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The map label for this gene is tsr [C]

Identifier: 209547977

GI number: 209547977

Start: 376979

End: 378826

Strand: Direct

Name: tsr [C]

Synonym: Rleg2_0369

Alternate gene names: 209547977

Gene position: 376979-378826 (Clockwise)

Preceding gene: 209547976

Following gene: 209547979

Centisome position: 8.31

GC content: 64.12

Gene sequence:

>1848_bases
ATGCTGCGCCTTTTTTCTACGTCGATCGTCCGCCAGATCGTTGCCATCACGCTCTGTCTGCTAGCCGTCAGCACCGCCGC
CATCGTCGGCGCGACCTATTATAATCTCAGCCGTTATGTCATGGACGGGGCCGTCTCCGACGCCAGGGATGCCACCCGCG
CCATGGCCGTCCTCTATGGCGCGGCCGATCAGGCGGCAAAGATCGAGCTGAAAGACGATGGGCTTTCCACCGTCACGGAA
GACGCCATCCCGGCCCTTGCCGATCATTCGCTGGTCGACCGCACGGCGCAGTCGATCGCCGGTGTTGCCACAATCTTCCA
GAAGCAGGGCGGCGACTACGTCCGCATCTCCACCAACGTCAAGAAGGAAAACGGCGACCGTGCCGTCGGCACCAAGCTGG
TCGCCGAGCATCCCGCTCAGCCGGTTCTCGCCAGGGGCGACGCCTATTACGGCCAGGCCGAGCTTTTCGGCCGCAAGTTC
ATGACCGGTTATTTCCCGGTCAAGAACGCATCGAATGCCAATGTCGGCATTCTCTTCATCGGCATTCCGATGGAAGTCTA
TTATCAGCGCATGTATAAGCTGCAGATGCTGGTCCTCGGCGTCGGCGCCATCGTCATGCTCATCGTCGGCGTTCTCGCCT
TCTATGCGATCCGCCTGTCGGTGAAGCCTTTGCAGGCGCTGACCGCGAGCGTTCACGCGATCTCCTCGGGCGATCTCGAC
GGCGCGATCCCCTGCGTCGAGAAGAAGAACGAGTTCGGCGATATCGGCCGGGCTTTGGCGCTGTTCCGCGATAGCGCCCG
CGCCAGGCGCGATCTGGAAACCCAGGCAGCCGAACAGCGCGCCTTGAGCGATGCCGAACGCGCCAGGAACGATGCCGACA
AGCGCTCGCTCGACAGCCAGATCGACTTTGCCGTCAACGAGCTTGCCGCCGGCCTCGGACGCCTGTCGCAGGGCGATGTC
TCCGAAACGATCGGCACACCCTTCGTCGGCCGGCTGGAGCAGCTGCGTGTCGATTTCAATGCTTCGCTGCTGCGGCTCCA
GGATACGCTCTCCGGTATCCGTGACAGCGCCTCGACCATCCAGCGCAACAGCGGCGCCGTCTCGGTTTCAGCAAGTGAGC
TTTCGAAGCGCACCGAGGCGCAGGCGGCAAGTCTAGAAGAGACCGCCGCCGCGGTTGAGGAGATTACCGTCACGGTTCGC
TCCTCCGCCGAGCGCGCCCGCGAAGCCAACAGCGTCGTGGCCGCGACCAAGAAGACGGCCGACAATTCCGGCGCCGTCGT
CGGCGATGCCGTCGCCGCCATGGAGCGCATCGAAGAGGCCTCGCAACGCATCGAGCAGATCATCGAGGTGATCGACGATA
TCGCCTTCCAGACCAACCTGCTGGCGCTCAACGCCGGCATCGAGGCGGCCCGCGCCGGCGAGGCAGGCAAGGGTTTTGCC
GTCGTCGCCCAGGAGGTCCGCGAACTCGCCCAGCGTTCGGCCGATGCGGCGCGTGAGATCAAGTCGCTGATCGAGACCTC
CAGCCGCGAGGTGACGGTGGGCTCCGAACTTGTTCAGAAGACCGGCAGCGTCCTTGCGGCGATCAGCCATGAGATCATCG
CGATCAGCGGCCATGTCGAGACCATCGCCACCGCAAGCCGCGATCAGTCGGCAGCACTGCAGGAGGTCAACGGTTCGGTG
AACGCCATGGACCAGATGACCCAGAAGAACGCCTCGATGGTGGCCGAGACCACGCAGGCAAGCCGCCTGCTTGCCGGCGA
GGCCGATACGCTGATGGCGCTGATCGAGCGCTTCCGGATCATTGCCGAGCCCGCCGCCGCTCACCTTGGGACCAGGAAGG
TCGCCTGA

Upstream 100 bases:

>100_bases
TTATGTTTTAGAATCGCGCTGCCTGCGGCCCTGATCTACCGAAAATTTTCCTTAACGCTTTTCGTCTAATTTAGCCTCGA
TTTGTCTGCCGGGGGTTTTG

Downstream 100 bases:

>100_bases
GGCGCGCAGCCGCAACTGCCGGATCGCACCGCAGCTTTGCGGCGTCGTCTGAGACTGAGATCGAGCGAGGTCAGCCAGGC
GGCGAAATTGACGAGACCGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MLRLFSTSIVRQIVAITLCLLAVSTAAIVGATYYNLSRYVMDGAVSDARDATRAMAVLYGAADQAAKIELKDDGLSTVTE
DAIPALADHSLVDRTAQSIAGVATIFQKQGGDYVRISTNVKKENGDRAVGTKLVAEHPAQPVLARGDAYYGQAELFGRKF
MTGYFPVKNASNANVGILFIGIPMEVYYQRMYKLQMLVLGVGAIVMLIVGVLAFYAIRLSVKPLQALTASVHAISSGDLD
GAIPCVEKKNEFGDIGRALALFRDSARARRDLETQAAEQRALSDAERARNDADKRSLDSQIDFAVNELAAGLGRLSQGDV
SETIGTPFVGRLEQLRVDFNASLLRLQDTLSGIRDSASTIQRNSGAVSVSASELSKRTEAQAASLEETAAAVEEITVTVR
SSAERAREANSVVAATKKTADNSGAVVGDAVAAMERIEEASQRIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
VVAQEVRELAQRSADAAREIKSLIETSSREVTVGSELVQKTGSVLAAISHEIIAISGHVETIATASRDQSAALQEVNGSV
NAMDQMTQKNASMVAETTQASRLLAGEADTLMALIERFRIIAEPAAAHLGTRKVA

Sequences:

>Translated_615_residues
MLRLFSTSIVRQIVAITLCLLAVSTAAIVGATYYNLSRYVMDGAVSDARDATRAMAVLYGAADQAAKIELKDDGLSTVTE
DAIPALADHSLVDRTAQSIAGVATIFQKQGGDYVRISTNVKKENGDRAVGTKLVAEHPAQPVLARGDAYYGQAELFGRKF
MTGYFPVKNASNANVGILFIGIPMEVYYQRMYKLQMLVLGVGAIVMLIVGVLAFYAIRLSVKPLQALTASVHAISSGDLD
GAIPCVEKKNEFGDIGRALALFRDSARARRDLETQAAEQRALSDAERARNDADKRSLDSQIDFAVNELAAGLGRLSQGDV
SETIGTPFVGRLEQLRVDFNASLLRLQDTLSGIRDSASTIQRNSGAVSVSASELSKRTEAQAASLEETAAAVEEITVTVR
SSAERAREANSVVAATKKTADNSGAVVGDAVAAMERIEEASQRIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
VVAQEVRELAQRSADAAREIKSLIETSSREVTVGSELVQKTGSVLAAISHEIIAISGHVETIATASRDQSAALQEVNGSV
NAMDQMTQKNASMVAETTQASRLLAGEADTLMALIERFRIIAEPAAAHLGTRKVA
>Mature_615_residues
MLRLFSTSIVRQIVAITLCLLAVSTAAIVGATYYNLSRYVMDGAVSDARDATRAMAVLYGAADQAAKIELKDDGLSTVTE
DAIPALADHSLVDRTAQSIAGVATIFQKQGGDYVRISTNVKKENGDRAVGTKLVAEHPAQPVLARGDAYYGQAELFGRKF
MTGYFPVKNASNANVGILFIGIPMEVYYQRMYKLQMLVLGVGAIVMLIVGVLAFYAIRLSVKPLQALTASVHAISSGDLD
GAIPCVEKKNEFGDIGRALALFRDSARARRDLETQAAEQRALSDAERARNDADKRSLDSQIDFAVNELAAGLGRLSQGDV
SETIGTPFVGRLEQLRVDFNASLLRLQDTLSGIRDSASTIQRNSGAVSVSASELSKRTEAQAASLEETAAAVEEITVTVR
SSAERAREANSVVAATKKTADNSGAVVGDAVAAMERIEEASQRIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
VVAQEVRELAQRSADAAREIKSLIETSSREVTVGSELVQKTGSVLAAISHEIIAISGHVETIATASRDQSAALQEVNGSV
NAMDQMTQKNASMVAETTQASRLLAGEADTLMALIERFRIIAEPAAAHLGTRKVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=270, Percent_Identity=45.9259259259259, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1788195, Length=259, Percent_Identity=44.4015444015444, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1788194, Length=263, Percent_Identity=42.9657794676806, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1787690, Length=302, Percent_Identity=38.7417218543046, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1789453, Length=242, Percent_Identity=33.4710743801653, Blast_Score=138, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 65321; Mature: 65321

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLFSTSIVRQIVAITLCLLAVSTAAIVGATYYNLSRYVMDGAVSDARDATRAMAVLYG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
AADQAAKIELKDDGLSTVTEDAIPALADHSLVDRTAQSIAGVATIFQKQGGDYVRISTNV
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KKENGDRAVGTKLVAEHPAQPVLARGDAYYGQAELFGRKFMTGYFPVKNASNANVGILFI
CCCCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GIPMEVYYQRMYKLQMLVLGVGAIVMLIVGVLAFYAIRLSVKPLQALTASVHAISSGDLD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
GAIPCVEKKNEFGDIGRALALFRDSARARRDLETQAAEQRALSDAERARNDADKRSLDSQ
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IDFAVNELAAGLGRLSQGDVSETIGTPFVGRLEQLRVDFNASLLRLQDTLSGIRDSASTI
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QRNSGAVSVSASELSKRTEAQAASLEETAAAVEEITVTVRSSAERAREANSVVAATKKTA
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DNSGAVVGDAVAAMERIEEASQRIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCCHH
VVAQEVRELAQRSADAAREIKSLIETSSREVTVGSELVQKTGSVLAAISHEIIAISGHVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEECCHH
TIATASRDQSAALQEVNGSVNAMDQMTQKNASMVAETTQASRLLAGEADTLMALIERFRI
HHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IAEPAAAHLGTRKVA
HHCHHHHHCCCCCCC
>Mature Secondary Structure
MLRLFSTSIVRQIVAITLCLLAVSTAAIVGATYYNLSRYVMDGAVSDARDATRAMAVLYG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
AADQAAKIELKDDGLSTVTEDAIPALADHSLVDRTAQSIAGVATIFQKQGGDYVRISTNV
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
KKENGDRAVGTKLVAEHPAQPVLARGDAYYGQAELFGRKFMTGYFPVKNASNANVGILFI
CCCCCCHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
GIPMEVYYQRMYKLQMLVLGVGAIVMLIVGVLAFYAIRLSVKPLQALTASVHAISSGDLD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
GAIPCVEKKNEFGDIGRALALFRDSARARRDLETQAAEQRALSDAERARNDADKRSLDSQ
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IDFAVNELAAGLGRLSQGDVSETIGTPFVGRLEQLRVDFNASLLRLQDTLSGIRDSASTI
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QRNSGAVSVSASELSKRTEAQAASLEETAAAVEEITVTVRSSAERAREANSVVAATKKTA
HCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DNSGAVVGDAVAAMERIEEASQRIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCCHH
VVAQEVRELAQRSADAAREIKSLIETSSREVTVGSELVQKTGSVLAAISHEIIAISGHVE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEECCHH
TIATASRDQSAALQEVNGSVNAMDQMTQKNASMVAETTQASRLLAGEADTLMALIERFRI
HHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IAEPAAAHLGTRKVA
HHCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]