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The map label for this gene is prtE [H]

Identifier: 209547855

GI number: 209547855

Start: 248821

End: 250263

Strand: Reverse

Name: prtE [H]

Synonym: Rleg2_0246

Alternate gene names: 209547855

Gene position: 250263-248821 (Counterclockwise)

Preceding gene: 209547856

Following gene: 209547854

Centisome position: 5.51

GC content: 61.26

Gene sequence:

>1443_bases
ATGACCCTTGTTCCACTGGACGCGCCCCCGGCGAAATTTTCGAATTCGTCAAGGATGGGCCAGCGCTTCGCTCATCGATG
GACAGCGACAGCCAGGCAGACGGCCTATCCGCCGGTGATCGAACAGAAACAGCGCGGACCCGCCGCCCCTTCGCCCATGC
CGGTGCTCAGAGGCGTCGTTTGGACGGGCAACCTGCTGATCCTGGTCTTTGTCGTCGGATTGGGAATCTGGTCGGCTCTG
GCCCCGCTGCACAGCGCTGCGGTCGCATCTGGCGTTATCGAGCCGGAGACCAGCCGCAAGACCATCCAGCATCTGGAAGG
CGGAATTGTGCGGCGGATCCTCGTCAGGAACGGCGATACGGTAATGGCCGGGCAAATCGTGATCGAGCTCGACGACACGA
AGTCCCGCTCGGAACGCGACAGCATCCAAGGGCAGCTGTGGGACGCCGAAGGAAGCCGCGCCCGCCTGCTTGCGGAGCAG
ACGGGCGGCGACCATGTCGCCTATCCCGACGATCTCAGGGCAGCCATGGACAAATATCCTTCGGTCAGCGCGATTCTGAC
CGGGCAACAGAAAATCTTCGAGGCTCGCCGCCGGGTCATGCAGGCGGAAATTCAGATCGGCAATGAAAAAATCGCGCAGG
TGCGGCAGGAAATCGTCGGACTTGGCGCCCAGAAGGCGGCACTCGCCGACAGAGCCGCAATCTCGCAGGAAGAACTGGAA
CAGGTGACGATCCTCACTGCCAAGGGACTGGAGAGAAGGAGCAGGCTTCTCAACCTCGAGCGCGAAAAAGCAGATCTTGA
CGGCCAGCAGGGCCAAGTCGGGGCACAGATCGCGCGCGCCTACCAGGTGATCAGCGAGTCGCAGGTCGATCTCGCAAAGC
TCGAGAGCGACCGGTTGAGCGAAGTCGCCCAAGGCATGCGCGATACGGAAAGCCGGATCATGCAATTGCGCGAGCGCTTG
CGGGCGATCGACGACCAACTTTCGAGGACCGATATCCGGGCTCCCGAAGATGGTACAATCATGAACCTGCGCATCCACAC
ATCAGGCGGGGTGATCGGCGCAGGCGAACCGCTCGTCGATCTTCTGCCACGCTCCGATCGCCTGATCGTGTCTGCCCATG
TCAGACCGGAGGACATCAATCTTGTCCATGCGGGGCTGGAGGCACAGGTGCACCTTCTTCCATACAATCAGCGGCGCGTT
CCACTGCTGAAAGGTCGGGTCGAGTATGTGTCAGCCGACCGCCTCACCGATACGCAGAGCGGCCAGCCCTATTATGCCGC
GACAATCCGCGTAACGGACGAGCGGCTGGCGAAAATGCGTGATGTCGAACTGGTCGCGGGCATGCCCGCACAGACACTGA
TCGAAACCGGCAAAAGCAGCGTGGCCCTCTACGCTGTCAGACCGCTTCTCGACAGTTTCAACAGAGCATTTCGTGAGGAC
TGA

Upstream 100 bases:

>100_bases
TGCGCAACGGCACGGTGGCTGCCTTCGGCGACAGCGAGCGGATTTATGAAACCTATCTTCAACCACCGGCGCGAACGGGA
AGCTAGGGAGGGACGCTGCC

Downstream 100 bases:

>100_bases
AGCGGTGATGGGCAAGCGAAAATTTGACGACGACCAGATTACGGGCATTCTCAAGGAGCACCAGGCCGGCGTGACGGTGG
CGGATGTTTGCCACCGATAC

Product: type I secretion membrane fusion protein, HlyD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MTLVPLDAPPAKFSNSSRMGQRFAHRWTATARQTAYPPVIEQKQRGPAAPSPMPVLRGVVWTGNLLILVFVVGLGIWSAL
APLHSAAVASGVIEPETSRKTIQHLEGGIVRRILVRNGDTVMAGQIVIELDDTKSRSERDSIQGQLWDAEGSRARLLAEQ
TGGDHVAYPDDLRAAMDKYPSVSAILTGQQKIFEARRRVMQAEIQIGNEKIAQVRQEIVGLGAQKAALADRAAISQEELE
QVTILTAKGLERRSRLLNLEREKADLDGQQGQVGAQIARAYQVISESQVDLAKLESDRLSEVAQGMRDTESRIMQLRERL
RAIDDQLSRTDIRAPEDGTIMNLRIHTSGGVIGAGEPLVDLLPRSDRLIVSAHVRPEDINLVHAGLEAQVHLLPYNQRRV
PLLKGRVEYVSADRLTDTQSGQPYYAATIRVTDERLAKMRDVELVAGMPAQTLIETGKSSVALYAVRPLLDSFNRAFRED

Sequences:

