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The map label for this gene is rbsK [H]

Identifier: 209547665

GI number: 209547665

Start: 55072

End: 55971

Strand: Reverse

Name: rbsK [H]

Synonym: Rleg2_0053

Alternate gene names: 209547665

Gene position: 55971-55072 (Counterclockwise)

Preceding gene: 209547666

Following gene: 209547664

Centisome position: 1.23

GC content: 65.44

Gene sequence:

>900_bases
ATGATCACAGTTTTCGGGTCCATCAACATGGATCTCATCGCCACCACCGAACGTCTGCCGAAGCCCGGCGAGACGGTGGC
CGGCAATGGTTTTGCCACCGCTGCCGGCGGCAAGGGCGCCAACCAGGCGCTGGCCGCGCGGCGCGCCGGCCGCTATGTCC
ATATGGCCGGCGCTGTCGGCAAGGATAGCTTCGCCGCCGATGCCCTTGCCCTGCTCGATGATGCGGGAACCGATCTTTCT
CTGGTCAAGCATGTCGACGGTCCCACCGGCACGGCGCTGATCCTTGTCGGCGGCGACGGCGAAAACATGATTGCCGTCGT
TCCCGGCGCCAATGGCCTGGTCACCCCCAACGATGCCGAGACGGCAATCGGCGGCATGACGGAAGGCGATATCCTGATGC
TGCAGTTCGAAGTGCCGGCCGATGCCGTCGAACGCGCGCTCTCGGCCGCCCGCGCCAAGGGCGTCACCAGCATCCTCAAC
CTTGCTCCCTTGATTCCCGATGCGCCGCGTCTTGGCCGGCTTGCCGATATCGTCATTGCCAATGAGACCGAGTTCGAGCG
GCTCGCCGGACAGGACGGCATGGACACACCAGCGCGCGAAGCAGCCCTGACACGACTGCATGCCGAAACCGGCCAGACGC
TGATCGTGACGCTTGGCGGCGACGGCGTCATCGCCATCCGCGACGGGGCGATCTCAAGGGCGCAGGGTCTGAAGATCGAA
CCGGTCGACACGGTCGGCGCCGGTGACACTTTCTGCGGCTATTTCGCAGCGAGCCTCGACGAGGGCCTGGATTTTGCCTC
GGCGCTGCGCCGTGCCGCCGTTGCCGGTTCACTCGCCTGCCTCAAATCCGGGGCACAGCCTTCGATCCCTCGGGGTGAGG
ACGTCGTAGCCAGGATATAA

Upstream 100 bases:

>100_bases
GGAAAGCCGCACCGGTCTTCTCAAGCTCAGGGTGGTTGACGAAGAGTGACCGCTTCGGGCAGTGTCTCGCCCGCATGCGC
CAAAGGACGGGACACCCCTG

Downstream 100 bases:

>100_bases
GCCGCGTCTCTTTGCGAAGCCGCCGGCAGAGCCCTTAATTTTAAGGGGAATTCTTGCCTTTTTGCCGCGGCCCACGGCTC
AAGTTTCATTCAAATTTAAC

Product: PfkB domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MITVFGSINMDLIATTERLPKPGETVAGNGFATAAGGKGANQALAARRAGRYVHMAGAVGKDSFAADALALLDDAGTDLS
LVKHVDGPTGTALILVGGDGENMIAVVPGANGLVTPNDAETAIGGMTEGDILMLQFEVPADAVERALSAARAKGVTSILN
LAPLIPDAPRLGRLADIVIANETEFERLAGQDGMDTPAREAALTRLHAETGQTLIVTLGGDGVIAIRDGAISRAQGLKIE
PVDTVGAGDTFCGYFAASLDEGLDFASALRRAAVAGSLACLKSGAQPSIPRGEDVVARI

Sequences:

>Translated_299_residues
MITVFGSINMDLIATTERLPKPGETVAGNGFATAAGGKGANQALAARRAGRYVHMAGAVGKDSFAADALALLDDAGTDLS
LVKHVDGPTGTALILVGGDGENMIAVVPGANGLVTPNDAETAIGGMTEGDILMLQFEVPADAVERALSAARAKGVTSILN
LAPLIPDAPRLGRLADIVIANETEFERLAGQDGMDTPAREAALTRLHAETGQTLIVTLGGDGVIAIRDGAISRAQGLKIE
PVDTVGAGDTFCGYFAASLDEGLDFASALRRAAVAGSLACLKSGAQPSIPRGEDVVARI
>Mature_299_residues
MITVFGSINMDLIATTERLPKPGETVAGNGFATAAGGKGANQALAARRAGRYVHMAGAVGKDSFAADALALLDDAGTDLS
LVKHVDGPTGTALILVGGDGENMIAVVPGANGLVTPNDAETAIGGMTEGDILMLQFEVPADAVERALSAARAKGVTSILN
LAPLIPDAPRLGRLADIVIANETEFERLAGQDGMDTPAREAALTRLHAETGQTLIVTLGGDGVIAIRDGAISRAQGLKIE
PVDTVGAGDTFCGYFAASLDEGLDFASALRRAAVAGSLACLKSGAQPSIPRGEDVVARI

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=299, Percent_Identity=36.7892976588629, Blast_Score=156, Evalue=2e-38,
Organism=Escherichia coli, GI1790193, Length=298, Percent_Identity=38.255033557047, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI87082343, Length=284, Percent_Identity=29.2253521126761, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17532905, Length=298, Percent_Identity=36.9127516778523, Blast_Score=161, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6319884, Length=329, Percent_Identity=31.6109422492401, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20128807, Length=267, Percent_Identity=37.0786516853933, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24583886, Length=305, Percent_Identity=31.4754098360656, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30310; Mature: 30310

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVFGSINMDLIATTERLPKPGETVAGNGFATAAGGKGANQALAARRAGRYVHMAGAVG
CEEEEECCCEEEEEEHHHCCCCCCEECCCCEEECCCCCCCHHHHHHHHCCCEEEEECCCC
KDSFAADALALLDDAGTDLSLVKHVDGPTGTALILVGGDGENMIAVVPGANGLVTPNDAE
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCH
TAIGGMTEGDILMLQFEVPADAVERALSAARAKGVTSILNLAPLIPDAPRLGRLADIVIA
HHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
NETEFERLAGQDGMDTPAREAALTRLHAETGQTLIVTLGGDGVIAIRDGAISRAQGLKIE
CCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCHHHCCCEEC
PVDTVGAGDTFCGYFAASLDEGLDFASALRRAAVAGSLACLKSGAQPSIPRGEDVVARI
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECC
>Mature Secondary Structure
MITVFGSINMDLIATTERLPKPGETVAGNGFATAAGGKGANQALAARRAGRYVHMAGAVG
CEEEEECCCEEEEEEHHHCCCCCCEECCCCEEECCCCCCCHHHHHHHHCCCEEEEECCCC
KDSFAADALALLDDAGTDLSLVKHVDGPTGTALILVGGDGENMIAVVPGANGLVTPNDAE
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCH
TAIGGMTEGDILMLQFEVPADAVERALSAARAKGVTSILNLAPLIPDAPRLGRLADIVIA
HHHCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
NETEFERLAGQDGMDTPAREAALTRLHAETGQTLIVTLGGDGVIAIRDGAISRAQGLKIE
CCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCHHHCCCEEC
PVDTVGAGDTFCGYFAASLDEGLDFASALRRAAVAGSLACLKSGAQPSIPRGEDVVARI
CCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]