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The map label for this gene is bioH [H]

Identifier: 209547722

GI number: 209547722

Start: 103672

End: 104535

Strand: Direct

Name: bioH [H]

Synonym: Rleg2_0111

Alternate gene names: 209547722

Gene position: 103672-104535 (Clockwise)

Preceding gene: 209547718

Following gene: 209547723

Centisome position: 2.28

GC content: 60.65

Gene sequence:

>864_bases
ATGAACGCGACGATAAGATACCTTCGGTCTGCCACCTGCTACGCCGAGGCGCCAAATCTCTGGGTCAATGTTGGGGAGAC
GCCTTTCGTCTATCGCGACCTCGGTCCCCAAGGCGGCGTGCCGGTCATTCTTCTCAACCATTGGGGCGCGGTGTTGGACA
ATTTCGATCCTCGGATTGTCGACGGTCTGGCCAGCAAGCATCACGTAATCGCGATCGATTACCGGGGGATCGGCGCCTCA
GGCGGCACGGCCCCTGTGACCATCGACGAGATGGCGCGCGACGCGATCGCGTTGATCCGAGCGCTTGGGTTCAAACAAGT
CGATCTGCTCGGTTTTTCCCTTGGGGGATTTGTCGCGCAGGACATCGTGCTGAAGGCGCCGGACCTTGTGCGGAAACTCA
TTTTGACTGGAACGGGCCCGGCCGGCGGAAAAGGGATAGAGAAGGTCGGAGCCGTGTCCTGGCCGCTGATGATCAAGGGT
CTGCTGACGCTGCGCGACCCGAAAACCTATTTGTTTTTCACCTCCACCGCCAATGGTCGCCGAGCCGCGAAAGCCTTTCT
CGATCGCCTGAAAGAGCGCAAGGCGGGAAGGGACAAGAGCCCGACGCCAAGGGCCTTCCTGCGGCAACTCAAGGCGATCA
AGGCCTGGGGGCGGCAGGCGCCTCAGGATCTCGGCCGTATCACTATCCCGGTCCTGATCGCCAATGGCGACAGTGATATC
ATGGTCCCCACGGTCAACAGCGCCGATATGGCCAGGCGCATTCCGGGCGCGCAACTGGTTACCTATAACGACGCCGGACA
TGGCGGGATCTTCCAGAACCACGCCGATTTCGTGCCGAAGGCTTTGTCCTTCCTTGCAGCCTGA

Upstream 100 bases:

>100_bases
AGTTGGTTTCCTTTTGCGCGAAAGTCGGTGGTCGATGCGGAAGGGCAAGGATAATGGCGATGATGAGCGTGCCGGTACGA
GCCGGGGTGTGGAGTAAACC

Downstream 100 bases:

>100_bases
CATCCCACCAGACTTCGAATTGGAGAAAGCCTCATGAAGGCATTCGTCGTTGATAAGTACAAAAAGAAGGGCGCTTTGCG
CCTGGCCAGCCTGCCGGAAC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Biotin synthesis protein BioH [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNATIRYLRSATCYAEAPNLWVNVGETPFVYRDLGPQGGVPVILLNHWGAVLDNFDPRIVDGLASKHHVIAIDYRGIGAS
GGTAPVTIDEMARDAIALIRALGFKQVDLLGFSLGGFVAQDIVLKAPDLVRKLILTGTGPAGGKGIEKVGAVSWPLMIKG
LLTLRDPKTYLFFTSTANGRRAAKAFLDRLKERKAGRDKSPTPRAFLRQLKAIKAWGRQAPQDLGRITIPVLIANGDSDI
MVPTVNSADMARRIPGAQLVTYNDAGHGGIFQNHADFVPKALSFLAA

Sequences:

>Translated_287_residues
MNATIRYLRSATCYAEAPNLWVNVGETPFVYRDLGPQGGVPVILLNHWGAVLDNFDPRIVDGLASKHHVIAIDYRGIGAS
GGTAPVTIDEMARDAIALIRALGFKQVDLLGFSLGGFVAQDIVLKAPDLVRKLILTGTGPAGGKGIEKVGAVSWPLMIKG
LLTLRDPKTYLFFTSTANGRRAAKAFLDRLKERKAGRDKSPTPRAFLRQLKAIKAWGRQAPQDLGRITIPVLIANGDSDI
MVPTVNSADMARRIPGAQLVTYNDAGHGGIFQNHADFVPKALSFLAA
>Mature_287_residues
MNATIRYLRSATCYAEAPNLWVNVGETPFVYRDLGPQGGVPVILLNHWGAVLDNFDPRIVDGLASKHHVIAIDYRGIGAS
GGTAPVTIDEMARDAIALIRALGFKQVDLLGFSLGGFVAQDIVLKAPDLVRKLILTGTGPAGGKGIEKVGAVSWPLMIKG
LLTLRDPKTYLFFTSTANGRRAAKAFLDRLKERKAGRDKSPTPRAFLRQLKAIKAWGRQAPQDLGRITIPVLIANGDSDI
MVPTVNSADMARRIPGAQLVTYNDAGHGGIFQNHADFVPKALSFLAA

Specific function: Shows carboxylesterase activity with a preference for short chain fatty acid esters (acyl chain length of up to 6 carbons). Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010076 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 30876; Mature: 30876

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATIRYLRSATCYAEAPNLWVNVGETPFVYRDLGPQGGVPVILLNHWGAVLDNFDPRIV
CCCHHHHHHHCHHEECCCCEEEECCCCCEEEECCCCCCCCCEEEECCCHHHHCCCCHHHH
DGLASKHHVIAIDYRGIGASGGTAPVTIDEMARDAIALIRALGFKQVDLLGFSLGGFVAQ
HHHCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHEECHHHHHHH
DIVLKAPDLVRKLILTGTGPAGGKGIEKVGAVSWPLMIKGLLTLRDPKTYLFFTSTANGR
HHHHCCHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHEEECCCEEEEEEECCCCH
RAAKAFLDRLKERKAGRDKSPTPRAFLRQLKAIKAWGRQAPQDLGRITIPVLIANGDSDI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEEECCCCCE
MVPTVNSADMARRIPGAQLVTYNDAGHGGIFQNHADFVPKALSFLAA
EEEECCCHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNATIRYLRSATCYAEAPNLWVNVGETPFVYRDLGPQGGVPVILLNHWGAVLDNFDPRIV
CCCHHHHHHHCHHEECCCCEEEECCCCCEEEECCCCCCCCCEEEECCCHHHHCCCCHHHH
DGLASKHHVIAIDYRGIGASGGTAPVTIDEMARDAIALIRALGFKQVDLLGFSLGGFVAQ
HHHCCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHHHHEECHHHHHHH
DIVLKAPDLVRKLILTGTGPAGGKGIEKVGAVSWPLMIKGLLTLRDPKTYLFFTSTANGR
HHHHCCHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHEEECCCEEEEEEECCCCH
RAAKAFLDRLKERKAGRDKSPTPRAFLRQLKAIKAWGRQAPQDLGRITIPVLIANGDSDI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCEEEEEEEECCCCCE
MVPTVNSADMARRIPGAQLVTYNDAGHGGIFQNHADFVPKALSFLAA
EEEECCCHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA