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The map label for this gene is fadB1 [H]

Identifier: 209548162

GI number: 209548162

Start: 578116

End: 578871

Strand: Direct

Name: fadB1 [H]

Synonym: Rleg2_0556

Alternate gene names: 209548162

Gene position: 578116-578871 (Clockwise)

Preceding gene: 209548161

Following gene: 209548165

Centisome position: 12.74

GC content: 66.93

Gene sequence:

>756_bases
ATGACCGATCACATCATCGTCGAGCAGCCTTCCGCCCATCCCGGCGTCCAGCTCATCCGCTTCAACCGGCCGGAGAAGAA
GAACGCCATCACCCGCGCCATGTATCGTACCATGGCCGATGCGCTGAAGGCGGCCGATGCCGATACGACCATCCGCGCCA
CCGCCTTTCTCGGCACCGAAGGCTGCTTTTCTTCAGGCAATGATCTGAACGACTTCCTTGCCGCCGCAGTCGGCGGCGGC
GGCCTCGAGCAGGAGATTCTCGATTTCCTCTATGCGCTGGTGAAGGCCGAAAAACCTGTGATCTCCGGCGTCGACGGTCT
GGCGATCGGCATCGGCACGACGATCCACCTCCATTGCGACCTGACGATCGCCTCGAGCCGCAGCCAGTTCCGCACCCCCT
TCGTCGATCTGGCGCTGGTGCCGGAGGCGGGGTCGAGCCTCGTTGCGCCGCGGCTGATGGGCCAGCAGCGCGCCTTCGCC
CTGCTGGCGGCCGGCGAAGGCTTTTCGGCGGCCGAGGCCAAGGACGCCGGCATCATCTGGAAAGTGGTCGAACCCGGCGA
GGTCGATGCCGTAACGCTGGCGACCGCCGCCCGGCTCGCCGCCAAACCGCCGGAAGCGCTGCGCATTGCCCGCGATCTCA
TCCGCGGCGACAGCGGCGAGATCATCGCCCGCATCGACGAGGAGGCCCGCCACTTCTCCGCCCGCCTGAAAAGCGCCGAG
GCCCGCGCCGCCTTCGAAGCCTTCATGCGTCGCTAG

Upstream 100 bases:

>100_bases
CCGCAGCCCTTCGCGACCGCGTCGTCAATGGCGCGGCAAGCCTTGCCGCCGCCCGCATCCTGCTTGCCTGAGGCGACCCC
ATGACCTCTGAGGACATCCA

Downstream 100 bases:

>100_bases
AGCATGGGCACATCGAAGATCTCACCGGCCCTGAGCGGCCGGAACCGGTCCGCAGCAATATCGTGCTCGCGCATCGCCTC
TTGCAACGCCTTTACCGGTG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MTDHIIVEQPSAHPGVQLIRFNRPEKKNAITRAMYRTMADALKAADADTTIRATAFLGTEGCFSSGNDLNDFLAAAVGGG
GLEQEILDFLYALVKAEKPVISGVDGLAIGIGTTIHLHCDLTIASSRSQFRTPFVDLALVPEAGSSLVAPRLMGQQRAFA
LLAAGEGFSAAEAKDAGIIWKVVEPGEVDAVTLATAARLAAKPPEALRIARDLIRGDSGEIIARIDEEARHFSARLKSAE
ARAAFEAFMRR

Sequences:

>Translated_251_residues
MTDHIIVEQPSAHPGVQLIRFNRPEKKNAITRAMYRTMADALKAADADTTIRATAFLGTEGCFSSGNDLNDFLAAAVGGG
GLEQEILDFLYALVKAEKPVISGVDGLAIGIGTTIHLHCDLTIASSRSQFRTPFVDLALVPEAGSSLVAPRLMGQQRAFA
LLAAGEGFSAAEAKDAGIIWKVVEPGEVDAVTLATAARLAAKPPEALRIARDLIRGDSGEIIARIDEEARHFSARLKSAE
ARAAFEAFMRR
>Mature_250_residues
TDHIIVEQPSAHPGVQLIRFNRPEKKNAITRAMYRTMADALKAADADTTIRATAFLGTEGCFSSGNDLNDFLAAAVGGGG
LEQEILDFLYALVKAEKPVISGVDGLAIGIGTTIHLHCDLTIASSRSQFRTPFVDLALVPEAGSSLVAPRLMGQQRAFAL
LAAGEGFSAAEAKDAGIIWKVVEPGEVDAVTLATAARLAAKPPEALRIARDLIRGDSGEIIARIDEEARHFSARLKSAEA
RAAFEAFMRR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI260274832, Length=249, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI45643119, Length=249, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI260275230, Length=249, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI68989263, Length=203, Percent_Identity=33.4975369458128, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI25453481, Length=243, Percent_Identity=26.3374485596708, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI51538573, Length=243, Percent_Identity=26.3374485596708, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4757966, Length=207, Percent_Identity=28.0193236714976, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI51538581, Length=207, Percent_Identity=28.0193236714976, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI194097323, Length=181, Percent_Identity=28.1767955801105, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI4757968, Length=243, Percent_Identity=26.3374485596708, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI49355787, Length=243, Percent_Identity=26.3374485596708, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI221136756, Length=200, Percent_Identity=25.5, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI221136753, Length=200, Percent_Identity=25.5, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI221307494, Length=197, Percent_Identity=25.8883248730964, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI116235487, Length=207, Percent_Identity=25.1207729468599, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI20127408, Length=176, Percent_Identity=26.7045454545455, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31542718, Length=193, Percent_Identity=30.0518134715026, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI70995211, Length=194, Percent_Identity=26.2886597938144, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787660, Length=241, Percent_Identity=31.1203319502075, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=27.906976744186, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788597, Length=208, Percent_Identity=26.4423076923077, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17535521, Length=245, Percent_Identity=33.469387755102, Blast_Score=133, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17554946, Length=238, Percent_Identity=27.3109243697479, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=203, Percent_Identity=31.5270935960591, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=24.5967741935484, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=235, Percent_Identity=26.3829787234043, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=212, Percent_Identity=26.8867924528302, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24654903, Length=236, Percent_Identity=29.6610169491525, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=22.4, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=22.4, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653139, Length=200, Percent_Identity=30.5, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21357171, Length=232, Percent_Identity=25.8620689655172, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920382, Length=218, Percent_Identity=26.605504587156, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26727; Mature: 26596

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHIIVEQPSAHPGVQLIRFNRPEKKNAITRAMYRTMADALKAADADTTIRATAFLGTE
CCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
GCFSSGNDLNDFLAAAVGGGGLEQEILDFLYALVKAEKPVISGVDGLAIGIGTTIHLHCD
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHCCCCCEEEEECCEEEEEEE
LTIASSRSQFRTPFVDLALVPEAGSSLVAPRLMGQQRAFALLAAGEGFSAAEAKDAGIIW
EEEECCCCHHCCCCEEEEECCCCCCCHHHHHHHCCHHEEEEEECCCCCCCCCCCCCCEEE
KVVEPGEVDAVTLATAARLAAKPPEALRIARDLIRGDSGEIIARIDEEARHFSARLKSAE
EEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHH
ARAAFEAFMRR
HHHHHHHHHCC
>Mature Secondary Structure 
TDHIIVEQPSAHPGVQLIRFNRPEKKNAITRAMYRTMADALKAADADTTIRATAFLGTE
CCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
GCFSSGNDLNDFLAAAVGGGGLEQEILDFLYALVKAEKPVISGVDGLAIGIGTTIHLHCD
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHCCCCCEEEEECCEEEEEEE
LTIASSRSQFRTPFVDLALVPEAGSSLVAPRLMGQQRAFALLAAGEGFSAAEAKDAGIIW
EEEECCCCHHCCCCEEEEECCCCCCCHHHHHHHCCHHEEEEEECCCCCCCCCCCCCCEEE
KVVEPGEVDAVTLATAARLAAKPPEALRIARDLIRGDSGEIIARIDEEARHFSARLKSAE
EEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHH
ARAAFEAFMRR
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]