Click here to switch to the map view.

The map label for this gene is fimZ

Identifier: 209400942

GI number: 209400942

Start: 659583

End: 660215

Strand: Reverse

Name: fimZ

Synonym: ECH74115_0636

Alternate gene names: 209400942

Gene position: 660215-659583 (Counterclockwise)

Preceding gene: 209396048

Following gene: 209398701

Centisome position: 11.85

GC content: 36.81

Gene sequence:

>633_bases
ATGAAACCAACGTCGGTGATCATTATGGACACTCATCCTATCATCAGAATGTCTATTGAAGTTCTGTTGCAAAAAAACAG
TGAATTGCAGATTGTCCTGAAAACGGATGATTACCGCATAACCATCGATTATCTCCGAACCCGTCCTGTTGATTTAATCA
TTATGGATATAGACTTGCCCGGAACAGACGGTTTTACCTTCCTGAAAAGGATCAAACAAATCCAGAGCACAGTGAAAGTG
TTATTTTTATCATCGAAATCAGAATGCTTTTATGCTGGCAGAGCGATACAAGCTGGTGCTAACGGTTTTGTCAGTAAATG
CAATGATCAGAATGATATTTTTCATGCCGTTCAGATGATCCTCTCCGGATACACGTTTTTTCCCAGCGAAACGCTTAACT
ATATAAAAAGCAATAAATGTAGTACGAATAGTTCAACGGTCACTGTGCTATCTAATCGTGAAGTGACCATATTACGTTAT
CTAGTTAGCGGATTATCTAATAAAGAAATTGCCGATAAGTTATTACTTAGCAATAAAACAGTTAGTGCGCATAAATCTAA
TATTTATGGCAAGCTAGGTTTGCATTCAATTGTAGAGCTTATCGACTACGCCAAATTATACGAATTAATATAA

Upstream 100 bases:

>100_bases
ACCGCTGCGCGTCTGAATCAAGAAAACCCGTATTTTCATGTATCAAAGTACAATTTACCGCCCTAACGGAAAATTGTCCG
CTCCTATGAGACTGGTAACT

Downstream 100 bases:

>100_bases
TATTAATTATAATTGATCATAAATATCGCATCCGCTTTCGCCACACCTGGCCGAACACCGCTGGCTAACGCTCGATAATT
GGCAAAAAAGTTTAGTGTGA

Product: transcriptional regulator FimZ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKV
LFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI

Sequences:

>Translated_210_residues
MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKV
LFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI
>Mature_210_residues
MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKV
LFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI

Specific function: Unknown

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1786747, Length=210, Percent_Identity=100, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1788712, Length=201, Percent_Identity=32.3383084577114, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788222, Length=205, Percent_Identity=27.8048780487805, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=28.5, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=29.5918367346939, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI1788546, Length=206, Percent_Identity=27.1844660194175, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787473, Length=187, Percent_Identity=24.5989304812834, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIMZ_ECO57 (P0AEL9)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   E90703
- RefSeq:   NP_286284.1
- RefSeq:   NP_308624.1
- ProteinModelPortal:   P0AEL9
- SMR:   P0AEL9
- EnsemblBacteria:   EBESCT00000028990
- EnsemblBacteria:   EBESCT00000057750
- GeneID:   916954
- GeneID:   957547
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0693
- KEGG:   ecs:ECs0597
- GeneTree:   EBGT00050000008652
- HOGENOM:   HBG753323
- OMA:   SKSESFY
- ProtClustDB:   PRK09935
- BioCyc:   ECOL83334:ECS0597-MONOMER
- GO:   GO:0005737
- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421
- SMART:   SM00448

Pfam domain/function: PF00196 GerE; PF00072 Response_reg; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 23664; Mature: 23664

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLP
CCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCEEEEEEEEECC
GTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMI
CCCHHHHHHHHHHHHHHHHEEEECCCCCEEEECCEEECCCCCHHHCCCCCHHHHHHHHHH
LSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRYLVSGLSNKEIADKLLLSNKT
HCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCC
VSAHKSNIYGKLGLHSIVELIDYAKLYELI
CCHHCCCCEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLP
CCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCEEEEEEEEECC
GTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMI
CCCHHHHHHHHHHHHHHHHEEEECCCCCEEEECCEEECCCCCHHHCCCCCHHHHHHHHHH
LSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRYLVSGLSNKEIADKLLLSNKT
HCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCCC
VSAHKSNIYGKLGLHSIVELIDYAKLYELI
CCHHCCCCEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796