>Translated_480_residues
MTLVPLDAPPAKFSNSSRMGQRFAHRWTATARQTAYPPVIEQKQRGPAAPSPMPVLRGVVWTGNLLILVFVVGLGIWSAL
APLHSAAVASGVIEPETSRKTIQHLEGGIVRRILVRNGDTVMAGQIVIELDDTKSRSERDSIQGQLWDAEGSRARLLAEQ
TGGDHVAYPDDLRAAMDKYPSVSAILTGQQKIFEARRRVMQAEIQIGNEKIAQVRQEIVGLGAQKAALADRAAISQEELE
QVTILTAKGLERRSRLLNLEREKADLDGQQGQVGAQIARAYQVISESQVDLAKLESDRLSEVAQGMRDTESRIMQLRERL
RAIDDQLSRTDIRAPEDGTIMNLRIHTSGGVIGAGEPLVDLLPRSDRLIVSAHVRPEDINLVHAGLEAQVHLLPYNQRRV
PLLKGRVEYVSADRLTDTQSGQPYYAATIRVTDERLAKMRDVELVAGMPAQTLIETGKSSVALYAVRPLLDSFNRAFRED
>Mature_479_residues
TLVPLDAPPAKFSNSSRMGQRFAHRWTATARQTAYPPVIEQKQRGPAAPSPMPVLRGVVWTGNLLILVFVVGLGIWSALA
PLHSAAVASGVIEPETSRKTIQHLEGGIVRRILVRNGDTVMAGQIVIELDDTKSRSERDSIQGQLWDAEGSRARLLAEQT
GGDHVAYPDDLRAAMDKYPSVSAILTGQQKIFEARRRVMQAEIQIGNEKIAQVRQEIVGLGAQKAALADRAAISQEELEQ
VTILTAKGLERRSRLLNLEREKADLDGQQGQVGAQIARAYQVISESQVDLAKLESDRLSEVAQGMRDTESRIMQLRERLR
AIDDQLSRTDIRAPEDGTIMNLRIHTSGGVIGAGEPLVDLLPRSDRLIVSAHVRPEDINLVHAGLEAQVHLLPYNQRRVP
LLKGRVEYVSADRLTDTQSGQPYYAATIRVTDERLAKMRDVELVAGMPAQTLIETGKSSVALYAVRPLLDSFNRAFRED

Specific function: Involved in the secretion of proteases A, B, C and G [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 52917; Mature: 52786

Theoretical pI: Translated: 7.96; Mature: 7.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVPLDAPPAKFSNSSRMGQRFAHRWTATARQTAYPPVIEQKQRGPAAPSPMPVLRGVV
CEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHH
WTGNLLILVFVVGLGIWSALAPLHSAAVASGVIEPETSRKTIQHLEGGIVRRILVRNGDT
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHCCCCE
VMAGQIVIELDDTKSRSERDSIQGQLWDAEGSRARLLAEQTGGDHVAYPDDLRAAMDKYP
EEEEEEEEEECCCCCCCHHHCCCCEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCC
SVSAILTGQQKIFEARRRVMQAEIQIGNEKIAQVRQEIVGLGAQKAALADRAAISQEELE
CEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
QVTILTAKGLERRSRLLNLEREKADLDGQQGQVGAQIARAYQVISESQVDLAKLESDRLS
HEEEHHHHCHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EVAQGMRDTESRIMQLRERLRAIDDQLSRTDIRAPEDGTIMNLRIHTSGGVIGAGEPLVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEECCCHHHH
LLPRSDRLIVSAHVRPEDINLVHAGLEAQVHLLPYNQRRVPLLKGRVEYVSADRLTDTQS
HCCCCCCEEEEEECCCCCCCEEEECCCEEEEEECCCCCCCCHHHCCHHEEECCCCCCCCC
GQPYYAATIRVTDERLAKMRDVELVAGMPAQTLIETGKSSVALYAVRPLLDSFNRAFRED
CCCEEEEEEEECHHHHHHHHCHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLVPLDAPPAKFSNSSRMGQRFAHRWTATARQTAYPPVIEQKQRGPAAPSPMPVLRGVV
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHH
WTGNLLILVFVVGLGIWSALAPLHSAAVASGVIEPETSRKTIQHLEGGIVRRILVRNGDT
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHCCCCE
VMAGQIVIELDDTKSRSERDSIQGQLWDAEGSRARLLAEQTGGDHVAYPDDLRAAMDKYP
EEEEEEEEEECCCCCCCHHHCCCCEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCC
SVSAILTGQQKIFEARRRVMQAEIQIGNEKIAQVRQEIVGLGAQKAALADRAAISQEELE
CEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHH
QVTILTAKGLERRSRLLNLEREKADLDGQQGQVGAQIARAYQVISESQVDLAKLESDRLS
HEEEHHHHCHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EVAQGMRDTESRIMQLRERLRAIDDQLSRTDIRAPEDGTIMNLRIHTSGGVIGAGEPLVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEECCCHHHH
LLPRSDRLIVSAHVRPEDINLVHAGLEAQVHLLPYNQRRVPLLKGRVEYVSADRLTDTQS
HCCCCCCEEEEEECCCCCCCEEEECCCEEEEEECCCCCCCCHHHCCHHEEECCCCCCCCC
GQPYYAATIRVTDERLAKMRDVELVAGMPAQTLIETGKSSVALYAVRPLLDSFNRAFRED
CCCEEEEEEEECHHHHHHHHCHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2184029 [H]