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The map label for this gene is yfhC [C]

Identifier: 209548083

GI number: 209548083

Start: 488288

End: 488725

Strand: Reverse

Name: yfhC [C]

Synonym: Rleg2_0476

Alternate gene names: 209548083

Gene position: 488725-488288 (Counterclockwise)

Preceding gene: 209548087

Following gene: 209548078

Centisome position: 10.77

GC content: 63.01

Gene sequence:

>438_bases
ATGGAGATGGCGCTCGAAGAGGCACGCGCCGCCGGAGAACGCGGCGAGGTGCCGATCGGCGCCGTCGTCGTCATCGACGA
TATCGCGGTTTCGCGCTCGGGAAATCGCACGCGCGAGCTCAATGACGTGACCGCACATGCCGAAATCGCCGCGATCCGGC
TGGCCTGCGAAGGACTCGGCCAGGAGCGTCTTGTCGGCGCCGATCTCTATGTGACGCTCGAGCCTTGCACCATGTGCGCG
GCAGCCATCTCGTTTGCGCGTATCCGCAGGCTCTATTACGGCGCCGAGGATCCGAAAGGCGGCGGCGTCGACAATGGCGT
GCGATTTTATGCGCAGCCGACCTGCCACCACGCACCGGAAGTCTATTCCGGCTTCAACGAGGTGCAATCGGCCGAGATTC
TTCGCACATTCTTTTCGCAAAAGAGAGAGGCGCCGTAG

Upstream 100 bases:

>100_bases
TGGGTGTCATTTGTTGTTTGCCTGCCTTTTGGGCCTGTCTATCAGGTCACGCATCTGCGGTTAAGTGGAAATTCTTGCGA
TCGTGAAGACAAATCGTTTC

Downstream 100 bases:

>100_bases
CCTGAGGCGCGCGCCACTGCCGCCGGTTTGCGCCGAAGGCTGCCCCTCACCCTAACCCTCTCCCCGTAAAAACGGGGCGA
GGGGACGTGCCCTACGAGAG

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MEMALEEARAAGERGEVPIGAVVVIDDIAVSRSGNRTRELNDVTAHAEIAAIRLACEGLGQERLVGADLYVTLEPCTMCA
AAISFARIRRLYYGAEDPKGGGVDNGVRFYAQPTCHHAPEVYSGFNEVQSAEILRTFFSQKREAP

Sequences:

>Translated_145_residues
MEMALEEARAAGERGEVPIGAVVVIDDIAVSRSGNRTRELNDVTAHAEIAAIRLACEGLGQERLVGADLYVTLEPCTMCA
AAISFARIRRLYYGAEDPKGGGVDNGVRFYAQPTCHHAPEVYSGFNEVQSAEILRTFFSQKREAP
>Mature_145_residues
MEMALEEARAAGERGEVPIGAVVVIDDIAVSRSGNRTRELNDVTAHAEIAAIRLACEGLGQERLVGADLYVTLEPCTMCA
AAISFARIRRLYYGAEDPKGGGVDNGVRFYAQPTCHHAPEVYSGFNEVQSAEILRTFFSQKREAP

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=149, Percent_Identity=30.2013422818792, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI145693172, Length=143, Percent_Identity=38.4615384615385, Blast_Score=97, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17541138, Length=143, Percent_Identity=35.6643356643357, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=96, Percent_Identity=39.5833333333333, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=33.1081081081081, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15730; Mature: 15730

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMALEEARAAGERGEVPIGAVVVIDDIAVSRSGNRTRELNDVTAHAEIAAIRLACEGLG
CCCCHHHHHHCCCCCCCCEEEEEEEECEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
QERLVGADLYVTLEPCTMCAAAISFARIRRLYYGAEDPKGGGVDNGVRFYAQPTCHHAPE
CCCEECCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCH
VYSGFNEVQSAEILRTFFSQKREAP
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEMALEEARAAGERGEVPIGAVVVIDDIAVSRSGNRTRELNDVTAHAEIAAIRLACEGLG
CCCCHHHHHHCCCCCCCCEEEEEEEECEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
QERLVGADLYVTLEPCTMCAAAISFARIRRLYYGAEDPKGGGVDNGVRFYAQPTCHHAPE
CCCEECCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCH
VYSGFNEVQSAEILRTFFSQKREAP
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA