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The map label for this gene is yrdA

Identifier: 209400737

GI number: 209400737

Start: 4267328

End: 4267882

Strand: Direct

Name: yrdA

Synonym: ECH74115_4603

Alternate gene names: 209400737

Gene position: 4267328-4267882 (Clockwise)

Preceding gene: 209400549

Following gene: 209400361

Centisome position: 76.58

GC content: 48.65

Gene sequence:

>555_bases
ATGTCTGATGTTTTACGCCCATACCGCGATCTTTTTCCACAAATCGGTCAGCGCGTAATGATCGACGATAGCAGTGTCGT
GATTGGTGACGTTCGTCTGGCTGATGATGTGGGGATCTGGCCGCTCGTTGTGATTCGTGGAGATGTACATTATGTACAGA
TCGGAGCACGCACCAATATCCAGGATGGCAGTATGTTGCATGTCACTCATAAATCCTCGTACAACCCAGATGGCAACCCA
TTAACCATTGGCGAAGATGTCACTGTTGGTCACAAGGTGATGCTCCACGGCTGCACCATTGGCAATCGAGTTTTGGTTGG
GATGGGCTCAATTTTACTTGATGGCGCAATAGTAGAAGATGATGTGATGATTGGTGCGGGTAGTCTGGTCCCACAAAATA
AACGGCTGGAGAGCGGATATCTGTATCTCGGTAGTCCCGTCAAACAGATCCGCCCGTTAAGTGATGAAGAGAAGGCTGGG
TTACGCTATTCCGCGAATAATTACGTGAAATGGAAGGACGAATATCTGGATCAGGGTAACCAGACCCAGCCTTGA

Upstream 100 bases:

>100_bases
ATTCGCACACAAAACGGTGCTTTTTTGCATACTAAAAGACTTGCACAAGGCCAATAATGCCCCCAAAGTCATTAGTAAAT
CATTTATTGCTGAGGTAAGT

Downstream 100 bases:

>100_bases
TCATCTTCACTTTGTTCCTGAATTAAGTTTTCCGCTTCTTCTTCCAAGTCCCAGCGATGCTGACGAAAACTCGCTAACCA
CTGCTCTGGCGTATCTCCTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVVIRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNP
LTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
LRYSANNYVKWKDEYLDQGNQTQP

Sequences:

>Translated_184_residues
MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVVIRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNP
LTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
LRYSANNYVKWKDEYLDQGNQTQP
>Mature_183_residues
SDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVVIRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPL
TIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAGL
RYSANNYVKWKDEYLDQGNQTQP

Specific function: Unknown

COG id: COG0663

COG function: function code R; Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-class carbonic anhydrase family

Homologues:

Organism=Escherichia coli, GI87082240, Length=184, Percent_Identity=100, Blast_Score=372, Evalue=1e-105,
Organism=Escherichia coli, GI87081681, Length=177, Percent_Identity=32.2033898305085, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787667, Length=161, Percent_Identity=32.9192546583851, Blast_Score=97, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YRDA_ECOLI (P0A9W9)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   B65120
- RefSeq:   AP_004511.1
- RefSeq:   NP_417738.4
- ProteinModelPortal:   P0A9W9
- SMR:   P0A9W9
- DIP:   DIP-48232N
- STRING:   P0A9W9
- EnsemblBacteria:   EBESCT00000003234
- EnsemblBacteria:   EBESCT00000015348
- GeneID:   947775
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5710
- KEGG:   eco:b3279
- EchoBASE:   EB2687
- EcoGene:   EG12838
- eggNOG:   COG0663
- GeneTree:   EBGT00050000010015
- HOGENOM:   HBG621238
- OMA:   VNYVSIG
- ProtClustDB:   CLSK950279
- BioCyc:   EcoCyc:G7696-MONOMER
- Genevestigator:   P0A9W9
- InterPro:   IPR011004

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: NA

Molecular weight: Translated: 20245; Mature: 20114

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVVIRGDVHYVQIGARTNI
CCHHHHHHHHHHHHHCCEEEEECCCEEEEEEEEECCCCCEEEEEEECCEEEEEECCCCCC
QDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVED
CCCCEEEEEECCCCCCCCCEEEECCCCCCCEEEEEEECCCCCEEEEECCCHHCCCEEECC
DVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAGLRYSANNYVKWKDEYLDQGN
CEEEECCCCCCCCCCCCCCEEEECCCHHHHCCCCCCCCCCEEECCCCEEEECHHHHCCCC
QTQP
CCCC
>Mature Secondary Structure 
SDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVVIRGDVHYVQIGARTNI
CHHHHHHHHHHHHHCCEEEEECCCEEEEEEEEECCCCCEEEEEEECCEEEEEECCCCCC
QDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGNRVLVGMGSILLDGAIVED
CCCCEEEEEECCCCCCCCCEEEECCCCCCCEEEEEEECCCCCEEEEECCCHHCCCEEECC
DVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAGLRYSANNYVKWKDEYLDQGN
CEEEECCCCCCCCCCCCCCEEEECCCHHHHCCCCCCCCCCEEECCCCEEEECHHHHCCCC
QTQP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 10493123