| Definition | Rhizobium leguminosarum bv. trifolii WSM2304 chromosome, complete genome. |
|---|---|
| Accession | NC_011369 |
| Length | 4,537,948 |
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The map label for this gene is rbtD [H]
Identifier: 209547872
GI number: 209547872
Start: 268643
End: 269368
Strand: Direct
Name: rbtD [H]
Synonym: Rleg2_0263
Alternate gene names: 209547872
Gene position: 268643-269368 (Clockwise)
Preceding gene: 209547871
Following gene: 209547873
Centisome position: 5.92
GC content: 60.88
Gene sequence:
>726_bases ATGACAGAATTGGATGGGAAGATCGCGGCGGTCACGGGTGCGGCGTCCGGCATAGGATTGGCCTCGACGGAGGCAATGCT CGCCGCGGGCGCGAGGGTCGTGCTGGTGGACCGGGATGAGAAGGCCCTTGAGGCGGTTTGCAGCCGGCTTGGCGAGCGCG CTATTCCGCTCGTGATCAACCTGCTCAATCCGAACGAGTGCGCGGGACTGCTTGAGGGCGTCCTGGCGAAGACGGGCAAA CTCGACATCCTGCATGCCAATGCCGGCACCTATATCGGCGGCGACCTTGTGGAAACCGACCTCGAAACGATCGATCGGAT GCTCAATCTCAATGTGAATGTCGTCATCAAGAACGTTCACAATGTCATTCCGCACATGATCGAACGCGGCACCGGCGACA TTGTCGTCACGAGCTCGGTCGCTGGACATTCGGCTATCCCGTGGGAGCCGGTGTATTCCTCGTCGAAATGGGCGATGACC TGCTTCGTCCAGACGATGCGGCGCCAGCTTCTGAAAAACGGCATTCGCGTGGGGTCGGTATCGCCGGGGCCGGTGATCAG CGCTCTGCTTGCGGATTGGCCGGAGGAAAACCTTCGCAAGGCCAAGGAGGCCGGCGCGTTGATCGAGCCCAAGGAAGTCG CCGACGCGATCATCTTCATGCTGACCCGGCCGCGCAACGTCACTATCCGCGATATCGTCGTCCTTCCAAGCGCATTCGAC ATCTGA
Upstream 100 bases:
>100_bases GGTTCTGATCTGGAGAGTGACGAAGAGTCTGGCGGACTATCACGCCGCCTGCGGCGTCGGGAAGAATGAGCAATCAAAAT CAGGATAGGAGGAGACATCG
Downstream 100 bases:
>100_bases AGGAGCCTGATATGAGCTACCAGAAGAAATTTCGCCTCGACGGCGAACGTGCTGTGGTCACCGGCGGAGGGCGCGCGATC GGGCTCTGCTGCACCGAGGC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: RDH [H]
Number of amino acids: Translated: 241; Mature: 240
Protein sequence:
>241_residues MTELDGKIAAVTGAASGIGLASTEAMLAAGARVVLVDRDEKALEAVCSRLGERAIPLVINLLNPNECAGLLEGVLAKTGK LDILHANAGTYIGGDLVETDLETIDRMLNLNVNVVIKNVHNVIPHMIERGTGDIVVTSSVAGHSAIPWEPVYSSSKWAMT CFVQTMRRQLLKNGIRVGSVSPGPVISALLADWPEENLRKAKEAGALIEPKEVADAIIFMLTRPRNVTIRDIVVLPSAFD I
Sequences:
>Translated_241_residues MTELDGKIAAVTGAASGIGLASTEAMLAAGARVVLVDRDEKALEAVCSRLGERAIPLVINLLNPNECAGLLEGVLAKTGK LDILHANAGTYIGGDLVETDLETIDRMLNLNVNVVIKNVHNVIPHMIERGTGDIVVTSSVAGHSAIPWEPVYSSSKWAMT CFVQTMRRQLLKNGIRVGSVSPGPVISALLADWPEENLRKAKEAGALIEPKEVADAIIFMLTRPRNVTIRDIVVLPSAFD I >Mature_240_residues TELDGKIAAVTGAASGIGLASTEAMLAAGARVVLVDRDEKALEAVCSRLGERAIPLVINLLNPNECAGLLEGVLAKTGKL DILHANAGTYIGGDLVETDLETIDRMLNLNVNVVIKNVHNVIPHMIERGTGDIVVTSSVAGHSAIPWEPVYSSSKWAMTC FVQTMRRQLLKNGIRVGSVSPGPVISALLADWPEENLRKAKEAGALIEPKEVADAIIFMLTRPRNVTIRDIVVLPSAFDI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG4221
COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=218, Percent_Identity=27.9816513761468, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=28.1632653061224, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI210032110, Length=200, Percent_Identity=31, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI20149619, Length=249, Percent_Identity=27.3092369477912, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI31542939, Length=228, Percent_Identity=29.3859649122807, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI142976729, Length=239, Percent_Identity=26.7782426778243, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=29.9180327868852, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI7706318, Length=200, Percent_Identity=32.5, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=26.5560165975104, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI157739938, Length=238, Percent_Identity=26.0504201680672, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI7657478, Length=187, Percent_Identity=30.4812834224599, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI7705855, Length=192, Percent_Identity=30.2083333333333, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI32455239, Length=170, Percent_Identity=30, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI5031765, Length=170, Percent_Identity=30, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI223718074, Length=125, Percent_Identity=30.4, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=29.8245614035088, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI4758504, Length=206, Percent_Identity=26.6990291262136, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=220, Percent_Identity=29.0909090909091, Blast_Score=91, Evalue=5e-20, Organism=Escherichia coli, GI87082100, Length=193, Percent_Identity=34.1968911917098, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1787820, Length=234, Percent_Identity=24.7863247863248, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787905, Length=228, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1786812, Length=249, Percent_Identity=25.3012048192771, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1789208, Length=183, Percent_Identity=28.9617486338798, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786701, Length=199, Percent_Identity=28.1407035175879, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789378, Length=192, Percent_Identity=27.0833333333333, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI87082160, Length=201, Percent_Identity=24.3781094527363, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI72000259, Length=250, Percent_Identity=32, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17563726, Length=251, Percent_Identity=30.2788844621514, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17559104, Length=254, Percent_Identity=32.2834645669291, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562906, Length=246, Percent_Identity=28.4552845528455, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI193204405, Length=246, Percent_Identity=29.6747967479675, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17560150, Length=244, Percent_Identity=29.5081967213115, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17560220, Length=247, Percent_Identity=26.7206477732794, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