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The map label for this gene is 209548020

Identifier: 209548020

GI number: 209548020

Start: 423902

End: 424918

Strand: Direct

Name: 209548020

Synonym: Rleg2_0412

Alternate gene names: NA

Gene position: 423902-424918 (Clockwise)

Preceding gene: 209548019

Following gene: 209548021

Centisome position: 9.34

GC content: 56.74

Gene sequence:

>1017_bases
ATGTTCCGCAACTACCGGCCTGATCGCTGCTATATCATAGCCGAGATCGGCGGCAACTTTACGACGTTCGATCAGGCAAA
GCGCCTGATTGACGAGGCAAAGGCGTCAGGGGTGGATGCCGTCAAGCTCCAGACGTATCGTGCCGAAACATTATCGAGTC
GGAATGCCATGTTCGATATGGAGAACACCGGCGTTACCTCGCAATTCGAGCTTTTCCGTAAATATGAAATCGGTCACGAG
CTTCACGAAGCGGTTTTCCGCTATGCCGAGGAGCAAGCCCTGGACTGGTTTTCGTCTCCCTCACATGAGACGGATGTCGA
CCTGCTGGAGAGATGTGGCGTTGGCGCCCACAAGGTTGGGTCTGACGACGCGGTCAACATTCCTTTTCTTCGGTATCTGG
CAAGAACGGGCAAGCCGATAATCTTGTCGACCGGGATGTCGACGCTCGAAGAGGTTCGGGAATCCGTCGCCGCAATCAAG
GACGCGGGCAACGACAAGCTCATCCTGCTGCACGCCATCACAAGCTATCCGACGCATCCGGAAAATGTGAACCTAGGTGC
GATGCAAACGATGATGGAGGTGTTTCCGGATCTCGATGTTGGCTATTCCGACCATACATTGAACCCTGTCGCGAGCCTTT
GCGCGGTCGCGATGGGCGCCCGGGTCATCGAGCGGCATTTCACCTACGACAAGGCCGCCGACGGTCCAGATCACATGCTT
TCGGCTGATCCAGCGGAAATGAAATGGCTTGTGGATGCGATACGCGCGTTCGAGATCATGAAAGGCAGCGGTCGCAAAGA
GCCGGCTGCAAGTGAGGCGACGACCAGATTGAACAACCGCAAGAGCGTCGTTCTCAATCGACCGCTCAAAGCCGGTGACG
TCATTTCCGCCGGCGACATTTCGGTTAAGCGGCCGGGGACGGGAATCGAGCCTAAGCATCTGGAAACTCTCGCCGGGCGA
AGACTGCTAAGAGACCTCGAAGGCGACGCCGTCCTCCAGTGGAGCGATCTGGCGTGA

Upstream 100 bases:

>100_bases
GGCGATAATCGACCGCAATGTGCGCACCCCAAGATTGGGCTTGGCCATGCCACCAGGGCGCAAGGCAACTTTGCCGGTCG
TGAATTACAGGGAGTGACGA

Downstream 100 bases:

>100_bases
CGCTTGGAATCATCATCCAGGCGCGGATGGGATCGACGCGGCTGCCGGGAAAAGTCCTTCGCGACATTTCCGGCAAGCCC
CTTCTCGCACATGTCCTTGG

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MFRNYRPDRCYIIAEIGGNFTTFDQAKRLIDEAKASGVDAVKLQTYRAETLSSRNAMFDMENTGVTSQFELFRKYEIGHE
LHEAVFRYAEEQALDWFSSPSHETDVDLLERCGVGAHKVGSDDAVNIPFLRYLARTGKPIILSTGMSTLEEVRESVAAIK
DAGNDKLILLHAITSYPTHPENVNLGAMQTMMEVFPDLDVGYSDHTLNPVASLCAVAMGARVIERHFTYDKAADGPDHML
SADPAEMKWLVDAIRAFEIMKGSGRKEPAASEATTRLNNRKSVVLNRPLKAGDVISAGDISVKRPGTGIEPKHLETLAGR
RLLRDLEGDAVLQWSDLA

Sequences:

>Translated_338_residues
MFRNYRPDRCYIIAEIGGNFTTFDQAKRLIDEAKASGVDAVKLQTYRAETLSSRNAMFDMENTGVTSQFELFRKYEIGHE
LHEAVFRYAEEQALDWFSSPSHETDVDLLERCGVGAHKVGSDDAVNIPFLRYLARTGKPIILSTGMSTLEEVRESVAAIK
DAGNDKLILLHAITSYPTHPENVNLGAMQTMMEVFPDLDVGYSDHTLNPVASLCAVAMGARVIERHFTYDKAADGPDHML
SADPAEMKWLVDAIRAFEIMKGSGRKEPAASEATTRLNNRKSVVLNRPLKAGDVISAGDISVKRPGTGIEPKHLETLAGR
RLLRDLEGDAVLQWSDLA
>Mature_338_residues
MFRNYRPDRCYIIAEIGGNFTTFDQAKRLIDEAKASGVDAVKLQTYRAETLSSRNAMFDMENTGVTSQFELFRKYEIGHE
LHEAVFRYAEEQALDWFSSPSHETDVDLLERCGVGAHKVGSDDAVNIPFLRYLARTGKPIILSTGMSTLEEVRESVAAIK
DAGNDKLILLHAITSYPTHPENVNLGAMQTMMEVFPDLDVGYSDHTLNPVASLCAVAMGARVIERHFTYDKAADGPDHML
SADPAEMKWLVDAIRAFEIMKGSGRKEPAASEATTRLNNRKSVVLNRPLKAGDVISAGDISVKRPGTGIEPKHLETLAGR
RLLRDLEGDAVLQWSDLA

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=326, Percent_Identity=33.4355828220859, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21357081, Length=350, Percent_Identity=30, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 37415; Mature: 37415

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRNYRPDRCYIIAEIGGNFTTFDQAKRLIDEAKASGVDAVKLQTYRAETLSSRNAMFDM
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEC
ENTGVTSQFELFRKYEIGHELHEAVFRYAEEQALDWFSSPSHETDVDLLERCGVGAHKVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCC
SDDAVNIPFLRYLARTGKPIILSTGMSTLEEVRESVAAIKDAGNDKLILLHAITSYPTHP
CCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
ENVNLGAMQTMMEVFPDLDVGYSDHTLNPVASLCAVAMGARVIERHFTYDKAADGPDHML
CCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCC
SADPAEMKWLVDAIRAFEIMKGSGRKEPAASEATTRLNNRKSVVLNRPLKAGDVISAGDI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEECCCE
SVKRPGTGIEPKHLETLAGRRLLRDLEGDAVLQWSDLA
EEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MFRNYRPDRCYIIAEIGGNFTTFDQAKRLIDEAKASGVDAVKLQTYRAETLSSRNAMFDM
CCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCEEEC
ENTGVTSQFELFRKYEIGHELHEAVFRYAEEQALDWFSSPSHETDVDLLERCGVGAHKVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCC
SDDAVNIPFLRYLARTGKPIILSTGMSTLEEVRESVAAIKDAGNDKLILLHAITSYPTHP
CCCCCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCC
ENVNLGAMQTMMEVFPDLDVGYSDHTLNPVASLCAVAMGARVIERHFTYDKAADGPDHML
CCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCC
SADPAEMKWLVDAIRAFEIMKGSGRKEPAASEATTRLNNRKSVVLNRPLKAGDVISAGDI
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCEEECCCE
SVKRPGTGIEPKHLETLAGRRLLRDLEGDAVLQWSDLA
EEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]