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The map label for this gene is yhcM

Identifier: 209400662

GI number: 209400662

Start: 4215873

End: 4217000

Strand: Reverse

Name: yhcM

Synonym: ECH74115_4549

Alternate gene names: 209400662

Gene position: 4217000-4215873 (Counterclockwise)

Preceding gene: 209399586

Following gene: 209395901

Centisome position: 75.68

GC content: 51.77

Gene sequence:

>1128_bases
ATGCAAAGCGTTACTCCAACATCGCAATACCTGAAGGCGCTCAATGAAGGCAGCCATCAACCCGACGACGTTCAAAAAGA
GGCCGTCAGCCGCTTGGAAATTATTTATCAGGAACTCATCAATAGCACGCCACCAGCCCCCAGGACGAGTGGGCTAATGG
CGCGGGTCGGTAAGCTGTGGGGTAAACGGGAAGACACAAAGCATACGCCAGTGCGTGGCTTATATATGTGGGGCGGTGTA
GGACGCGGGAAAACCTGGCTGATGGACCTTTTCTATCAAAGCCTGCCGGGAGAGCGGAAACAGCGCCTGCACTTTCACCG
TTTTATGCTGCGGGTGCATGAAGAGCTAACTGCCTTACAGGGGCAGACCGATCCGCTGGAAATTATTGCTGATCGTTTTA
AAGCAGAAACTGACGTGCTCTGTTTTGACGAATTTTTTGTCTCTGATATTACCGATGCCATGCTACTTGGCGGCCTGATG
AAAGCCCTGTTCGCCCGCGGTATTACCCTGGTAGCGACGTCAAATATTCCGCCGGACGAACTTTATCGAAATGGCTTGCA
ACGTGCGCGTTTTCTGCCTGCAATCGATGCCATTAAACAGCATTGTGATGTAATGAACGTGGACGCTGGTGTTGATTATC
GTCTGCGTACACTCACTCAGGCGCATCTGTGGCTTTCGCCACTCCACGATGAAACCCGGGCGCAAATGGATAAACTATGG
TTGGCGCTGGCGGGGGGGAAACGAGAAAATTCACCGACGTTAGAAATCAACCATCGGCCATTAGCGACAATGGGCGTCGA
GAACCAGACGCTGGCGGTCTCTTTTACTACGCTGTGCGTCGACGCCCGCAGTCAGCATGACTATATTGCGCTCTCACGTC
TCTTTCATACGGTCATGTTGTTTGATGTACCAGTTATGACGCGGTTGATGGAGAGCGAAGCGCGGCGCTTTATTGCGCTG
GTGGATGAGTTTTACGAGCGCCATGTCAAATTAGTGGTGAGTGCAGAAGTGCCGCTGTATGAAATTTATCAGGGCGATCG
GCTGAAGTTTGAGTTCCAGCGTTGCCTGTCACGTCTGCAAGAGATGCAAAGCGAAGAGTATCTGAAGCGCGAGCATTTAG
CGGGTTAA

Upstream 100 bases:

>100_bases
AAGTGGAATCCCGACTGCATATCGCGTAGTGTAGAACGGCCTTTTTTTCGTCAACCGTGAACAACGGCGCACCGATTATT
CAAGGAATAACAATAAGATC

Downstream 100 bases:

>100_bases
AACCTGCCACAAATCACAAAAAGGGGTCGATCTTTGACCCCGACTTCTCTATAATCCTGCGACCCCACGTTACAAGAAAG
TTTTTTTCCCAAAACTTTTT

Product: ATPase, AFG1 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGV
GRGKTWLMDLFYQSLPGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLHDETRAQMDKLW
LALAGGKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIAL
VDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG

Sequences:

>Translated_375_residues
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGV
GRGKTWLMDLFYQSLPGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLHDETRAQMDKLW
LALAGGKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIAL
VDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG
>Mature_375_residues
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGV
GRGKTWLMDLFYQSLPGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLHDETRAQMDKLW
LALAGGKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIAL
VDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG

Specific function: Unknown

COG id: COG1485

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AFG1 ATPase family

Homologues:

Organism=Homo sapiens, GI21918872, Length=433, Percent_Identity=33.4872979214781, Blast_Score=224, Evalue=1e-58,
Organism=Escherichia coli, GI1789627, Length=375, Percent_Identity=100, Blast_Score=780, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17505769, Length=416, Percent_Identity=33.8942307692308, Blast_Score=246, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6320783, Length=401, Percent_Identity=28.927680798005, Blast_Score=162, Evalue=7e-41,
Organism=Drosophila melanogaster, GI20129913, Length=427, Percent_Identity=31.1475409836066, Blast_Score=191, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHCM_ECO57 (P64613)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A91142
- PIR:   D85987
- RefSeq:   NP_289800.1
- RefSeq:   NP_312132.1
- ProteinModelPortal:   P64613
- SMR:   P64613
- EnsemblBacteria:   EBESCT00000028179
- EnsemblBacteria:   EBESCT00000057866
- GeneID:   916046
- GeneID:   957298
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4591
- KEGG:   ecs:ECs4105
- GeneTree:   EBGT00050000009203
- HOGENOM:   HBG664131
- OMA:   EFYDRNV
- ProtClustDB:   CLSK880622
- BioCyc:   ECOL83334:ECS4105-MONOMER
- InterPro:   IPR005654
- PANTHER:   PTHR12169

Pfam domain/function: PF03969 AFG1_ATPase

EC number: NA

Molecular weight: Translated: 43064; Mature: 43064

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTPPAPRTSGLMARVGKLW
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQRLHFHRFMLRVHEELTALQ
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
GQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLMKALFARGITLVATSNIPPDE
CCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHH
LYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLHDETRAQMDKLW
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LALAGGKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVML
HHHCCCCCCCCCEEEECCCCCEEECCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHH
FDVPVMTRLMESEARRFIALVDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHH
EMQSEEYLKREHLAG
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTPPAPRTSGLMARVGKLW
CCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
GKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQRLHFHRFMLRVHEELTALQ
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
GQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLMKALFARGITLVATSNIPPDE
CCCCHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHH
LYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLHDETRAQMDKLW
HHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LALAGGKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVML
HHHCCCCCCCCCEEEECCCCCEEECCCCCEEEEEHHHHHHHCCCCCHHHHHHHHHHHHHH
FDVPVMTRLMESEARRFIALVDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHH
EMQSEEYLKREHLAG
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796