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The map label for this gene is mcpA [H]

Identifier: 209547830

GI number: 209547830

Start: 223415

End: 225772

Strand: Direct

Name: mcpA [H]

Synonym: Rleg2_0221

Alternate gene names: 209547830

Gene position: 223415-225772 (Clockwise)

Preceding gene: 209547829

Following gene: 209547832

Centisome position: 4.92

GC content: 62.64

Gene sequence:

>2358_bases
ATGCTTTTCAAGTCTACGACAAGTCGCAATCTTTTCTCTGTGGCGGCCTGCGGCGTCATTGCCGTTATTGTCGCTTCGGG
GGCCATTTTCTATCGGTCCTATACTGAAATTCGCAGCGGCAGCATCGAACAGATGCGCCAGATCGCGACATCAGAGGCGC
TGAAGGTCGAAAAGAATATCGGCGGCACCGTGCATATCGTGGACGGGCTGAACGCCGTGCTGACGACGATGAAGGAAATG
GGCGACACCGATCGTGCCAAGGCGGACAAGGTCCTGCACAACATGCTGCAAGCCAATCCCCCGGTCCTTGGGATTTGGAC
CGGATGGGAGCCCAATGCTTTCGACGGCAAGGACAAGGATTACGTCGGCAAGGAAGGACACGACACGACGGGGCGCTATG
TGCCCTATTGGGTGCGCAGTGGCGGCCAGATCACCCATACGGCTTTGACGGATTACACCGTCGCTGGCGCGGGCGACTAT
TATCAACTGCCGTTCACGCAGCGCAAAACCGTGATCATCGAACCTTATTCTTATGCGATCGATGGAAAAGACGTTTTGAT
GACCTCCGTCACTGAGCCGGTTGTGATCGACGGCAAAGCCGTCGGCGTTGCCGGCCTTGACCTTTCGCTTCAGGACACCG
CCAAGGCGCTGTCAGCCAGCCGACCGATGGGAGCGGGTTTTCTTGGCCTGGTCACCAGTGCCGGCAAGATCGTCAGTCAC
CCGGATGCAAGCCTCATCGGCAAAAGCCTGTCCGAGACGGGCGCGAAAACTGCGGATTGGGACCATCTCATCGCCAATCC
CGGTCTTGAGCGTGAAGTGACCGATGAGGACGGCAATGTCTCCCTGGCGATTGCCATCGCCGTCAAGCTTGCCGAGGGCT
CCAATTGGTATGCGGTCGTTTCGGTCCCGAAGGCAACACTCTTCGCACCGCTCTATGCGGTGGTGCGGGATGCCATCGTC
GCGACGAGCCTGGCGGCGGTGCTGCTGGGCCTTGCCGGGTGGCTGATCGCACGCCGGTTCGTCGGCCGGATTTCCGGCGT
CATCGCCGAAACTGCCGCGATTGCCGCGGGCAAACTCGATGTGACCCTCAAGGACGGCGAGGCGAAGGACGAAATCGGCG
ATCTCTCCCGCTCGCTGAAGGCGCTGTTGGAGAGCAACCGCGACAGGGCGCGTCTGGAAGCCGAGGCGGAAGAAAACCGC
GCGCTGCAGGAACGGGAGCGCGCCGAGCGCGCCCGGATCGACCAGGCTCAGGAAGCGGACGTCAAATTCGCCGTCGGTGA
ATTGGCGCTTGGCCTGGCCAAGCTTGCCGAAGGCGACATGACGAGCGCGCTCGAGCATCCTTTCGCGGCGACGCTTGACG
AGACCCGCATCAATTTCAACGAGTCGGTCGTCAAGCTGCGTTCGGCGCTGGTATCGTTCTCGCAAAATGCCGAGGTCATC
CAAAGCGGCACCGAGGAGATCCGTTCTGCGGCCGACGACCTGGCGCGCCGGACGGAACAACAGGCTGCCTCCGTCGAGCA
AACTGCCGCAGCGCTTGAGCAGATTACGACATCCGTCAAGGATTCGACGGCGCGTGCCGAAGAAGCCGGGTCGATGGTTG
TTCGCACGAAGGAAAATGCCGAACGGTCCGGCCAGATCGTGCAGCGGGCCGTCGAAGCGATGAACGACATCGAACAGTCC
TCCAAGTCGATCTCCAATATCATCGGCGTCATCGACGAGATCGCCTTTCAGACAAACCTGCTTGCGCTGAACGCCGGCGT
CGAGGCGGCGCGTGCCGGTGAAGCCGGCAAGGGCTTCGCGGTCGTCGCTCAGGAGGTCCGGGAGCTGGCGCAGCGCTCGG
CCGGCGCGGCCAAGGAGATCAAGGCGCTGATCAGCGCCTCAGGCGGCCAGGTGCGGCATGGCGTTGCCCTGGTGCGTGAG
ACCGGCGATGCCTTGGACGGGATTGTTGAGGAGGTGCAGCAGATCGACCGCAATGTCCACGCGATCGTTCAATCCGCGCG
CGAGCAGTCGACCGGCCTTCAGGAGATCAATACCGCCGTCAATCAGATGGATCAGGCGACGCAGAAGAACGCGGCGATGG
TCGAGGAGTCGAATGCGGCGGCCCACACGCTTGCGACCGAGGTCTCCGCCCTGTCCGGACGGTTGGGCCAGTTCCGCCTC
GATACGGGCACGGGCATGACGTCGGCGCTATCGCGCTCGAACGCGCCGCGTCCGCTCGCCGCTCCGAAAATCGTCTCGTC
GCATGCGACGATCCCGGTTCCCTCGCCGGCGCGTGCGTTGAAGAAGACGCTGGCGGCCGCGCTTGGCGGCGGTTCAAAGG
CGGCCGCTCCGGCCGACCACGGCTGGGAGGATTTCTGA