17544670, Length=247, Percent_Identity=27.9352226720648, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=247, Percent_Identity=31.1740890688259, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562990, Length=244, Percent_Identity=29.0983606557377, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562908, Length=246, Percent_Identity=28.0487804878049, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17531453, Length=246, Percent_Identity=28.4552845528455, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17560676, Length=230, Percent_Identity=29.1304347826087, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538486, Length=247, Percent_Identity=29.5546558704453, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17562910, Length=252, Percent_Identity=27.3809523809524, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71994604, Length=241, Percent_Identity=26.5560165975104, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17561402, Length=201, Percent_Identity=27.8606965174129, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI71994600, Length=237, Percent_Identity=26.1603375527426, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17538480, Length=247, Percent_Identity=27.9352226720648, Blast_Score=77, Evalue=9e-15, Organism=Caenorhabditis elegans, GI17551412, Length=244, Percent_Identity=28.2786885245902, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562904, Length=246, Percent_Identity=28.4552845528455, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17565030, Length=194, Percent_Identity=31.9587628865979, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193203117, Length=201, Percent_Identity=26.3681592039801, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193203115, Length=205, Percent_Identity=27.3170731707317, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538182, Length=209, Percent_Identity=27.7511961722488, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17570069, Length=172, Percent_Identity=27.3255813953488, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17555706, Length=233, Percent_Identity=26.1802575107296, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=247, Percent_Identity=27.1255060728745, Blast_Score=90, Evalue=4e-19, Organism=Drosophila melanogaster, GI21357041, Length=233, Percent_Identity=32.618025751073, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI281364494, Length=250, Percent_Identity=30, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=32.4742268041237, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI28571526, Length=241, Percent_Identity=30.7053941908714, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI23397609, Length=235, Percent_Identity=31.4893617021277, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI116007236, Length=244, Percent_Identity=27.4590163934426, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI24644339, Length=228, Percent_Identity=31.140350877193, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI21355319, Length=236, Percent_Identity=30.5084745762712, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24663911, Length=252, Percent_Identity=28.1746031746032, Blast_Score=85, Evalue=3e-17, Organism=Drosophila melanogaster, GI24641232, Length=250, Percent_Identity=25.2, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24580925, Length=203, Percent_Identity=27.0935960591133, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571387, Length=247, Percent_Identity=25.5060728744939, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24644337, Length=235, Percent_Identity=33.6170212765957, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24648944, Length=238, Percent_Identity=26.890756302521, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=27.3092369477912, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI24639444, Length=224, Percent_Identity=27.6785714285714, Blast_Score=70, Evalue=8e-13, Organism=Drosophila melanogaster, GI24648693, Length=251, Percent_Identity=26.2948207171315, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21355889, Length=251, Percent_Identity=26.2948207171315, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=28.4313725490196, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI116007238, Length=184, Percent_Identity=28.2608695652174, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI221331218, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24665243, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21356301, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=25.8620689655172, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.56 [H]
Molecular weight: Translated: 25707; Mature: 25576
Theoretical pI: Translated: 5.35; Mature: 5.35
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTELDGKIAAVTGAASGIGLASTEAMLAAGARVVLVDRDEKALEAVCSRLGERAIPLVIN CCCCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEE LLNPNECAGLLEGVLAKTGKLDILHANAGTYIGGDLVETDLETIDRMLNLNVNVVIKNVH ECCCHHHHHHHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHCCCCEEEEHHHH NVIPHMIERGTGDIVVTSSVAGHSAIPWEPVYSSSKWAMTCFVQTMRRQLLKNGIRVGSV HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCC SPGPVISALLADWPEENLRKAKEAGALIEPKEVADAIIFMLTRPRNVTIRDIVVLPSAFD CCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCEEEEEEECCCCCC I C >Mature Secondary Structure TELDGKIAAVTGAASGIGLASTEAMLAAGARVVLVDRDEKALEAVCSRLGERAIPLVIN CCCCCEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCEEEEEE LLNPNECAGLLEGVLAKTGKLDILHANAGTYIGGDLVETDLETIDRMLNLNVNVVIKNVH ECCCHHHHHHHHHHHHCCCCEEEEECCCCCEECCHHHHHHHHHHHHHHCCCCEEEEHHHH NVIPHMIERGTGDIVVTSSVAGHSAIPWEPVYSSSKWAMTCFVQTMRRQLLKNGIRVGSV HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEECCC SPGPVISALLADWPEENLRKAKEAGALIEPKEVADAIIFMLTRPRNVTIRDIVVLPSAFD CCCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCEEEEEEECCCCCC I C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 3904726; 2933028; 3891331 [H]