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The map label for this gene is dhaR [H]

Identifier: 209548087

GI number: 209548087

Start: 492334

End: 492951

Strand: Reverse

Name: dhaR [H]

Synonym: Rleg2_0480

Alternate gene names: 209548087

Gene position: 492951-492334 (Counterclockwise)

Preceding gene: 209548090

Following gene: 209548083

Centisome position: 10.86

GC content: 59.87

Gene sequence:

>618_bases
ATGGAAACGCAAACCAAAGCGGCCCGCCGCGGGCCCAAGCCAAACCCGAATACGCGGGATAATCTCATGCGTGTCGGGGT
GCAAATGCTCCACGAAGCAGGGTACACAGCGACCGGGATCAAGGACATCGTCGACGCCGCGCATGTGCCCAAGGGCTCGT
TCTACAATCACTTCGAAAGCAAGGAAGCCTTCGGAAAAGAGGTGGTCGACTTCTATTTCGATGGCGGCCTTGTCGAGCTG
CGTGCGCGCCTTTGCGATGACAGCATTCCGCCGATCGATCGTCTGCGCGGCTATTTTGACGAGAGGATTCGCGGCTTTCA
GGCAACCGACTATGTGCGTGGCTGCATGCTCGGGAACCTCAGCCTCGAGGTCGCCGACCACAGCGTCCCGATTCGCGACC
GGCTCGCCGCGCATTTCGGGACATGGAGCGGTCTTTTCGAAGCATGCATTGCCGAAGCGCAGAGCGCAGGTGCCATCAGC
AATCGGCTGCCTGCGCCGCTGCTTGCCGAATTCCTGCTCAACAGTTGGGAAGGCGCATTGCTGCGCATGCGCGTGGAGAA
GAGCGATGAGCCGCTGAGAGCATTTGTCGAAGTCGCCTTCGGGTCTCTTCTCATCTGA

Upstream 100 bases:

>100_bases
GGCAGCTGTCAGCGTTCGACCCCGCCAACCTTGACAAACAGCAAAACGCTGCCGAAATACAAGACGACCGGTCACACTTT
TACACGGCAGATCCAAGCAG

Downstream 100 bases:

>100_bases
CTGAAGAGGCCATTACCTCTTCAGCCGCGCCTCGATCTCGCGGTCGAGGGCGAATTTCAGCTCGTCCTTGACGCCGATCG
ACATGGCCAGGACTTCGCGG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
METQTKAARRGPKPNPNTRDNLMRVGVQMLHEAGYTATGIKDIVDAAHVPKGSFYNHFESKEAFGKEVVDFYFDGGLVEL
RARLCDDSIPPIDRLRGYFDERIRGFQATDYVRGCMLGNLSLEVADHSVPIRDRLAAHFGTWSGLFEACIAEAQSAGAIS
NRLPAPLLAEFLLNSWEGALLRMRVEKSDEPLRAFVEVAFGSLLI

Sequences:

>Translated_205_residues
METQTKAARRGPKPNPNTRDNLMRVGVQMLHEAGYTATGIKDIVDAAHVPKGSFYNHFESKEAFGKEVVDFYFDGGLVEL
RARLCDDSIPPIDRLRGYFDERIRGFQATDYVRGCMLGNLSLEVADHSVPIRDRLAAHFGTWSGLFEACIAEAQSAGAIS
NRLPAPLLAEFLLNSWEGALLRMRVEKSDEPLRAFVEVAFGSLLI
>Mature_205_residues
METQTKAARRGPKPNPNTRDNLMRVGVQMLHEAGYTATGIKDIVDAAHVPKGSFYNHFESKEAFGKEVVDFYFDGGLVEL
RARLCDDSIPPIDRLRGYFDERIRGFQATDYVRGCMLGNLSLEVADHSVPIRDRLAAHFGTWSGLFEACIAEAQSAGAIS
NRLPAPLLAEFLLNSWEGALLRMRVEKSDEPLRAFVEVAFGSLLI

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=176, Percent_Identity=27.8409090909091, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22774; Mature: 22774

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQTKAARRGPKPNPNTRDNLMRVGVQMLHEAGYTATGIKDIVDAAHVPKGSFYNHFES
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHH
KEAFGKEVVDFYFDGGLVELRARLCDDSIPPIDRLRGYFDERIRGFQATDYVRGCMLGNL
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
SLEVADHSVPIRDRLAAHFGTWSGLFEACIAEAQSAGAISNRLPAPLLAEFLLNSWEGAL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCHHH
LRMRVEKSDEPLRAFVEVAFGSLLI
EEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
METQTKAARRGPKPNPNTRDNLMRVGVQMLHEAGYTATGIKDIVDAAHVPKGSFYNHFES
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHH
KEAFGKEVVDFYFDGGLVELRARLCDDSIPPIDRLRGYFDERIRGFQATDYVRGCMLGNL
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
SLEVADHSVPIRDRLAAHFGTWSGLFEACIAEAQSAGAISNRLPAPLLAEFLLNSWEGAL
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCHHH
LRMRVEKSDEPLRAFVEVAFGSLLI
EEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]