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The map label for this gene is lhr [C]

Identifier: 209547811

GI number: 209547811

Start: 200206

End: 202731

Strand: Direct

Name: lhr [C]

Synonym: Rleg2_0202

Alternate gene names: 209547811

Gene position: 200206-202731 (Clockwise)

Preceding gene: 209547810

Following gene: 209547812

Centisome position: 4.41

GC content: 64.69

Gene sequence:

>2526_bases
GTGGACCAGATCGATTCCGAAGCCCGCGCTTTGCTGCCTGCCGCCTTTACCCGCTGGTTTGCGGAAAAGGGCTGGCGGCC
GCGCGCCCATCAGCTGGAGCTGCTGTCCCGCGCCGAGGCCGGCGAAAGCACGCTGCTGATTGCGCCCACCGGCGCCGGCA
AGACGCTTGCCGGTTTTCTGCCGTCGCTGACCGACCTCACCCGCCGCGGCAGGATTCCGCCCGGCTCTGCCTTCACCGGC
ATTCATACGCTCTATGTCTCGCCGCTGAAAGCGCTGGCGATCGACATCGAGCGCAATCTGATGAAGCCGGTCGAGGAAAT
GGGCCTGCCGGTCACCGTCGAAAACCGCACCGGCGATACGCCGAACGCCAAGCGCCAGCGCCAGAAGCTCAACCCGCCGG
ATATTCTGCTGACGACGCCCGAACAGGTGGCCCTGCTTCTGGCCAACCGCGAGGCCGAGCGCTTCTTCAAGGATCTGAAA
TATGTCGTCCTCGACGAGCTGCATTCGCTCGTCACCTCCAAGCGCGGCCATATGCTGTCGCTCGGCCTTGCCCGCCTGCG
CAGGCTTGCCCCCGGCCTCCAGACCATCGGCCTGTCGGCGACCGTCGCCGAACCGATGGATCTGCAGAAATGGCTGGTCG
CCCAACAGGAGGGTAGCGGGCAGGAGGGCAGGGAACACCATGCCGGTCTCGTCGTCGTCGAAGGCGGCGCCAAACCCGAT
ATCTCGATCCTGTCGACCGAAGAGCGCATTCCCTGGGCCGGCCATTCCGCCAAATATGCCATTCCCGACGTCTACAACCA
GCTCGTCGACCACCAGACGACGCTGCTCTTCGTCAATACCCGCAGCCAGGCCGAAATGCTCTTCCAGGAACTCTGGACGA
TCAATGACGACAACCTGCCGATCGCGCTCCATCACGGCTCGCTGGATGTCGCCCAGCGCCGCAAGGTCGAGGCGGCGATG
GCCGAAAACCGGCTGCGCGCCGTCGTCGCCACCTCGACGCTCGATCTCGGCATCGACTGGGGCGATGTCGATCTCGTCAT
CCATGTCGGGGCGCCGAAGGGCGCCTCGCGTCTTGCCCAGCGCATCGGCCGCGCCAATCACCGCATGGACGAGCCCTCGA
AGGCGATCCTCGTGCCGGCCAACCGCTTCGAGGTCATGGAGTGCCAGGCCGCCCTCGACGCCAATTATATCGGCGCCCAG
GACACCCCGCCGGTCGGCCGCGGCGCGCTCGACGTGCTCGCCCAGCACGTGCTCGGCATGGCCTGCGCCGAACCTTTCGA
CATGCTGGAACTCTATGATGAGATCATCAGCGCCTCGCCCTATGCCGATCTCAGCTGGGAGACCTTCGAGCGCATCGTCG
ATTTCGTCGCGACCGGCGGTTATGCACTGCGCACCTATGAGCGTTACGCCCGCATCCGCAAGACCAAGGAGGGCCGCTGG
CGCGTTTCCAATCCGGCCGTCGCCCAGCAATATCGCCTCAACCTCGGCACCATTGTCGAAAGCCCGATGCTGAACATCCG
CATGGTCAAACGCGGCGAGGGCGGCCGGATCGGCCGCGGCGGCGCCACGCTTGGAAAGGTCGAGGAATATTTCCTCGAGC
AATTGTCGCCGGGCGACACGTTTGTCTTCTCCGGCAAGGTGCTGCGCTTCGAGGGCATTCGCGAAAACGAATGCCTGGCT
TCGCAGGCCTTTTCGCTCGATCCGAAAATCCCCTCCTATAATGGCGGCAAGTTCCCGCTGTCGACCTATCTCGCCGAGCA
GGTGCGCGCGATGATCGCCGATCCCGACCGCTGGCGCCATCTGCCGGATCAGGTGCGCGACTGGCTGTCGCTGCAGAACG
ACAAGTCGATGCTGCCGAAGCGCGACGAGTTCCTGATCGAAACCTTCCCGCGCGGCAGCCGCGGTTATATGGTCGCCTAT
CCCTTCGAAGGCCGTCTCGCCCATCAGACGCTCGGCATGCTGCTGACCCGCCGGCTGGAGCGGGCGGGCGCCAAACCGCT
CGGCTTCGTCGCCACCGATTATTCGCTGGCCGTCTGGGGCCTCGAGGATATGGGGATGATGATCGCCAATGGCCGGCTCA
GCCTCTCCGACCTCTTCGACGAAGACATGCTCGGCGACGATCTCGAAGCCTGGCTCGACGAATCCTTCCTGCTGAAGCGC
ACCTTCCGCAATTGCGCCGTGATTGCAGGCTTGATCGAGCGCCGTCATACGGGCAAGGAAAAGAGCGGCCGGCAGATCAC
CGTCTCGGCCGATCTGATCTATGACGTGCTGCGCAGCCACGAGCCGGATCACATCCTGTTGCAGGCGACGCGGCAGGATG
CGGCGACGGGACTTTTGGATATTGGCCGCCTTGGCGATATGCTGAGGCGAATCAGGGGCCACATCACCCACCGCCCGCTC
GACCATATTTCTCCGCTCGCCGTGCCGGTGATGCTGGAGATCGGACGCGAGGCGGTGCCGGGCGAGGCCCATGACGCGCT
CTTGGCCGAAGCGGCCGACGATCTGATCGCCGAGGCGATGGCTTGA

Upstream 100 bases:

>100_bases
CAACCTCACGCTTGCCATCAACCACCGCAAGGACCGCTATATCGCCGTGTGAGGCGATGGACGCTCTTCTTTTTCCCCAG
GCTTTCACTACCTTCAGGGC

Downstream 100 bases:

>100_bases
GACTTTTTGGGAATAACGACAGTGATAAACCGCCTGGCGCTGGCGCGCGACATATCCGGATTGGCTGCGATACCCGGGAT
CGAGACGTCGGTCCATGGCA

Product: DEAD/DEAH box helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 841; Mature: 841

Protein sequence:

>841_residues
MDQIDSEARALLPAAFTRWFAEKGWRPRAHQLELLSRAEAGESTLLIAPTGAGKTLAGFLPSLTDLTRRGRIPPGSAFTG
IHTLYVSPLKALAIDIERNLMKPVEEMGLPVTVENRTGDTPNAKRQRQKLNPPDILLTTPEQVALLLANREAERFFKDLK
YVVLDELHSLVTSKRGHMLSLGLARLRRLAPGLQTIGLSATVAEPMDLQKWLVAQQEGSGQEGREHHAGLVVVEGGAKPD
ISILSTEERIPWAGHSAKYAIPDVYNQLVDHQTTLLFVNTRSQAEMLFQELWTINDDNLPIALHHGSLDVAQRRKVEAAM
AENRLRAVVATSTLDLGIDWGDVDLVIHVGAPKGASRLAQRIGRANHRMDEPSKAILVPANRFEVMECQAALDANYIGAQ
DTPPVGRGALDVLAQHVLGMACAEPFDMLELYDEIISASPYADLSWETFERIVDFVATGGYALRTYERYARIRKTKEGRW
RVSNPAVAQQYRLNLGTIVESPMLNIRMVKRGEGGRIGRGGATLGKVEEYFLEQLSPGDTFVFSGKVLRFEGIRENECLA
SQAFSLDPKIPSYNGGKFPLSTYLAEQVRAMIADPDRWRHLPDQVRDWLSLQNDKSMLPKRDEFLIETFPRGSRGYMVAY
PFEGRLAHQTLGMLLTRRLERAGAKPLGFVATDYSLAVWGLEDMGMMIANGRLSLSDLFDEDMLGDDLEAWLDESFLLKR
TFRNCAVIAGLIERRHTGKEKSGRQITVSADLIYDVLRSHEPDHILLQATRQDAATGLLDIGRLGDMLRRIRGHITHRPL
DHISPLAVPVMLEIGREAVPGEAHDALLAEAADDLIAEAMA

Sequences:

>Translated_841_residues
MDQIDSEARALLPAAFTRWFAEKGWRPRAHQLELLSRAEAGESTLLIAPTGAGKTLAGFLPSLTDLTRRGRIPPGSAFTG
IHTLYVSPLKALAIDIERNLMKPVEEMGLPVTVENRTGDTPNAKRQRQKLNPPDILLTTPEQVALLLANREAERFFKDLK
YVVLDELHSLVTSKRGHMLSLGLARLRRLAPGLQTIGLSATVAEPMDLQKWLVAQQEGSGQEGREHHAGLVVVEGGAKPD
ISILSTEERIPWAGHSAKYAIPDVYNQLVDHQTTLLFVNTRSQAEMLFQELWTINDDNLPIALHHGSLDVAQRRKVEAAM
AENRLRAVVATSTLDLGIDWGDVDLVIHVGAPKGASRLAQRIGRANHRMDEPSKAILVPANRFEVMECQAALDANYIGAQ
DTPPVGRGALDVLAQHVLGMACAEPFDMLELYDEIISASPYADLSWETFERIVDFVATGGYALRTYERYARIRKTKEGRW
RVSNPAVAQQYRLNLGTIVESPMLNIRMVKRGEGGRIGRGGATLGKVEEYFLEQLSPGDTFVFSGKVLRFEGIRENECLA
SQAFSLDPKIPSYNGGKFPLSTYLAEQVRAMIADPDRWRHLPDQVRDWLSLQNDKSMLPKRDEFLIETFPRGSRGYMVAY
PFEGRLAHQTLGMLLTRRLERAGAKPLGFVATDYSLAVWGLEDMGMMIANGRLSLSDLFDEDMLGDDLEAWLDESFLLKR
TFRNCAVIAGLIERRHTGKEKSGRQITVSADLIYDVLRSHEPDHILLQATRQDAATGLLDIGRLGDMLRRIRGHITHRPL
DHISPLAVPVMLEIGREAVPGEAHDALLAEAADDLIAEAMA
>Mature_841_residues
MDQIDSEARALLPAAFTRWFAEKGWRPRAHQLELLSRAEAGESTLLIAPTGAGKTLAGFLPSLTDLTRRGRIPPGSAFTG
IHTLYVSPLKALAIDIERNLMKPVEEMGLPVTVENRTGDTPNAKRQRQKLNPPDILLTTPEQVALLLANREAERFFKDLK
YVVLDELHSLVTSKRGHMLSLGLARLRRLAPGLQTIGLSATVAEPMDLQKWLVAQQEGSGQEGREHHAGLVVVEGGAKPD
ISILSTEERIPWAGHSAKYAIPDVYNQLVDHQTTLLFVNTRSQAEMLFQELWTINDDNLPIALHHGSLDVAQRRKVEAAM
AENRLRAVVATSTLDLGIDWGDVDLVIHVGAPKGASRLAQRIGRANHRMDEPSKAILVPANRFEVMECQAALDANYIGAQ
DTPPVGRGALDVLAQHVLGMACAEPFDMLELYDEIISASPYADLSWETFERIVDFVATGGYALRTYERYARIRKTKEGRW
RVSNPAVAQQYRLNLGTIVESPMLNIRMVKRGEGGRIGRGGATLGKVEEYFLEQLSPGDTFVFSGKVLRFEGIRENECLA
SQAFSLDPKIPSYNGGKFPLSTYLAEQVRAMIADPDRWRHLPDQVRDWLSLQNDKSMLPKRDEFLIETFPRGSRGYMVAY
PFEGRLAHQTLGMLLTRRLERAGAKPLGFVATDYSLAVWGLEDMGMMIANGRLSLSDLFDEDMLGDDLEAWLDESFLLKR
TFRNCAVIAGLIERRHTGKEKSGRQITVSADLIYDVLRSHEPDHILLQATRQDAATGLLDIGRLGDMLRRIRGHITHRPL
DHISPLAVPVMLEIGREAVPGEAHDALLAEAADDLIAEAMA

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI38569503, Length=366, Percent_Identity=25.4098360655738, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI38569505, Length=366, Percent_Identity=25.4098360655738, Blast_Score=70, Evalue=7e-12,
Organism=Escherichia coli, GI1787942, Length=860, Percent_Identity=26.2790697674419, Blast_Score=223, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI115533224, Length=363, Percent_Identity=24.5179063360882, Blast_Score=70, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320497, Length=422, Percent_Identity=25.8293838862559, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI9755332, Length=361, Percent_Identity=23.8227146814404, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 93376; Mature: 93376

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQIDSEARALLPAAFTRWFAEKGWRPRAHQLELLSRAEAGESTLLIAPTGAGKTLAGFL
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHH
PSLTDLTRRGRIPPGSAFTGIHTLYVSPLKALAIDIERNLMKPVEEMGLPVTVENRTGDT
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
PNAKRQRQKLNPPDILLTTPEQVALLLANREAERFFKDLKYVVLDELHSLVTSKRGHMLS
CCHHHHHHCCCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LGLARLRRLAPGLQTIGLSATVAEPMDLQKWLVAQQEGSGQEGREHHAGLVVVEGGAKPD
HHHHHHHHHCCCHHHCCCCEECCCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCC
ISILSTEERIPWAGHSAKYAIPDVYNQLVDHQTTLLFVNTRSQAEMLFQELWTINDDNLP
CEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCCCCE
IALHHGSLDVAQRRKVEAAMAENRLRAVVATSTLDLGIDWGDVDLVIHVGAPKGASRLAQ
EEEECCCCCHHHHHHHHHHHHHHHHEEEEEECEEEECCCCCCEEEEEEECCCCCHHHHHH
RIGRANHRMDEPSKAILVPANRFEVMECQAALDANYIGAQDTPPVGRGALDVLAQHVLGM
HHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ACAEPFDMLELYDEIISASPYADLSWETFERIVDFVATGGYALRTYERYARIRKTKEGRW
HHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCE
RVSNPAVAQQYRLNLGTIVESPMLNIRMVKRGEGGRIGRGGATLGKVEEYFLEQLSPGDT
EECCCHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCE
FVFSGKVLRFEGIRENECLASQAFSLDPKIPSYNGGKFPLSTYLAEQVRAMIADPDRWRH
EEECCEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHC
LPDQVRDWLSLQNDKSMLPKRDEFLIETFPRGSRGYMVAYPFEGRLAHQTLGMLLTRRLE
CHHHHHHHHHCCCCHHCCCCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
RAGAKPLGFVATDYSLAVWGLEDMGMMIANGRLSLSDLFDEDMLGDDLEAWLDESFLLKR
HCCCCCCEEEEECCEEEEECHHHCCEEEECCCCCHHHHHCHHHCCCHHHHHHCHHHHHHH
TFRNCAVIAGLIERRHTGKEKSGRQITVSADLIYDVLRSHEPDHILLQATRQDAATGLLD
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHH
IGRLGDMLRRIRGHITHRPLDHISPLAVPVMLEIGREAVPGEAHDALLAEAADDLIAEAM
HHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MDQIDSEARALLPAAFTRWFAEKGWRPRAHQLELLSRAEAGESTLLIAPTGAGKTLAGFL
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHH
PSLTDLTRRGRIPPGSAFTGIHTLYVSPLKALAIDIERNLMKPVEEMGLPVTVENRTGDT
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
PNAKRQRQKLNPPDILLTTPEQVALLLANREAERFFKDLKYVVLDELHSLVTSKRGHMLS
CCHHHHHHCCCCCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LGLARLRRLAPGLQTIGLSATVAEPMDLQKWLVAQQEGSGQEGREHHAGLVVVEGGAKPD
HHHHHHHHHCCCHHHCCCCEECCCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCC
ISILSTEERIPWAGHSAKYAIPDVYNQLVDHQTTLLFVNTRSQAEMLFQELWTINDDNLP
CEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHCCCCCCCE
IALHHGSLDVAQRRKVEAAMAENRLRAVVATSTLDLGIDWGDVDLVIHVGAPKGASRLAQ
EEEECCCCCHHHHHHHHHHHHHHHHEEEEEECEEEECCCCCCEEEEEEECCCCCHHHHHH
RIGRANHRMDEPSKAILVPANRFEVMECQAALDANYIGAQDTPPVGRGALDVLAQHVLGM
HHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ACAEPFDMLELYDEIISASPYADLSWETFERIVDFVATGGYALRTYERYARIRKTKEGRW
HHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCE
RVSNPAVAQQYRLNLGTIVESPMLNIRMVKRGEGGRIGRGGATLGKVEEYFLEQLSPGDT
EECCCHHHHHHHCCHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCE
FVFSGKVLRFEGIRENECLASQAFSLDPKIPSYNGGKFPLSTYLAEQVRAMIADPDRWRH
EEECCEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHC
LPDQVRDWLSLQNDKSMLPKRDEFLIETFPRGSRGYMVAYPFEGRLAHQTLGMLLTRRLE
CHHHHHHHHHCCCCHHCCCCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
RAGAKPLGFVATDYSLAVWGLEDMGMMIANGRLSLSDLFDEDMLGDDLEAWLDESFLLKR
HCCCCCCEEEEECCEEEEECHHHCCEEEECCCCCHHHHHCHHHCCCHHHHHHCHHHHHHH
TFRNCAVIAGLIERRHTGKEKSGRQITVSADLIYDVLRSHEPDHILLQATRQDAATGLLD
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHH
IGRLGDMLRRIRGHITHRPLDHISPLAVPVMLEIGREAVPGEAHDALLAEAADDLIAEAM
HHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]