Upstream 100 bases:

>100_bases
TTGGGGGGCCTTCAGTTTCTGCTGGATGACGGTTGTTTAAACGCGCCGGCGAATTGGACTTGAGGCATGCGCCAGTACAG
CAGCGAAGGCGAGCGGGAAC

Downstream 100 bases:

>100_bases
GCCGATCCGTTCAACGGAACGGTGACGAATGCCCTCCATGGGTGATTACGGCGGCCGTCCTCAGGCCGCCGCTTTCCGCC
GTCCGGCGCGAAGCCCCAGC

Product: methyl-accepting chemotaxis sensory transducer with Cache sensor

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MLFKSTTSRNLFSVAACGVIAVIVASGAIFYRSYTEIRSGSIEQMRQIATSEALKVEKNIGGTVHIVDGLNAVLTTMKEM
GDTDRAKADKVLHNMLQANPPVLGIWTGWEPNAFDGKDKDYVGKEGHDTTGRYVPYWVRSGGQITHTALTDYTVAGAGDY
YQLPFTQRKTVIIEPYSYAIDGKDVLMTSVTEPVVIDGKAVGVAGLDLSLQDTAKALSASRPMGAGFLGLVTSAGKIVSH
PDASLIGKSLSETGAKTADWDHLIANPGLEREVTDEDGNVSLAIAIAVKLAEGSNWYAVVSVPKATLFAPLYAVVRDAIV
ATSLAAVLLGLAGWLIARRFVGRISGVIAETAAIAAGKLDVTLKDGEAKDEIGDLSRSLKALLESNRDRARLEAEAEENR
ALQERERAERARIDQAQEADVKFAVGELALGLAKLAEGDMTSALEHPFAATLDETRINFNESVVKLRSALVSFSQNAEVI
QSGTEEIRSAADDLARRTEQQAASVEQTAAALEQITTSVKDSTARAEEAGSMVVRTKENAERSGQIVQRAVEAMNDIEQS
SKSISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAGAAKEIKALISASGGQVRHGVALVRE
TGDALDGIVEEVQQIDRNVHAIVQSAREQSTGLQEINTAVNQMDQATQKNAAMVEESNAAAHTLATEVSALSGRLGQFRL
DTGTGMTSALSRSNAPRPLAAPKIVSSHATIPVPSPARALKKTLAAALGGGSKAAAPADHGWEDF

Sequences:

>Translated_785_residues
MLFKSTTSRNLFSVAACGVIAVIVASGAIFYRSYTEIRSGSIEQMRQIATSEALKVEKNIGGTVHIVDGLNAVLTTMKEM
GDTDRAKADKVLHNMLQANPPVLGIWTGWEPNAFDGKDKDYVGKEGHDTTGRYVPYWVRSGGQITHTALTDYTVAGAGDY
YQLPFTQRKTVIIEPYSYAIDGKDVLMTSVTEPVVIDGKAVGVAGLDLSLQDTAKALSASRPMGAGFLGLVTSAGKIVSH
PDASLIGKSLSETGAKTADWDHLIANPGLEREVTDEDGNVSLAIAIAVKLAEGSNWYAVVSVPKATLFAPLYAVVRDAIV
ATSLAAVLLGLAGWLIARRFVGRISGVIAETAAIAAGKLDVTLKDGEAKDEIGDLSRSLKALLESNRDRARLEAEAEENR
ALQERERAERARIDQAQEADVKFAVGELALGLAKLAEGDMTSALEHPFAATLDETRINFNESVVKLRSALVSFSQNAEVI
QSGTEEIRSAADDLARRTEQQAASVEQTAAALEQITTSVKDSTARAEEAGSMVVRTKENAERSGQIVQRAVEAMNDIEQS
SKSISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAGAAKEIKALISASGGQVRHGVALVRE
TGDALDGIVEEVQQIDRNVHAIVQSAREQSTGLQEINTAVNQMDQATQKNAAMVEESNAAAHTLATEVSALSGRLGQFRL
DTGTGMTSALSRSNAPRPLAAPKIVSSHATIPVPSPARALKKTLAAALGGGSKAAAPADHGWEDF
>Mature_785_residues
MLFKSTTSRNLFSVAACGVIAVIVASGAIFYRSYTEIRSGSIEQMRQIATSEALKVEKNIGGTVHIVDGLNAVLTTMKEM
GDTDRAKADKVLHNMLQANPPVLGIWTGWEPNAFDGKDKDYVGKEGHDTTGRYVPYWVRSGGQITHTALTDYTVAGAGDY
YQLPFTQRKTVIIEPYSYAIDGKDVLMTSVTEPVVIDGKAVGVAGLDLSLQDTAKALSASRPMGAGFLGLVTSAGKIVSH
PDASLIGKSLSETGAKTADWDHLIANPGLEREVTDEDGNVSLAIAIAVKLAEGSNWYAVVSVPKATLFAPLYAVVRDAIV
ATSLAAVLLGLAGWLIARRFVGRISGVIAETAAIAAGKLDVTLKDGEAKDEIGDLSRSLKALLESNRDRARLEAEAEENR
ALQERERAERARIDQAQEADVKFAVGELALGLAKLAEGDMTSALEHPFAATLDETRINFNESVVKLRSALVSFSQNAEVI
QSGTEEIRSAADDLARRTEQQAASVEQTAAALEQITTSVKDSTARAEEAGSMVVRTKENAERSGQIVQRAVEAMNDIEQS
SKSISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRELAQRSAGAAKEIKALISASGGQVRHGVALVRE
TGDALDGIVEEVQQIDRNVHAIVQSAREQSTGLQEINTAVNQMDQATQKNAAMVEESNAAAHTLATEVSALSGRLGQFRL
DTGTGMTSALSRSNAPRPLAAPKIVSSHATIPVPSPARALKKTLAAALGGGSKAAAPADHGWEDF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=267, Percent_Identity=48.314606741573, Blast_Score=195, Evalue=9e-51,
Organism=Escherichia coli, GI1788195, Length=270, Percent_Identity=45.1851851851852, Blast_Score=192, Evalue=9e-50,
Organism=Escherichia coli, GI1787690, Length=246, Percent_Identity=46.7479674796748, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1788194, Length=256, Percent_Identity=44.140625, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1789453, Length=218, Percent_Identity=42.2018348623853, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 82985; Mature: 82985

