGFANWMVPIMIGAPDMAFPRLNNISFWLIVPAFALLL
LSMFVEGPAGAYGTGGGWTMYPPLATSGTPGPAVDLAIFALHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSVL
ITAFLLLLSLPVLAGGITMLLTDRNFGTSFFSPEGGGDPILYQHLFWFFGHPEVYILILPGFGMVSHIISTFSKKPIFGY
LGMAYAMVAIGAVGFVVWAHHMYTVGLSLDAQRYFVFATMVIAVPTGVKIFSWIATMWGGSISFRTPMLWAIGFIFLFTV
GGVTGVQLANAGLDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMTGYMYNELVGKLHFWVMFIGVNLVFFPQHF
LGLAGMPRRYIDYPDAFAGWNYVSSIGSYISAFGVLIFLFGVFEAFAKKRVAGDNPWGEGATTLEWQLPSPPPYHQWEQL
PRIK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=531, Percent_Identity=61.9585687382298, Blast_Score=614, Evalue=1e-176,
Organism=Escherichia coli, GI1786634, Length=536, Percent_Identity=41.6044776119403, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226519, Length=548, Percent_Identity=55.2919708029197, Blast_Score=600, Evalue=1e-172,
Organism=Saccharomyces cerevisiae, GI6226524, Length=344, Percent_Identity=59.0116279069767, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6226523, Length=267, Percent_Identity=53.9325842696629, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6226522, Length=94, Percent_Identity=39.3617021276596, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6226521, Length=81, Percent_Identity=40.7407407407407, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 62310; Mature: 62178

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGPSAHDDHSHDHAHHDHAHDDHDHGHKPSFANRWLFSTNHKDIGTLYLIFAIIAGIIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHHH
GALSVAMRMELQEPGIQIFHGLASMVYGYEGDAAIDGAKQMFNMFTTAHALIMIFFMVMP
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIGGFANWMVPIMIGAPDMAFPRLNNISFWLIVPAFALLLLSMFVEGPAGAYGTGGGWT
HHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
MYPPLATSGTPGPAVDLAIFALHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSV
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LITAFLLLLSLPVLAGGITMLLTDRNFGTSFFSPEGGGDPILYQHLFWFFGHPEVYILIL
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEE
PGFGMVSHIISTFSKKPIFGYLGMAYAMVAIGAVGFVVWAHHMYTVGLSLDAQRYFVFAT
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
MVIAVPTGVKIFSWIATMWGGSISFRTPMLWAIGFIFLFTVGGVTGVQLANAGLDRSLHD
HHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHH
TYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMTGYMYNELVGKLHFWVMFIGVNLVFFPQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLAGMPRRYIDYPDAFAGWNYVSSIGSYISAFGVLIFLFGVFEAFAKKRVAGDNPWGE
HHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GATTLEWQLPSPPPYHQWEQLPRIK
CCCEEEEECCCCCCCHHHHHCCCCC
>Mature Secondary Structure 
AGPSAHDDHSHDHAHHDHAHDDHDHGHKPSFANRWLFSTNHKDIGTLYLIFAIIAGIIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCEEECCCCCHHHHHHHHHHHHHHHH
GALSVAMRMELQEPGIQIFHGLASMVYGYEGDAAIDGAKQMFNMFTTAHALIMIFFMVMP
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMIGGFANWMVPIMIGAPDMAFPRLNNISFWLIVPAFALLLLSMFVEGPAGAYGTGGGWT
HHHHHHHHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
MYPPLATSGTPGPAVDLAIFALHIAGASSILGAINFITTILNMRAPGMTLHKMPLFAWSV
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LITAFLLLLSLPVLAGGITMLLTDRNFGTSFFSPEGGGDPILYQHLFWFFGHPEVYILIL
HHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEE
PGFGMVSHIISTFSKKPIFGYLGMAYAMVAIGAVGFVVWAHHMYTVGLSLDAQRYFVFAT
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
MVIAVPTGVKIFSWIATMWGGSISFRTPMLWAIGFIFLFTVGGVTGVQLANAGLDRSLHD
HHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHH
TYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMTGYMYNELVGKLHFWVMFIGVNLVFFPQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLAGMPRRYIDYPDAFAGWNYVSSIGSYISAFGVLIFLFGVFEAFAKKRVAGDNPWGE
HHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GATTLEWQLPSPPPYHQWEQLPRIK
CCCEEEEECCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]