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The map label for this gene is atpB [H]

Identifier: 209548118

GI number: 209548118

Start: 528350

End: 529102

Strand: Direct

Name: atpB [H]

Synonym: Rleg2_0512

Alternate gene names: 209548118

Gene position: 528350-529102 (Clockwise)

Preceding gene: 209548117

Following gene: 209548119

Centisome position: 11.64

GC content: 57.64

Gene sequence:

>753_bases
GTGTCCAACGATCCGACTCATCAGTTCCAGATCTTCAAGATTGTGCCGATCGAAATCGGCGGAATTGATTTTTCGTTCAC
CAACGCATCGCTCTTCATGGCAGCGTCCGCTGCCGTGGCCGTCGGCTTCCTCTATTTCGCGACCTCGAACCGCGCCATCG
TGCCGGGCCGTTCGCAGTCGGTTGCGGAAATGTCCTATGAATTCATCGCCAACATGCTGAAGGAAGGCGCGGGCAAGCAG
GGGATGAAGTTCTTCCCGCTGGTCTTCTCGCTCTTCATGTTCGTGCTGACGGCGAACCTGCTCGGCATGTTCCCGTATTT
CTTCACGATCACCAGCCAGATCATCGTCACCTTCGCGCTGGCGATCCTCGTCATTGGCACGGTTCTCGTCTATGGTTTCT
ATAAGCACGGCTTCCACTTCCTGAATGTCTTCGTGCCCTCGGGCGTGCCGGGCATATTGCTGCCGCTGGTCGTCTCGATC
GAAATCATTTCCTTCCTGTCCCGTCCGATTTCGCTCTCCGTTCGTCTTTTCGCCAACATGCTCGCCGGTCATATCACGCT
GAAGGTGTTCGCAGGCTTCGTCGCCTCGCTTGGAGCCCTCGGTGCGGTCGGTGTCGGCGGCGCAGTTCTTCCCCTCATCA
TGACCGTCGCCCTGACCGGTCTCGAGTTCCTCGTCGCCTTCCTTCAGGCTTACGTCTTTGCGGTGCTGACTTGCATGTAC
CTCAACGACGCAATCCATCCGGGCGGGCACTAA

Upstream 100 bases:

>100_bases
GGGTGGTGGCCCATCCCCTTGATGACGACAAGAAATAAGGACCGGTTCCCGGTCCAGTGCAATGACCCCGCGTCCTGCGG
GCCAAAGAGAGAGAACAGCG

Downstream 100 bases:

>100_bases
GGATAACGACAACGACGTCTCCAGGGCGTCAGTCATTCGCCGCAACAACCATTTCAAAGGAGTTCAACATGGAAGCGGAA
GCAGCAAAGTTCATCGGTGC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSNDPTHQFQIFKIVPIEIGGIDFSFTNASLFMAASAAVAVGFLYFATSNRAIVPGRSQSVAEMSYEFIANMLKEGAGKQ
GMKFFPLVFSLFMFVLTANLLGMFPYFFTITSQIIVTFALAILVIGTVLVYGFYKHGFHFLNVFVPSGVPGILLPLVVSI
EIISFLSRPISLSVRLFANMLAGHITLKVFAGFVASLGALGAVGVGGAVLPLIMTVALTGLEFLVAFLQAYVFAVLTCMY
LNDAIHPGGH

Sequences:

>Translated_250_residues
MSNDPTHQFQIFKIVPIEIGGIDFSFTNASLFMAASAAVAVGFLYFATSNRAIVPGRSQSVAEMSYEFIANMLKEGAGKQ
GMKFFPLVFSLFMFVLTANLLGMFPYFFTITSQIIVTFALAILVIGTVLVYGFYKHGFHFLNVFVPSGVPGILLPLVVSI
EIISFLSRPISLSVRLFANMLAGHITLKVFAGFVASLGALGAVGVGGAVLPLIMTVALTGLEFLVAFLQAYVFAVLTCMY
LNDAIHPGGH
>Mature_249_residues
SNDPTHQFQIFKIVPIEIGGIDFSFTNASLFMAASAAVAVGFLYFATSNRAIVPGRSQSVAEMSYEFIANMLKEGAGKQG
MKFFPLVFSLFMFVLTANLLGMFPYFFTITSQIIVTFALAILVIGTVLVYGFYKHGFHFLNVFVPSGVPGILLPLVVSIE
IISFLSRPISLSVRLFANMLAGHITLKVFAGFVASLGALGAVGVGGAVLPLIMTVALTGLEFLVAFLQAYVFAVLTCMYL
NDAIHPGGH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Homo sapiens, GI251831112, Length=195, Percent_Identity=31.2820512820513, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6226527, Length=247, Percent_Identity=35.6275303643725, Blast_Score=145, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 26872; Mature: 26741

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNDPTHQFQIFKIVPIEIGGIDFSFTNASLFMAASAAVAVGFLYFATSNRAIVPGRSQS
CCCCCCCCEEEEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHH
VAEMSYEFIANMLKEGAGKQGMKFFPLVFSLFMFVLTANLLGMFPYFFTITSQIIVTFAL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILVIGTVLVYGFYKHGFHFLNVFVPSGVPGILLPLVVSIEIISFLSRPISLSVRLFANM
HHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LAGHITLKVFAGFVASLGALGAVGVGGAVLPLIMTVALTGLEFLVAFLQAYVFAVLTCMY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNDAIHPGGH
HHHCCCCCCC
>Mature Secondary Structure 
SNDPTHQFQIFKIVPIEIGGIDFSFTNASLFMAASAAVAVGFLYFATSNRAIVPGRSQS
CCCCCCCEEEEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHH
VAEMSYEFIANMLKEGAGKQGMKFFPLVFSLFMFVLTANLLGMFPYFFTITSQIIVTFAL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILVIGTVLVYGFYKHGFHFLNVFVPSGVPGILLPLVVSIEIISFLSRPISLSVRLFANM
HHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LAGHITLKVFAGFVASLGALGAVGVGGAVLPLIMTVALTGLEFLVAFLQAYVFAVLTCMY
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNDAIHPGGH
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA