| Definition | Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, complete genome. |
|---|---|
| Accession | NC_011369 |
| Length | 4,537,948 |
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The map label for this gene is gno [H]
Identifier: 209547873
GI number: 209547873
Start: 269380
End: 270153
Strand: Direct
Name: gno [H]
Synonym: Rleg2_0264
Alternate gene names: 209547873
Gene position: 269380-270153 (Clockwise)
Preceding gene: 209547872
Following gene: 209547874
Centisome position: 5.94
GC content: 66.41
Gene sequence:
>774_bases ATGAGCTACCAGAAGAAATTTCGCCTCGACGGCGAACGTGCTGTGGTCACCGGCGGAGGGCGCGCGATCGGGCTCTGCTG CACCGAGGCGCTGGCGGAGGCGGGTGCGGCTGTCGTCGTCATCGAACGCAGCGAGGCCGACGCCCGGCAAGCGCTTGCAC TGCGCGACAAGGGCTACGACATCGACGTCCGGGTGGGCGACGTTACCGACGCCGGCCGGATGGACGCAATCGCCAATGAG CTTGCCGACGGAGGCCGGCCGGCGACGATCCTGGTGAACAATGCCGGGATTGGCCAGAGCGGCATCCCGGCAGAAGATCT CACCGACGCGGACTGGCTGCGCATGATGGACGTCAATCTCAACGGCGTCTTCTGGTGCTCGCGCGCCTTCGGCCGACACA TGGTCTCGATGAAGCGGGGCGCCATCGTCAACCTCGGCTCGATGTCGGGGCACATCTGCAACCGGCCGCAGCCCCAGACG GCCTATAATGTCTCCAAGGCGGCAGTCCATCACCTCACGCGGTCGCTGGCCGCCGAATGGGCGCAGCATGGTATCCGGGT GAACGCCGTCGCGCCCACCTACATCGAGACGCCGATGGTGGTGGCCGTCGAAGCCAATCGCGAGCGCATTCCGCTCTGGC TGGCCGACACGCCGATGGGCCGGATGGGAACGCCGGAGGAGGTAGCAAGCGCGGTCCTCTTTCTGGCAACGGGCGCAGCC AGCCTGATGACCGGAGCAATCGTCAACGTCGATGCGGGATTCACCTGCTGGTAG
Upstream 100 bases:
>100_bases TCGCCGACGCGATCATCTTCATGCTGACCCGGCCGCGCAACGTCACTATCCGCGATATCGTCGTCCTTCCAAGCGCATTC GACATCTGAAGGAGCCTGAT
Downstream 100 bases:
>100_bases CCCTTTCGGGACGAGGCGCGAGCGGCGCCTCGTCCGCATTATAAGAGTGCCTGCCGGGAAAAGTCAGCGATATGGAAACG TTACCACATCGTCTTGACTC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 257; Mature: 256
Protein sequence:
>257_residues MSYQKKFRLDGERAVVTGGGRAIGLCCTEALAEAGAAVVVIERSEADARQALALRDKGYDIDVRVGDVTDAGRMDAIANE LADGGRPATILVNNAGIGQSGIPAEDLTDADWLRMMDVNLNGVFWCSRAFGRHMVSMKRGAIVNLGSMSGHICNRPQPQT AYNVSKAAVHHLTRSLAAEWAQHGIRVNAVAPTYIETPMVVAVEANRERIPLWLADTPMGRMGTPEEVASAVLFLATGAA SLMTGAIVNVDAGFTCW
Sequences:
>Translated_257_residues MSYQKKFRLDGERAVVTGGGRAIGLCCTEALAEAGAAVVVIERSEADARQALALRDKGYDIDVRVGDVTDAGRMDAIANE LADGGRPATILVNNAGIGQSGIPAEDLTDADWLRMMDVNLNGVFWCSRAFGRHMVSMKRGAIVNLGSMSGHICNRPQPQT AYNVSKAAVHHLTRSLAAEWAQHGIRVNAVAPTYIETPMVVAVEANRERIPLWLADTPMGRMGTPEEVASAVLFLATGAA SLMTGAIVNVDAGFTCW >Mature_256_residues SYQKKFRLDGERAVVTGGGRAIGLCCTEALAEAGAAVVVIERSEADARQALALRDKGYDIDVRVGDVTDAGRMDAIANEL ADGGRPATILVNNAGIGQSGIPAEDLTDADWLRMMDVNLNGVFWCSRAFGRHMVSMKRGAIVNLGSMSGHICNRPQPQTA YNVSKAAVHHLTRSLAAEWAQHGIRVNAVAPTYIETPMVVAVEANRERIPLWLADTPMGRMGTPEEVASAVLFLATGAAS LMTGAIVNVDAGFTCW
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=32.962962962963, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI19923817, Length=271, Percent_Identity=32.4723247232472, Blast_Score=108, Evalue=6e-24, Organism=Homo sapiens, GI66933014, Length=261, Percent_Identity=30.6513409961686, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI7705925, Length=252, Percent_Identity=31.7460317460317, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=32.2175732217573, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=32, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI10190704, Length=269, Percent_Identity=31.5985130111524, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=29.6, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503301, Length=231, Percent_Identity=27.7056277056277, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI20149619, Length=230, Percent_Identity=31.7391304347826, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=29.8039215686275, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503817, Length=238, Percent_Identity=28.1512605042017, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI226371731, Length=213, Percent_Identity=30.0469483568075, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI59889578, Length=238, Percent_Identity=27.7310924369748, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI7705855, Length=196, Percent_Identity=31.6326530612245, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=27.1844660194175, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=32.9317269076305, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=34.251968503937, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=34.9397590361446, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=30.6451612903226, Blast_Score=117, Evalue=7e-28, Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=33.203125, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=31.6602316602317, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=34.1085271317829, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=30.241935483871, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=29.9212598425197, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=27.1653543307087, Blast_Score=74, Evalue=8e-15, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=35.9683794466403, Blast_Score=124, Evalue=4e-29, Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=34.251968503937, Blast_Score=113, Evalue=8e-26, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=29.2, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=32.8125, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=29.9212598425197, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17536025, Length=265, Percent_Identity=31.3207547169811, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=31.1538461538462, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17561272, Length=222, Percent_Identity=32.4324324324324, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=30.188679245283, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=31.4606741573034, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17559104, Length=268, Percent_Identity=30.5970149253731, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI71994600, Length=170, Percent_Identity=35.8823529411765, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=30.5660377358491, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17562904, Length=251, Percent_Identity=30.6772908366534, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI193204405, Length=265, Percent_Identity=30.5660377358491, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI72000259, Length=244, Percent_Identity=27.8688524590164, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI71994604, Length=167, Percent_Identity=34.7305389221557, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=26.1194029850746, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=28.030303030303, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560220, Length=247, Percent_Identity=29.9595141700405, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562906, Length=278, Percent_Identity=29.4964028776978, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17563726, Length=244, Percent_Identity=27.0491803278689, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538480, Length=250, Percent_Identity=29.2, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.2388059701493, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17562908, Length=276, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17538486, Length=243, Percent_Identity=27.1604938271605, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17551412, Length=251, Percent_Identity=29.8804780876494, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=27.9245283018868, Blast_Score=68, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=249, Percent_Identity=28.9156626506024, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=25.8964143426295, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=32.0158102766798, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=37.007874015748, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=31.3253012048193, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI24644337, Length=235, Percent_Identity=31.063829787234, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=31.5175097276265, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=33.0645161290323, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=32.8, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.4, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24640442, Length=202, Percent_Identity=34.6534653465347, Blast_Score=80, Evalue=9e-16, Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=32.9896907216495, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=32.9896907216495, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI161076933, Length=193, Percent_Identity=32.1243523316062, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24584748, Length=193, Percent_Identity=32.1243523316062, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI21356301, Length=239, Percent_Identity=28.4518828451883, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=28.515625, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI281364494, Length=241, Percent_Identity=27.8008298755187, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27353; Mature: 27221
Theoretical pI: Translated: 6.02; Mature: 6.02
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 4.3 %Met (Translated Protein) 6.2 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 5.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSYQKKFRLDGERAVVTGGGRAIGLCCTEALAEAGAAVVVIERSEADARQALALRDKGYD CCCCCCEECCCCEEEEECCCCEEHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCE IDVRVGDVTDAGRMDAIANELADGGRPATILVNNAGIGQSGIPAEDLTDADWLRMMDVNL EEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECC NGVFWCSRAFGRHMVSMKRGAIVNLGSMSGHICNRPQPQTAYNVSKAAVHHLTRSLAAEW CEEEEEHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH AQHGIRVNAVAPTYIETPMVVAVEANRERIPLWLADTPMGRMGTPEEVASAVLFLATGAA HHCCEEEEEECCCEECCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCHH SLMTGAIVNVDAGFTCW HHHHCEEEEECCCCCCC >Mature Secondary Structure SYQKKFRLDGERAVVTGGGRAIGLCCTEALAEAGAAVVVIERSEADARQALALRDKGYD CCCCCEECCCCEEEEECCCCEEHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCE IDVRVGDVTDAGRMDAIANELADGGRPATILVNNAGIGQSGIPAEDLTDADWLRMMDVNL EEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECC NGVFWCSRAFGRHMVSMKRGAIVNLGSMSGHICNRPQPQTAYNVSKAAVHHLTRSLAAEW CEEEEEHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH AQHGIRVNAVAPTYIETPMVVAVEANRERIPLWLADTPMGRMGTPEEVASAVLFLATGAA HHCCEEEEEECCCEECCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCHH SLMTGAIVNVDAGFTCW HHHHCEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]