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKSTTSRNLFSVAACGVIAVIVASGAIFYRSYTEIRSGSIEQMRQIATSEALKVEKNI
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
GGTVHIVDGLNAVLTTMKEMGDTDRAKADKVLHNMLQANPPVLGIWTGWEPNAFDGKDKD
CCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
YVGKEGHDTTGRYVPYWVRSGGQITHTALTDYTVAGAGDYYQLPFTQRKTVIIEPYSYAI
CCCCCCCCCCCCEEEEEECCCCCEEEEEECCEEEECCCCEEECCCCCCCEEEECCCEEEE
DGKDVLMTSVTEPVVIDGKAVGVAGLDLSLQDTAKALSASRPMGAGFLGLVTSAGKIVSH
CCCHHHHHCCCCCEEECCCEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCC
PDASLIGKSLSETGAKTADWDHLIANPGLEREVTDEDGNVSLAIAIAVKLAEGSNWYAVV
CCHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEE
SVPKATLFAPLYAVVRDAIVATSLAAVLLGLAGWLIARRFVGRISGVIAETAAIAAGKLD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VTLKDGEAKDEIGDLSRSLKALLESNRDRARLEAEAEENRALQERERAERARIDQAQEAD
EEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
VKFAVGELALGLAKLAEGDMTSALEHPFAATLDETRINFNESVVKLRSALVSFSQNAEVI
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHH
QSGTEEIRSAADDLARRTEQQAASVEQTAAALEQITTSVKDSTARAEEAGSMVVRTKENA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
ERSGQIVQRAVEAMNDIEQSSKSISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCCHH
VVAQEVRELAQRSAGAAKEIKALISASGGQVRHGVALVRETGDALDGIVEEVQQIDRNVH
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AIVQSAREQSTGLQEINTAVNQMDQATQKNAAMVEESNAAAHTLATEVSALSGRLGQFRL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEE
DTGTGMTSALSRSNAPRPLAAPKIVSSHATIPVPSPARALKKTLAAALGGGSKAAAPADH
CCCCCHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GWEDF
CCCCC
>Mature Secondary Structure
MLFKSTTSRNLFSVAACGVIAVIVASGAIFYRSYTEIRSGSIEQMRQIATSEALKVEKNI
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
GGTVHIVDGLNAVLTTMKEMGDTDRAKADKVLHNMLQANPPVLGIWTGWEPNAFDGKDKD
CCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
YVGKEGHDTTGRYVPYWVRSGGQITHTALTDYTVAGAGDYYQLPFTQRKTVIIEPYSYAI
CCCCCCCCCCCCEEEEEECCCCCEEEEEECCEEEECCCCEEECCCCCCCEEEECCCEEEE
DGKDVLMTSVTEPVVIDGKAVGVAGLDLSLQDTAKALSASRPMGAGFLGLVTSAGKIVSH
CCCHHHHHCCCCCEEECCCEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCC
PDASLIGKSLSETGAKTADWDHLIANPGLEREVTDEDGNVSLAIAIAVKLAEGSNWYAVV
CCHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEEE
SVPKATLFAPLYAVVRDAIVATSLAAVLLGLAGWLIARRFVGRISGVIAETAAIAAGKLD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VTLKDGEAKDEIGDLSRSLKALLESNRDRARLEAEAEENRALQERERAERARIDQAQEAD
EEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCC
VKFAVGELALGLAKLAEGDMTSALEHPFAATLDETRINFNESVVKLRSALVSFSQNAEVI
HHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHH
QSGTEEIRSAADDLARRTEQQAASVEQTAAALEQITTSVKDSTARAEEAGSMVVRTKENA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
ERSGQIVQRAVEAMNDIEQSSKSISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHCCCCCCCHH
VVAQEVRELAQRSAGAAKEIKALISASGGQVRHGVALVRETGDALDGIVEEVQQIDRNVH
HHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AIVQSAREQSTGLQEINTAVNQMDQATQKNAAMVEESNAAAHTLATEVSALSGRLGQFRL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEE
DTGTGMTSALSRSNAPRPLAAPKIVSSHATIPVPSPARALKKTLAAALGGGSKAAAPADH
CCCCCHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GWEDF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]